cycloheximide has been researched along with Hepatocellular Carcinoma in 205 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 99 (48.29) | 18.7374 |
| 1990's | 65 (31.71) | 18.2507 |
| 2000's | 31 (15.12) | 29.6817 |
| 2010's | 8 (3.90) | 24.3611 |
| 2020's | 2 (0.98) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, S; Im, E; Jung, JH; Kim, JH; Kim, S; Kim, SH; Lee, HJ; Sim, DY | 1 |
| Cho, SS; Ki, SH; Kim, KM | 1 |
| Cao, H; Ren, SN; Tian, XF; Zang, HL | 1 |
| Ao, JY; Cai, H; Cao, MQ; Chai, ZT; Kong, LQ; Li, KS; Li, XL; Shi, WK; Sun, HC; Wang, CH; Ye, BG; Zhang, SZ; Zhang, YY; Zhu, XD | 1 |
| Chao, TI; Chen, KF; Chen, LJ; Chen, YL; Chu, PY; Hsieh, FS; Huang, CY; Hung, MH; Shih, CT; Tsai, MH | 1 |
| Baccino, FM; Bonelli, G; Costelli, P; Khadjavi, A; Minero, VG | 1 |
| Corn, DJ; Kuang, Y; Lee, Z; Tian, H; Wang, F | 1 |
| Cao, EH; Liang, XQ; Liu, XM; Song, Y; Tang, RJ; Xiong, XF | 1 |
| Chen, WJ; Cheng, WL; Chien, LF; Huang, YH; Liao, CH; Liao, CJ; Lin, KH; Lu, YH; Tsai, MM; Wu, SM; Yeh, CT | 1 |
| Cao, M; Liu, C; Liu, JJ; Nelson, DR; Zhao, X; Zhu, H | 1 |
| Autelli, R; Baccino, FM; Bonelli, G; Brunk, UT; Casas, J; Fabriàs, G; Ghidoni, R; Sala, G; Ullio, C | 1 |
| Bradham, CA; Brenner, DA; Kubicka, S; Liedtke, C; Manns, MP; Plümpe, J; Trautwein, C | 1 |
| Gómez, N; Itarte, E; Llorens, F; Miro, FA; Plana, M; Roher, N | 1 |
| Bae, MA; Song, BJ | 1 |
| Cai, M; Gu, JX; Hu, Y; Zhang, S; Zhang, SW | 1 |
| Deguchi, M; Fujikawa, K; Inoue, H; Kawakita, T; Murata, K; Nakano, T; Ohmori, S; Okano, H; Sakai, T; Shiraki, K; Sugimoto, K; Yamanaka, T | 1 |
| Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M | 1 |
| Araki, E; Hirashima, Y; Igata, M; Kahn, CR; Kodama, S; Toyonaga, T; Tsuruzoe, K; Ueki, K | 1 |
| Hsu, JM; Huang, CY; Lee, YC; Yu, CT | 1 |
| Bulla, GA; Kraus, DM; Schmitz, EK | 1 |
| Borriello, A; Criniti, V; Cucciolla, V; Della Ragione, F; Gasparini, P; Giordani, L; Indaco, S; Iolascon, A; Maiorano, N; Moretti, A; Servedio, V; Volinia, S | 1 |
| Chen, CY; Chen, SL; Huang, YH; Lin, KH; Shen, JJ; Shih, CH; Wang, CS; Yang, RC; Yen, CC | 1 |
| Fujita, T; Tanaka, K; Yamamoto, A | 1 |
| El-Kadi, AO; Korashy, HM | 1 |
| Hirano, K; Ikegami, C; Koseki, M; Maruyama, T; Masuda, D; Matsuura, F; Nakagawa-Toyama, Y; Shimomura, I; Tsujii, K; Ueda, Y; Yamashita, S; Zhang, Z | 1 |
| Yeh, CT; Yen, GC | 1 |
| Caruso, JA; Joiakim, A; Mathieu, PA; Reiners, JJ; Zhang, H | 1 |
| Balakrishnan, K; De Maio, A | 1 |
| Blaho, JA; Morton, ER | 1 |
| Gu, J; Jiang, J; Liu, D; Shen, J; Wei, Y; Zhou, J; Zhou, L | 1 |
| Bulla, GA; Ellis, J; Kraus, DM; Reidy, MR; Schmitz, EA | 1 |
| Proud, CG; Wang, X | 1 |
| Bogdanová, K; Cervenková, K; Poczatková, H; Riegrová, D; Rypka, M; Uherková, L; Veselý, J | 1 |
| Block, C; Diesterhaft, M; Granner, D; Hargrove, J; Noguchi, T; Olson, P; Seifert, S | 1 |
| DiSorbo, DM; Litwack, G; Moriarity, DM; Savage, CR | 1 |
| Fridovich, SE; Lodish, HF; Schwartz, AL | 1 |
| Merchant, B; Mitamura, K; Purcell, RH; Tang, ZY; Wen, YM | 1 |
| Bauer, C; Gassmann, M; Marti, HH; Rolfs, A; Wenger, RH | 1 |
| Balsano, C; Chirillo, P; Costanzo, A; De Petrillo, G; Ianni, A; Ilari, I; Levrero, M; Natoli, G | 1 |
| Jeong, SY; Kim, HS; Kim, IK; Lee, JH | 1 |
| Adlercreutz, H; Carson, M; Loukovaara, M | 1 |
| Gabel, CA; Laliberte, RE; McNiff, PA; Pazoles, CJ; Svensson, L | 1 |
| Floren, CH; Hultberg, B; Isaksson, A; Jensen, E | 1 |
| Carr, BI; Inagaki, M; Wang, Z | 1 |
| Fardel, O; Glaise, D; Guillouzo, A; Lecureur, V; Loyer, P | 1 |
| Bereziat, G; Janvier, B; Loriette, C; Mangeney-Andreani, M; Vandenbrouck, Y | 1 |
| Miyabo, S; Nakai, T; Oida, K; Shimada, A; Suzuki, J; Takahashi, S; Tamai, T | 1 |
| Liu, MC; Sakakibara, Y; Suiko, M | 1 |
| Ebert, BL; Firth, JD; Pugh, CW; Ratcliffe, PJ | 1 |
| Ikura, K; Sasaki, R; Suto, N | 1 |
| Barlow, JW; Blok, RB; Cowen, NL; Crowe, TC; Raggatt, LE; Stockigt, JR; Topliss, DJ | 1 |
| Agrawal, KC; George, WJ; Gogu, SR; Hilburger, CL; Rider, BJ; White, LE | 1 |
| Bergelson, S; Daniel, V; Pinkus, R | 1 |
| Ashwell, G; Morell, AG; Stockert, RJ; Weiss, P | 1 |
| Florén, CH; Liao, W | 1 |
| Berg, DT; Calnek, DS; Grinnell, BW | 1 |
| Kato, M; Suzuki, A | 1 |
| Lee, KY; Lee, SK | 1 |
| Herenyiova, M; Look, KY; Prajda, N; Shen, F; Singhal, RL; Weber, G; Yang, H; Yeh, YA | 1 |
| Kim, HS; Kim, IK; Lee, JH | 1 |
| Ahn, DS; Jo, BH; Kim, DG; You, KR | 1 |
| Abdullah, N; Fantus, IG; Tsiani, E | 1 |
| Alvarez, L; Gil, B; Mato, JM; Pajares, MA | 1 |
| Martini, G; Parrella, A; Rosa, G; Salzano, S; Ursini, MV | 1 |
| Davies, PH; Franklyn, JA; Sheppard, MC | 1 |
| Chin, K; Esumi, H; Kurashima, Y; Ogura, T; Tajiri, H; Yoshida, S | 1 |
| Higashiyama, S; Ito, N; Kawata, S; Kiso, S; Matsuzawa, Y; Nakagawa, T; Tamura, S; Taniguchi, N; Tsushima, H | 1 |
| Danno, S; Fujita, J; Higashitsuji, H; Itoh, K; Matsuda, T; Nishiyama, H; Xue, JH; Yokoi, H | 1 |
| Ingelman-Sundberg, M; Zhukov, A | 1 |
| Bradham, C; Brenner, DA; Czaja, MJ; Xu, Y | 1 |
| Asami, K; Kimura, K; Yamamoto, M | 1 |
| Harada, N; Hatano, O | 1 |
| Balsalobre, A; Damiola, F; Schibler, U | 1 |
| Jessen, KA; Satre, MA | 1 |
| Fung, M; Minta, JO; Paramaswara, B | 1 |
| Daghman, NA; Lappin, TR; Maxwell, AP; McHale, CM; Price, S; Savage, GM; Winter, PC | 1 |
| Lee, C; Prokipcak, RD; Raouf, A | 1 |
| Bell, A; Dhawan, P; Golden, C; Kumar, A; Mehta, KD | 1 |
| Fitch, CA; Levenson, CW; Narayanan, VS; Song, Y; Yeiser, EC | 1 |
| Dumoulin, FL; Sauerbruch, T; Söhne, J; Spengler, U; vsn dem Bussche, A | 1 |
| Fung, M; Minta, J | 1 |
| de Crombrugghe, B; Kim, IS; Kim, MS; Lee, BH; Park, RW; Rhew, JH | 1 |
| Bácsy, E; Bander, E; Buday, L; Faragó, A; Farkas, G; Sipeki, S; Ways, DK | 1 |
| Beile, B; Leibold, A; Leube, RE; Thomas, S; Wilhelm, U; Windoffer, R | 1 |
| Bringuier, AF; Feldmann, G; Lamboley, C | 1 |
| Hu , R; Liu , W; Liu , X; Zhai , Q | 1 |
| Brown, PO; Frueh, FW; Hayashibara, KC; Whitlock, JP | 1 |
| Fang, Y; Jin, J; Wang, L; Zha, X | 1 |
| Li, J; Wang, Z; Zheng, R | 1 |
| Ahn, YS; Hong, SS; Kim, CH; Kim, H; Kim, K; Kim, SJ; Park, JH; Seong, YR; Shin, EC | 1 |
| Kenney, FT; Lee, KL; Stiles, CD | 2 |
| Freikopf, A; Kulka, RG | 1 |
| Su, JL; Wicks, WD | 1 |
| Cannelakis, ZN; Theoharides, TC | 1 |
| Borsos, T; Boyle, MD; Ohanian, SH | 1 |
| Grimm, J; Manchester, KL | 1 |
| Colten, HR; Strunk, RC; Tashjian, AH | 1 |
| Chalkley, R; Granner, DK; Jackson, V; Shires, A | 1 |
| Elias-Bishko, S; Epstein, D; Hershko, A | 1 |
| McClure, D; Miller, MR; Shiman, R | 2 |
| Canellakis, ES; Fong, WF; Heller, JS | 1 |
| Canellakis, ZN; Theoharides, TC | 1 |
| Ballard, FJ; Knowles, SE | 1 |
| Busch, H; Pike, LM; Raj, NB; Ro-Choi, TS | 1 |
| Roth, JJ; Roth, JS | 1 |
| Mamont, PS; McCann, PP; Tardif, C | 1 |
| Duchesne, MC; Mamont, PS; McCann, PP; Tardif, C | 1 |
| Arbuzov, VA | 1 |
| Ballard, FJ | 1 |
| Liu, CK; Schmied, R; Waxman, S | 1 |
| Fan, WJ; Ivarie, RD; Tomkins, GM | 1 |
| Kimura, H; Murad, F | 1 |
| Angervo, M | 1 |
| Chou, CK; Hsu, SL; Lin, YF | 1 |
| Borén, J; Graham, L; Olofsson, SO; Scott, J; Wettesten, M; White, A | 1 |
| Hug, V; Levy, JR | 1 |
| Heinrich, PC; Müllberg, J; Rose-John, S; Schooltink, H; Stoyan, T | 1 |
| Goldberg, DM; Hahn, SE; Parkes, JG | 1 |
