Page last updated: 2024-10-25

cycloleucine and Amnesia

cycloleucine has been researched along with Amnesia in 2 studies

Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
" The time course of distribution of labeled cyclo(Leu-Gly) in subcellular fractions of mouse brain was also examined, and the concentration of peptide in the synaptosomal fraction was significantly correlated with the degree of protection against puromycin-induced amnesia of a maze-learning test."7.66Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia. ( Flexner, JB; Flexner, LB; Hoffman, PL; Rainbow, TC; Walter, R, 1979)
" The time course of distribution of labeled cyclo(Leu-Gly) in subcellular fractions of mouse brain was also examined, and the concentration of peptide in the synaptosomal fraction was significantly correlated with the degree of protection against puromycin-induced amnesia of a maze-learning test."3.66Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia. ( Flexner, JB; Flexner, LB; Hoffman, PL; Rainbow, TC; Walter, R, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hölscher, C1
Rainbow, TC1
Flexner, JB1
Flexner, LB1
Hoffman, PL1
Walter, R1

Other Studies

2 other studies available for cycloleucine and Amnesia

ArticleYear
Inhibitors of metabotropic glutamate receptors produce amnestic effects in chicks.
    Neuroreport, 1994, May-09, Volume: 5, Issue:9

    Topics: Aminobutyrates; Amnesia; Animals; Avoidance Learning; Benzoates; Chickens; Cycloleucine; Cyclopropan

1994
Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:5

    Topics: Amnesia; Animals; Brain; Cycloleucine; Dipeptides; Drug Interactions; Half-Life; Humans; Kinetics; M

1979
chemdatabank.com