cyclohexyl methylphosphonofluoridate has been researched along with Organophosphorus Poisoning in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 11 (44.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalisiak, J; Kovarik, Z; Maček Hrvat, N; Radić, Z; Sharpless, KB; Šinko, G; Taylor, P | 1 |
| Escher, B; Job, L; Köhler, A; Skerra, A; Worek, F | 1 |
| Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM | 1 |
| Bird, M; Green, AC; Kassa, J; Tattersall, JEH; Timperley, CM; Williams, RL | 1 |
| Amend, N; Thiermann, H; Wille, T; Worek, F | 1 |
| Thiermann, H; Von Der Wellen, J; Wille, T; Worek, F | 1 |
| Kubik, S; Seeger, T; Thiermann, H; Wille, T; Worek, F; Zengerle, M | 1 |
| Aas, P; Enger, S; Mariussen, E; Myhrer, T | 1 |
| Bajgar, J; Jun, D; Karasova, J; Kassa, J; Kuca, K | 1 |
| Bajgar, J; Karasova, J; Kassa, J; Kuca, K; Musilek, K | 1 |
| Bajgar, J; Karasova, JZ; Kassa, J; Kuca, K; Musilek, K; Tesarova, S | 1 |
| Karasova, JZ; Kassa, J; Kuca, K; Musilek, K | 1 |
| Cashman, JR; Kalisiak, J; Ralph, EC; Zhang, J | 1 |
| Hamilton, MG; Lundy, PM; Mikler, J; Sawyer, TW | 1 |
| Estour, F; Gouhier, G; Kalakuntla, RK; Lafont, O; Le Provost, R; Letort, S; Müller, S; Reiter, G; Wille, T; Worek, F | 1 |
| Krejcová-Kunesová, G; Kuca, K; Sevelová, L | 1 |
| Berger, BJ; Davidson, C; Hamilton, MG; Hill, I; Lecavalier, P; Lundy, PM; Vair, C; Weatherby, KL | 1 |
| Bartosová, L; Kuca, K; Kunesová, G; Vachek, J | 1 |
| Szinicz, L; Thiermann, H; Worek, F | 1 |
| Bartosová, L; Kuca, K; Kunesová, G | 1 |
| Jun, D; Kassa, J; Kuca, K | 1 |
| Humlicek, V; Kassa, J | 1 |
| Clement, JG | 2 |
| Dochterman, LW; Gresham, VC; Kaminskis, A; Koplovitz, I; Stewart, JR | 1 |
1 review(s) available for cyclohexyl methylphosphonofluoridate and Organophosphorus Poisoning
| Article | Year |
|---|---|
Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning.
Topics: Antidotes; Chemical Warfare Agents; Humans; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman | 2011 |
24 other study(ies) available for cyclohexyl methylphosphonofluoridate and Organophosphorus Poisoning
| Article | Year |
|---|---|
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; GPI-Linked Proteins; Humans; Kinetics; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Protein Conformation; Sarin; Structure-Activity Relationship | 2020 |
A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds.
Topics: Antidotes; Bacterial Proteins; Caulobacteraceae; Drug Stability; Enzyme Stability; Hot Temperature; Mutation; Nerve Agents; Organophosphate Poisoning; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidation-Reduction; Phosphoric Triester Hydrolases; Protein Denaturation; Recombinant Proteins; Sarin; Soman | 2020 |
Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment.
Topics: Animals; Antidotes; Chemical Warfare Agents; Cholinesterase Reactivators; Lethal Dose 50; Male; Mice; Nicotinic Antagonists; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman; Time Factors | 2020 |
Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice.
Topics: Animals; Atropine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Time Factors | 2018 |
The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM).
Topics: Action Potentials; Antidotes; Cell Culture Techniques; Cells, Cultured; Chemical Warfare Agents; Humans; Induced Pluripotent Stem Cells; Microelectrodes; Myocytes, Cardiac; Nerve Agents; Organophosphate Poisoning; Organophosphorus Compounds | 2019 |
Investigations of kinetic interactions between lipid emulsions, hydroxyethyl starch or dextran and organophosphorus compounds.