| Fujita, H; Kappas, A; Mitani, K; Sassa, S | 2 |
| Hidaka, Y; Horie, M; Hotta, H; Iwasawa, Y; Kamei, T; Nagata, Y | 1 |
| Sathre, KA; Steer, CJ; Tsang, ML; Weatherbee, JA | 1 |
| Fiers, W; Libert, C; Van Bladel, S | 1 |
| Bosma, PJ; Kooistra, T | 1 |
| Grove, RI; Kiener, PA; Mazzucco, CE; Radka, SF; Shoyab, M | 1 |
| Baulieu, EE; Mercier-Bodard, C; Nivet, V | 1 |
| Hautanen, A; Keski-Oja, J; Koli, K; Lohi, J | 1 |
| Schneider, DJ; Sobel, BE | 1 |
| Hiramoto, M; Imaizumi, T; Kawamura, Y; Satoh, K; Takamatsu, M; Takamatsu, S; Yoshida, H | 1 |
| Charles, L; Feldman, DA; Rounsifer, ME; Weinhold, PA | 1 |
| Edwards, PA; Kutsunai, SY; Wilkin, DJ | 1 |
| Knowles, AF; Murray, SL | 1 |
| Dutton, AH; Singer, SJ; Valtersson, C | 1 |
| Fujita, T; Koizumi, T; Matsui, T; Nakagawa, T; Nakao, Y; Watanabe, S | 1 |
| Crabb, DW; Qulali, M; Ross, RA; Wolfla, CE | 1 |
| Chou, CK; Ting, LP; Tu, CL | 1 |
| Gedamu, L; Sadhu, C | 1 |
| Fujita, T; Koizumi, T; Maeda, S; Matsuda, S; Matsui, T; Nakagawa, T; Nakao, Y | 1 |
| Owensby, DA; Schwartz, AL; Sobel, BE | 1 |
| Bunn, HF; Dunning, SP; Goldberg, MA | 1 |
| McMorris, FA; Meyer, R | 1 |
| Begley, JA; Green-Colligan, PD; Hall, CA | 1 |
| Corsini, A; Fumagalli, R; Granata, A; Paoletti, R | 1 |
| Huber, BE; Thorgeirsson, SS | 1 |
| Pfeffer, SR | 1 |
| Ballesteros, AL; Finlay, TH; Karpatkin, M; Karpatkin, S | 1 |
| Cavia, E; Webb, TE | 1 |
| Higashi, T; Kashiwagi, K; Kudo, H | 1 |
| Martin, DW; Owen, NT | 1 |
| Miyaki, M; Moroashi, S; Ono, T | 1 |
| Cohen, H; Kulka, RG | 1 |
| Baxter, JD; Higgins, SJ; Rousseau, GG; Tomkins, GM | 1 |
| Barker, KL; Kenney, FT; Lee, KL | 2 |
| Emanuel, JR; Gelehrter, TD | 1 |
| Gelboin, HV; Miller, H; Whitlock, JP | 1 |
| Bancroft, FC; Goldlust, MB; Mayer, MM; Rommel, FA; Tashjian, AH | 1 |
| Plagemann, PG | 2 |
| Korbecki, M; Mahy, BW; Plagemann, PG; Ward, GA | 1 |
| Morris, HP; Webb, TE | 1 |
| Rizzo, AJ; Webb, TE | 1 |
| Morris, HP; Potter, VR; Watanabe, M | 1 |
| Ballard, PL; Tomkins, GM | 1 |
| Alonso, A; Citoler, P | 1 |
| Gauldie, J; Hiebert, M; Hillcoat, BL; Marshall, L | 1 |
| Higashi, T; Kashiwagi, K; Tobe, T | 1 |
| Chen, J; Coetzee, ML; Morris, HP; Ove, P | 1 |
| Gelehrter, TD; Risser, WL | 1 |
| Elford, HL | 1 |
| Erbe, J; Plagemann, PG | 2 |
| Borek, C; Burger, MM; Grob, M | 1 |
| Kaneko, I; Satoh, H; Ukita, T | 1 |
| Carnes, WH; Haggerty, DF; Popják, G; Young, PL | 1 |
| Dybing, E | 3 |
| Weber, G | 1 |
| Hogan, BL; Murden, S | 1 |
| Hoogenraad, NJ; Lee, DC | 1 |
| Harik, SI; Hollenberg, MD; Snyder, SH | 1 |
| Hogan, BL; McIlhinney, A | 1 |
| Balhorn, R; Chalkley, R; Granner, D; Tanphaichitr, N | 1 |
| Rothblat, GH | 1 |
| Kirsten, ES; Watson, JA | 1 |
| Katsuta, H; Nitta, K; Nose, K; Takaoka, T | 1 |
| Iwamoto, K; Martin, DW | 1 |
| Curran, JF; Thompson, EB; Tomkins, GM | 1 |
| Boctor, A; Grossman, A; Mendelson, D | 2 |
| Bresler, MA; Martin, DW; Tomkins, GM | 1 |
| Auricchio, F; Martin, D; Tompkins, G | 1 |
| Gelehrter, TD; Tomkins, GM | 1 |
| Becker, JE; Butcher, FR; Potter, VR | 1 |
| Levinson, BB; Stellwagen, RH; Tomkins, GM | 1 |
| Barnett, CA; Wicks, WD | 1 |
| Chaplain, M; Weiss, MC | 1 |
| Kenney, FT; Lee, KL | 1 |
| Boctor, A; Grossman, A; Masuda, Y | 1 |
| Hogan, BL | 1 |
| Stellwagen, RH | 1 |
| Benedict, WF; Nebert, DW; Thompson, EB | 1 |
3 review(s) available for cycloheximide and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Emerging roles of ferroptosis in liver pathophysiology.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexylamines; Deferoxamine; Disease Models, Animal; Disease Progression; Fatty Acids, Unsaturated; Ferroptosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Phenylenediamines; Quinoxalines; Reactive Oxygen Species; Reperfusion Injury; Spiro Compounds | 2020 |
Intracellular protein degradation.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Carcinoma, Hepatocellular; Cathepsins; Cycloheximide; Erythrocytes; Glucagon; Glucosephosphate Dehydrogenase; Glutathione; Hemoglobins; Humans; In Vitro Techniques; Insulin; Liver; Liver Neoplasms; Lysosomes; Membranes; Models, Biological; Peptide Hydrolases; Phosphoenolpyruvate Carboxykinase (GTP); Protein Conformation; Proteins; Reticulocytes; RNA, Transfer; Subcellular Fractions | 1977 |
Ordered and specific pattern of gene expression in neoplasia.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cycloheximide; DNA; Genes; Glucose-6-Phosphatase; Growth; Humans; Liver; Liver Neoplasms; Models, Biological; Molecular Conformation; Neoplasms; Oxidoreductases; Phosphotransferases | 1973 |
202 other study(ies) available for cycloheximide and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Colocalization of MID1IP1 and c-Myc is Critically Involved in Liver Cancer Growth via Regulation of Ribosomal Protein L5 and L11 and CNOT2.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cycloheximide; G1 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Humans; Immunohistochemistry; Liver Neoplasms; Poly(ADP-ribose) Polymerases; Protein Stability; Proteins; Proto-Oncogene Proteins c-myc; Repressor Proteins; Ribosomal Proteins; RNA Interference; Signal Transduction; Tissue Array Analysis; Up-Regulation | 2020 |
The ubiquitin ligase TRIM25 inhibits hepatocellular carcinoma progression by targeting metastasis associated 1 protein.
Topics: Atlases as Topic; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Movement; Cycloheximide; Disease Progression; Gene Expression Regulation, Neoplastic; Half-Life; Hepatocytes; Histone Deacetylases; Humans; Leupeptins; Liver Neoplasms; Protein Binding; Protein Stability; Proteolysis; Repressor Proteins; RNA, Small Interfering; Signal Transduction; Trans-Activators; Transcription Factors; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Ubiquitination | 2017 |
CD31 regulates metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma via the ITGB1-FAK-Akt signaling pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 1; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Platelet Endothelial Cell Adhesion Molecule-1; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2018 |
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation.
Topics: Animals; beta Catenin; Canagliflozin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Down-Regulation; Glucose; Glucose Transporter Type 1; Humans; Liver Neoplasms; Mice; Phosphorylation; Protein Phosphatase 2; RNA Interference; RNA, Small Interfering; Sodium-Glucose Transporter 2; Transplantation, Heterologous; Wnt Signaling Pathway | 2019 |
JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells.
Topics: Anthracenes; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Chelating Agents; Cycloheximide; Deferoxamine; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha; Vitamin E | 2013 |
Metabolism of radiolabeled methionine in hepatocellular carcinoma.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cycloheximide; Hepatocytes; Liver Neoplasms; Marmota; Methionine; Protein Biosynthesis; Radionuclide Imaging; Radiopharmaceuticals; Rats; Solubility; Tritium; Water | 2014 |
Possible roles of a tumor suppressor gene PIG11 in hepatocarcinogenesis and As2O3-induced apoptosis in liver cancer cells.
