cycloheximide has been researched along with Lung Neoplasms in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (19.40) | 18.7374 |
| 1990's | 28 (41.79) | 18.2507 |
| 2000's | 19 (28.36) | 29.6817 |
| 2010's | 5 (7.46) | 24.3611 |
| 2020's | 2 (2.99) | 2.80 |
| Authors | Studies |
|---|---|
| Han, AR; Kang, GY; Lee, YS; Seo, EK; Yoon, T | 1 |
| Ii, H; Kageyama, S; Kasahara, Y; Kawauchi, A; Nakata, S; Obika, S; Yamaguma, H | 1 |
| Liu, Q; Liu, X; Ma, M; Ren, D; Shen, T; Wang, S; Wang, X; Zheng, H | 1 |
| Andera, L; Kaminskyy, VO; Piskunova, T; Surova, OV; Tchevkina, EM; Zborovskaya, IB; Zhivotovsky, B | 1 |
| Chen, C; Cretoiu, SM; Shi, L; Wang, B; Wang, L; Wang, Q; Wang, X | 1 |
| Dong, M; Fan, D; Geng, P; Hou, P; Huang, B; Li, H; Li, Y; Li, Z; Liu, D; Lu, J; Ma, M; Mihretab, A; Wang, G; Yao, R; Zhang, Y | 1 |
| Andersen, JB; Black, CC; Dmitrovsky, E; Dragnev, K; Feng, Q; Galimberti, F; Guo, Y; Hassel, BA; Liu, X; Memoli, V; Sekula, D; Sempere, LF; Shah, SJ | 1 |
| Andrew, AS; Duell, EJ; Mason, RA; Memoli, V | 1 |
| Betta, PG; Biffo, S; Grosso, S; Patrone, M; Ranzato, E; Viarengo, A | 1 |
| Bergmann, MW; Gong, W; Holden, NS; King, EM; Newton, R; Rider, CF; Staples, KJ | 1 |
| Bradbury, ME; Nishi, K; Schnier, JB | 1 |
| Hooper, WC; Phillips, DJ; Talkington, DF; Yang, J | 1 |
| Fan, D; Wei, L; Yang, Y; Yao, L; You, H; Yu, Q; Zhang, X; Zhao, Y | 1 |
| Doctor, A; Gaston, B; Hunt, JF; Palmer, LA; Zaman, K | 1 |
| Doi, S; Fukuda, M; Kamihira, S; Kitazaki, T; Kohno, S; Nakamura, Y; Oka, M; Soda, H; Tsurutani, J; Yamada, Y | 1 |
| Dulloo, I; Sabapathy, K | 1 |
| Houtsmuller, AB; Mossink, MH; Scheffer, GL; Scheper, RJ; Schoester, M; Sonneveld, P; van Zon, A; Wiemer, EA | 1 |
| Dunlop, EA; Lappin, TR; Maxwell, AP | 1 |
| Boon-Unge, K; Govitrapong, P; Yu, Q; Zhou, A; Zhou, J; Zou, T | 1 |
| Takenaga, K | 2 |
| Bar-Eli, M; Gutman, M; Reich, R; Singh, RK | 1 |
| Moats-Staats, BM; Price, WA; Stiles, AD | 1 |
| Dohi, DF; Han, GR; Hong, WK; Kim, YH; Lotan, R; Nesbitt, JC; Oridate, N; Walsh, GL; Xu, XC; Zou, CP | 1 |
| Cook, JA; Fisher, J; Liebmann, J; Mitchell, JB; Teague, D | 1 |
| Abel, J; Döhr, O; Vogel, C | 1 |
| Lang, Z; Murlas, CG | 1 |
| Lenders, MH; Ramaekers, FC; Schutte, B; ten Velde, GP; Tinnemans, MM | 1 |
| Nørgaard, P; Poulsen, HS; Spang-Thomsen, M | 1 |
| Hirano, T; Hizuta, A; Orita, K; Tanaka, N | 1 |
| Fidler, IJ; Gutman, M; Llansa, N; Singh, RK | 1 |
| Bible, KC; Kaufmann, SH | 1 |
| Imoto, M; Masuda, N; Simizu, S; Takada, M; Umezawa, K | 1 |
| Lund, LR | 1 |
| Campau, S; Jasti, RK; Kalemkerian, GP; Mabry, M; Ou, X; Slusher, R | 1 |
| Das, KC; White, CW | 1 |