Topics: Biodegradation, Environmental; Chemical Warfare Agents; Cholinesterase Inhibitors; Dextrans; Emulsions; Erythrocytes; Half-Life; Humans; Hydroxyethyl Starch Derivatives; Kinetics; Malathion; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Pesticides | 2013 |
Effectiveness of a substituted β-cyclodextrin to prevent cyclosarin toxicity in vivo.
Topics: Acetylcholinesterase; Animals; Antidotes; beta-Cyclodextrins; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cytoprotection; Erythrocytes; Guinea Pigs; Injections, Intravenous; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphorus Compounds; Time Factors | 2014 |
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman | 2015 |
A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats.
Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Enzyme Reactivators; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Rats; Rats, Wistar; Soman | 2008 |
An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
Topics: Animals; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Molecular Structure; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Rats; Rats, Wistar; Treatment Outcome | 2009 |
Evaluation of the neuroprotective efficacy of newly developed oximes (K206, K269) and currently available oximes (obidoxime, HI-6) in cyclosarin-poisoned rats.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Muscarinic Antagonists; Neuroprotective Agents; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar | 2009 |
A comparison of reactivating and therapeutic efficacy of newly-developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
Topics: Acetylcholinesterase; Animals; Cholinesterase Reactivators; Male; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Rats; Rats, Wistar | 2009 |
Amidine-oximes: reactivators for organophosphate exposure.
Topics: Acetylcholinesterase; Amidines; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterases; Enzyme Reactivators; Female; Humans; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Permeability; Recombinant Proteins; Sarin; Soman; Structure-Activity Relationship | 2011 |
Functionalized cyclodextrins bearing an alpha nucleophile--a promising way to degrade nerve agents.
Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Cyclodextrins; Humans; Inactivation, Metabolic; Molecular Structure; Organophosphate Poisoning; Organophosphorus Compounds | 2013 |
Antidotal treatment of GF-agent intoxication in mice with bispyridinium oximes.
Topics: Animals; Antidotes; Atropine; Disease Models, Animal; Female; Injections, Intramuscular; Lethal Dose 50; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Structure-Activity Relationship | 2005 |
The pharmacokinetics and pharmacodynamics of two HI-6 salts in swine and efficacy in the treatment of GF and soman poisoning.
Topics: Animals; Atropine; Chemical Warfare Agents; Dose-Response Relationship, Drug; Guinea Pigs; Male; Neuroprotective Agents; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Soman; Swine; Time Factors | 2005 |
Therapeutic efficacy of different antidotal mixtures against poisoning with GF-agent in mice.
Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Female; Mice; Organophosphate Poisoning; Organophosphorus Compounds; Oximes | 2004 |
Estimation of oxime efficacy in nerve agent poisoning: a kinetic approach.
Topics: Acetylcholinesterase; Antidotes; Humans; Kinetics; Neurons; Neurotoxins; Organophosphate Poisoning; Organophosphorus Compounds; Oximes | 2005 |
Effectivity of new acetylcholinesterase reactivators in treatment of cyclosarin poisoning in mice and rats.
Topics: Animals; Cholinesterase Reactivators; Female; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats | 2005 |
A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats.
Topics: Animals; Antidotes; Brain; Butanes; Cholinesterase Reactivators; Drug Evaluation, Preclinical; Male; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Structure-Activity Relationship | 2007 |
A comparison of the potency of newly developed oximes (K074, K075) and currently available oximes (obidoxime, trimedoxime, HI-6) to counteract acute toxic effects of tabun and cyclosarin in mice.
Topics: Animals; Antidotes; Atropine; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lethal Dose 50; Male; Mice; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Oximes; Poisoning; Pyridinium Compounds; Trimedoxime | 2008 |
Toxicity of the combined nerve agents GB/GF in mice: efficacy of atropine and various oximes as antidotes.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Drug Synergism; Injections, Subcutaneous; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Poisoning; Sarin | 1994 |
Evaluation of the toxicity, pathology, and treatment of cyclohexylmethylphosphonofluoridate (CMPF) poisoning in rhesus monkeys.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide | 1992 |
Efficacy of various oximes against GF (cyclohexyl methylphosphonofluoridate) poisoning in mice.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; In Vitro Techniques; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nervous System Diseases; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds | 1992 |