Page last updated: 2024-08-17

cycloheximide and Nerve Degeneration

cycloheximide has been researched along with Nerve Degeneration in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.24)18.7374
1990's15 (51.72)18.2507
2000's9 (31.03)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ampo, K; Kadono, C; Kiryu-Seo, S; Kiyama, H; Konishi, H; Maeda, M; Ohba, N1
Achsel, T; Angelini, DF; Bernardi, G; Carrì, MT; Di Penta, A; Maracchioni, A; Totaro, A1
Akaike, A; Fujimoto, S; Katsuki, H; Kume, T; Ohnishi, M; Takagi, M1
Harmar, A; Keen, P; Schofield, JG1
Bonfanti, L; Liu, XH; Maffei, L; Rabacchi, SA1
Choi, MK; Fahrbach, SE; Truman, JW1
Bothwell, M; Canady, KS; Garden, GA; Lurie, DI; Rubel, EW1
Agid, Y; Brugg, B; Michel, PP; Ruberg, M1
Ando, M; Fujita, K; Kakita, M; Nagata, Y; Yamauchi, M1
Coyle, JT; Getz, RL; Konradi, C; Leveque, JC; Simonian, NA1
Anderson, AJ; Cotman, CW; Cribbs, DH; Kreng, VM1
Barzilai, A; Melamed, E; Offen, D; Shirvan, A; Zilkha-Falb, R; Ziv, I1
Groscurth, P; Klockgether, T; Löschmann, PA; Müller, I; Schulz, JB; Weller, M; Wüllner, U1
Choi, DW; DeMaro, JA; Gwag, BJ; Jacquin, M; Koh, JY; Ying, HS1
Gwag, BJ; Jou, I; Park, EC1
Baudry, M; Liu, W; Rong, Y; Schreiber, SS1
Grammas, P; Moore, P; Weigel, PH1
Archer, F; Finn, JT; Raff, MC; Siman, R; Srinivasan, A; Weil, M1
Hill, IE; MacManus, JP; Murray, C; Rasquinha, I; Richard, J1
Camandola, S; Mattson, MP; Poli, G1
Aoyama, M; Asai, K; Kato, T; Miura, Y; Miyachi, T; Mizuno, H; Togari, H; Tsuiki, H; Wada, Y; Yamamoto, N; Yokoi, T1
Castagné, V; Clarke, PG; Lefèvre, K1
Cui, XF; Hatakeyama, M; Imaizumi, T; Kimura, D; Kumagai, M; Matsumiya, T; Sakaki, H; Sato, Y; Satoh, K; Shibata, T; Tamo, W; Tanji, K; Yoshida, H1
Graff, GL; Gueuning, C1
Minneman, KP1
Cotman, CW; Koh, JY1
Koike, T1
Albuquerque, EX; Onur, R; Sansone, FM; Warnick, JE1
Goodman, R; McKelvy, J; Osinchak, J; Sachs, H1

Other Studies

29 other study(ies) available for cycloheximide and Nerve Degeneration

ArticleYear
The p53-independent nuclear translocation of cyclin G1 in degenerating neurons by ischemic and traumatic insults.
    Experimental neurology, 2005, Volume: 193, Issue:2

    Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Cells, Cultured; Cyclin G; Cyclin G1; Cyclins; Cycloheximide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Fluoresceins; Fluorescent Dyes; Gene Expression Regulation; Gerbillinae; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Kainic Acid; Mice; Mice, Knockout; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Degeneration; Neurons; Organic Chemicals; Phosphopyruvate Hydratase; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors; Tumor Suppressor Protein p53

2005
Mitochondrial damage modulates alternative splicing in neuronal cells: implications for neurodegeneration.
    Journal of neurochemistry, 2007, Volume: 100, Issue:1

    Topics: Adenosine Triphosphate; Alternative Splicing; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glioma; Humans; Mitochondria; Nerve Degeneration; Neuroblastoma; Neurons; Neurotoxins; Paraquat; Protein Synthesis Inhibitors; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2007
Involvement of thrombin and mitogen-activated protein kinase pathways in hemorrhagic brain injury.
    Experimental neurology, 2007, Volume: 206, Issue:1