Topics: Adult; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Line, Tumor; Child; Cycloheximide; Dactinomycin; Down-Regulation; Female; Gene Expression; Gene Knockdown Techniques; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Male; Middle Aged; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Oxides; Protein Synthesis Inhibitors | 2009 |
Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines.
Topics: Base Sequence; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cell Movement; Cycloheximide; DNA Primers; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methionine Adenosyltransferase; Neoplasm Invasiveness; Protein Synthesis Inhibitors; Receptors, Thyroid Hormone; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Triiodothyronine | 2010 |
Reactive oxygen species is essential for cycloheximide to sensitize lexatumumab-induced apoptosis in hepatocellular carcinoma cells.
Topics: Antibodies, Monoclonal; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cycloheximide; Drug Interactions; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Intracellular Space; Liver Neoplasms; Reactive Oxygen Species | 2011 |
Sphingosine mediates TNFα-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Ceramidases; Ceramides; Cycloheximide; Gene Silencing; Intracellular Membranes; Lysosomes; Permeability; Rats; Receptors, Tumor Necrosis Factor; RNA, Small Interfering; Sphingomyelin Phosphodiesterase; Sphingosine; Tumor Necrosis Factor-alpha | 2012 |
Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells.
Topics: Adaptor Proteins, Signal Transducing; Adenoviridae; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; Caspase 3; Caspase 9; Caspases; Cycloheximide; Drug Synergism; Fas-Associated Death Domain Protein; Gene Expression Regulation, Enzymologic; Genetic Vectors; Hepatocytes; Humans; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Mitogen-Activated Protein Kinases; NF-kappa B; Protein Synthesis Inhibitors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Persistent nuclear accumulation of protein kinase CK2 during the G1-phase of the cell cycle does not depend on the ERK1/2 pathway but requires active protein synthesis.
Topics: Active Transport, Cell Nucleus; Carcinoma, Hepatocellular; Casein Kinase II; Cell Cycle; Cell Nucleus; Cycloheximide; G1 Phase; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 2002 |
Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Hepatocellular; Carrier Proteins; Chromans; Cycloheximide; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone; Tumor Cells, Cultured | 2003 |
Involvement of beta 1,4 galactosyltransferase 1 and Gal beta1-->4GlcNAc groups in human hepatocarcinoma cell apoptosis.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cycloheximide; Flow Cytometry; Galactosyltransferases; Humans; In Situ Nick-End Labeling; Lectins; Liver Neoplasms; N-Acetyllactosamine Synthase; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Transfection | 2003 |
Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma.
Topics: Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Survival; Cycloheximide; Dactinomycin; Down-Regulation; fas Receptor; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Liver; Liver Neoplasms; NF-kappa B; Oligodeoxyribonucleotides, Antisense; Protein Synthesis Inhibitors; Tumor Cells, Cultured | 2003 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cycloheximide; Cytosol; Endosomes; Enzyme Inhibitors; Hepatocytes; Hydrogen-Ion Concentration; Liver Neoplasms; Metabolism; Molecular Sequence Data; Nocodazole; Protein Synthesis Inhibitors; Rats; Recombinant Proteins; Time Factors; Wortmannin | 2003 |
Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromones; Cycloheximide; Depression, Chemical; Enzyme Inhibitors; Flavonoids; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Liver; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; RNA, Messenger; Sequence Alignment; Signal Transduction | 2003 |
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Blotting, Western; Carcinoma, Hepatocellular; CDC2 Protein Kinase; Cell Cycle; Cell Line; Cyclin B; Cycloheximide; Databases as Topic; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; F-Box Proteins; Genetic Vectors; Humans; Microscopy, Fluorescence; Mitosis; Models, Biological; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neoplasm Proteins; Nocodazole; Phosphoproteins; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Recombinant Proteins; Recombination, Genetic; RNA, Small Interfering; Sequence Homology, Amino Acid; Stem Cell Factor; Substrate Specificity; Temperature; Time Factors; Transfection; Ubiquitin | 2004 |
Tissue-specificity of apoptosis in hepatoma-derived cell lines.
Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Cycloheximide; Electrophoretic Mobility Shift Assay; Interleukin-1; Lipopolysaccharides; Liver Neoplasms; Protein Synthesis Inhibitors; Rats; Sorbitol; Transgenes; Tumor Necrosis Factor-alpha; Vinblastine; Vincristine | 2004 |
Genes transcriptionally modulated by interferon alpha2a correlate with the cytokine activity.
Topics: Apoptosis Regulatory Proteins; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Cytokines; Gene Expression Regulation, Neoplastic; Humans; Interferon alpha-2; Interferon-alpha; Interferon-Stimulated Gene Factor 3, gamma Subunit; K562 Cells; Liver Neoplasms; Membrane Transport Proteins; Molecular Sequence Data; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Proteolipids; Recombinant Proteins; Rhabdomyosarcoma; Ribonucleoproteins; STAT1 Transcription Factor; STAT2 Transcription Factor; Transcription, Genetic | 2004 |
Regulation of fibronectin by thyroid hormone receptors.
Topics: Carcinoma, Hepatocellular; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Fibronectins; Gene Expression Regulation; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinases; Smad3 Protein; Smad4 Protein; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Trans-Activators; Transforming Growth Factor beta; Triiodothyronine; Tumor Cells, Cultured | 2004 |
Functional expression and adaptive regulation of Na+ -dependent neutral amino acid transporter SNAT2/ATA2 in normal human astrocytes under amino acid starved condition.
Topics: Amino Acid Transport System A; Amino Acids; Astrocytes; beta-Alanine; Blotting, Northern; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Drug Interactions; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Time Factors | 2005 |
Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Cytochrome P-450 CYP1A1; Dactinomycin; Drug Interactions; Enzyme Induction; Gene Expression Regulation, Neoplastic; Hepatocytes; Leupeptins; Metals, Heavy; Mice; Polychlorinated Dibenzodioxins; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA, Messenger | 2005 |
Probucol enhances the expression of human hepatic scavenger receptor class B type I, possibly through a species-specific mechanism.
Topics: Adult; Animals; Anticholesteremic Agents; Atherosclerosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Disease Models, Animal; Gene Expression; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Probucol; Protein Synthesis Inhibitors; Rabbits; RNA, Messenger; Scavenger Receptors, Class B; Species Specificity | 2005 |
Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.
Topics: Arylsulfotransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxybenzoates; NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent.
Topics: Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carcinoma, Hepatocellular; Caspase 8; Caspases; Cathepsin B; Cathepsin D; Cell Line, Tumor; Cycloheximide; Digitonin; Dose-Response Relationship, Drug; Endosomes; L-Lactate Dehydrogenase; Leucine; Lysosomes; Mice; Microscopy, Fluorescence; Models, Biological; Models, Statistical; Oligonucleotides; Peptide Hydrolases; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; Sphingomyelins; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Heat shock protein 70 binds its own messenger ribonucleic acid as part of a gene expression self-limiting mechanism.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Dactinomycin; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Heat-Shock Response; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Precipitin Tests; Protein Synthesis Inhibitors; Puromycin; RNA, Messenger; Transcription, Genetic | 2006 |
Herpes simplex virus blocks Fas-mediated apoptosis independent of viral activation of NF-kappaB in human epithelial HEp-2 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cycloheximide; Epithelial Cells; fas Receptor; Fluorescent Antibody Technique, Indirect; Humans; Liver Neoplasms; Microscopy, Fluorescence; NF-kappa B; Protein Synthesis Inhibitors; Simplexvirus; Tumor Necrosis Factor-alpha; Virus Activation | 2007 |
Two specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate beta1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis.
Topics: Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromones; Cycloheximide; Drug Evaluation, Preclinical; Drug Synergism; Galactosyltransferases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Morpholines; Phosphatidylinositol 3-Kinases; Substrate Specificity; Up-Regulation; Wortmannin | 2007 |
Apoptosis of dedifferentiated hepatoma cells is independent of NF-kappaB activation in response to LPS.
Topics: Animals; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cycloheximide; Enzyme Inhibitors; I-kappa B Proteins; Lipopolysaccharides; Liver Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Synthesis Inhibitors; Rats | 2007 |
A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Carcinoma, Hepatocellular; Catalytic Domain; Cell Line; Cell Line, Tumor; Cells, Cultured; Cycloheximide; Embryo, Mammalian; Eukaryotic Initiation Factor-2B; Fibroblasts; Genes, Reporter; Histidine; Humans; Jurkat Cells; Kidney; Liver Neoplasms; Luciferases, Renilla; Mice; Models, Biological; Peptide Mapping; Phosphorylation; Protein Biosynthesis; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Serine; Time Factors; Transfection | 2008 |
Dehydroepiandrosterone effects on the mRNA levels of peroxisome proliferator-activated receptors and their coactivators in human hepatoma HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dehydroepiandrosterone; Gene Expression Regulation, Neoplastic; Humans; Peroxisome Proliferator-Activated Receptors; Protein Isoforms; RNA, Messenger | 2007 |
Regulation of tyrosine aminotransferase mRNA in HTC cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Emetine; Enzyme Induction; Kinetics; Liver Neoplasms; Protein Biosynthesis; Rats; RNA, Messenger; Tyrosine Transaminase | 1980 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Liver Neoplasms; Ornithine Decarboxylase; Peptides; Receptors, Cell Surface | 1981 |
Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.
Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Azides; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; Cycloheximide; Endocytosis; Humans; Kinetics; Liver Neoplasms; Orosomucoid; Protein Biosynthesis; Receptors, Cell Surface | 1982 |
Nuclear antigen detected in hepatoma cell lines containing integrated hepatitis B virus DNA.
Topics: Animals; Antigens, Nuclear; Carcinoma, Hepatocellular; Cell Line; Cell Nucleolus; Cell Nucleus; Cycloheximide; Genes, Viral; Hepatitis B Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Mice; Mice, Nude; Nucleoproteins; Recombination, Genetic | 1983 |
Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line.
Topics: Acute-Phase Proteins; alpha 1-Antitrypsin; Animals; Base Sequence; Blotting, Northern; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line; Cycloheximide; Dexamethasone; DNA Primers; DNA, Complementary; Endothelial Growth Factors; Erythropoietin; Fructose-Bisphosphate Aldolase; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Library; Glycolysis; Humans; Interleukin-6; Liver Neoplasms; Lymphokines; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Transcription, Genetic; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Resistance to Fas-mediated apoptosis in human hepatoma cells.
