Page last updated: 2024-08-17

cycloheximide and Necrosis

cycloheximide has been researched along with Necrosis in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (14.29)	18.7374
1990's	21 (33.33)	18.2507
2000's	24 (38.10)	29.6817
2010's	9 (14.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bach, S; Baratte, B; Bonnet, M; Comte, A; Delalande, O; Delehouzé, C; Desban, N; Dimanche-Boitrel, MT; Faurez, F; Filliol, A; Gallais, I; Goekjian, P; Le Cann, F; Leverrier-Penna, S; Mettey, Y; Piquet-Pellorce, C; Samson, M; Vandenabeele, P	1
Do, YJ; Jang, KH; Kang, NS; Kim, E; Kim, YG; Kim, YH; Sul, JW	1
Anany, MA; Füllsack, S; Kreckel, J; Otto, C; Rosenthal, A; Siegmund, D; Wajant, H	1
Chan, FK; McQuade, T; Moquin, DM	1
Adam, D; Kalthoff, H; Philipp, S; Plenge, J; Sosna, J	1
Sawai, H	1
Ando, Y; Hakamata, S; Ito, K; Kumagai, K; Manabe, S; Nakayama, H; Teranishi, M	1
De Bock, M; De Geest, BG; De Vuyst, E; Decrock, E; Demeester, J; Leybaert, L; Rogiers, V; Sanders, NN; Vandenbroucke, RE; Vanhaecke, T; Vinken, M	1
Christofferson, DE; Yuan, J	1
Calounova, G; Grujic, M; Melo, FR; Pejler, G; Spirkoski, J	1
Hatayama, T; Ishihara, K; Saito, Y; Yamagishi, N	1
Billerey, C; Bonnotte, B; Fromentin, A; Garrido, C; Kroemer, G; Larmonier, N; Martin, F; Moutet, M; Parcellier, A; Rébé, C; Solary, E	1
Gramsbergen, JB; Kristensen, BW; Noer, H; Noraberg, J; Zimmer, J	1
Allen, SG; Baldwin, RA; Fujikawa, DG; Niquet, J; Wasterlain, CG	1
Chen, HJ; Chen, SD; Cho, CL; Hsu, HC; Huang, HY; Liang, CL; Lu, K; Yang, LC	1
Gauthier, ER; Guérin, PJ	1
Choksi, S; Hur, GM; Kim, YS; Lin, Y; Liu, ZG; Nedospasov, SA; Shen, HM; Tran, JH; Yang, QF	1
Jung, MJ; Kweon, MH; Sung, HC	1
Arvelo, MB; Daniel, S; Ferran, C; Grey, ST; Longo, CR; Mahiou, J; Mottley, C; Patel, VI; Shrikhande, G; Shukri, T; Sun, DW	1
Koike, T; Suzuki, M	1
Benson, BA; Dalmasso, AP; Fogelson, JL; François-Bongarçon, V; Grehan, JF; Levay-Young, BK	1
Chang, YS; Kang, S; Kim, YJ; Koo, SH; Lee, JH; Lee, M; Park, WS; Sung, DK	1
Chen, SP; Hong, JR; Su, YC; Wu, JL	1
Horváth, V; Ondrousková, E; Smarda, J; Soucek, K	1
Ding, WX; Ni, HM; Yin, XM	1
Bastos, Mde L; Carvalho, FD; Dirnagl, U; Lopes, MA; Meisel, A	1
Parry, EW	4
Gabai, VL; Kabakov, AE	1
Akagi, Y; Ito, K; Sawada, S	1
Bergeron, D; Dubé, D; Dufour, M; Govindan, MV; Lambert, RD; Lapointe, J	1
Hoorens, A; Klöppel, G; Pipeleers, D; Van de Casteele, M	1
Aja, TJ; Alnemri, ES; Armstrong, RC; Bai, X; Fritz, LC; Gaur, S; Hoang, KD; Karanewsky, DS; Litwack, G; Tomaselli, KJ	1
MacCabe, JA; Noveroske, JK	1
Aishita, H; Chuang, DM; Ishitani, R; Sunaga, K; Tanaka, M	1
Figiel, I; Kaczmarek, L	1
Choi, DW; Hsu, CY; Jacquin, MF; Kanellopoulos, GK; Kato, H; Kouchoukos, NT; Matsuo, S; Wu, YJ	1
Bradham, C; Brenner, DA; Czaja, MJ; Xu, Y	1
Chang, H; Gonzalez-Crussi, F; Hsueh, W; Qu, XW; Remick, DG; Tan, XD; Wang, H	1
Choi, DW; DeMaro, JA; Gwag, BJ; Jacquin, M; Koh, JY; Ying, HS	1
Gwag, BJ; Jou, I; Park, EC	1
Dostert, P; Kasamatsu, T; Maruyama, W; Naoi, M	1
Maher, P; Tan, S; Wood, M	1
Gwag, BJ; Kim, EY; Kim, YH; Koh, JY; Sohn, S	1
Guo, YL; Kang, B; Williamson, JR; Yang, LJ	1
Blom, WM; de Bont, HJ; Meijerman, I; Mulder, GJ; Nagelkerke, JF	1
Gollahon, KA; Kim, C; Potter, A; Rabinovitch, PS	1
Bogazzi, F; D'Ascoli, F; Di Matola, T; Fenzi, G; Martino, E; Rossi, G; Salzano, S; Vitale, M	1
Chung, JM; Hong, JH; Hur, KC	1
Dobos, KM; King, CH; Quinn, FD; Spotts, EA	1
Choi, D	1
Gwag, BJ; Han, KS; Kang, HJ; Kim, EY; Kwon, HJ; Sohn, S; Yoon, WJ	1
Calabrese, EJ	1
Mizushima, T; Rokutan, K; Tomisato, W; Tsuchiya, T; Tsutsumi, S	1
Castro, JA; de Castro, CR; de Fenos, OM; Diaz Gómez, MI; Ferreyra, EC; Gram, TE; Guarino, AM; Reagan, RL	1
Ben-Ishay, Z; Farber, E	1
Abbott, PJ; Harmon, B; Kerr, JF; Lawson, TA; Searle, J	1
Connelly, LJ; Koff, RS	1
Columbano, A; Coni, P; Curto, M; Faa, G; Giacomini, L; Ledda-Columbano, GM; Oliverio, S; Piacentini, M	1
Bergmann, F; Feinmesser, M; Yagen, B	1
Farber, E; Liang, H; Longnecker, DS; Verbin, RS	1