| Fushimi, K; Ichioka, M; Inase, N; Ishibashi, K; Marumo, F; Sasaki, S; Tanaka, M | 1 |
| Kamp, DW; Panos, RJ; Pollack, N; Sporn, PH; Wu, KI | 1 |
| Barnes, PJ; Bergmann, M; Kuitert, LM; Newton, R; Seybold, J | 1 |
| Barrett, JC; Deng, C; Solomon, G; Yin, Y | 1 |
| Idell, S; Shetty, S | 1 |
| Han, SK; Hwangbo, B; Kim, JY; Kim, YW; Lee, CT; Lee, S; Shim, YS; Yoo, CG | 1 |
| Horwitz, SB; Yang, CP | 1 |
| Amariglio, N; Domany, E; Getz, G; Givol, D; Jakob-Hirsch, J; Kaminski, N; Kannan, K; Kela, I; Rechavi, G | 1 |
| Hannun, YA; Kraveka, JM; Obeid, LM; Ogretmen, B; Schady, D; Usta, J | 1 |
| Bombick, DW; Desiderio, JG; Doolittle, DJ; Fields, WR; Putnam, KP | 1 |
| Harada, M; Ikeda, K; Ishimaru, F; Kiguchi, T; Kiura, K; Miyazono, T; Nakata, Y; Niiya, K; Shibakura, M; Shinagawa, K | 1 |
| Akiyama, H; Hosono, T; Kishi, S; Kurabayashi, M; Maeno, T; Maeno, Y; Nagai, R; Nakagawa, J; Sando, Y; Sato, M; Suga, T; Tanaka, T | 1 |
| Agostini, C; Muci, F | 1 |
| Dowling, MD; Young, CW | 1 |
| Baxter, G; Daniel-Issakani, S; Oto, E; Strulovici, B | 1 |
| Blasi, F; Danø, K; Ellis, V; Lund, LR; Rømer, J; Rønne, E | 1 |
| Lange-Carter, CA; Malkinson, AM | 1 |
| Burhans, MS; Clark, JC; Warner, BB; Wispé, JR | 1 |
| Clark, JC; O'Reilly, MA; Whitsett, JA | 1 |
| Kunos, G; Nakane, T; Seely, J; Stern, L; Szentendrei, T; Virmani, M | 1 |
| Chopra, H; Diglio, CA; Fligiel, SE; Hatfield, JS; Honn, KV; Nelson, KK; Taylor, JD | 1 |
| Broadus, AE; Ikeda, K; Lu, C; Mangin, M; Weir, EC | 1 |
| Hayaishi, O; Takai, K; Yasui, H; Yoshida, R | 1 |
| Chaloupková, A; Krepela, E; Rasnick, D; Urbanec, P; Veselý, P; Vicar, J; Zicha, D | 1 |
| Saksela, K | 1 |
| Findlay, DM; Martin, TJ | 1 |
| Kang, AH; Keski-Oja, J; Loskutoff, DJ; Moses, HL; Postlethwaite, AE; Raghow, R; Sawdey, M | 1 |
| Becker, M; Moczar, E; Moczar, M; Poupon, MF | 1 |
| Ben-Ze'ev, A; Raz, A | 1 |
| Matthews, EK; Pearlmutter, F; Saffran, M | 1 |
| Weisburger, EK; Weisburger, JH; Yamamoto, RS | 1 |
1 review(s) available for cycloheximide and Lung Neoplasms
| Article | Year |
|---|---|
Analysis of the response to ACTH by rat adrenal in a flowing system.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Automation; Carcinoma; Corticosterone; Cyclic AMP; Cycloheximide; Fluorescence; Fluorometry; Lung Neoplasms; Membrane Potentials; Methods; Pituitary Gland; Rats; Time Factors; Tissue Extracts; Vasopressins | 1971 |
66 other study(ies) available for cycloheximide and Lung Neoplasms
| Article | Year |
|---|---|
2,4-Bis(4-hydroxybenzyl)phenol inhibits heat shock transcription factor 1 and sensitizes lung cancer cells to conventional anticancer modalities.