Topics: Adult; Amino Acid Sequence; Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cycloheximide; DNA, Complementary; fas Receptor; Humans; Liver Neoplasms; Male; Molecular Sequence Data; Repressor Proteins; Tumor Cells, Cultured | 1995 |
Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA, Neoplasm; Humans; Prostaglandin D2; Prostaglandins, Synthetic; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1995 |
Regulation of sex hormone-binding globulin secretion and gene expression by cycloheximide in vitro.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cycloheximide; Drug Interactions; Estradiol; Gene Expression Regulation; Humans; Insulin; RNA, Messenger; Sex Hormone-Binding Globulin; Triiodothyronine; Tumor Cells, Cultured | 1995 |
Inhibition of cytokine activation processes in vitro by tenidap, a novel anti-inflammatory agent.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indoles; Interleukin-1; Interleukin-6; Lipopolysaccharides; Liver Neoplasms; Monocytes; Oxindoles; Protein Biosynthesis; Tumor Cells, Cultured | 1995 |
Liver disease and serum hexosaminidase levels. Studies in a human hepatoma cell-line (Hep G2 cells).
Topics: Ammonium Chloride; beta-N-Acetylhexosaminidases; Carcinoma, Hepatocellular; Cycloheximide; Hexosaminidase A; Hexosaminidase B; Humans; Isoenzymes; Liver Neoplasms; Time Factors; Tumor Cells, Cultured | 1995 |
Transforming growth factor beta 1 selectively increases gene expression of the serine/threonine kinase receptor 1 (SKR1) in human hepatoma cell lines.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Receptors, Growth Factor; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured | 1994 |
Constitutive expression of functional P-glycoprotein in rat hepatoma cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Carrier Proteins; Clone Cells; Cycloheximide; Diethylnitrosamine; Doxorubicin; Drug Resistance; Female; Gene Expression; Glutathione Transferase; Liver Neoplasms; Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Neoplasm; Serum Albumin; Transcription, Genetic; Tumor Cells, Cultured; Verapamil | 1994 |
The modulation of apolipoprotein E gene expression by 3,3'-5-triiodothyronine in HepG2 cells occurs at transcriptional and post-transcriptional levels.
Topics: Apolipoproteins E; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cycloheximide; Gene Expression Regulation; Humans; Kinetics; Liver Neoplasms; Methionine; Orosomucoid; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Triiodothyronine; Tumor Cells, Cultured | 1994 |
Increase in neutral cholesteryl ester hydrolase activity produced by extralysosomal hydrolysis of high-density lipoprotein cholesteryl esters in rat hepatoma cells (H-35).
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol; Cholesterol Esters; Cycloheximide; Cytoplasm; Lipoproteins, HDL; Rats; Sterol Esterase | 1994 |
De novo sulfation of L-tyrosine in HepG2 human hepatoma cells and its possible functional implication.
Topics: Carcinoma, Hepatocellular; Cell Fractionation; Cycloheximide; Cytosol; Humans; Hydrogen-Ion Concentration; Kinetics; Liver Neoplasms; Metals; Sulfates; Sulfotransferases; Sulfur Radioisotopes; Tritium; Tumor Cells, Cultured; Tyrosine | 1994 |
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line; Cloning, Molecular; Cobalt; Cyanides; Cycloheximide; Enhancer Elements, Genetic; Erythropoietin; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Isoenzymes; L Cells; L-Lactate Dehydrogenase; Liver Neoplasms; Mice; Molecular Sequence Data; Oxygen; Phosphoglycerate Kinase; Promoter Regions, Genetic; Sequence Deletion; Sequence Homology, Nucleic Acid; TATA Box; Transfection; Tumor Cells, Cultured | 1994 |
Expression induced by interleukin-6 of tissue-type transglutaminase in human hepatoblastoma HepG2 cells.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Interleukin-6; Kinetics; Liver; Male; Mice; Transglutaminases; Tumor Cells, Cultured | 1993 |
Stimulation of sex hormone-binding globulin mRNA and attenuation of corticosteroid-binding globulin mRNA by triiodothyronine in human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Culture Media, Conditioned; Culture Media, Serum-Free; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Liver Neoplasms; RNA, Messenger; RNA, Ribosomal; Sex Hormone-Binding Globulin; Transcortin; Triiodothyronine; Tumor Cells, Cultured | 1994 |
Regulation of metallothionein mRNA in human hepatoma (HEP3B) cells.
Topics: Carcinoma, Hepatocellular; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Metallothionein; Puromycin; RNA, Messenger; Tumor Cells, Cultured | 1994 |
Induction of AP-1 (Fos/Jun) by chemical agents mediates activation of glutathione S-transferase and quinone reductase gene expression.
Topics: Arsenates; Arsenites; Base Sequence; Binding Sites; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Chlorides; Cycloheximide; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, Regulator; Glutathione Transferase; Humans; Hydrocarbons; Hydrogen Peroxide; Molecular Sequence Data; Phenobarbital; Phorbol Esters; Proto-Oncogene Proteins c-jun; Quinone Reductases; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Zinc Compounds | 1994 |
Modulation of the asialoglycoprotein receptor in human hepatoma cells: effect of glucose.
Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Binding Sites; Carcinoma, Hepatocellular; Culture Media; Cyclic GMP; Cycloheximide; Deoxyglucose; Glucose; Humans; Ligands; Liver Neoplasms; Precipitin Tests; Pyruvates; Pyruvic Acid; Receptors, Cell Surface; Tumor Cells, Cultured; Up-Regulation | 1994 |
Tumor necrosis factor up-regulates expression of low-density lipoprotein receptors on HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Humans; Lipoproteins, LDL; Liver Neoplasms; Receptors, LDL; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 1993 |
Trans-repressor BEF-1 phosphorylation. A potential control mechanism for human ApoE gene regulation.
Topics: Apolipoproteins E; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Kinetics; Liver Neoplasms; Nuclear Proteins; Phosphorylation; Protein Kinase C; Regulatory Sequences, Nucleic Acid; Repressor Proteins; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Chemotherapeutic agent CPT-11 induces the new expression of the apoptosis initiator to the cytoplasm.
Topics: Amino Acid Sequence; Animals; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Cell Extracts; Cell Nucleus; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Dactinomycin; DNA; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Molecular Sequence Data; Oligopeptides; Protein Synthesis Inhibitors; Rats; Tumor Cells, Cultured | 1996 |
Ginsenoside-Rg1 positively regulates cyclin E-dependent kinase activity in human hepatoma SK-HEP-1 cells.
Topics: Blotting, Western; Carcinoma, Hepatocellular; CDC2-CDC28 Kinases; Cell Division; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; Cycloheximide; DNA Replication; Drugs, Chinese Herbal; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ginsenosides; Histones; Humans; Precipitin Tests; Protein Serine-Threonine Kinases; Saponins; Tumor Cells, Cultured; Up-Regulation | 1996 |
Current issues in the regulation of signal transduction.
Topics: Animals; Carcinoma, Hepatocellular; Cell Count; Cycloheximide; Diet; Diglycerides; Humans; Inositol 1,4,5-Trisphosphate; Ischemia; Mice; Neoplasms; Phosphatidylinositols; Phosphotransferases (Alcohol Group Acceptor); Rats; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases | 1996 |
Intracellular glutathione level modulates the induction of apoptosis by delta 12-prostaglandin J2.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenites; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Division; Cycloheximide; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Glutathione; Humans; Liver Neoplasms; Prostaglandin D2; Sodium Compounds; Structure-Activity Relationship; Sulfhydryl Compounds; Tumor Cells, Cultured | 1996 |
Apoptosis induced by retinoic acid in Hep 3B cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cycloheximide; DNA, Neoplasm; Humans; Liver Neoplasms; Microscopy, Electron; Protein Synthesis Inhibitors; Tretinoin | 1996 |
Insulin-mimetic agents vanadate and pervanadate stimulate glucose but inhibit amino acid uptake.
Topics: Amino Acids; Animals; beta-Alanine; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Deoxyglucose; Drug Combinations; Enzyme Inhibitors; Glucose; Hypoglycemic Agents; Insulin; Muscle, Skeletal; Ouabain; Protein Tyrosine Phosphatases; Rats; Vanadates | 1997 |
Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression.
Topics: Adrenalectomy; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Gene Expression Regulation; Glucocorticoids; Insulin Antagonists; Liver; Male; Methionine Adenosyltransferase; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic; Triamcinolone | 1997 |
Enhanced expression of glucose-6-phosphate dehydrogenase in human cells sustaining oxidative stress.
Topics: Carcinoma, Hepatocellular; Catalase; Cycloheximide; Dactinomycin; Diamide; Enzyme Induction; Glucosephosphate Dehydrogenase; Glutathione; Humans; Hydrogen Peroxide; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Oxidation-Reduction; Oxidative Stress; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1997 |
Inflammatory cytokines and type I 5'-deiodinase expression in phi1 rat liver cells.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Dose-Response Relationship, Drug; Interleukin-1; Interleukin-8; Iodide Peroxidase; Rats; RNA, Messenger; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Cycloheximide; Endothelial Growth Factors; Gene Expression Regulation; Glioblastoma; Guanylate Cyclase; Humans; Liver Neoplasms; Lymphokines; Nitric Oxide; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Regulation of heparin-binding EGF-like growth factor expression by phorbol ester in a human hepatoma-derived cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Naphthalenes; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Increased transcript level of RBM3, a member of the glycine-rich RNA-binding protein family, in human cells in response to cold stress.
Topics: Carcinoma, Hepatocellular; Cold Temperature; Cycloheximide; HeLa Cells; Humans; Kidney Neoplasms; Kinetics; Leukemia; Liver Neoplasms; Protein Synthesis Inhibitors; Puromycin; RNA-Binding Proteins; RNA, Messenger; Tissue Distribution; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1997 |
Selective fast degradation of cytochrome P-450 2E1 in serum-deprived hepatoma cells by a mechanism sensitive to inhibitors of vesicular transport.
Topics: Animals; Biological Transport; Blood Physiological Phenomena; Carcinoma, Hepatocellular; Cycloheximide; Cytochrome P-450 CYP2E1; Endoplasmic Reticulum; Rats; Tumor Cells, Cultured | 1997 |
Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation.
Topics: Carcinoma, Hepatocellular; Cell Survival; Cycloheximide; DNA Fragmentation; Genes, jun; Genes, Reporter; Glutathione; Humans; Hydrogen Peroxide; Liver; Liver Neoplasms; Luciferases; Necrosis; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Effect of heat shock treatment on the production of variant testosterone-repressed prostate message-2 (TRPM-2) mRNA in culture cells.
