cycloheximide has been researched along with Cancer of Prostate in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.00) | 18.7374 |
| 1990's | 16 (26.67) | 18.2507 |
| 2000's | 31 (51.67) | 29.6817 |
| 2010's | 10 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbaskhan, A; Choudhary, MI; Ismail, M; Lajis, NH; Sattar, SA; Shaari, K | 1 |
| He, Y; Hwang, DJ; McEwan, IJ; Miller, DD; Mohler, ML; Narayanan, R; Ponnusamy, S; Thiyagarajan, T | 1 |
| Addo, EM; Anaya-Eugenio, GD; Carcache de Blanco, EJ; Ezzone, N; Henkin, JM; Kinghorn, AD; Ninh, TN; Ren, Y; Soejarto, DD | 1 |
| Cao, QQ; Dong, YF; Gu, X; Li, W; Liao, K; Liu, BD; Liu, Y; Wan, ZJ; Zhu, Q | 1 |
| Alaisami, R; Bollag, WB; Choudhary, V; Kaddour-Djebbar, I; Kumar, MV | 1 |
| Chang, JL; Cheng, CW; Chien, MH; Chow, JM; Hsiao, M; Lai, GM; Lee, LM; Lee, WJ; Lin, YW; Wen, YC | 1 |
| Bharti, S; Bhujwalla, ZM; Danhier, P; Kakkad, S; Krishnamachary, B; Mironchik, Y | 1 |
| Lazari, MF; Lombardi, AP; Lucas, TF; Pisolato, R; Porto, CS; Vicente, CM | 1 |
| Kim, MH; Thomas, R | 1 |
| Brill, A; Dashevsky, O; Varon, D | 1 |
| Brogley, M; Chinnaiyan, A; Dhanasekaran, S; Hofer, MD; Kuefer, R; Lapensee, EW; O'Mahony, OA; Pienta, KJ; Rehman, H; Robins, DM; Rubin, MA; Steinkamp, MP | 1 |
| Aiying, W; Anli, J; Nana, N; Pengju, Z; Qingwei, L; Weiwen, C; Zhaobo, C; Zhaoqin, H | 1 |
| Kai, L; Levenson, AS | 1 |
| Fujinami, K; Ishiguro, H; Kubota, Y; Uemura, H | 1 |
| Kurland, JF; McDonnell, TJ; Meyn, RE; Munshi, A; Sah, NK; Su, B | 1 |
| Lou, YR; Nazarova, N; Pennanen, P; Qiao, S; Tuohimaa, P | 1 |
| Jiang, F; Wang, Z | 1 |
| Chuan, YC; Flores-Morales, A; Nordstedt, G; Pang, ST; Pousette, A; Skoog, L | 1 |
| DeWolf, WC; Jin, TG; Khosravi-Far, R; Olumi, AF; Yang, H; Zhang, X | 1 |
| Lou, YR; Nazarova, N; Talonpoika, R; Tuohimaa, P | 1 |
| Jaruga-Killeen, E; Rayford, W | 1 |
| Cinar, B; De Benedetti, A; Freeman, MR | 1 |
| Bremer, E; George, D; Li, H; Monroe, J; Yang, W; Zhang, Y | 1 |
| Dong, Z; Lu, S | 1 |
| Abbas Rizvi, SM; Allen, BJ; Apostolidis, C; Li, Y; Morgenstern, A; Qu, CF; Raja, C; Song, EY | 1 |
| Chiao, JW; Liu, XM; Wang, LG | 1 |
| Amin, M; Anderson, C; Arnold, RS; Chung, LW; Johnstone, P; Konaka, H; Kubo, H; Logani, S; Marshall, FF; Mousses, S; Nakagawa, M; Petros, JA; Shigemura, K; Sung, SY; Wang, R; Zhau, HE | 1 |
| Arasheben, A; Barski, A; Coetzee, GA; Cogan, JP; Frenkel, B; Jariwala, U; Jia, L; Neilson, JJ; Pregizer, S; Prescott, J; Shen, HC | 1 |
| Boon-Unge, K; Govitrapong, P; Yu, Q; Zhou, A; Zhou, J; Zou, T | 1 |
| Costello, LC; Feng, P; Franklin, RB; Guan, Z; Li, T | 1 |
| Gorospe, M; Kawai, T; Otto, K; Rinker-Schaeffer, CW; Robinson, VL; Shalhav, O | 1 |
| Cousins, RJ; Giles, PJ | 1 |
| Esquenet, M; Heyns, W; Rombauts, W; Swinnen, JV; Verhoeven, G | 1 |
| Borner, MM; Myers, CE; Sartor, O; Schneider, E; Sei, Y; Toko, T; Trepel, JB | 1 |
| Borner, MM; Myers, CE; Pirnia, F; Sartor, O; Schneider, E; Trepel, JB | 1 |
| Burnstein, KL; Dai, JL | 1 |
| Dahiya, R; Hughes-Fulford, M; Tjandrawinata, RR | 1 |
| Bishop, GA; Cohen, MB; Glover, RA; Hostager, BS; Kiefer, MC; Pavloff, N; Rokhlin, OW; Sidorenko, SP; Umansky, SR; Waldschmidt, TJ | 1 |
| De Nayer, P; Gala, JL; Hanon, F; Heusterspreute, M; Loric, S; Philippe, M; Tombal, B; Van Cangh, P | 1 |
| Sehgal, I; Thompson, TC | 1 |
| Feldman, D; Ly, LH; Peehl, DM; Zhao, XY | 1 |