Topics: Apoptosis; Benzhydryl Compounds; Caspase 3; DNA-Binding Proteins; Heat Shock Transcription Factors; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Lung Neoplasms; Molecular Structure; Phenols; Polymerase Chain Reaction; Transcription Factors | 2014 |
Administration of Gapmer-type Antisense Oligonucleotides Targeting γ-Glutamylcyclotransferase Suppresses the Growth of A549 Lung Cancer Xenografts.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle Proteins; Cell Proliferation; Cycloheximide; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice, SCID; Oligonucleotides, Antisense; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2022 |
Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation.
Topics: Animals; Apoptosis; Autophagosomes; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Chromatin; Cycloheximide; Endoplasmic Reticulum Stress; Flavonoids; Humans; Lung Neoplasms; Phosphatidylserines; Protein Synthesis Inhibitors; Zebrafish | 2022 |
Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling.
Topics: Apoptosis; Calcium; Calmodulin; Carcinoma, Non-Small-Cell Lung; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Cycloheximide; Humans; Lung Neoplasms; Protein Synthesis Inhibitors; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2013 |
Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells.
Topics: Apoptosis; Betacellulin; Cell Count; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cycloheximide; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lipopolysaccharides; Lung Neoplasms; Models, Biological; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Quinazolines; Receptor Protein-Tyrosine Kinases; Tumor Necrosis Factor-alpha | 2014 |
The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer.
Topics: Animals; Breast Neoplasms; Cadherins; CDC2 Protein Kinase; Cell Line, Tumor; Cell Movement; Cycloheximide; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Leupeptins; Lung Neoplasms; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Proteasome Endopeptidase Complex; Protein Binding; RNA, Long Noncoding; Ubiquitin | 2017 |
UBE1L causes lung cancer growth suppression by targeting cyclin D1.
Topics: Anticarcinogenic Agents; Bexarotene; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cycloheximide; Cytokines; Humans; Ki-67 Antigen; Lung Neoplasms; Models, Biological; Plasmids; Retinoid X Receptors; Tetrahydronaphthalenes; Ubiquitin-Activating Enzymes; Ubiquitins | 2008 |
Arsenic activates EGFR pathway signaling in the lung.
Topics: Adult; Aged; Amphiregulin; Analysis of Variance; Arsenic; Arsenites; Biomarkers; Bronchi; Cells, Cultured; Cyclin D1; Cycloheximide; EGF Family of Proteins; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Erlotinib Hydrochloride; Gene Expression; Glycoproteins; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lung; Lung Neoplasms; Middle Aged; Nails; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium Compounds | 2009 |
Spreading of mesothelioma cells is rapamycin-sensitive and requires continuing translation.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Culture Media, Serum-Free; Cycloheximide; Fibronectins; Humans; Lung Neoplasms; Mechanistic Target of Rapamycin Complex 1; Mesothelioma; Multiprotein Complexes; Neoplasm Metastasis; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Sirolimus; TOR Serine-Threonine Kinases; Transcription Factors | 2009 |
Glucocorticoids inhibit IL-1beta-induced GM-CSF expression at multiple levels: roles for the ERK pathway and repression by MKP-1.
Topics: Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Enzyme Repression; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1beta; Lung Neoplasms; Phosphorylation; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Cell shape change precedes staurosporine-induced stabilization and accumulation of p27kip1.
