cycloleucine and Acute Brain Injuries studies

cycloleucine and Acute Brain Injuries

Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.

Research Excerpts

Excerpt	Relevance	Reference
"1S,3R-ACPD-induced seizures were antagonized by systemic administration of dantrolene, an inhibitor of intracellular calcium mobilization, but not by the ionotropic glutamate antagonists MK-801 or GYKI-52466."	1.29	Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist. ( Fix, AS; McDonald, JW; Schoepp, DD; Tizzano, JP, 1993)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

3 (75.00)

18.2507

2000's

1 (25.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Delahunty, TM	1
Jiang, JY	1
Black, RT	1
Lyeth, BG	1
McDonald, JW	1
Fix, AS	1
Tizzano, JP	1
Schoepp, DD	1
Weber, JT	2
Rzigalinski, BA	2
Willoughby, KA	2
Moore, SF	1
Ellis, EF	2
Floyd, CL	1
Sitterding, HA	1

Studies

Delahunty, TM

Jiang, JY

Black, RT

Lyeth, BG

McDonald, JW

Fix, AS

Tizzano, JP

Schoepp, DD

Weber, JT

Rzigalinski, BA

Willoughby, KA

Moore, SF

Ellis, EF

Floyd, CL

Sitterding, HA

Other Studies

4 other studies available for cycloleucine and Acute Brain Injuries

Article	Year
Differential modulation of carbachol and trans-ACPD-stimulated phosphoinositide turnover following traumatic brain injury. Neurochemical research, 1995, Volume: 20, Issue:4 Topics: Animals; Brain Injuries; Carbachol; Cycloleucine; Male; Neurotoxins; Phosphatidylinositols; Rats; Ra	1995
Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:10 Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Brain Injuries; Cell Nucleus; Corpu	1993
Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons. Cell calcium, 1999, Volume: 26, Issue:6 Topics: Animals; Brain Injuries; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cycloleucine;	1999
Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling. Glia, 2001, Volume: 33, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cells, Cultured; Cycloleucine; Estrenes; Extr	2001

Article

Year

Differential modulation of carbachol and trans-ACPD-stimulated phosphoinositide turnover following traumatic brain injury.

Neurochemical research, 1995, Volume: 20, Issue:4

Topics: Animals; Brain Injuries; Carbachol; Cycloleucine; Male; Neurotoxins; Phosphatidylinositols; Rats; Ra

1995

Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:10

Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Brain Injuries; Cell Nucleus; Corpu

1993

Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons.

Cell calcium, 1999, Volume: 26, Issue:6

Topics: Animals; Brain Injuries; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cycloleucine;

1999

Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling.

Glia, 2001, Volume: 33, Issue:1

Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cells, Cultured; Cycloleucine; Estrenes; Extr

2001