cycloleucine and Amnesia
cycloleucine has been researched along with Amnesia in 2 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The time course of distribution of labeled cyclo(Leu-Gly) in subcellular fractions of mouse brain was also examined, and the concentration of peptide in the synaptosomal fraction was significantly correlated with the degree of protection against puromycin-induced amnesia of a maze-learning test." | 7.66 | Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia. ( Flexner, JB; Flexner, LB; Hoffman, PL; Rainbow, TC; Walter, R, 1979) |
| " The time course of distribution of labeled cyclo(Leu-Gly) in subcellular fractions of mouse brain was also examined, and the concentration of peptide in the synaptosomal fraction was significantly correlated with the degree of protection against puromycin-induced amnesia of a maze-learning test." | 3.66 | Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia. ( Flexner, JB; Flexner, LB; Hoffman, PL; Rainbow, TC; Walter, R, 1979) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hölscher, C | 1 |
| Rainbow, TC | 1 |
| Flexner, JB | 1 |
| Flexner, LB | 1 |
| Hoffman, PL | 1 |
| Walter, R | 1 |
Other Studies
2 other studies available for cycloleucine and Amnesia
| Article | Year |
|---|---|
Inhibitors of metabotropic glutamate receptors produce amnestic effects in chicks.
Topics: Aminobutyrates; Amnesia; Animals; Avoidance Learning; Benzoates; Chickens; Cycloleucine; Cyclopropan | 1994 |
Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia.
Topics: Amnesia; Animals; Brain; Cycloleucine; Dipeptides; Drug Interactions; Half-Life; Humans; Kinetics; M | 1979 |