Topics: Cell Cycle; Cell Cycle Proteins; Cell Size; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cycloheximide; Cysteine Endopeptidases; Cytochalasin D; Cytoskeleton; Diacetyl; Enzyme Inhibitors; Female; Flow Cytometry; Humans; Lung Neoplasms; Microscopy, Confocal; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Proteins; Uterine Cervical Neoplasms | 2002 |
Interleukin-1beta responses to Mycoplasma pneumoniae infection are cell-type specific.
Topics: Bacterial Adhesion; Carcinoma; Caspase 1; Caspase Inhibitors; Cycloheximide; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Lung Neoplasms; Mycoplasma pneumoniae; Neoplasm Proteins; Organ Specificity; Protein Synthesis Inhibitors; RNA, Messenger; Tumor Cells, Cultured; U937 Cells | 2003 |
Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Cell Line, Tumor; Cell Survival; Chromones; Cycloheximide; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; Lung Neoplasms; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction | 2004 |
Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1.
Topics: Animals; Cell Line; Cell Line, Tumor; Culture Media, Serum-Free; Cycloheximide; Cystic Fibrosis Transmembrane Conductance Regulator; Dactinomycin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drosophila melanogaster; Gene Expression Regulation; Humans; Isoxazoles; Lung Neoplasms; Plicamycin; Protein Binding; Pulmonary Alveoli; Recombinant Fusion Proteins; RNA, Messenger; S-Nitrosoglutathione; Signal Transduction; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors; Transcription, Genetic; Transfection | 2004 |
The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Small Cell; Caspase 3; Caspases; Cell Line, Tumor; Cycloheximide; Depsipeptides; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lung Neoplasms; Mitochondria; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger | 2004 |
Transactivation-dependent and -independent regulation of p73 stability.
Topics: Base Sequence; Cell Line, Tumor; Cloning, Molecular; Cycloheximide; DNA Primers; DNA-Binding Proteins; Genes, Reporter; Genes, Tumor Suppressor; Homeostasis; Humans; Kinetics; Luciferases; Lung Neoplasms; Nuclear Proteins; Sequence Deletion; Transcriptional Activation; Tumor Protein p73; Tumor Suppressor Proteins | 2005 |
Vault mobility depends in part on microtubules and vaults can be recruited to the nuclear envelope.
Topics: Active Transport, Cell Nucleus; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Nucleus; Cycloheximide; Cytoplasm; Fibroblasts; Fluorescence Recovery After Photobleaching; Green Fluorescent Proteins; Humans; Lung Neoplasms; Microtubules; Nuclear Envelope; Protein Binding; Protein Synthesis Inhibitors; Proteolipids; Proton-Translocating ATPases; Tubulin; Tumor Cells, Cultured; Vacuolar Proton-Translocating ATPases; Vault Ribonucleoprotein Particles | 2006 |
Impaired downregulation following erythropoietin receptor activation in non-small cell lung carcinoma.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cycloheximide; Down-Regulation; Erythropoietin; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lysosomes; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Processing, Post-Translational; Receptors, Erythropoietin; Recombinant Proteins; RNA, Messenger; Suppressor of Cytokine Signaling Proteins; Ubiquitins | 2007 |
Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.
Topics: Alternative Splicing; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Down-Regulation; Emetine; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Marine Toxins; Okadaic Acid; Oxazoles; Prostatic Neoplasms; Protein Phosphatase 1; Protein Phosphatase 2; Up-Regulation; Uterine Cervical Neoplasms | 2007 |
Enhancement of lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells by treatment with highly polar compounds.
Topics: Animals; Carcinoma; Cathepsins; Cell Adhesion; Cycloheximide; Dimethyl Sulfoxide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Plasminogen Activators; Structure-Activity Relationship; Trypsin | 1984 |
Ultraviolet B irradiation promotes tumorigenic and metastatic properties in primary cutaneous melanoma via induction of interleukin 8.