Topics: Alternative Splicing; Animals; Carcinoma, Hepatocellular; Clusterin; Complement Inactivator Proteins; Cycloheximide; Fibroblasts; Gene Expression Regulation, Neoplastic; Glycoproteins; Heat-Shock Response; Humans; Liver; Mice; Molecular Chaperones; Neoplasm Proteins; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Cells, Cultured | 1997 |
Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Carcinoma, Hepatocellular; Choriocarcinoma; Colforsin; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Fadrozole; Humans; Liver Neoplasms; Neoplasm Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Triazoles; Tumor Cells, Cultured | 1998 |
A serum shock induces circadian gene expression in mammalian tissue culture cells.
Topics: Animals; Biological Clocks; Blood; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line; Circadian Rhythm; Cycloheximide; Fibroblasts; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Liver; Nuclear Proteins; Period Circadian Proteins; Protein Synthesis Inhibitors; Rats; RNA, Messenger; RNA, Neoplasm; Transcription Factors; Tumor Cells, Cultured | 1998 |
Induction of mouse retinol binding protein gene expression by cyclic AMP in Hepa 1-6 cells.
Topics: Animals; Carcinoma, Hepatocellular; Colforsin; Cyclic AMP; Cycloheximide; Gene Expression Regulation; Mice; Molecular Sequence Data; Retinol-Binding Proteins; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Transcriptional and post-transcriptional regulation of complement factor I (CFI) gene expression in Hep G2 cells by interleukin-6.
Topics: Base Sequence; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Complement Factor I; Consensus Sequence; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Genes, Reporter; Half-Life; Humans; Interleukin-1; Interleukin-6; Kinetics; Liver Neoplasms; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Transfection | 1998 |
Regulation of erythropoietin gene expression depends on two different oxygen-sensing mechanisms.
Topics: Carcinoma, Hepatocellular; Cell Hypoxia; Cycloheximide; Deferoxamine; Erythropoietin; Gene Expression Regulation; Humans; Oxygen; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
The AU-rich 3' untranslated region of human MDR1 mRNA is an inefficient mRNA destabilizer.
Topics: 3' Untranslated Regions; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Carcinoma, Hepatocellular; Cycloheximide; Genes, fos; Genes, myc; Globins; Glyceraldehyde-3-Phosphate Dehydrogenases; Half-Life; Humans; Liver Neoplasms; Lymphokines; Protein Synthesis Inhibitors; RNA-Binding Proteins; Tumor Cells, Cultured | 1999 |
Critical role of p42/44(MAPK) activation in anisomycin and hepatocyte growth factor-induced LDL receptor expression: activation of Raf-1/Mek-1/p42/44(MAPK) cascade alone is sufficient to induce LDL receptor expression.
Topics: Anisomycin; Carcinoma, Hepatocellular; Cycloheximide; Enzyme Activation; Gene Expression Regulation; Hepatocyte Growth Factor; Humans; Liver Neoplasms; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Puromycin; Receptors, LDL; Tumor Cells, Cultured | 1999 |
Regulation of mitochondrial cytochrome b mRNA by copper in cultured human hepatoma cells and rat liver.
Topics: Animals; Carcinoma, Hepatocellular; Chelating Agents; Copper; Cycloheximide; Cytochrome b Group; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrogen Peroxide; Liver; Male; Mitochondria, Liver; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Analysis, DNA; Thapsigargin; Tumor Cells, Cultured; Zinc | 1999 |
Hepatitis C virus core protein does not inhibit apoptosis in human hepatoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; CHO Cells; Cricetinae; Cycloheximide; fas Receptor; Fluorescent Antibody Technique, Indirect; Genes, myc; Hepacivirus; Humans; Liver Neoplasms; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Viral Core Proteins | 1999 |
Transcriptional modulation of the human complement factor I gene in Hep G2 cells by protein kinase C activation.
Topics: Carcinoma, Hepatocellular; Complement Factor I; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Mutagenesis, Site-Directed; Naphthalenes; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyrrolidines; Recombinant Proteins; RNA Stability; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiocarbamates; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1999 |
Transcriptional regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells: a negative role for NF-kappaB.
Topics: Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cycloheximide; DNA Primers; DNA, Neoplasm; Fibronectins; Gene Expression Regulation; Genes, Reporter; Humans; Molecular Sequence Data; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Sequence Deletion; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Phosphatidylinositol 3-kinase contributes to Erk1/Erk2 MAP kinase activation associated with hepatocyte growth factor-induced cell scattering.
Topics: Carcinoma, Hepatocellular; Cell Movement; Chromones; Cycloheximide; Enzyme Inhibitors; Flavonoids; Hepatocyte Growth Factor; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitin-Protein Ligases | 1999 |
Visualization of gap junction mobility in living cells.
Topics: Animals; Carcinoma, Hepatocellular; Connexins; Cycloheximide; DNA, Complementary; Endocytosis; Epidermal Growth Factor; Epithelial Cells; Gap Junction beta-1 Protein; Gap Junctions; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Microscopy, Fluorescence; Microscopy, Video; Protein Synthesis Inhibitors; Rats; Recombinant Fusion Proteins; Tumor Cells, Cultured | 2000 |
Induction of apoptosis in normal cultured rat hepatocytes and in Hep3B, a human hepatoma cell line.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Carcinoma, Hepatocellular; Cell Culture Techniques; Cycloheximide; Fluorescent Dyes; Hepatocytes; Humans; Indoles; Liver Neoplasms; Okadaic Acid; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tretinoin; Tumor Cells, Cultured | 2000 |
An insight into the mechanism of cytotoxicity of ricin to hepatoma cell: roles of Bcl-2 family proteins, caspases, Ca(2+)-dependent proteases and protein kinase C.
Topics: Apoptosis; Calpain; Carcinoma, Hepatocellular; Caspases; Cells, Cultured; Cycloheximide; Drug Synergism; Humans; Liver Neoplasms; Protein Kinase C; Proteins; Proto-Oncogene Proteins c-bcl-2; Ricin | 2001 |
Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Humans; Liver; Liver Neoplasms; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Polychlorinated Dibenzodioxins; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Focal adhesion kinase affects the sensitivity of human hepatocellular carcinoma cell line SMMC-7721 to tumor necrosis factor-alpha/cycloheximide-induced apoptosis by regulating protein kinase B levels.
Topics: Androstadienes; Apoptosis; Carcinoma, Hepatocellular; Cycloheximide; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Liver Neoplasms; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Wortmannin | 2001 |
Mechanisms of the induction of apoptosis in human hepatoma cells by tumour necrosis factor-alpha.
Topics: Acridine Orange; Apoptosis; Calcium; Carcinoma, Hepatocellular; Cycloheximide; Flow Cytometry; Humans; Hypoxanthine; Lipid Peroxidation; Liver Neoplasms; Oxidative Stress; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2001 |
Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line; Cisplatin; Cycloheximide; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; NF-kappa B; Peptides; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2002 |
Differential degradation of messenger RNAs in mammalian cells.
Topics: Alanine Transaminase; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Fluorides; Hydrocortisone; Liver Neoplasms; Peptide Chain Elongation, Translational; Polyribosomes; Puromycin; RNA, Messenger; Tyrosine Transaminase | 1976 |
Involvement of protein synthesis in the post-translational control of glutamine synthetase activity of cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Emetine; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Protein Biosynthesis | 1976 |
Relationship between phosphorylation of tyrosine aminotransferase and regulation of its synthesis by cyclic AMP and hormones.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dexamethasone; Insulin; Liver Neoplasms; Phosphates; Protein Kinases; Rats; Tyrosine Transaminase | 1978 |
Spermine inhibits induction of ornithine decarboxylase by cyclic AMP but not by dexamethasone in rat hepatoma cells.
Topics: Animals; Bucladesine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Liver Neoplasms; Ornithine Decarboxylase; Rats; Spermine | 1975 |
Lysis of tumor cells by antibody and complement. III. Lack of correlation between antigen movement and cell lysis.
Topics: Animals; Antibodies; Antibodies, Neoplasm; Antigens; Azides; Carcinoma, Hepatocellular; Cell Membrane; Colchicine; Complement System Proteins; Cyanides; Cycloheximide; Cytochalasin B; Cytotoxicity Tests, Immunologic; Dactinomycin; Fluorescent Antibody Technique; Fluorides; Forssman Antigen; Guinea Pigs; Immunity, Cellular; Iodoacetates; Liver Neoplasms; Puromycin; Staining and Labeling | 1975 |
Influence of serum and insulin on the accumulation of aminoisobutyrate by rat hepatoma cells.
Topics: Alanine; Aminoisobutyric Acids; Animals; Blood; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Insulin; Kinetics; Liver Neoplasms; Rats | 1976 |
Complement biosynthesis in vitro by rat hepatoma cell strains.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Complement Inactivator Proteins; Complement System Proteins; Cycloheximide; Erythrocytes; Humans; Hydrocortisone; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Isoleucine; Leucine; Liver Neoplasms; Lysine; Male; Rabbits; Rats; Sheep; Valine | 1975 |
Studies on highly metabolically active acetylation and phosphorylation of histones.
Topics: Acetates; Acetylation; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Cycloheximide; Histones; Liver Neoplasms; Neoplasms, Experimental; Phosphates; Phosphorus Radioisotopes; Tritium | 1975 |
Requirement for protein synthesis in the regulation of protein breakdown in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Insulin; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Pactamycin; Protein Biosynthesis; Puromycin; RNA, Transfer | 1975 |
Cell density dependent regulation of phenylalanine hydroxylase activity in hepatoma cells. Evidence for both an active and inactive enzyme form.
Topics: Animals; Bucladesine; Carcinoma, Hepatocellular; Cell Count; Cell Division; Cell Line; Cycloheximide; Hydrocortisone; Immunoassay; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine Hydroxylase; Rats | 1976 |
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures.
Topics: Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Kinetics; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; Putrescine | 1976 |
Mechanism of inactivation of phenylalanine hydroxylase by p-chlorophenylalanine in hepatome cells in culture. Two possible models.
Topics: Animals; Antigens; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Fenclonine; Isoenzymes; Kinetics; Liver; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine Hydroxylase; Rats | 1976 |
Stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.
Topics: Animals; Bucladesine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Drug Stability; Enzyme Induction; Hot Temperature; Kinetics; Liver; Liver Neoplasms; Liver Regeneration; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Precipitin Tests; Rats; Spermidine; Spermine; Time Factors | 1976 |
Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells.
