cycloleucine has been researched along with Aura in 13 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anticonvulsant activity of (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) (an antagonist of Group I and an agonist of Group II metabotropic glutamate (mGlu) receptors), of (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid ((1S,3S)-ACPD) (an agonist of Group II mGlu receptors), and of L-serine-O-phosphate (an agonist of Group III mGlu receptors) was studied against sound-induced seizures in genetically epilepsy-prone (GEP) rats following bilateral microinjection into the inferior colliculus." | 3.69 | Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats. ( Chapman, AG; Jane, DE; Meldrum, BS; Tang, E; Yip, PK, 1997) |
| "The spread of experimentally kindled seizures in rats results in sustained increases in plasma vasopressin (VP) and VP mRNA in the supraoptic nucleus (SON)." | 1.30 | Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus. ( Al-Ghoul, WM; Greenwood, RS; Meeker, RB, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burke, JP | 1 |
| Hablitz, JJ | 1 |
| Kadowaki, D | 1 |
| Kinno, I | 1 |
| Kadoya, K | 1 |
| Mori, A | 1 |
| Hiramatsu, M | 1 |
| Attwell, PJ | 1 |
| Kaura, S | 1 |
| Sigala, G | 1 |
| Bradford, HF | 1 |
| Croucher, MJ | 1 |
| Jane, DE | 2 |
| Watkins, JC | 1 |
| Holmes, KH | 1 |
| Keele, NB | 2 |
| Shinnick-Gallagher, P | 2 |
| Tang, E | 1 |
| Yip, PK | 1 |
| Chapman, AG | 1 |
| Meldrum, BS | 1 |
| Merlin, LR | 1 |
| Wong, RK | 1 |
| Kim, D | 1 |
| Jun, KS | 1 |
| Lee, SB | 1 |
| Kang, NG | 1 |
| Min, DS | 1 |
| Kim, YH | 1 |
| Ryu, SH | 1 |
| Suh, PG | 1 |
| Shin, HS | 1 |
| Rutecki, PA | 1 |
| Yang, Y | 1 |
| Libri, V | 1 |
| Constanti, A | 1 |
| Postlethwaite, M | 1 |
| Bowery, NG | 1 |
| Al-Ghoul, WM | 1 |
| Meeker, RB | 1 |
| Greenwood, RS | 1 |
| Neugebauer, V | 1 |
| Sheardown, MJ | 1 |
| Taschenberger, H | 1 |
| Roy, BL | 1 |
| Lowe, DA | 1 |
13 other studies available for cycloleucine and Aura
| Article | Year |
|---|---|
Metabotropic glutamate receptor activation decreases epileptiform activity in rat neocortex.
Topics: Aminobutyrates; Animals; Bicuculline; Cerebral Cortex; Cycloleucine; Epilepsy; Evoked Potentials; Fe | 1994 |
(+-)-1-Amino-1,3-cyclopentane-trans-dicarboxylic acid (trans-ACPD) induced inositol triphosphoric acid formation in the brain of iron-induced epileptic rats and epileptic El mice.
Topics: Animals; Brain; Chlorides; Cycloleucine; Disease Models, Animal; Epilepsy; Ferric Compounds; Inosito | 1994 |
Blockade of both epileptogenesis and glutamate release by (1S,3S)-ACPD, a presynaptic glutamate receptor agonist.
Topics: Animals; Cycloleucine; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniqu | 1995 |
Loss of mGluR-mediated hyperpolarizations and increase in mGluR depolarizations in basolateral amygdala neurons in kindling-induced epilepsy.
Topics: Amygdala; Animals; Cycloleucine; Electric Conductivity; Epilepsy; Evoked Potentials; In Vitro Techni | 1996 |
Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats.
Topics: Animals; Behavior, Animal; Cycloleucine; Dose-Response Relationship, Drug; Epilepsy; Female; Glycine | 1997 |
Role of group I metabotropic glutamate receptors in the patterning of epileptiform activities in vitro.
Topics: Animals; Cycloleucine; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Picrotoxin; Receptor | 1997 |
Phospholipase C isozymes selectively couple to specific neurotransmitter receptors.
Topics: Animals; Ataxia; Binding Sites; Brain; Carbachol; Cerebellum; Cycloleucine; Epilepsy; Hippocampus; I | 1997 |
Metabotropic glutamate receptor activation modulates epileptiform activity in the hippocampus.
Topics: 4-Aminopyridine; Adrenergic Antagonists; Animals; Bicuculline; Cholinergic Antagonists; Cycloleucine | 1997 |
Blockade of GABA(B) receptors facilitates muscarinic agonist-induced epileptiform activity in immature rat piriform cortex in vitro.
Topics: Animals; Benzylamines; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Electric Sti | 1998 |
Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus.
Topics: Amygdala; Animals; Calcium; Cerebral Cortex; Cycloleucine; Disease Models, Animal; Epilepsy; Immunoh | 1998 |
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala.
Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antag | 1999 |
Metabotropic glutamate receptor agonists reduce epileptiform activity in the rat cortex.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cycloleucine; Epilepsy; Excitatory Amino Acid Antagonists | 1992 |
Effects of a metabotropic glutamate agonist, trans-ACPD, on cortical epileptiform activity.
Topics: Animals; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Epilepsy; Glutamates; In V | 1992 |