    Topics: Animals; Arginine; Brain; Brain Damage, Chronic; Cell Death; Cerebral Hemorrhage; Cycloheximide; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gliosis; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 1; MAP Kinase Signaling System; Microglia; Nerve Degeneration; Neurons; Neuroprotective Agents; Pipecolic Acids; Platelet Aggregation Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombin

2007
Cycloheximide-sensitive synthesis of substance P by isolated dorsal root ganglia.
    Nature, 1980, Mar-20, Volume: 284, Issue:5753

    Topics: Animals; Capsaicin; Cycloheximide; Ganglia, Spinal; Nerve Degeneration; Rabbits; Substance P

1980
Apoptotic cell death induced by optic nerve lesion in the neonatal rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:9

    Topics: Animals; Animals, Inbred Strains; Animals, Newborn; Apoptosis; Axons; Cell Survival; Cycloheximide; Dactinomycin; Denervation; DNA Damage; Nerve Degeneration; Optic Nerve; Rats; Retinal Ganglion Cells

1994
Inhibitory effects of actinomycin D and cycloheximide on neuronal death in adult Manduca sexta.
    Journal of neurobiology, 1994, Volume: 25, Issue:1

    Topics: Animals; Cell Death; Cells, Cultured; Cycloheximide; Dactinomycin; Ecdysterone; Ganglia, Invertebrate; Histocytochemistry; Larva; Moths; Motor Neurons; Nerve Degeneration; Nerve Tissue Proteins; Neurons

1994
A biphasic change in ribosomal conformation during transneuronal degeneration is altered by inhibition of mitochondrial, but not cytoplasmic protein synthesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:4

    Topics: Afferent Pathways; Animals; Antibodies, Monoclonal; Brain Stem; Cell Nucleolus; Cell Nucleus; Chickens; Cochlear Nerve; Cochlear Nucleus; Cycloheximide; Cytoplasm; Kinetics; Microscopy, Electron; Mitochondria; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Ribosomes; RNA, Ribosomal; Synapses; Time Factors

1994
Ceramide induces apoptosis in cultured mesencephalic neurons.
    Journal of neurochemistry, 1996, Volume: 66, Issue:2

    Topics: Animals; Apoptosis; Bucladesine; Cells, Cultured; Ceramides; Cycloheximide; Mesencephalon; Nerve Degeneration; Neurons; Rats; Rats, Wistar

1996
Induction of tissue transglutaminase in rat superior cervical sympathetic ganglia following in vitro stimulation of retinoic acid.
    Neuroscience research, 1996, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents; Axons; Cycloheximide; Dactinomycin; Female; Kinetics; Male; Nerve Degeneration; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Superior Cervical Ganglion; Sympathectomy; Synaptic Transmission; Transglutaminases; Tretinoin

1996
Kainate induces apoptosis in neurons.
    Neuroscience, 1996, Volume: 74, Issue:3

    Topics: Animals; Anisomycin; Apoptosis; Aurintricarboxylic Acid; Cell Nucleus; Cerebellum; Cycloheximide; Dactinomycin; DNA; Electrophoresis, Agar Gel; Kainic Acid; Kinetics; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley

1996
Cross-linking of concanavalin A receptors on cortical neurons induces programmed cell death.
    Neuroscience, 1996, Volume: 75, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Concanavalin A; Cycloheximide; Dactinomycin; Gene Expression Regulation; Genes, jun; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptor Aggregation; Receptors, Concanavalin A; Signal Transduction

1996
Levodopa induces apoptosis in cultured neuronal cells--a possible accelerator of nigrostriatal degeneration in Parkinson's disease?
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:1

    Topics: Animals; Antioxidants; Antiparkinson Agents; Apoptosis; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Corpus Striatum; Cycloheximide; Dactinomycin; Flow Cytometry; Ganglia, Sympathetic; Humans; Levodopa; Microscopy, Fluorescence; Nerve Degeneration; Neurons; Parkinson Disease; Substantia Nigra