Topics: Amino Acids; Arginine; Canavanine; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Fetal Blood; Insulin; Leucine; Leupeptins; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Pepstatins; Phenylmethylsulfonyl Fluoride; Phosphoenolpyruvate Carboxykinase (GTP); Puromycin | 1976 |
Effects of alpha-amanitin, cycloheximide, and thioacetamide on low molecular weight nuclear RNA.
Topics: Acetamides; Amanitins; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Cycloheximide; Dose-Response Relationship, Drug; Liver; Liver Neoplasms; Male; Molecular Weight; Neoplasms, Experimental; Phosphates; Rats; RNA; RNA, Neoplasm; Thioacetamide | 1976 |
Thymidylate synthetase activity in the Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Folic Acid; Liver Neoplasms; Male; Methotrexate; Methyltransferases; Neoplasms, Experimental; Puromycin; Rats; Tetrahydrofolates; Thymidylate Synthase | 1976 |
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells.
Topics: Cadaverine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Kinetics; Liver Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Effect of alpha-methyl ornithine on ornithine decarboxylase activity of rat hepatoma cells in culture.
Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; Liver Neoplasms; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; RNA, Messenger | 1977 |
[Characteristics of mRNA metabolism in tumor cells. The hypothesis of the uncoupling of the processes of polyribosome formation and functioning in the tumor cell].
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Cell Nucleus; Cycloheximide; Cytoplasm; Dactinomycin; Free Radicals; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine; Polyribosomes; Rats; RNA, Messenger; RNA, Neoplasm; Uridine | 1977 |
The specific release of sialytransferase activity by human hepatoma cell lines.
Topics: Carcinoma, Hepatocellular; Cell Line; Child, Preschool; Chromatography, Gel; Cycloheximide; Deoxyglucose; Galactosyltransferases; Humans; Liver; Liver Neoplasms; Molecular Weight; Sialyltransferases; Subcellular Fractions; Transferases | 1979 |
Analysis of the induction and deinduction of tyrosine aminotransferase in enucleated HTC cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cycloheximide; Cytochalasin B; Dexamethasone; Enzyme Induction; Liver Neoplasms; Neoplasm Proteins; Rats; Tyrosine Transaminase | 1975 |
Increased particulate and decreased soluble guanylate cyclase activity in regenerating liver, fetal liver, and hepatoma.
Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cell Membrane; Cycloheximide; Cytosol; Fetus; Guanylate Cyclase; Liver; Liver Neoplasms; Liver Regeneration; Male; Microsomes, Liver; Neoplasms, Experimental; Rats; Time Factors | 1975 |
Epidermal growth factor enhances insulin-like growth factor binding protein-1 synthesis in human hepatoma cells.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Carrier Proteins; Cell Nucleus; Cycloheximide; DNA Probes; Epidermal Growth Factor; Humans; Insulin-Like Growth Factor Binding Protein 1; Kinetics; Liver Neoplasms; RNA, Messenger; Somatomedins; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Transcriptional regulation of transferrin and albumin genes by retinoic acid in human hepatoma cell line Hep3B.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Liver Neoplasms; RNA, Neoplasm; Serum Albumin; Transcription, Genetic; Transferrin; Tretinoin | 1992 |
The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells. ApoB 100 is cotranslationally integrated into lipoproteins.
Topics: Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Cycloheximide; Humans; Kinetics; Lipoproteins; Liver Neoplasms; Methionine; Protein Biosynthesis; Sulfur Radioisotopes; Transfection | 1992 |
Regulation of insulin receptor gene expression. Cell cycle-mediated effects on insulin receptor mRNA stability.
Topics: Actins; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cycloheximide; Dactinomycin; DNA Probes; Exons; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Kinetics; Liver Neoplasms; Receptor, Insulin; Restriction Mapping; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.
Topics: Alkaloids; Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Humans; Interleukin-6; Kinetics; Liver Neoplasms; Macromolecular Substances; Phorbol Esters; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-6; Recombinant Proteins; Staurosporine; Transfection; Tumor Cells, Cultured | 1992 |
Apolipoprotein synthesis and secretion in Hep G2 cells: effects of monensin and cycloheximide.
Topics: Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Carcinoma, Hepatocellular; Cycloheximide; Humans; Lipoproteins; Liver; Liver Neoplasms; Monensin; Triglycerides; Tumor Cells, Cultured | 1992 |
Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells.
Topics: Acute-Phase Proteins; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Humans; Interleukin-6; Liver Neoplasms; Nuclear Proteins; Oligonucleotides; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.
Topics: Acetates; Anticholesteremic Agents; Benzylamines; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cycloheximide; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Nucleic Acid Hybridization; Oxygenases; RNA, Neoplasm; Simvastatin; Squalene Monooxygenase; Thiophenes | 1991 |
Binding and internalization of transforming growth factor-beta 1 by human hepatoma cells: evidence for receptor recycling.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Chloroquine; Cycloheximide; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Monensin; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured | 1991 |
Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Humans; Interleukin-6; Kinetics; Liver; Liver Neoplasms; Rats; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 1991 |
Different induction of two plasminogen activator inhibitor 1 mRNA species by phorbol ester in human hepatoma cells.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cycloheximide; Enzyme Activation; Humans; Liver Neoplasms; Plasminogen Inactivators; Protein Biosynthesis; Protein Kinase C; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1991 |
Oncostatin M up-regulates low density lipoprotein receptors in HepG2 cells by a novel mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cross-Linking Reagents; Cycloheximide; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; Humans; Isoquinolines; Liver Neoplasms; Oncostatin M; Peptides; Phosphorylation; Piperazines; Receptors, Cell Surface; Receptors, Cytokine; Receptors, LDL; Receptors, Oncostatin M; Tumor Cells, Cultured; Tyrosine; Up-Regulation | 1991 |
Effects of hormones on SBP mRNA levels in human cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cycloheximide; Endometrial Neoplasms; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Insulin; Liver Neoplasms; Male; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Sex Hormone-Binding Globulin; Steroids; Triiodothyronine; Tumor Cells, Cultured | 1991 |
Enhancement of vitronectin expression in human HepG2 hepatoma cells by transforming growth factor-beta 1.
Topics: Blood Proteins; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Glycoproteins; Growth Substances; Humans; Kinetics; Liver Neoplasms; Plasminogen Inactivators; Poly A; Receptors, Immunologic; Receptors, Vitronectin; RNA, Messenger; Transforming Growth Factor beta; Vitronectin | 1991 |
Augmentation of synthesis of plasminogen activator inhibitor type 1 by insulin and insulin-like growth factor type I: implications for vascular disease in hyperinsulinemic states.
Topics: Blotting, Northern; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cycloheximide; Humans; Insulin; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Kinetics; Liver Neoplasms; Melanoma; Plasminogen Inactivators; RNA, Messenger | 1991 |
Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetophenones; Carcinoma, Hepatocellular; Cell Survival; Chromatography, Gel; Cycloheximide; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Humans; Hydrolysis; Isoflurophate; L-Lactate Dehydrogenase; Liver Neoplasms; Methionine; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Precipitin Tests; Tumor Cells, Cultured | 1991 |
Control of phosphatidylcholine synthesis in Hep G2 cells. Effect of fatty acids on the activity and immunoreactive content of choline phosphate cytidylyltransferase.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Choline-Phosphate Cytidylyltransferase; Cycloheximide; Digitonin; Liver Neoplasms; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phosphatidylcholines; Tumor Cells, Cultured | 1991 |
Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by ph
Topics: Amino Acid Sequence; Base Sequence; Carcinoma, Hepatocellular; Cycloheximide; Dimethylallyltranstransferase; DNA; DNA Probes; Gene Expression Regulation; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Liver Neoplasms; Molecular Sequence Data; Nucleic Acid Hybridization; Oxo-Acid-Lyases; Placenta; Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transferases; Tumor Cells, Cultured | 1990 |
Butyrate induces an ectoMg2(+)-ATPase activity in Li-7A human hepatoma cells.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Triphosphatases; Biological Transport, Active; Bucladesine; Butyrates; Carcinoma, Hepatocellular; Cell Division; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Epidermal Growth Factor; Fatty Acids; Humans; Kinetics; Liver Neoplasms; Neoplasm Proteins; Time Factors; Tumor Cells, Cultured | 1990 |
Transfer of secretory proteins from the endoplasmic reticulum to the Golgi apparatus: discrimination between homologous and heterologous transfer in intact heterokaryons.
Topics: Carcinoma, Hepatocellular; Cell Fusion; Cell Line; Cycloheximide; Endoplasmic Reticulum; Fluorescent Antibody Technique; Golgi Apparatus; Humans; Liver Neoplasms; Membrane Fusion; Proteins; Serum Albumin | 1990 |
Effects of alpha-difluoromethyl ornithine on alpha-fetoprotein and albumin secretion in human hepatoma cell line, PLC/PRF/5.
Topics: Albumins; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Eflornithine; Humans; Liver Neoplasms; Ornithine | 1985 |
Regulation of the expression of the rat alcohol dehydrogenase gene by glucocorticoids.
Topics: Alcohol Dehydrogenase; Animals; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Ethanol; Gene Expression Regulation; Genes; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Puromycin; Rats; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Insulin-induced expression of human heat-shock protein gene hsp70.
Topics: Carcinoma, Hepatocellular; Cycloheximide; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gene Expression Regulation; Heat-Shock Proteins; Hepatitis B Surface Antigens; Humans; Insulin; Kinetics; Liver Neoplasms; Platelet-Derived Growth Factor; Receptor, Insulin; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Metal-specific posttranscriptional control of human metallothionein genes.
Topics: Actins; Carcinoma, Hepatocellular; Cell Line; Copper; Cycloheximide; Dactinomycin; Gene Expression Regulation; Genes; Humans; Kinetics; Liver Neoplasms; Metallothionein; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Zinc | 1989 |
Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Heme Oxygenase (Decyclizing); Hot Temperature; Humans; Kinetics; Liver Neoplasms; Mixed Function Oxygenases; RNA, Messenger; Tumor Cells, Cultured | 1989 |
Effects of sodium n-butyrate on alpha-fetoprotein and albumin secretion in the human hepatoma cell line PLC/PRF/5.
Topics: Albumins; alpha-Fetoproteins; Butyrates; Butyric Acid; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Humans; Liver Neoplasms | 1985 |
Receptor-mediated endocytosis of tissue-type plasminogen activator by the human hepatoma cell line Hep G2.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Endocytosis; Humans; Kinetics; Liver Neoplasms; Tissue Plasminogen Activator | 1988 |
Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein.
