Page last updated: 2024-08-17

cycloheximide and Parkinson Disease

cycloheximide has been researched along with Parkinson Disease in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greene, LA; Jackson-Lewis, V; Jin, ZH; Malagelada, C; Przedborski, S1
Arawaka, S; Fukushima, S; Hara, S; Kato, T; Koyama, S; Machiya, Y; Sakamoto, M; Sato, H1
Anar, B; Bonifati, V; Bronner, IF; Cannella, M; Heutink, P; Hoogeveen, A; Macedo, MG; Rizzu, P; Squitieri, F1
Beyer, K; Görner, K; Haass, C; Holtorf, E; Kahle, PJ; Nuscher, B; Odoy, S; Regula, JT; Yamamoto, A1
Di Monte, DA; Ethell, DW; Fei, Q; McCormack, AL1
Agid, Y; Anglade, P; Michel, PP; Ruberg, M; Vyas, S1
Barzilai, A; Melamed, E; Offen, D; Shirvan, A; Zilkha-Falb, R; Ziv, I1
Dostert, P; Hashizume, Y; Kasamatsu, T; Kohda, K; Maruyama, W; Naoi, M; Takahashi, T1
Jimenez Del Rio, M; Velez-Pardo, C1

Other Studies

9 other study(ies) available for cycloheximide and Parkinson Disease

ArticleYear
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jan-20, Volume: 30, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Cell Death; Cycloheximide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factor; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; PC12 Cells; Protein Serine-Threonine Kinases; Rats; Serine; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Transcription Factors; Transfection; Tyrosine 3-Monooxygenase

2010
Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
    The Journal of biological chemistry, 2010, Dec-24, Volume: 285, Issue:52

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Cell Line, Tumor; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Lewy Bodies; Neurons; Okadaic Acid; Parkinson Disease; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Phosphatase 1; Protein Phosphatase 2; Protein Synthesis Inhibitors; Rabbits; Ubiquitin

2010
The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes.
    Human molecular genetics, 2003, Nov-01, Volume: 12, Issue:21

    Topics: Animals; Chlorocebus aethiops; COS Cells; Cycloheximide; Dimerization; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Lymphocytes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins; Parkinson Disease; Protein Deglycase DJ-1; Protein Denaturation; Protein Inhibitors of Activated STAT; Protein Synthesis Inhibitors; Synucleins

2003
Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Cell Line; Circular Dichroism; Cycloheximide; Cysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Escherichia coli; Gene Deletion; Humans; Intracellular Signaling Peptides and Proteins; Leupeptins; Mass Spectrometry; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Neurons; Oncogene Proteins; Parkinson Disease; Point Mutation; Proteasome Endopeptidase Complex; Protein Conformation; Protein Deglycase DJ-1; Protein Folding; Protein Structure, Secondary; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Time Factors

2004
Paraquat neurotoxicity is mediated by a Bak-dependent mechanism.
    The Journal of biological chemistry, 2008, Feb-08, Volume: 283, Issue:6

    Topics: Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Caspase 3; Cell Survival; Cycloheximide; Gene Expression Regulation; Herbicides; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Paraquat; Parkinson Disease; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2

2008
Morphological and molecular characterization of the response of differentiated PC12 cells to calcium stress.
    The European journal of neuroscience, 1994, Apr-01, Volume: 6, Issue:4

    Topics: Animals; Apoptosis; Calcimycin; Calcium; Cell Differentiation; Cell Survival; Cycloheximide; DNA; DNA Damage; Dopamine; Dose-Response Relationship, Drug; Humans; Microscopy, Electron; Models, Neurological; Neurites; Neurons; Parkinson Disease; PC12 Cells; Tyrosine 3-Monooxygenase

1994
Levodopa induces apoptosis in cultured neuronal cells--a possible accelerator of nigrostriatal degeneration in Parkinson's disease?
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:1

    Topics: Animals; Antioxidants; Antiparkinson Agents; Apoptosis; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Corpus Striatum; Cycloheximide; Dactinomycin; Flow Cytometry; Ganglia, Sympathetic; Humans; Levodopa; Microscopy, Fluorescence; Nerve Degeneration; Neurons; Parkinson Disease; Substantia Nigra

1997
An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:1

    Topics: Antioxidants; Apoptosis; Carcinogens; Catalase; Cycloheximide; DNA Damage; Dopamine; Free Radicals; Humans; Microscopy, Fluorescence; Neuroblastoma; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Parkinson Disease; Protein Synthesis Inhibitors; Salsoline Alkaloids; Selegiline; Semicarbazides; Stereoisomerism; Tetrahydroisoquinolines; Tumor Cells, Cultured

1997
17 beta-estradiol protects lymphocytes against dopamine and iron-induced apoptosis by a genomic-independent mechanism. Implication in Parkinson's disease.
    General pharmacology, 2000, Volume: 35, Issue:1

    Topics: Adult; Apoptosis; Cycloheximide; Dactinomycin; DNA Fragmentation; Dopamine; Electrophoresis, Agar Gel; Estradiol; Genomics; Humans; Hydrogen Peroxide; Iron; Lymphocytes; Male; Parkinson Disease; Predictive Value of Tests; Protein Synthesis Inhibitors; Receptors, Estrogen

2000