1997
Evidence for an active type of cell death with ultrastructural features distinct from apoptosis: the effects of 3-acetylpyridine neurotoxicity.
    Neuroscience, 1997, Volume: 81, Issue:3

    Topics: Animals; Apoptosis; Cell Death; Cerebellum; Cycloheximide; Dactinomycin; Glutathione; Immunohistochemistry; Microscopy, Electron; Mitochondria; Nerve Degeneration; Neurons; Neurotoxins; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

1997
Slowly triggered excitotoxicity occurs by necrosis in cortical cultures.
    Neuroscience, 1997, Volume: 77, Issue:2

    Topics: Animals; Apoptosis; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acids; Mice; Microscopy, Electron; Necrosis; Nerve Degeneration; Neurons; Protein Synthesis Inhibitors

1997
Nerve growth factor potentiates the oxidative necrosis of striatal cholinergic neurons.
    Neuroreport, 1998, Mar-09, Volume: 9, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholinesterase; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Buthionine Sulfoximine; Cells, Cultured; Chromans; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Drug Synergism; Fetus; Free Radicals; Iron; Necrosis; Nerve Degeneration; Nerve Growth Factors; Neuroglia; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley

1998
Status epilepticus induces p53 sequence-specific DNA binding in mature rat brain.
    Brain research. Molecular brain research, 1999, Jan-08, Volume: 63, Issue:2

    Topics: Animals; Brain; Cycloheximide; Gene Expression Regulation; Genes, p53; Kainic Acid; Male; Nerve Degeneration; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tumor Suppressor Protein p53

1999
Microvessels from Alzheimer's disease brains kill neurons in vitro.
    The American journal of pathology, 1999, Volume: 154, Issue:2

    Topics: Alzheimer Disease; Animals; Brain; Capillaries; Cell Death; Coculture Techniques; Culture Media, Conditioned; Cycloheximide; Humans; Nerve Degeneration; Neurons; PC12 Cells; Rats

1999
Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Feb-15, Volume: 20, Issue:4

    Topics: Animals; Apoptosis; Axons; Caspase 3; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Activation; Ganglia, Spinal; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Growth Factors; Neurons; Optic Nerve; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Wallerian Degeneration

2000
Despite the internucleosomal cleavage of DNA, reactive oxygen species do not produce other markers of apoptosis in cultured neurons.
    Experimental neurology, 2000, Volume: 162, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspases; Cell Nucleus; Cholinesterase Inhibitors; Comet Assay; Cycloheximide; DNA Fragmentation; Enzyme Inhibitors; Female; Free Radical Scavengers; Glutamic Acid; Metalloporphyrins; Molsidomine; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nucleosomes; Oxidation-Reduction; Phenanthrolines; Pregnancy; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staurosporine; Uric Acid

2000
The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons.
    Brain research. Molecular brain research, 2000, Dec-28, Volume: 85, Issue:1-2

    Topics: Aldehydes; Alzheimer Disease; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Lipid Peroxidation; Nerve Degeneration; Neurons; NF-kappa B; Okadaic Acid; Protein Synthesis Inhibitors; Rats; Stroke; Transcription Factor AP-1; Vanadates

2000
Interleukin-1beta induces the expression of lipocortin 1 mRNA in cultured rat cortical astrocytes.
    Neuroscience research, 2001, Volume: 40, Issue:1

    Topics: Animals; Annexin A1; Antibodies; Astrocytes; Brain Injuries; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Fetus; Interleukin-1; MAP Kinase Signaling System; Nerve Degeneration; Neuroprotective Agents; Protein Synthesis Inhibitors; Quinacrine; Rats; Rats, Wistar; RNA, Messenger; Time Factors

2001
Dual role of the NF-kappaB transcription factor in the death of immature neurons.
    Neuroscience, 2001, Volume: 108, Issue:3