Topics: Animals; Carrier Proteins; Collagenases; Cyclin-Dependent Kinase Inhibitor p16; Cycloheximide; Dose-Response Relationship, Radiation; Gene Expression Regulation, Neoplastic; Genes, p53; In Vitro Techniques; Interleukin-8; Lung Neoplasms; Male; Matrix Metalloproteinase 9; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; RNA, Messenger; Skin Neoplasms; Tumor Cells, Cultured; Ultraviolet Rays | 1995 |
Insulin-like growth factor-I (IGF-I) regulates IGFBP-3 and IGFBP-4 by multiple mechanisms in A549 human adenocarcinoma cells.
Topics: Adenocarcinoma; Base Sequence; Cell Count; Cell Division; Culture Media, Conditioned; Cycloheximide; DNA; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lung; Lung Neoplasms; Molecular Sequence Data; Protein Synthesis Inhibitors; Receptor, IGF Type 1; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Retinoid refractoriness occurs during lung carcinogenesis despite functional retinoid receptors.
Topics: Animals; Base Sequence; Bronchi; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Division; Cycloheximide; Dactinomycin; Epithelium; Humans; Keratolytic Agents; Lung Neoplasms; Mice; Molecular Sequence Data; Precancerous Conditions; Protein Synthesis Inhibitors; Rats; Receptors, Retinoic Acid; Tretinoin; Tumor Cells, Cultured | 1995 |
Cycloheximide inhibits the cytotoxicity of paclitaxel (Taxol).
Topics: Adenocarcinoma; Breast Neoplasms; Cell Cycle; Cell Death; Cycloheximide; DNA, Neoplasm; Drug Interactions; Flow Cytometry; Humans; Lung Neoplasms; Mitotic Index; Neoplasm Proteins; Paclitaxel; Tumor Cells, Cultured | 1994 |
Transforming growth factor-beta 1 inhibits TCDD-induced cytochrome P450IA1 expression in human lung cancer A549 cells.
Topics: Cycloheximide; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Lung Neoplasms; Oxidoreductases; Polychlorinated Dibenzodioxins; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured | 1994 |
Dexamethasone increases airway epithelial cell neutral endopeptidase by enhancing transcription and new protein synthesis.
Topics: Carcinoma, Squamous Cell; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Epithelium; Humans; Lung; Lung Neoplasms; Neprilysin; Protein Biosynthesis; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis.
Topics: Antigens, Nuclear; Apoptosis; Cycloheximide; Cytoskeletal Proteins; DNA; Genetic Techniques; Humans; Keratins; Lung Neoplasms; Nuclear Proteins; Staining and Labeling; Tumor Cells, Cultured | 1995 |
Expression and autoregulation of transforming growth factor beta receptor mRNA in small-cell lung cancer cell lines.
Topics: Activin Receptors, Type I; Blotting, Northern; Carcinoma, Small Cell; Cell Line; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Protein Serine-Threonine Kinases; Proteoglycans; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured | 1996 |
Enhancement of experimental metastasis by gamma-interferon in a murine adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antibodies; Cell Survival; Colonic Neoplasms; Cycloheximide; G(M1) Ganglioside; Interferon-gamma; Killer Cells, Lymphokine-Activated; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Osmotic Fragility; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Interferon-beta prevents the upregulation of interleukin-8 expression in human melanoma cells.
Topics: Animals; Cycloheximide; Dactinomycin; Female; Gene Expression Regulation, Neoplastic; Humans; Interferon alpha-2; Interferon-alpha; Interferon-beta; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-8; Lung Neoplasms; Lymphatic Metastasis; Melanoma; Mice; Mice, Nude; Middle Aged; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells.
Topics: Antineoplastic Agents; Aphidicolin; Apoptosis; Cell Cycle; Cell Survival; Cycloheximide; Flavonoids; Humans; Lung Neoplasms; Piperidines; Tumor Cells, Cultured | 1996 |
Involvement of hydrogen peroxide production in erbstatin-induced apoptosis in human small cell lung carcinoma cells.
Topics: Antioxidants; Apoptosis; Carcinoma, Small Cell; Cycloheximide; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Hydroquinones; Lung Neoplasms; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1996 |
Expression of urokinase-type plasminogen activator, its receptor and type-1 plasminogen activator inhibitor is differently regulated by inhibitors of protein synthesis in human cancer cell lines.