Reviews

1 review(s) available for cycloheximide and Necrosis

Article	Year
Apoptosis: biphasic dose responses. Critical reviews in toxicology, 2001, Volume: 31, Issue:4-5 Topics: Animals; Antioxidants; Apoptosis; Cycloheximide; Dementia; Dimethylformamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Humans; Melatonin; Necrosis; Nootropic Agents; Protein Synthesis Inhibitors; Radiation Injuries; Staurosporine; Tacrine; Tumor Necrosis Factor-alpha	2001

Other Studies

62 other study(ies) available for cycloheximide and Necrosis

Article	Year
Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis. The FEBS journal, 2017, Volume: 284, Issue:18 Topics: Alkaloids; Animals; Apoptosis; Caspase 3; Cell Line, Transformed; Concanavalin A; Cycloheximide; Fibroblasts; Gene Expression Regulation; Hepatitis, Animal; HT29 Cells; Humans; Imidazoles; Immunologic Factors; Indoles; Jurkat Cells; Male; Mice; Molecular Docking Simulation; Necrosis; Protein Kinase Inhibitors; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Spiro Compounds; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha	2017
A novel RIPK1 inhibitor that prevents retinal degeneration in a rat glaucoma model. Experimental cell research, 2017, 10-01, Volume: 359, Issue:1 Topics: Animals; Apoptosis; Cell Hypoxia; Cells, Cultured; Cycloheximide; Disease Models, Animal; Glaucoma; Glucose; HT29 Cells; Humans; Injections, Intraperitoneal; Ischemia; Male; Mice; Mitochondria; Necrosis; Neuroprotection; Oligopeptides; Oxygen; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Receptor-Interacting Protein Serine-Threonine Kinases; Retinal Degeneration; Retinal Neurons; Tumor Necrosis Factor-alpha	2017
Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosis. Cell death & disease, 2018, 10-22, Volume: 9, Issue:11 Topics: Apoptosis; Caspase 8; Cell Death; Cell Line, Tumor; Cycloheximide; Cytokine TWEAK; Fas-Associated Death Domain Protein; HeLa Cells; Humans; Necrosis; NF-kappa B; Poly I-C; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; TNF Receptor-Associated Death Domain Protein; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha	2018
CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis. PloS one, 2013, Volume: 8, Issue:10 Topics: Animals; Cell Line, Tumor; Cycloheximide; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Gene Expression Regulation; Gene Knockdown Techniques; GTPase-Activating Proteins; Humans; Mice; Necrosis; Oligopeptides; Phosphorylation; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Tumor Necrosis Factor-alpha; Ubiquitination	2013
Homoharringtonine, a clinically approved anti-leukemia drug, sensitizes tumor cells for TRAIL-induced necroptosis. Cell communication and signaling : CCS, 2015, Apr-29, Volume: 13 Topics: Antineoplastic Agents; Cell Line, Tumor; Cycloheximide; Harringtonines; Homoharringtonine; Humans; Necrosis; Neoplasms; Protein Synthesis Inhibitors; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand	2015
Induction of Apoptosis in TNF-Treated L929 Cells in the Presence of Necrostatin-1. International journal of molecular sciences, 2016, Oct-07, Volume: 17, Issue:10 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Cycloheximide; Imidazoles; Indoles; Mice; Necrosis; Poly(ADP-ribose) Polymerases; Tumor Necrosis Factor-alpha	2016
Neutralization of IL-10 exacerbates cycloheximide-induced hepatocellular apoptosis and necrosis. Toxicologic pathology, 2009, Volume: 37, Issue:4 Topics: Animals; Antibodies; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytokines; Data Interpretation, Statistical; Hepatocytes; Interleukin-10; Liver; Liver Diseases; Male; Necrosis; Neutralization Tests; Neutrophil Infiltration; Rats; Rats, Inbred F344; RNA, Messenger; Signal Transduction; Up-Regulation	2009
Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death. Cellular and molecular life sciences : CMLS, 2010, Volume: 67, Issue:6 Topics: Animals; Apoptosis; Connexins; Cycloheximide; Fas Ligand Protein; Gap Junction beta-1 Protein; Hepatocytes; Humans; Ion Channel Gating; Male; Necrosis; Rats; Rats, Sprague-Dawley	2010
Cyclophilin A release as a biomarker of necrotic cell death. Cell death and differentiation, 2010, Volume: 17, Issue:12 Topics: Amino Acid Chloromethyl Ketones; Animals; Biomarkers; Cell Line; Cycloheximide; Cyclophilin A; HMGB1 Protein; Humans; Imidazoles; Indoles; Mice; Necrosis; Tumor Necrosis Factor-alpha	2010
Serglycin proteoglycan promotes apoptotic versus necrotic cell death in mast cells. The Journal of biological chemistry, 2012, May-25, Volume: 287, Issue:22 Topics: Animals; Apoptosis; Blotting, Western; Cell Death; Cycloheximide; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Proteoglycans; Tumor Necrosis Factor-alpha; Vesicular Transport Proteins	2012
Hsp105alpha enhances stress-induced apoptosis but not necrosis in mouse embryonal f9 cells. Journal of biochemistry, 2002, Volume: 132, Issue:2 Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Caspases; Cell Line; Cell Survival; Cycloheximide; Cytochrome c Group; DNA Fragmentation; Embryo, Mammalian; Enzyme Precursors; Etoposide; Hot Temperature; HSP110 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proteins	2002
An atypical caspase-independent death pathway for an immunogenic cancer cell line. Oncogene, 2002, Sep-05, Volume: 21, Issue:39 Topics: Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Apoptosis; Apoptosis Inducing Factor; Caspase Inhibitors; Caspases; Chromatin; Cycloheximide; Cysteine Proteinase Inhibitors; Deoxyribonucleases; Fas Ligand Protein; Flavoproteins; Immunoblotting; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mitochondria; Necrosis; Nucleosomes; Protein Synthesis Inhibitors; Rats; Tumor Cells, Cultured	2002
Colchicine induces apoptosis in organotypic hippocampal slice cultures. Brain research, 2003, Feb-28, Volume: 964, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzimidazoles; Caspase 3; Caspases; Colchicine; Cycloheximide; Dentate Gyrus; Dose-Response Relationship, Drug; Fluorescent Dyes; Immunohistochemistry; Necrosis; Neurons; Neuroprotective Agents; Neurotoxins; Propidium; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors	2003
Hypoxic neuronal necrosis: protein synthesis-independent activation of a cell death program. Proceedings of the National Academy of Sciences of the United States of America, 2003, Mar-04, Volume: 100, Issue:5 Topics: Blotting, Western; Calcium; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Death; Cell Nucleus; Cycloheximide; Detergents; Enzyme Activation; Enzyme Inhibitors; Hypoxia; Immunohistochemistry; Ions; Microscopy, Electron; Mitochondria; Necrosis; Neurons; Octoxynol; Protein Biosynthesis; Protein Synthesis Inhibitors; Sodium Cyanide; Time Factors	2003
Neuroprotective synergy of N-methyl-D-aspartate receptor antagonist (MK801) and protein synthesis inhibitor (cycloheximide) on spinal cord ischemia-reperfusion injury in rats. Journal of neurotrauma, 2003, Volume: 20, Issue:2 Topics: Animals; Apoptosis; Cycloheximide; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Male; Necrosis; Neuroprotective Agents; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spinal Cord	2003
Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen. Journal of cellular biochemistry, 2003, May-01, Volume: 89, Issue:1 Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Azoles; Caspases; Cell Death; Cycloheximide; Cysteine Proteinase Inhibitors; Glutathione Peroxidase; Hybridomas; Isoindoles; Mice; Necrosis; Organoselenium Compounds	2003