Topics: Anaerobiosis; Carbon Monoxide; Carcinoma, Hepatocellular; Cell Line; Cobalt; Cycloheximide; Erythropoietin; Gene Expression Regulation; Genes; Hemeproteins; Humans; Iron; Liver Neoplasms; Manganese; Nickel; Transcription, Genetic | 1988 |
The synergistic interaction of hydrocortisone and dibutyryl cyclic AMP during enzyme induction in hybrids between rat C6 glioma cells and FU5AH hepatoma cells.
Topics: Amanitins; Animals; Bucladesine; Carcinoma, Hepatocellular; Cycloheximide; Drug Synergism; Enzyme Induction; Glioma; Glycerolphosphate Dehydrogenase; Hybrid Cells; Hydrocortisone; Kinetics; Liver Neoplasms; Rats; Tyrosine Transaminase | 1986 |
Synthesis of transcobalamin II by cultured human hepatocytes.
Topics: Apoproteins; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Humans; Immunologic Techniques; Leucine; Liver Neoplasms; Transcobalamins | 1985 |
Calcium antagonists and low density lipoproteins metabolism by human fibroblasts and by human hepatoma cell line HEP G2.
Topics: Amanitins; Biotransformation; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Diltiazem; Fibroblasts; Humans; Lipoproteins; Lipoproteins, LDL; Liver Neoplasms; Papaverine; Receptors, LDL; Verapamil | 1986 |
Analysis of c-myc expression in a human hepatoma cell line.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; DNA, Neoplasm; Gene Amplification; Gene Expression Regulation; Humans; Liver Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Neoplasm; Transcription, Genetic; Translocation, Genetic | 1987 |
The endosomal concentration of a mannose 6-phosphate receptor is unchanged in the absence of ligand synthesis.
Topics: Asialoglycoproteins; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Cycloheximide; Endocytosis; Golgi Apparatus; Humans; Hydrolases; Isotope Labeling; Lactoperoxidase; Liver Neoplasms; Lysosomes; Orosomucoid; Protein Biosynthesis; Protein Processing, Post-Translational; Receptor, IGF Type 2 | 1987 |
Effect of warfarin on prothrombin synthesis and secretion in human Hep G2 cells.
Topics: Acetylglucosaminidase; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Glycosylation; Humans; Liver Neoplasms; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Protein Biosynthesis; Prothrombin; Time Factors; Warfarin | 1987 |
Modified induction of ornithine decarboxylase by factors which affect liver regeneration.
Topics: Adrenal Glands; Adrenalectomy; Age Factors; Animals; Azacitidine; Azaguanine; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Hepatectomy; Hydrocortisone; Liver; Liver Neoplasms; Liver Regeneration; Male; Ornithine; Rats; Solubility | 1972 |
Specific precipitation of catalase-synthesizing ribosomes by anti-catalase antiserum.
Topics: Acetamides; Animals; Antibodies; Carcinoma, Hepatocellular; Catalase; Cycloheximide; Depression, Chemical; gamma-Globulins; Immune Sera; Liver; Liver Neoplasms; Neoplasms, Experimental; Precipitin Tests; Rats; Ribosomes; Spectrum Analysis; Ultraviolet Rays | 1972 |
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium | 1972 |
Single strand scission and repair of DNA in bleomycin-sensitive and resistant rat ascites hepatoma cells.
Topics: Animals; Bleomycin; Carcinoma, Hepatocellular; Cells, Cultured; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Liver Neoplasms; Neoplasms, Experimental; Rats; Sodium Dodecyl Sulfate; Thymidine; Tritium | 1973 |
Regulation of glutamine synthetase activity of hepatoma tissue culture cells by glutamine and dexamethasone.
Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Fluorides; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Liver Neoplasms; Time Factors; Tyrosine Transaminase | 1973 |
Steroid-induced nuclear binding of glucocorticoid receptors in intact hepatoma cells.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleus; Cells, Cultured; Chromatography, Thin Layer; Corticosterone; Cycloheximide; Cytosol; Dactinomycin; Dexamethasone; Enzyme Induction; Hydrocortisone; Kinetics; Liver; Liver Neoplasms; Progesterone; Rats; Receptors, Cell Surface; Temperature; Time Factors; Tritium; Tyrosine Transaminase | 1973 |
Hormonal mechanisms in regulation of gene expression.
Topics: Animals; Antigen-Antibody Reactions; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Enzyme Induction; Genes; Hydrocortisone; Immunodiffusion; Insulin; Isotope Labeling; Kinetics; Leucine; Liver; Liver Neoplasms; Rats; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1973 |
Hormonal regulation of protein degradation in hepatoma cells in tissue culture.
Topics: Animals; Blood; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; In Vitro Techniques; Insulin; Leucine; Liver Neoplasms; Proteins; Rats; Tritium; Tyrosine Transaminase | 1974 |
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Deoxyadenosines; Dexamethasone; Drug Synergism; Enzyme Induction; Leucine; Liver Neoplasms; Microsomes; Mixed Function Oxygenases; Neoplasm Proteins; Protein Biosynthesis; Rats; RNA, Neoplasm; Spectrophotometry; Transcription, Genetic; Tritium; Tyrosine Transaminase; Uridine | 1974 |
Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Clone Cells; Complement System Proteins; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Hemolysis; Hydrocortisone; Liver Neoplasms; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA; Temperature | 1970 |
On the mechanism of phenethyl alcohol-induced loss of polyribosomes and their re-formation after reversal in rat hepatoma cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Dactinomycin; Ethanol; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Spectrophotometry; Time Factors; Tritium; Uridine | 1968 |
Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. I. Incorporation of choline into phosphatidylcholine of mitochondria and other membranous structures and effect of metabolic inhibitors.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, Density Gradient; Chloramphenicol; Choline; Chromatography, Thin Layer; Culture Techniques; Cycloheximide; Dactinomycin; Dihydrolipoamide Dehydrogenase; Electron Transport Complex IV; Glucose-6-Phosphatase; Liver Neoplasms; Malate Dehydrogenase; Microscopy, Electron; Mitochondria; Phosphatidylcholines; Puromycin; Rats; Tritium; Uridine | 1968 |
Relationship between uridine kinase activity and rate of incorporation of uridine into acid-soluble pool and into RNA during growth cycle of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell-Free System; Chromatography, Paper; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Electrophoresis; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Phosphotransferases; Proteins; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1969 |
Properties of the inactive ribosomal components in rat liver and hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cycloheximide; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasm Transplantation; Neoplasms, Experimental; Protein Biosynthesis; Rats; Ribosomes | 1969 |
Ribosome formation in rat liver: evidence for post-transcriptional control.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Azaguanine; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Cycloheximide; Cytoplasm; Depression, Chemical; Feedback; Leucine; Liver; Liver Neoplasms; Male; Metabolism; Neoplasms, Experimental; Orotic Acid; Puromycin; Pyrrolidines; Rats; Ribosomes; RNA; Stimulation, Chemical; Time Factors; Tryptophan | 1969 |
Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.
Topics: Animals; Benzopyrenes; Carcinoma, Hepatocellular; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms, Experimental; Puromycin; Rats | 1970 |
Glucocorticoid-induced alteration of the surface membrane of cultured hepatoma cells.
Topics: Agglutination Tests; Amnion; Animals; Bone Marrow; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Dinitrophenols; Edetic Acid; Glass; Half-Life; HeLa Cells; Histocytochemistry; Humans; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Liver Neoplasms; Methods; Microscopy, Phase-Contrast; Proteins; RNA; Temperature; Time Factors | 1970 |
[Action of cycloheximide on protein metabolism of liver neoplasms induced by diethylnitrosamine].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Nucleus; Cycloheximide; Liver; Liver Neoplasms; Neoplasm Proteins; Nitrosamines; Phenylalanine; Radiochemistry; Rats; Tritium | 1971 |
Stabilization of dihydrofolate reductase by inhibitors in vivo and in vitro.
Topics: Animals; Biodegradation, Environmental; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Cycloheximide; Drug Stability; Electrophoresis; Enzyme Activation; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Liver Neoplasms; Methotrexate; Mice; Rats; Tetrahydrofolate Dehydrogenase; Triamterene; Trimethoprim | 1971 |
Studies on rat liver catalase. V. Incorporation of 14 C-leucine into catalase by isolated rat liver ribosomes.
Topics: Acetamides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Catalase; Cell-Free System; Cycloheximide; Dactinomycin; Depression, Chemical; In Vitro Techniques; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotides; Puromycin; Rats; Ribonucleases; Ribosomes; Triazoles | 1971 |
Differences in synthesis and degradation of serum proteins in normal and hepatoma-bearing animals.
Topics: Albumins; Animals; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Cell-Free System; Chromatography; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Liver; Liver Neoplasms; Male; Microsomes, Liver; Neoplasms, Experimental; Protein Biosynthesis; Puromycin; Rats; Serum Albumin; Serum Globulins; Tritium | 1972 |
Hormonal modulation of amino acid transport in rat hepatoma cells in tissue culture.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Culture Media; Cycloheximide; Dactinomycin; Depression, Chemical; Dexamethasone; Diffusion; Drug Synergism; Insulin; Kinetics; Liver Neoplasms; Neoplasm Proteins; Rats; Stimulation, Chemical; Swine; Time Factors | 1973 |
Functional regulation of mammalian ribonucleotide reductase.
Topics: Animals; Carcinoma, Hepatocellular; Cycloheximide; DNA; Liver; Liver Neoplasms; Neoplasms, Experimental; Oxidoreductases; Rats; Ribonucleotides | 1972 |
Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Chromatography, Paper; Cycloheximide; Cytochalasin B; Diffusion; Dipyridamole; Glucosamine; Glucose; Lactates; Liver Neoplasms; Neoplasms, Experimental; Puromycin; Rats; Ribonucleotides; Tritium; Uracil Nucleotides; Uridine; Uridine Diphosphate Sugars | 1973 |
Surface alterations in transformed epithelial and fibroblastic cells in culture: a disturbance of membrane degradation versus biosynthesis?
Topics: Animals; Carcinoma, Hepatocellular; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Concanavalin A; Cycloheximide; Epithelial Cells; Epithelium; Fibroblasts; Lectins; Liver; Liver Neoplasms; Neoplasm Proteins; Peptide Hydrolases; Protein Biosynthesis; Proteins; Rats; Surface Properties | 1973 |
Effect of metabolic inhibitors on the agglutination of tumor cells by concanavalin A and Ricinus communis agglutinin.