Topics: Anisomycin; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Emetine; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Lung Neoplasms; Protein Synthesis Inhibitors; Puromycin; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Rhabdomyosarcoma; RNA, Messenger; RNA, Neoplasm; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1996 |
Mechanism of all-trans-retinoic acid-mediated L-myc gene regulation in small cell lung cancer.
Topics: Carcinoma, Small Cell; Cell Division; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-myc; Receptors, Retinoic Acid; RNA, Messenger; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1996 |
Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.
Topics: Adenocarcinoma; Antineoplastic Agents; Binding, Competitive; Cell Nucleus; Cycloheximide; Dactinomycin; Daunorubicin; Dexamethasone; Doxorubicin; Enzyme Inhibitors; Humans; Kinetics; Lung Neoplasms; NF-kappa B; Oligodeoxyribonucleotides; Paclitaxel; Protein Kinase C; Transcription Factors; Tumor Cells, Cultured; Vincristine | 1997 |
Induction of aquaporin 3 by corticosteroid in a human airway epithelial cell line.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aquaporin 3; Aquaporins; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Kinetics; Lung Neoplasms; Mercaptoethanol; Mercuric Chloride; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Keratinocyte growth factor promotes alveolar epithelial cell DNA repair after H2O2 exposure.
Topics: Animals; Aphidicolin; Cell Death; Cycloheximide; Dactinomycin; DNA Damage; DNA Repair; Enzyme Inhibitors; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Genistein; Growth Substances; Humans; Hydrogen Peroxide; Kinetics; Lung Neoplasms; Naphthalenes; Protein Kinase C; Protein-Tyrosine Kinases; Pulmonary Alveoli; Rats; Staurosporine; Tumor Cells, Cultured | 1998 |
Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA.
Topics: Cycloheximide; Cyclooxygenase 2; Dactinomycin; Dexamethasone; Dinoprostone; Enzyme Induction; Hormone Antagonists; Humans; Interleukin-1; Isoenzymes; Kinetics; Lung; Lung Neoplasms; Membrane Proteins; Mifepristone; Prostaglandin-Endoperoxide Synthases; Repetitive Sequences, Nucleic Acid; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Differential regulation of p21 by p53 and Rb in cellular response to oxidative stress.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Cell Line; Chloramphenicol O-Acetyltransferase; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Enzyme Inhibitors; Estradiol; Fibroblasts; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Lung Neoplasms; Mice; Mice, Knockout; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Retinoblastoma Protein; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Posttranscriptional regulation of urokinase receptor gene expression in human lung carcinoma and mesothelioma cells in vitro.
Topics: Anisomycin; Carcinoma; Cell Movement; Cycloheximide; DNA; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mesothelioma; Pleura; Protein Biosynthesis; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA Processing, Post-Transcriptional; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1999 |
NF-kappaB activation is related to the resistance of lung cancer cells to TNF-alpha-induced apoptosis.
Topics: Adenoviridae; Apoptosis; Cycloheximide; Cysteine Endopeptidases; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; I-kappa B Proteins; Lung Neoplasms; Multienzyme Complexes; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Taxol mediates serine phosphorylation of the 66-kDa Shc isoform.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antineoplastic Agents, Phytogenic; Carcinoma; Cyanogen Bromide; Cycloheximide; Drug Interactions; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Flavonoids; Humans; Lung Neoplasms; MAP Kinase Kinase Kinases; Microtubules; Paclitaxel; Peptide Fragments; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins c-raf; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tumor Cells, Cultured; Tyrosine | 2000 |
DNA microarrays identification of primary and secondary target genes regulated by p53.
Topics: Animals; Cluster Analysis; Cycloheximide; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line.
Topics: Adenocarcinoma; Ceramides; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, Reporter; Half-Life; Humans; Luciferases; Lung Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telomerase; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Ubiquitins | 2001 |
Quantification of changes in c-myc mRNA levels in normal human bronchial epithelial (NHBE) and lung adenocarcinoma (A549) cells following chemical treatment.