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. The Journal of biological chemistry, 2004, Mar-12, Volume: 279, Issue:11 Topics: Animals; Apoptosis; Arabidopsis Proteins; Blotting, Western; Cell Death; Cells, Cultured; Cycloheximide; Embryo, Mammalian; Fatty Acid Desaturases; Fibroblasts; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Necrosis; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Plasmids; Proteins; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Recombinant Proteins; Signal Transduction; Time Factors; TNF Receptor-Associated Factor 2; Transfection; Tumor Necrosis Factor-alpha	2004
Cytoprotective effects of heme oxygenase-1 induction by 3-O-caffeoyl-1-methylquinic acid. Free radical biology & medicine, 2004, Jan-01, Volume: 36, Issue:1 Topics: Acetylcysteine; Animals; Antioxidants; Cattle; Cell Line; Cryoprotective Agents; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Ferritins; Flow Cytometry; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxybenzoates; Molecular Structure; Necrosis; Protoporphyrins; Quinic Acid; Reactive Oxygen Species; RNA, Messenger; tert-Butylhydroperoxide; Time Factors; Up-Regulation	2004
A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. Blood, 2004, Oct-15, Volume: 104, Issue:8 Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Caspase 3; Caspase 6; Caspase 8; Caspase Inhibitors; Caspases; Cattle; Cells, Cultured; Complement System Proteins; Cycloheximide; DNA-Binding Proteins; Endothelial Cells; Enzyme Activation; fas Receptor; Fas-Associated Death Domain Protein; Gene Expression; Hot Temperature; Humans; Intracellular Signaling Peptides and Proteins; Killer Cells, Natural; Mitochondria; Necrosis; NF-kappa B; Nuclear Proteins; Proteins; Signal Transduction; Swine; Tumor Necrosis Factor alpha-Induced Protein 3; Tumor Necrosis Factor-alpha	2004
Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death. Journal of neuroscience research, 2005, May-15, Volume: 80, Issue:4 Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspase 3; Caspase 7; Caspases; Cell Count; Cells, Cultured; Colforsin; Cyclin D1; Cycloheximide; Dihydrotachysterol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Homeostasis; Immunohistochemistry; In Situ Nick-End Labeling; Ionophores; Lactic Acid; Mitochondria; Models, Biological; Necrosis; Nerve Growth Factor; Neurons; Neuroprotective Agents; Peptides; Permeability; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Superior Cervical Ganglion; Time Factors	2005
IL-4 and IL-13 induce protection of porcine endothelial cells from killing by human complement and from apoptosis through activation of a phosphatidylinositide 3-kinase/Akt pathway. Journal of immunology (Baltimore, Md. : 1950), 2005, Aug-01, Volume: 175, Issue:3 Topics: Animals; Apoptosis; CD59 Antigens; Cells, Cultured; Complement Activation; Complement C9; Cycloheximide; Cytotoxicity, Immunologic; Endothelium, Vascular; Humans; Interleukin-13; Interleukin-4; MAP Kinase Signaling System; Necrosis; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Swine; Tumor Necrosis Factor-alpha	2005
Therapeutic window for cycloheximide treatment after hypoxic-ischemic brain injury in neonatal rats. Journal of Korean medical science, 2006, Volume: 21, Issue:3 Topics: Animals; Animals, Newborn; Apoptosis; Brain Ischemia; Cycloheximide; Flow Cytometry; Humans; Hypoxia-Ischemia, Brain; Hypoxia, Brain; Necrosis; Neuroprotective Agents; Oxygen; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley	2006
Anti-Bcl-2 family members, zfBcl-x(L) and zfMcl-1a, prevent cytochrome c release from cells undergoing betanodavirus-induced secondary necrotic cell death. Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:6 Topics: Animals; bcl-X Protein; Caspases; Cell Line; Cycloheximide; Cytochromes c; Enzyme Activation; Fishes; Liver; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Biological; Myeloid Cell Leukemia Sequence 1 Protein; Necrosis; Neoplasm Proteins; Nodaviridae; Phosphatidylserines; Protein Biosynthesis; Proto-Oncogene Proteins c-bcl-2; Viral Proteins; Virus Diseases	2007
Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis. Leukemia research, 2008, Volume: 32, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Blotting, Western; Camptothecin; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Chickens; Cycloheximide; Genes, myb; Humans; Microscopy, Fluorescence; Necrosis; Oxides; Signal Transduction; U937 Cells	2008
Absence of Bax switched MG132-induced apoptosis to non-apoptotic cell death that could be suppressed by transcriptional or translational inhibition. Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:12 Topics: Adenosine Triphosphate; Apoptosis; bcl-2-Associated X Protein; Cycloheximide; Dactinomycin; Endoplasmic Reticulum; HCT116 Cells; Humans; Leupeptins; Necrosis; Polyubiquitin; Proteasome Inhibitors; Protein Biosynthesis; Protein Folding; Protein Structure, Quaternary; Transcription, Genetic; Vacuoles	2007
Doxorubicin induces biphasic neurotoxicity to rat cortical neurons. Neurotoxicology, 2008, Volume: 29, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Necrosis; Neurons; Oligopeptides; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Time Factors	2008
The effect of cycloheximide and carbon tetrachloride in Ehrlich ascites tumour-bearing mice. Gan, 1980, Volume: 71, Issue:3 Topics: Animals; Carbon Tetrachloride; Carcinoma, Ehrlich Tumor; Chemical and Drug Induced Liver Injury; Cycloheximide; Liver; Male; Mice; Mice, Inbred CBA; Necrosis; Protein Biosynthesis	1980
Heat shock-induced accumulation of 70-kDa stress protein (HSP70) can protect ATP-depleted tumor cells from necrosis. Experimental cell research, 1995, Volume: 217, Issue:1 Topics: Adenosine Triphosphate; Animals; Cycloheximide; Hot Temperature; HSP70 Heat-Shock Proteins; Ischemia; Mice; Necrosis; Protein Synthesis Inhibitors; Rotenone; Tumor Cells, Cultured	1995
Radiation-induced apoptosis and necrosis in Molt-4 cells: a study of dose-effect relationships and their modification. International journal of radiation biology, 1993, Volume: 64, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bromodeoxyuridine; Cell Death; Cycloheximide; Isoquinolines; Leukemia, Lymphoid; Necrosis; Piperazines; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured	1993
Biochemical and morphological characterizations of DU-145 cell mortality in rabbit embryo-fetal fluid. Cell proliferation, 1993, Volume: 26, Issue:2 Topics: Animals; Aurintricarboxylic Acid; Body Fluids; Cell Death; Cycloheximide; DNA; Embryo, Mammalian; Female; Flow Cytometry; Humans; Necrosis; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pregnancy; Protein Biosynthesis; Rabbits; Tumor Cells, Cultured	1993
Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program. The Journal of clinical investigation, 1996, Oct-01, Volume: 98, Issue:7 Topics: Animals; Apoptosis; Cell Separation; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Islets of Langerhans; Male; Microscopy, Electron; Microscopy, Fluorescence; Necrosis; Rats	1996
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebellar Cortex; Coumarins; Culture Media, Serum-Free; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Enzyme Precursors; Glutamic Acid; Ketones; Mice; Mice, Inbred C57BL; Necrosis; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Potassium; Protein Synthesis Inhibitors	1997
The control of cell death in the early chick embryo wing bud. Poultry science, 1997, Volume: 76, Issue:1 Topics: Animals; Apoptosis; Chick Embryo; Cycloheximide; Epidermal Growth Factor; Fibroblast Growth Factor 2; Growth Substances; In Vitro Techniques; Insulin-Like Growth Factor II; Mesoderm; Microscopy, Electron; Necrosis; Platelet-Derived Growth Factor; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Wings, Animal	1997
Overexpression of glyceraldehyde-3-phosphate dehydrogenase is involved in low K+-induced apoptosis but not necrosis of cultured cerebellar granule cells. Molecular pharmacology, 1997, Volume: 51, Issue:4 Topics: Animals; Apoptosis; Cells, Cultured; Cerebellum; Cycloheximide; Cytoplasmic Granules; Dactinomycin; Glyceraldehyde-3-Phosphate Dehydrogenases; Necrosis; Oligonucleotides, Antisense; Potassium Deficiency; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger	1997