| Fan, Z; Mendelsohn, J; Ye, D | 1 |
| Heyns, W; Swinnen, JV; Ulrix, W; Verhoeven, G | 1 |
| Cohen, MB; Gewies, A; Rokhlin, OW | 2 |
| Tanabe, T | 1 |
| Choi, SH; Chun, BG; Chun, YS; Kang, H; Kang, SW; Min, BH; Park, IS; Shin, KH | 1 |
| Brady, HP; Coffey, RN; Fitzpatrick, JM; Gibbons, NB; Watson, RW | 1 |
| Honda, T; Li, Y; McDonnell, TJ; Meyn, RE; Munshi, A; Pappas, G; Younes, A | 1 |
| Ficazzola, MA; Fraiman, M; Gitlin, J; Melamed, J; Rubin, MA; Walden, PD; Woo, K | 1 |
| Fillion, C; Fournier, A; Grenier, J; Labrie, C; Labrie, Y; Qi, H | 1 |
| Bonham, MJ; Chipuk, JE; Cornelius, SC; Danielpour, D; Jorgensen, JS; Kim, SJ; Pultz, NJ | 1 |
| Melamud, O; Peehl, DM; Pei, D; Sellers, RG; Wiehr, C; Wilson, MJ | 1 |
| Bern, MM; Bing, DH; Spurlock, SE | 1 |
| Henttu, P; Vihko, P | 1 |
| Bang, YJ; Danielpour, D; Kim, KY; Kim, SJ; Myers, CE; O'Reilly, MA; Trepel, JB | 1 |
| Baulieu, EE; Mercier-Bodard, C; Nivet, V | 1 |
| Andrews, PE; Bilhartz, DL; Montgomery, BT; Qui, SD; Tindall, DJ; Young, CY | 1 |
| Colletta, AA; Kealey, T | 1 |
| Lerner, S; Nag, A; Norris, JS; Smith, RG; Syms, AJ | 1 |
60 other study(ies) available for cycloheximide and Cancer of Prostate
| Article | Year |
|---|---|
cis-Clerodane-type furanoditerpenoids from Tinospora crispa.
Topics: 3T3 Cells; Animals; Diterpenes, Clerodane; Drug Screening Assays, Antitumor; Humans; Malaysia; Male; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Prostatic Neoplasms; Stereoisomerism; Tinospora | 2010 |
New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity.
Topics: Amides; Androgen Receptor Antagonists; Androgens; Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Humans; Indoles; Male; Mice; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Proteolysis; Rats; Receptors, Androgen; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2019 |
Caspase-Dependent Apoptosis in Prostate Cancer Cells and Zebrafish by Corchorusoside C from Streptocaulon juventas.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apocynaceae; Apoptosis; Caspases; Cell Line, Tumor; Humans; I-kappa B Kinase; Male; Molecular Structure; Poly (ADP-Ribose) Polymerase-1; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrans; Vietnam; Zebrafish | 2019 |
Alteration of Androgen Receptor Protein Stability by Triptolide in LNCaP Cells.
Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Calpain; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Diterpenes; Epoxy Compounds; Humans; Male; Phenanthrenes; Prostatic Neoplasms; Protein Stability; Receptors, Androgen | 2018 |
Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: a role in apoptosis in prostate cancer cells.
Topics: Apoptosis; Calcium; Cell Line, Tumor; Clonazepam; Cycloheximide; GTP Phosphohydrolases; Humans; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Signal Transduction; Thiazepines; Ubiquitination | 2014 |
Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Cycloheximide; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Immunohistochemistry; Male; Mice; Mice, SCID; Microtubule-Associated Proteins; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transcription Factor CHOP; Transplantation, Heterologous; Vacuoles | 2015 |
Combining Optical Reporter Proteins with Different Half-lives to Detect Temporal Evolution of Hypoxia and Reoxygenation in Tumors.