Topics: Actins; Adenocarcinoma; Adult; Bronchi; Carcinogens; Child; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Lung Neoplasms; Male; Methylnitronitrosoguanidine; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2001 |
Induction of urokinase-type plasminogen activator by the anthracycline antibiotic in human RC-K8 lymphoma and H69 lung-carcinoma cells.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Antioxidants; Blotting, Northern; Cell Nucleus; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Humans; Lung Neoplasms; Lymphoma; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; RNA, Messenger; Time Factors; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2001 |
Stimulation of vascular endothelial growth factor gene transcription by all trans retinoic acid through Sp1 and Sp3 sites in human bronchioloalveolar carcinoma cells.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Binding Sites; Cycloheximide; DNA-Binding Proteins; Endothelial Growth Factors; Enzyme Inhibitors; Genes, Reporter; Genistein; Humans; Lung Neoplasms; Lymphokines; Mice; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Effects of cycloheximide on protein synthesis in human lung tumors, regenerating rat liver and hepatomas.
Topics: Animals; Cycloheximide; Dose-Response Relationship, Drug; Kidney; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Lung Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis | 1979 |
Antipyretic effect of cycloheximide, and inhibitor of protein synthesis, in patients with Hodgkin's disease or other malignant neoplasms.
Topics: Bacterial Infections; Cycloheximide; Female; Fever; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphatic Diseases; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Muramidase; Neoplasm Proteins; Neoplasms; Nitrogen; Ribonucleases; Uterine Cervical Neoplasms | 1975 |
Constitutive presence of a catalytic fragment of protein kinase C epsilon in a small cell lung carcinoma cell line.
Topics: Amino Acid Sequence; Antibodies; Binding Sites; Brain; Carcinoma, Small Cell; Cell Line; Cycloheximide; Cytosol; Humans; Immunoblotting; Isoenzymes; Kinetics; Lung Neoplasms; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptide Mapping; Peptides; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Urokinase-receptor biosynthesis, mRNA level and gene transcription are increased by transforming growth factor beta 1 in human A549 lung carcinoma cells.
Topics: Blotting, Northern; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Humans; Lung Neoplasms; Plasminogen Activators; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1991 |
Differential regulation of the stability of cyclic AMP-dependent protein kinase messenger RNA in normal versus neoplastic mouse lung epithelial cells.
Topics: Animals; Blotting, Northern; Cycloheximide; Dichlororibofuranosylbenzimidazole; Epithelium; Gene Expression; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Protein Kinases; RNA, Messenger; RNA, Neoplasm | 1991 |
Tumor necrosis factor-alpha increases Mn-SOD expression: protection against oxidant injury.
Topics: Actins; Adenocarcinoma; Cell Line; Cell Survival; Cycloheximide; Dactinomycin; Gene Expression; Humans; Isoenzymes; Kinetics; Lung Neoplasms; Paraquat; Recombinant Proteins; RNA, Messenger; Superoxide Dismutase; Superoxides; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1991 |
Glucocorticoid enhances pulmonary surfactant protein B gene transcription.
Topics: Adenocarcinoma; Cell Line; Cell Nucleus; Cloning, Molecular; Cycloheximide; Dactinomycin; Dexamethasone; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Lung Neoplasms; Nucleic Acid Hybridization; Proteolipids; Pulmonary Surfactants; Puromycin; RNA, Messenger; Transcription, Genetic | 1991 |
Effects of IL-1 and cortisol on beta-adrenergic receptors, cell proliferation, and differentiation in cultured human A549 lung tumor cells.
Topics: Cell Adhesion; Cell Differentiation; Cell Division; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Endocytosis; Growth Inhibitors; Humans; Hydrocortisone; Interleukin-1; Isoproterenol; Lung Neoplasms; Receptors, Adrenergic, beta; Receptors, Glucocorticoid; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 1990 |
An in vivo study of the role of the tumor cell cytoskeleton in tumor cell-platelet-endothelial cell interactions.