Orthovanadate induces cell death in rat dentate gyrus primary culture. Neuroreport, 1997, Jul-28, Volume: 8, Issue:11 Topics: Animals; Animals, Newborn; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Cycloheximide; Dentate Gyrus; DNA Fragmentation; Dose-Response Relationship, Drug; Hippocampus; Necrosis; Neurons; Rats; Sodium Azide; Vanadates	1997
Protection of rat spinal cord from ischemia with dextrorphan and cycloheximide: effects on necrosis and apoptosis. The Journal of thoracic and cardiovascular surgery, 1997, Volume: 114, Issue:4 Topics: Animals; Apoptosis; Cycloheximide; Dextrorphan; Excitatory Amino Acid Antagonists; Male; Microscopy, Electron; N-Methylaspartate; Necrosis; Neurons; Paraplegia; Premedication; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Spinal Cord; Time Factors	1997
Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation. The American journal of physiology, 1997, Volume: 273, Issue:4 Topics: Carcinoma, Hepatocellular; Cell Survival; Cycloheximide; DNA Fragmentation; Genes, jun; Genes, Reporter; Glutathione; Humans; Hydrogen Peroxide; Liver; Liver Neoplasms; Luciferases; Necrosis; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1997
Platelet-activating factor (PAF) up-regulates plasma and tissue PAF-acetylhydrolase activity in the rat: effect of cycloheximide. Pediatric research, 1997, Volume: 42, Issue:5 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Cycloheximide; Intestinal Mucosa; Intestines; Male; Necrosis; Phospholipases A; Platelet Activating Factor; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Up-Regulation	1997
Slowly triggered excitotoxicity occurs by necrosis in cortical cultures. Neuroscience, 1997, Volume: 77, Issue:2 Topics: Animals; Apoptosis; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acids; Mice; Microscopy, Electron; Necrosis; Nerve Degeneration; Neurons; Protein Synthesis Inhibitors	1997
Nerve growth factor potentiates the oxidative necrosis of striatal cholinergic neurons. Neuroreport, 1998, Mar-09, Volume: 9, Issue:4 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholinesterase; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Buthionine Sulfoximine; Cells, Cultured; Chromans; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Drug Synergism; Fetus; Free Radicals; Iron; Necrosis; Nerve Degeneration; Nerve Growth Factors; Neuroglia; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley	1998
Oxidation of N-methyl(R)salsolinol: involvement to neurotoxicity and neuroprotection by endogenous catechol isoquinolines. Journal of neural transmission. Supplementum, 1998, Volume: 52 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Corpus Striatum; Cycloheximide; Disease Models, Animal; DNA Damage; Dopamine; Homovanillic Acid; Humans; Hydroxyl Radical; Isoquinolines; Male; Necrosis; Neuroblastoma; Neurons; Neurotoxins; Oxidative Stress; Parkinson Disease, Secondary; Posture; Rats; Rats, Wistar; Salsoline Alkaloids; Stereoisomerism; Substantia Nigra; Tetrahydroisoquinolines; Tumor Cells, Cultured	1998
Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. Journal of neurochemistry, 1998, Volume: 71, Issue:1 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Aurintricarboxylic Acid; Buthionine Sulfoximine; Cell Line, Transformed; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; DNA Fragmentation; Enzyme Inhibitors; Glutamic Acid; Glutathione Synthase; Hippocampus; Mice; Microscopy, Electron; Necrosis; Neurons; Oxidative Stress; Protein Kinase C; Protein Synthesis Inhibitors; RNA; Sulfones; Trypsin Inhibitors	1998
Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals. Neuroscience, 1999, Volume: 89, Issue:1 Topics: Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Chromans; Cycloheximide; DNA Fragmentation; Free Radicals; In Situ Nick-End Labeling; Iron; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Microscopy, Electron; Necrosis; Neurons; Potassium; Protein Synthesis Inhibitors; Zinc	1999
Tumor necrosis factor-alpha and ceramide induce cell death through different mechanisms in rat mesangial cells. The American journal of physiology, 1999, Volume: 276, Issue:3 Topics: Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cells, Cultured; Ceramides; Cycloheximide; Cytosol; Glomerular Mesangium; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Necrosis; NF-kappa B; Phospholipases A; Phospholipases A2; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha	1999
Induction of apoptosis and changes in nuclear G-actin are mediated by different pathways: the effect of inhibitors of protein and RNA synthesis in isolated rat hepatocytes. Toxicology and applied pharmacology, 1999, Apr-01, Volume: 156, Issue:1 Topics: Actins; Animals; Apoptosis; Caspases; Cell Nucleus; Cell Survival; Cycloheximide; Dactinomycin; Emetine; Liver; Male; Necrosis; Protein Synthesis Inhibitors; Puromycin; Rats; Rats, Wistar; RNA	1999
Apoptotic human lymphocytes have diminished CD4 and CD8 receptor expression. Cellular immunology, 1999, Apr-10, Volume: 193, Issue:1 Topics: Apoptosis; CD3 Complex; CD4 Antigens; CD8 Antigens; Cycloheximide; Etoposide; Humans; Lymphocytes; Necrosis; Transglutaminases	1999
Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress. Endocrinology, 2000, Volume: 141, Issue:2 Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cell Line; Cell Membrane; Cell Survival; Cells, Cultured; Cycloheximide; HeLa Cells; Humans; Iodide Peroxidase; Kinetics; Necrosis; Oxidative Stress; Phosphatidylserines; Potassium Iodide; Propylthiouracil; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Thyroid Gland; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2000
Potentiation of early necrotic death of glucose-starved pheochromocytoma 12 cells by nerve growth factor. Molecules and cells, 2000, Aug-31, Volume: 10, Issue:4 Topics: Animals; Calcium Channel Blockers; Cell Membrane; Cell Nucleus; Cycloheximide; DNA Fragmentation; Glucose; Kinetics; Microscopy, Confocal; Microscopy, Electron; Necrosis; Nerve Growth Factor; Neurons; Nifedipine; PC12 Cells; Protein Biosynthesis; Rats	2000
Necrosis of lung epithelial cells during infection with Mycobacterium tuberculosis is preceded by cell permeation. Infection and immunity, 2000, Volume: 68, Issue:11 Topics: Cells, Cultured; Cycloheximide; DNA; Epithelial Cells; Histones; Humans; L-Lactate Dehydrogenase; Lung; Mycobacterium tuberculosis; Necrosis; Permeability; Streptomycin; Tuberculosis	2000
Stroke. Neurobiology of disease, 2000, Volume: 7, Issue:5 Topics: Animals; Apoptosis; Cycloheximide; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Intracranial Embolism; Necrosis; Neuroprotective Agents; Plasminogen Activators; Spinal Cord Injuries; Stroke; Tissue Plasminogen Activator	2000
1,2-bis(2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid induces caspase-mediated apoptosis and reactive oxygen species-mediated necrosis in cultured cortical neurons. Journal of neurochemistry, 2001, Volume: 78, Issue:2 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Chelating Agents; Chromans; Cycloheximide; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Egtazic Acid; Fetus; Kinetics; Mice; Mice, Inbred ICR; Necrosis; Neocortex; Neuroglia; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Time Factors	2001
NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture. American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:4 Topics: Amino Acid Chloromethyl Ketones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Gastric Mucosa; Glucosamine; Guinea Pigs; Indomethacin; Male; Microscopy, Fluorescence; Necrosis; Protein Synthesis Inhibitors; Time Factors	2001