Topics: Agglutination; Animals; Azides; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Membrane; Cells; Concanavalin A; Cycloheximide; Cytochalasin B; Dimethyl Sulfoxide; Dinitrophenols; Glycosides; Lectins; Liver Neoplasms; Rats; Sarcoma, Yoshida; Temperature; Tritium | 1973 |
Phenylalanine hydroxylase in cultured hepatoxytes. I. Hormonal control of enzyme levels.
Topics: Animals; Blood; Butyrates; Carcinoma, Hepatocellular; Cell Line; Clone Cells; Corticosterone; Culture Media; Cyclic AMP; Cycloheximide; Dexamethasone; Glucocorticoids; Hydrocortisone; Liver; Liver Neoplasms; Neoplasm Proteins; Phenylalanine; Phenylalanine Hydroxylase; Rabbits; Rats; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tritium | 1973 |
Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Stimulation, Chemical; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1974 |
Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Cytidine; Deamination; Deoxyadenosines; Deoxyribonucleosides; Deoxyuridine; Diphosphates; Dipyridamole; DNA, Neoplasm; Guanine Nucleotides; Hydroxyurea; Hypoxanthines; Inosine; Inosine Nucleotides; Liver Neoplasms; Neoplasms, Experimental; Phosphates; Rats; RNA, Neoplasm; Thymidine; Time Factors; Tritium | 1974 |
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors | 1974 |
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; DNA, Neoplasm; Glutamine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleotides; Rats; Ribonucleotides; RNA, Neoplasm; Uridine | 1974 |
Ornithine decarboxylase turnover slowed by alpha-hydrazino-ornithine.
Topics: Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cycloheximide; Dithiothreitol; Dose-Response Relationship, Drug; Half-Life; Hydrazines; In Vitro Techniques; Kidney; Liver; Liver Neoplasms; Liver Regeneration; Nephrectomy; Ornithine; Pyridoxal Phosphate; Rats; Stimulation, Chemical; Time Factors | 1974 |
Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes.
Topics: Animals; Blood Proteins; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Gel; Cycloheximide; Drug Stability; Kinetics; Leucine; Liver Neoplasms; Neoplasm Proteins; Puromycin; Rabbits; Rats; Reticulocytes; Time Factors | 1974 |
Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.
Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; DNA, Neoplasm; Enzyme Activation; Histones; Hydroxyurea; Kinetics; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Thymidine; Tritium | 1974 |
Cholesteryl ester metabolism in tissue culture cells. I. Accumulation in Fu5AH rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cattle; Cell Line; Cholesterol; Cholesterol, Dietary; Chromatography, Gas; Columbidae; Culture Media; Cycloheximide; Dietary Fats; Drug Stability; Esters; Fibroblasts; Freezing; Haplorhini; Hot Temperature; Humans; Hyperlipidemias; L Cells; Lipoproteins; Liver Neoplasms; Mice; Neoplasms, Experimental; Oils; Rabbits; Rats; Species Specificity; Time Factors | 1974 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.
Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Chromatography, Thin Layer; Coenzyme A; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Glutarates; Half-Life; Kinetics; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Microsomes; Neoplasms, Experimental; Rats; Time Factors; Tritium; Ultracentrifugation | 1974 |
Cycloheximide inhibition of hypoxanthine transport cultured cells.
Topics: Adenine; Aminoisobutyric Acids; Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Epithelium; Hypoxanthines; Kinetics; Leucine; Liver Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pentosyltransferases; Puromycin; Rats; Sarcoma, Experimental; Time Factors | 1974 |
Acinomycin D and purine transport in cultured rat hepatoma cells.
Topics: Adenine; Animals; Biological Transport, Active; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Culture Media; Cycloheximide; Dactinomycin; Guanine; Guanosine; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Pentosyltransferases; Purines; Rats | 1974 |
Release of cytoplasmic enzymes into culture fluid.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyribonucleases; Fibroblasts; Glucuronidase; HeLa Cells; Humans; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Rats; Ribonucleases | 1974 |
Inhibition of cell growth and of purine biosynthesis by allopurinol and 4-aminopyrazolo(3,4-d)pyrimidine--a comparative study.
Topics: Allopurinol; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Clone Cells; Culture Media; Cycloheximide; Glycine; Growth; Hypoxanthines; In Vitro Techniques; Indicators and Reagents; Kinetics; Liver Neoplasms; Male; Pentosyltransferases; Purines; Pyrazoles; Pyrimidines; Rats; Ribonucleotides; Tritium; Xanthine Oxidase | 1974 |
Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.
Topics: Aldosterone; Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycloheximide; Dactinomycin; Desoxycorticosterone; Dexamethasone; Diethylstilbestrol; Enzyme Induction; Estradiol; Hydrocortisone; Leucine; Liver Neoplasms; Mitomycins; Progesterone; Puromycin; Rats; Steroids; Testosterone; Transaminases; Triamcinolone; Tyrosine Transaminase | 1966 |
Induction of tyrosine aminotransferase by D-glucosamine in rat hepatoma cell culture.
Topics: Animals; Carcinoma, Hepatocellular; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Glucosamine; Glucose; Liver Neoplasms; Proteins; Rats; Tyrosine Transaminase; Ultrasonics | 1969 |
Control of specific gene expression examined in synchronized mammalian cells.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Enzyme Repression; Genes, Regulator; Genetic Code; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Time; Tyrosine Transaminase | 1969 |
Control of degradation and synthesis of induced tyrosine aminotransferase studied in hepatoma cells in culture.
Topics: Carcinoma, Hepatocellular; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Enzyme Induction; Hydrocortisone; Leucine; Liver Neoplasms; Neoplasms, Experimental; Tritium; Tyrosine Transaminase | 1969 |
Posttranscriptional control of tyrosine aminotransferase synthesis by insulin.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Dexamethasone; Genetic Code; Insulin; Liver Neoplasms; Rats; Serum Albumin, Bovine; Tyrosine Transaminase | 1970 |
Induction of tyrosine aminotransferase by dibutyryl cyclic-AMP employing hepatoma cells in tissue culture.
Topics: Adenine Nucleotides; Carcinoma, Hepatocellular; Cell Line; Culture Media; Culture Techniques; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glucagon; Hydrocortisone; Insulin; Liver Neoplasms; RNA, Messenger; RNA, Neoplasm; Time Factors; Tyrosine Transaminase | 1971 |
Turnover of tyrosine transaminase in cultured hepatoma cells after inhibition of protein synthesis.
Topics: Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Enzyme Induction; Half-Life; Hydrocortisone; Immunochemistry; Kinetics; Leucine; Liver Neoplasms; Neoplasm Proteins; Puromycin; Time Factors; Tritium; Tyrosine Transaminase | 1971 |
The regulation of tyrosine aminotransferase synthesis. Studies in HTC cells with inhibitors of ribonucleic acid synthesis.
Topics: Benzimidazoles; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Drug Antagonism; Kinetics; Leucine; Liver Neoplasms; Metabolism; Neoplasm Proteins; Phosphates; Phosphorus Isotopes; Pyridines; RNA, Neoplasm; Sulfhydryl Compounds; Templates, Genetic; Tritium; Tyrosine Transaminase; Uridine | 1971 |
Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. I. Effects of glucocorticoids, N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate and insulin in Reuber H35 cells.
Topics: Antibody Formation; Butyrates; Carboxy-Lyases; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media; Cyclic AMP; Cycloheximide; Dexamethasone; Drug Interactions; Enzyme Induction; Glucagon; Humans; Hydrocortisone; Insulin; Isoproterenol; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phosphoenolpyruvate; Progesterone; Stimulation, Chemical; Time Factors; Tritium; Tyrosine Transaminase | 1971 |
Expression of differentiated functions in hepatoma cell hybrids: reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fusion; Cell Line; Cells, Cultured; Chromosomes; Clone Cells; Crosses, Genetic; Cycloheximide; Dactinomycin; Depression, Chemical; Dexamethasone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Epithelium; Hot Temperature; Hybrid Cells; In Vitro Techniques; Karyotyping; Liver; Liver Neoplasms; Rats; Tyrosine Transaminase | 1971 |
Regulation of tyrosine- -ketoglutarate transaminase in rat liver.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Induction; Fluorine; Half-Life; Hydrocortisone; Immunodiffusion; Insulin; Keto Acids; Kinetics; Leucine; Liver Neoplasms; Rats; Serine; Stereoisomerism; Tritium; Tyrosine Transaminase | 1971 |
D-glucose suppression of tyrosine aminotransferase in rat-hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media; Cycloheximide; Dactinomycin; Enzyme Induction; Glucosamine; Glucose; Hexoses; In Vitro Techniques; Lactose; Liver Neoplasms; Mannitol; Rats; Stereoisomerism; Tyrosine; Tyrosine Transaminase | 1971 |
Induction of tyrosine aminotransferase with N 6 ,O 2 -dibutyryl adenosine 3'-5'monophosphate in rat-hepatoma cells grown in culture.
Topics: Animals; Butyrates; Carcinoma, Hepatocellular; Cells, Cultured; Culture Media; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glucose; Hydrocortisone; In Vitro Techniques; Liver Neoplasms; Rats; Tyrosine; Tyrosine Transaminase | 1971 |
Effect of growth conditions on the ornithine decarboxylase activity of rat hepatoma cells.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Liver Neoplasms; Ornithine; Rats; Tyrosine Transaminase | 1971 |
Induction of tyrosine aminotransferase in HTC cells by N 6 , O 2' -dibutyryl adenosine 3', 5'-monophosphate.
Topics: Amino Acids; Animals; Butyrates; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cyclic AMP; Cycloheximide; Enzyme Induction; In Vitro Techniques; Liver Neoplasms; Rats; Tyrosine Transaminase | 1972 |
Expression of aryl hydrocarbon hydroxylase induction and suppression of tyrosine aminotransferase induction in somatic-cell hybrids.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Enzyme Induction; Fibroblasts; Hybrid Cells; Karyotyping; Kinetics; Liver Neoplasms; Methods; Mice; Mixed Function Oxygenases; Neoplasms, Experimental; Rats; Tyrosine Transaminase | 1972 |
Degradation of messenger RNA in mammalian cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Dactinomycin; Depression, Chemical; Enzyme Induction; Half-Life; Hydrocortisone; Leucine; Liver; Liver Neoplasms; Methods; Molecular Biology; Protein Biosynthesis; Puromycin; Radioimmunoassay; Rats; Ribosomes; RNA, Messenger; Time Factors; Tyrosine Transaminase | 1972 |