Topics: Animals; Blood Platelets; Cell Communication; Colchicine; Cycloheximide; Cytochalasin D; Cytoskeleton; Endothelium; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Microscopy, Electron; Neoplasm Metastasis; Platelet Aggregation | 1990 |
Regulation of parathyroid hormone-related peptide gene expression by cycloheximide.
Topics: Actins; Animals; Cycloheximide; Exons; Gene Expression Regulation; Humans; Kidney Neoplasms; Leydig Cell Tumor; Lung Neoplasms; Nucleic Acid Hybridization; Osteosarcoma; Parathyroid Hormone-Related Protein; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Proteins; Rats; RNA Splicing; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: its possible occurrence in cancer patients.
Topics: Cycloheximide; Dactinomycin; Enzyme Induction; In Vitro Techniques; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferons; Liver; Lung; Lung Neoplasms; Oxygenases; Pneumothorax; Tryptophan; Tryptophan Oxygenase | 1986 |
Cathepsin B in cells of two rat sarcomas with different rates of spontaneous metastasis.
Topics: Animals; Cathepsin B; Cathepsin H; Cathepsins; Clone Cells; Culture Media; Cycloheximide; Cysteine Endopeptidases; Cytoplasm; Histocytochemistry; Hydrogen-Ion Concentration; Lung Neoplasms; Neoplasm Metastasis; Rats; Rats, Inbred Lew; Sarcoma, Experimental; Tumor Cells, Cultured | 1989 |
Expression of the L-myc gene is under positive control by short-lived proteins.
Topics: Carcinoma, Small Cell; Cycloheximide; Dactinomycin; DNA, Neoplasm; Gene Amplification; Gene Expression Regulation; Humans; Lung Neoplasms; Oncogenes; Proto-Oncogene Proteins; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1987 |
Kinetics of calcitonin receptor internalization in lung cancer (BEN) and osteogenic sarcoma (UMR 106-06) cells.
Topics: Animals; Bone Neoplasms; Calcitonin; Carcinoma, Squamous Cell; Cycloheximide; Endocytosis; Hydrogen-Ion Concentration; Lung Neoplasms; Osteosarcoma; Receptors, Calcitonin; Receptors, Cell Surface; Salmon; Temperature; Tumor Cells, Cultured | 1986 |
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells.
Topics: Actins; Adenocarcinoma; Cycloheximide; Extracellular Matrix; Fibroblasts; Fibronectins; Gene Expression Regulation; Glycoproteins; Humans; Immunosorbent Techniques; Lung; Lung Neoplasms; Nucleic Acid Hybridization; Peptides; Plasminogen Activators; Plasminogen Inactivators; Procollagen; RNA, Messenger; Transforming Growth Factors; Tumor Cells, Cultured | 1988 |
Solubilization and degradation of extracellular matrix by various metastatic cell lines derived from a rat rhabdomyosarcoma.
Topics: Animals; Cell Line; Cycloheximide; Extracellular Matrix; Female; Glycoproteins; Glycosaminoglycans; Lung Neoplasms; Molecular Weight; Neoplasm Metastasis; Proteoglycans; Rats; Rhabdomyosarcoma; Solubility | 1986 |
Effect of butyric acid on lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cathepsins; Cell Adhesion; Cycloheximide; Endothelium; Fatty Acids; Histones; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; Phenotype; Plasminogen Activators; Structure-Activity Relationship | 1986 |
Relationship between the organization and synthesis of vimentin and the metastatic capability of B16 melanoma cells.
Topics: Animals; Cells, Cultured; Cycloheximide; Cytoskeleton; Humans; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; RNA, Messenger; Vimentin | 1985 |
Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.
Topics: Animals; Body Weight; Chlordan; Cycloheximide; Dactinomycin; Flavonoids; Hematocrit; Lung Neoplasms; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Organ Size; Phenobarbital; Phenothiazines; Proadifen; Puromycin; Urethane | 1971 |