Topics: Animals; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cycloheximide; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; Luminescent Proteins; Male; Mice, Nude; Microscopy, Fluorescence; Oxygen; Prostatic Neoplasms; Protein Synthesis Inhibitors; Red Fluorescent Protein; Response Elements; Time-Lapse Imaging; Transplantation, Heterologous | 2015 |
Estrogen receptor beta (ERβ) mediates expression of β-catenin and proliferation in prostate cancer cell line PC-3.
Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin D2; Cycloheximide; Estradiol; Estrogen Receptor beta; Humans; Male; Nitriles; Phenols; Phosphorylation; Prostatic Neoplasms; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Thymidine | 2016 |
HIF-1 alpha: a key survival factor for serum-deprived prostate cancer cells.
Topics: Adenocarcinoma; Antibodies; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cycloheximide; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin-Like Growth Factor II; Male; Prostatic Neoplasms; Protein Synthesis Inhibitors; RNA, Small Interfering; Serum Albumin, Bovine; Up-Regulation; Vascular Endothelial Growth Factor A | 2008 |
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.
Topics: Blood Platelets; Cell Adhesion; Cell Culture Techniques; Cycloheximide; Cytoplasm; Dactinomycin; Gelatin; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 2; Prostatic Neoplasms; Protein Synthesis Inhibitors; Time Factors; Up-Regulation | 2009 |
Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy.
Topics: Amino Acid Substitution; Anilides; Antineoplastic Agents; Autopsy; Cycloheximide; DNA Primers; Flutamide; Humans; Lymphatic Metastasis; Male; Mutation; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tosyl Compounds | 2009 |
NKX3.1 potentiates TNF-alpha/CHX-induced apoptosis of prostate cancer cells through increasing caspase-3 expression and its activity.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cycloheximide; Homeodomain Proteins; Humans; Male; Prostatic Neoplasms; Transcription Factors; Tumor Necrosis Factor-alpha | 2010 |
Combination of resveratrol and antiandrogen flutamide has synergistic effect on androgen receptor inhibition in prostate cancer cells.
Topics: Androgen Antagonists; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Dihydrotestosterone; Down-Regulation; Drug Synergism; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Receptors, Androgen; Resveratrol; RNA, Messenger; Stilbenes; Transcriptional Activation | 2011 |
Liprin-alpha2 gene, protein tyrosine phosphatase LAR interacting protein related gene, is downregulated by androgens in the human prostate cancer cell line LNCaP.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Androgens; Cycloheximide; Dihydrotestosterone; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Proteins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2002 |
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
Topics: Activating Transcription Factor 2; Anisomycin; Apoptosis; Apoptosis Regulatory Proteins; Curcumin; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Peptide Fragments; Prostatic Neoplasms; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cells.
Topics: Androgen Antagonists; Anilides; Calcitriol; Cerulenin; Cycloheximide; Down-Regulation; Enzyme Inhibitors; Fatty Acid Synthases; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured | 2003 |
Gadd45gamma is androgen-responsive and growth-inhibitory in prostate cancer cells.
Topics: Androgens; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Size; Cycloheximide; GADD45 Proteins; Humans; Intracellular Signaling Peptides and Proteins; Male; Prostatic Neoplasms; Protein Biosynthesis; Proteins; Up-Regulation | 2004 |
Regulation of matrix metalloproteinase 13 expression by androgen in prostate cancer.
Topics: Androgen Antagonists; Androgens; Anilides; Collagenases; Cycloheximide; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Male; Matrix Metalloproteinase 13; Nitriles; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured | 2004 |
Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cycloheximide; Drug Resistance, Neoplasm; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Glycoproteins; Prostatic Neoplasms; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2004 |
5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Calcitriol; Cycloheximide; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Drug Interactions; Flutamide; Gene Expression Regulation, Enzymologic; Humans; Male; Nitriles; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Tosyl Compounds; Tumor Cells, Cultured; Vitamin D3 24-Hydroxylase | 2005 |
TNF receptor 1 is involved in the induction of apoptosis by the cyclin dependent kinase inhibitor p27Kip1 in the prostate cancer cell line PC-3.
Topics: Adenoviridae; Amino Acid Chloromethyl Ketones; Antibodies; Apoptosis; Carrier Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Cycloheximide; DNA Fragmentation; Genetic Vectors; Humans; Intracellular Signaling Peptides and Proteins; Male; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Transduction, Genetic | 2005 |
Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin.