    Topics: Animals; Axotomy; Buthionine Sulfoximine; Cell Death; Cellular Senescence; Chick Embryo; Cycloheximide; Eye; Glutathione; Injections; Nerve Degeneration; Neurons; Neuroprotective Agents; NF-kappa B; Proto-Oncogene Proteins c-rel; Retinal Ganglion Cells; Tissue Distribution

2001
Platelet-activating factor enhances the expression of vascular endothelial growth factor in normal human astrocytes.
    Brain research, 2002, Jul-19, Volume: 944, Issue:1-2

    Topics: Anti-Inflammatory Agents; Astrocytes; Brain; Cells, Cultured; Cycloheximide; Deferoxamine; Dexamethasone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Gene Expression Regulation; Humans; Hypoxia, Brain; Iron Chelating Agents; Lymphokines; Nerve Degeneration; Neurons; Platelet Activating Factor; Protein Synthesis Inhibitors; RNA, Messenger; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
[Wallerian degeneration of the rat sciatic nerve. Lack of effect of cycloheximide and of actinomycin D on the increase of radiophosphate incorporation in acid soluble phosphates observed after section of the nerve].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1975, Volume: 169, Issue:3

    Topics: Animals; Cycloheximide; Dactinomycin; Male; Nerve Degeneration; Phosphates; Rats; Sciatic Nerve; Wallerian Degeneration

1975
Postsynaptic induction of serotonin N-acetyltransferase activity and the control of cyclic nucleotide metabolism in organ cultures of the rat pineal.
    Molecular pharmacology, 1977, Volume: 13, Issue:4

    Topics: Acetyltransferases; Adenylyl Cyclases; Animals; Bacterial Toxins; Cyclic AMP; Cyclic GMP; Cycloheximide; Drug Interactions; Enzyme Induction; Male; Nerve Degeneration; Norepinephrine; Nucleotides, Cyclic; Organ Culture Techniques; Ouabain; Phosphoric Diester Hydrolases; Pineal Gland; Potassium; Rats; Serotonin; Synapses; Time Factors; Vibrio cholerae; Xanthines

1977
Programmed cell death: its possible contribution to neurotoxicity mediated by calcium channel antagonists.
    Brain research, 1992, Aug-07, Volume: 587, Issue:2

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Cerebral Cortex; Culture Media; Cycloheximide; Dactinomycin; Female; L-Lactate Dehydrogenase; Mice; Nerve Degeneration; Neuroglia; Neurons; Pregnancy

1992
Molecular and cellular mechanism of neuronal degeneration caused by nerve growth factor deprivation approached through PC12 cell culture.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blotting, Northern; Cell Death; Cycloheximide; Deoxyadenosines; Gene Expression Regulation, Neoplastic; Genes, fos; Male; Mice; Nerve Degeneration; Nerve Growth Factors; Neural Pathways; PC12 Cells; RNA, Messenger

1992
Trophic functions of the neuron. 3. Mechanisms of neurotrophic interactions. The effects of vinblastine and colchicine on neural regulation of muscle.
    Annals of the New York Academy of Sciences, 1974, Mar-22, Volume: 228, Issue:0

    Topics: Acetylcholine; Action Potentials; Adenosine Triphosphatases; Animals; Caffeine; Cell Membrane; Colchicine; Cycloheximide; Electrophysiology; Iontophoresis; Membrane Potentials; Microtubules; Muscle Contraction; Muscles; Nerve Degeneration; Neuromuscular Junction; Peripheral Nerves; Rats; Sarcoplasmic Reticulum; Tetrodotoxin; Time Factors; Vinblastine

1974
Supraoptic neurosecretory neurons of the guinea pig in organ culture. Biosynthesis of vasopressin and neurophysin.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:11

    Topics: Animals; Autoradiography; Cycloheximide; Cystine; Depression, Chemical; Golgi Apparatus; Guinea Pigs; Hypothalamus; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurosecretory Systems; Nissl Bodies; Organ Culture Techniques; Peptide Biosynthesis; Puromycin; Sulfur Isotopes; Tritium; Uridine; Vasopressins

1971