cycloleucine has been researched along with Aging in 27 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the postnatal development of the carrier-mediated transport process by which certain amino acids are absorbed from the air space of the lung into the blood-stream, a solution of the 14C-labeled nonmetabolized amino acid cycloleucine was administered into the lungs of anesthetized rats of various ages and the rate of absorption of the compound measured." | 1.27 | Postnatal development of carrier-mediated absorption of a foreign amino acid from the rat lung. ( Hemberger, JA; Schanker, LS, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (18.52) | 18.7374 |
| 1990's | 17 (62.96) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oppelt, D | 1 |
| Rodnight, R | 1 |
| Horn, J | 1 |
| Fitarelli, D | 1 |
| Kommers, T | 1 |
| Oliveira, D | 1 |
| Wofchuk, S | 1 |
| Segovia, G | 1 |
| Mora, F | 1 |
| Schanker, LS | 1 |
| Hemberger, JA | 1 |
| Parent, A | 1 |
| Rowe, W | 1 |
| Meaney, MJ | 1 |
| Quirion, R | 1 |
| Schoepp, DD | 3 |
| Goldsworthy, J | 1 |
| Johnson, BG | 2 |
| Salhoff, CR | 2 |
| Baker, SR | 1 |
| Holler, T | 1 |
| Cappel, E | 1 |
| Klein, J | 1 |
| Löffelholz, K | 1 |
| Bevilacqua, JA | 1 |
| Downes, CP | 1 |
| Lowenstein, PR | 1 |
| McGahon, B | 2 |
| Lynch, MA | 3 |
| Wright, RA | 1 |
| Burnett, JP | 1 |
| Mayne, NG | 1 |
| Belagaje, R | 1 |
| Wu, S | 1 |
| Monn, JA | 1 |
| Takagi, H | 1 |
| De Barry, J | 2 |
| Kudo, Y | 1 |
| Yoshioka, T | 1 |
| Blue, ME | 1 |
| Martin, LJ | 1 |
| Brennan, EM | 1 |
| Johnston, MV | 1 |
| Jouvenceau, A | 1 |
| Dutar, P | 1 |
| Billard, JM | 1 |
| Golshani, P | 1 |
| Warren, RA | 1 |
| Jones, EG | 1 |
| Fitzjohn, SM | 1 |
| Bortolotto, ZA | 1 |
| Palmer, MJ | 1 |
| Doherty, AJ | 1 |
| Ornstein, PL | 1 |
| Kingston, AE | 1 |
| Lodge, D | 1 |
| Collingridge, GL | 1 |
| Maguire, C | 1 |
| Kelly, A | 1 |
| McGahon, BM | 1 |
| Martin, DS | 1 |
| Horrobin, DF | 1 |
| Brumberg, JC | 1 |
| Nowak, LG | 1 |
| McCormick, DA | 1 |
| Saransaari, P | 1 |
| Oja, SS | 1 |
| Attucci, S | 1 |
| Albani-Torregrossa, S | 1 |
| Moroni, F | 1 |
| Pellegrini-Giampietro, DE | 1 |
| Kern, HL | 1 |
| Ramsey, RB | 1 |
| Fischer, VW | 1 |
| Reynolds, RA | 1 |
| Segal, S | 1 |
| Vecil, GG | 1 |
| Li, PP | 1 |
| Warsh, JJ | 1 |
| Casabona, G | 1 |
| Genazzani, AA | 1 |
| Di Stefano, M | 1 |
| Sortino, MA | 1 |
| Nicoletti, F | 1 |
| Gombos, G | 1 |
| Levy, O | 1 |
| Foulkes, EC | 1 |
| Mort, TL | 1 |
| Buncher, CR | 1 |
| Cotman, C | 1 |
| Monaghan, D | 1 |
2 reviews available for cycloleucine and Aging
| Article | Year |
|---|---|
Transport of organic solutes in the lens.
Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Calcium; Carbohydrate Meta | 1979 |
Multiple excitatory amino acid receptor regulation of intracellular Ca2+. Implications for aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Brain Chemistry; Calcium; Cycloleucine; Humans; Phosphatidylinositols; Rec | 1989 |
25 other studies available for cycloleucine and Aging
| Article | Year |
|---|---|
Role of intracellular calcium stores on the effect of metabotropic glutamate receptors on phosphorylation of glial fibrillary acidic protein in hippocampal slices from immature rats.
Topics: Aging; Animals; Calcium; Cycloleucine; Glial Fibrillary Acidic Protein; Hippocampus; In Vitro Techni | 2004 |
Effects of the metabotropic glutamate receptor agonist, ACPD, on the extracellular concentrations of GABA and acetylcholine in the prefrontal cortex of the rat during the normal process of aging.