The mechanism of necrotic tissue removal in mouse liver following CCl4-induced injury. Journal of comparative pathology, 1979, Volume: 89, Issue:2 Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cycloheximide; Eosinophils; Liver; Male; Mice; Necrosis; Protease Inhibitors; Protein Biosynthesis	1979
Studies on the role of protein syntheis in cell injury by toxic agents: I. Effect of cycloheximide administration on several factors modulating carbon tetrachloride-induced liver necrosis. Toxicology and applied pharmacology, 1977, Volume: 41, Issue:2 Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytochrome Reductases; Drug Interactions; Lipid Metabolism; Liver; Liver Diseases; Male; Microsomes, Liver; Necrosis; Pentobarbital; Peroxides; Polyribosomes; Rats; Sleep; Time Factors	1977
Protective effects of an inhibitor of protein synthesis, cycloheximide, on bone marrow damage induced by cytosine arabinoside or nitrogen mustard. Laboratory investigation; a journal of technical methods and pathology, 1975, Volume: 33, Issue:5 Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Cycloheximide; Cytarabine; Erythropoiesis; Mechlorethamine; Necrosis; Protein Biosynthesis; Proteins; Rats	1975
An electron-microscope study of the mode of cell death induced by cancer-chemotherapeutic agents in populations of proliferating normal and neoplastic cells. The Journal of pathology, 1975, Volume: 116, Issue:3 Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Cell Count; Cell Nucleus; Cell Survival; Cilia; Cycloheximide; Cytarabine; Dactinomycin; Endoplasmic Reticulum; Epithelial Cells; Epithelium; Golgi Apparatus; Injections, Intraperitoneal; Intestinal Mucosa; Lysosomes; Male; Microscopy, Electron; Mitochondria; Mitomycins; Necrosis; Neutrophils; Rats; Ribosomes; Sarcoma 180; Time Factors	1975
Modification of the hepatotoxicity of D-galactosamine in the rat by cycloheximide. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 151, Issue:3 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cycloheximide; Galactosamine; Liver; Liver Diseases; Necrosis; Protein Biosynthesis; Rats; Triglycerides	1976
Induction of two different modes of cell death, apoptosis and necrosis, in rat liver after a single dose of thioacetamide. The American journal of pathology, 1991, Volume: 139, Issue:5 Topics: Alanine Transaminase; Animals; Cell Death; Chemical and Drug Induced Liver Injury; Cycloheximide; Dose-Response Relationship, Drug; Immunohistochemistry; Liver; Liver Regeneration; Male; Microscopy, Electron; Nafenopin; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors; Transglutaminases	1991
Central effects of cycloheximide alone and of its combination with T-2 toxin. Toxicology letters, 1991, Volume: 57, Issue:1 Topics: Animals; Brain; Cycloheximide; Drug Synergism; Injections; Lethal Dose 50; Liver; Male; Necrosis; Rats; T-2 Toxin	1991
The effects of endotoxin pretreatment on subsequent challenge of mice with cycloheximide and a small dose of endotoxin. Journal of comparative pathology, 1989, Volume: 101, Issue:4 Topics: Aminocaproic Acid; Ancrod; Animals; Capillaries; Cycloheximide; Endotoxins; Hydrocortisone; Kidney Cortex; Kidney Glomerulus; Male; Mice; Mice, Inbred CBA; Necrosis; Time Factors	1989
Uninterrupted protein synthesis is essential for survival in the early stages of carbon tetrachloride-induced hepatocellular necrosis in the mouse. Experientia, 1985, Oct-15, Volume: 41, Issue:10 Topics: Animals; Anti-Bacterial Agents; Carbon Tetrachloride Poisoning; Cycloheximide; Drug Synergism; Heparin; Intestines; Liver; Mice; Necrosis; Protein Biosynthesis; Time Factors	1985
Some observations on the acute histopathologic effects of cycloheximide in vivo. The American journal of pathology, 1971, Volume: 62, Issue:1 Topics: Adrenal Glands; Animals; Cycloheximide; Intestines; Lymph Nodes; Lymphoid Tissue; Mitosis; Necrosis; Protein Biosynthesis; Rats; Spleen; Thymus Gland	1971