Topics: Acetylcholine; Age Factors; Aging; Analysis of Variance; Animals; Cycloleucine; Dose-Response Relati | 2005 |
Postnatal development of carrier-mediated absorption of a foreign amino acid from the rat lung.
Topics: Absorption; Aging; Amino Acids; Animals; Animals, Newborn; Carbon Radioisotopes; Cycloleucine; Femal | 1984 |
Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors.
Topics: Aging; Animals; Behavior, Animal; Carbachol; Cognition Disorders; Cycloleucine; Diglycerides; Inosit | 1995 |
3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus.
Topics: Aging; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Do | 1994 |
Glutamate activates phospholipase D in hippocampal slices of newborn and adult rats.
Topics: Aging; Animals; Animals, Newborn; Cycloleucine; Enzyme Activation; Glutamates; Glutamic Acid; Hippoc | 1993 |
Transiently selective activation of phosphoinositide turnover in layer V pyramidal neurons after specific mGluRs stimulation in rat somatosensory cortex during early postnatal development.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Carbachol; Cycloleucine; Female; Lithium; Male; P | 1995 |
The synergism between ACPD and arachidonic acid on glutamate release in hippocampus is age-dependent.
Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glut | 1996 |
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Dr | 1996 |
The t-ACPD-induced current response in rat cerebellum.
Topics: Aging; Animals; Cerebellum; Cycloleucine; Evoked Potentials; Gene Expression Regulation, Development | 1993 |
Ontogeny of non-NMDA glutamate receptors in rat barrel field cortex: I. Metabotropic receptors.
Topics: Aging; Animals; Animals, Newborn; Autoradiography; Cycloleucine; Gene Expression Regulation, Develop | 1997 |
Is activation of the metabotropic glutamate receptors impaired in the hippocampal CA1 area of the aged rat?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists | 1997 |
Progression of change in NMDA, non-NMDA, and metabotropic glutamate receptor function at the developing corticothalamic synapse.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; | 1998 |
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity.
Topics: Aging; Amino Acids; Animals; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Criceti | 1998 |
Activation of p42 mitogen-activated protein kinase by arachidonic acid and trans-1-amino-cyclopentyl-1,3- dicarboxylate impacts on long-term potentiation in the dentate gyrus in the rat: analysis of age-related changes.
Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Dentate Gyrus; Drug Synergism; Electric Stimulation; | 1999 |
Age-related changes in synaptic function: analysis of the effect of dietary supplementation with omega-3 fatty acids.
Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Dentate Gyrus; Docosahexaenoic Acids; Eating; Excita | 1999 |
Ionic mechanisms underlying repetitive high-frequency burst firing in supragranular cortical neurons.
Topics: Action Potentials; Aging; Animals; Calcium; Chelating Agents; Cycloleucine; Egtazic Acid; Female; Fe | 2000 |
Involvement of metabotropic glutamate receptors in ischemia-induced taurine release in the developing and adult hippocampus.
Topics: Aging; Animals; Brain Ischemia; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitat | 2000 |
Metabotropic glutamate receptors stimulate phospholipase D via different pathways in the adult and neonate rat hippocampus.
Topics: Aging; Animals; Animals, Newborn; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Kinetics; Metho | 2001 |
Effect of 1-aminocyclopentane-1-carboxylic acid (cycloleucine) on developing rat central nervous system phospholipids.
Topics: Aging; Amino Acids; Animals; Central Nervous System; Cycloleucine; Female; Male; Myelin Sheath; Phos | 1978 |
Regulatory characteristics of amino acid transport in newborn rat renal cortex cells.
Topics: Aging; Amino Acids; Aminoisobutyric Acids; Anaerobiosis; Animals; Animals, Newborn; Biological Trans | 1976 |
Evidence for metabotropic excitatory amino acid receptor heterogeneity: developmental and brain regional studies.
Topics: Aging; Alanine; Animals; Animals, Newborn; Brain; Cycloleucine; Drug Interactions; Male; Phosphatidy | 1992 |
Developmental changes in the modulation of cyclic AMP formation by the metabotropic glutamate receptor agonist 1S,3R-aminocyclopentane-1,3-dicarboxylic acid in brain slices.
Topics: Aging; Animals; Animals, Newborn; Brain; Colforsin; Cyclic AMP; Cycloleucine; Dose-Response Relation | 1992 |
Developmental changes of EAA metabotropic receptor activity in rat cerebellum.
Topics: Aging; Animals; Cerebellum; Cycloleucine; Hydrolysis; Inositol; Inositol Phosphates; Rats; Rats, Wis | 1992 |
Intestinal cadmium permeability in mature and immature rats.
Topics: Aging; Animals; Cadmium; Cycloleucine; Ethanol; Jejunum; Male; Mucus; Permeability; Rats; Rats, Inbr | 1991 |