Topics: Androgen Receptor Antagonists; Cell Line, Tumor; Cycloheximide; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Male; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Protein Biosynthesis; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Androgen; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Transcription, Genetic; Transcriptional Activation; Transfection | 2005 |
Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Autophagy; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cycloheximide; Cysteine Proteinase Inhibitors; Cytokines; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Intercellular Signaling Peptides and Proteins; Leupeptins; Male; Microscopy, Electron; Molecular Chaperones; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Synthesis Inhibitors; Signal Transduction | 2006 |
Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells.
Topics: Activin Receptors, Type I; Blotting, Western; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Male; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Preclinical studies of bismuth-213 labeled plasminogen activator inhibitor type 2 (PAI2) in a prostate cancer nude mouse xenograft model.
Topics: Animals; Bismuth; Chelating Agents; Cycloheximide; Humans; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pentetic Acid; Plasminogen Activator Inhibitor 2; Prostatic Neoplasms; Rabbits; Radioisotopes; Serine Proteinase Inhibitors | 2006 |
Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate.
Topics: Androgen Receptor Antagonists; Anticarcinogenic Agents; Cell Line, Tumor; Cycloheximide; Humans; Isothiocyanates; Leupeptins; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Sp1 Transcription Factor; Transcription, Genetic | 2006 |
Oxidative stress induces ADAM9 protein expression in human prostate cancer cells.
Topics: ADAM Proteins; Adenocarcinoma; Androgens; Antioxidants; Apoptosis; Azoles; Catalase; Cell Hypoxia; Cell Line, Tumor; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydrogen Peroxide; Isoindoles; Male; Membrane Proteins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Organoselenium Compounds; Oxidative Stress; Prostatic Neoplasms; Reactive Oxygen Species | 2006 |
Androgen receptor-mediated repression of novel target genes.
Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Cycloheximide; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptor, Muscarinic M1; Receptors, Androgen; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tosyl Compounds; Transfection | 2007 |
Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.
Topics: Alternative Splicing; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Down-Regulation; Emetine; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Marine Toxins; Okadaic Acid; Oxazoles; Prostatic Neoplasms; Protein Phosphatase 1; Protein Phosphatase 2; Up-Regulation; Uterine Cervical Neoplasms | 2007 |
The involvement of Bax in zinc-induced mitochondrial apoptogenesis in malignant prostate cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cycloheximide; Humans; Male; Mitochondria; Models, Biological; Prostatic Neoplasms; Protein Binding; Zinc | 2008 |
Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
Topics: Acetylcysteine; Blotting, Northern; Cell Line, Tumor; Cycloheximide; Dactinomycin; Ethanol; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; Neoplasm Metastasis; Ovarian Neoplasms; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Biosynthesis | 2008 |
Hormonal regulation of zinc metabolism in a human prostatic carcinoma cell line (PC-3).
Topics: Adenocarcinoma; Cell Line; Cycloheximide; Cystine; Dexamethasone; Dihydrotestosterone; Hormones; Humans; Insulin; Kinetics; Male; Metallothionein; Prostaglandins E; Prostatic Neoplasms; Zinc | 1982 |
Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the human prostatic adenocarcinoma cell line LNCaP.
Topics: Adenocarcinoma; Androgens; Blotting, Northern; Carrier Proteins; Cloning, Molecular; Cycloheximide; Diazepam Binding Inhibitor; Dihydrotestosterone; DNA, Complementary; Humans; Immune Sera; Male; Metribolone; Nandrolone; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Testosterone; Tumor Cells, Cultured | 1994 |
Drug-induced apoptosis is not necessarily dependent on macromolecular synthesis or proliferation in the p53-negative human prostate cancer cell line PC-3.
Topics: Antineoplastic Agents; Aphidicolin; Apoptosis; Cell Cycle; Cell Division; Cycloheximide; DNA, Neoplasm; Humans; Lovastatin; Male; Microscopy, Electron; Nucleosomes; Prostatic Neoplasms; Tumor Cells, Cultured | 1995 |
The detergent Triton X-100 induces a death pattern in human carcinoma cell lines that resembles cytotoxic lymphocyte-induced apoptosis.
Topics: Apoptosis; Calcium; Cell Death; Colonic Neoplasms; Cycloheximide; DNA, Neoplasm; Humans; Kinetics; Male; Octoxynol; Prostatic Neoplasms; Protein Biosynthesis; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1994 |
Two androgen response elements in the androgen receptor coding region are required for cell-specific up-regulation of receptor messenger RNA.
Topics: Androgens; Base Sequence; Binding Sites; Cycloheximide; Dactinomycin; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Kinetics; Male; Metribolone; Molecular Sequence Data; Organ Specificity; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptors, Androgen; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation | 1996 |
Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells.
Topics: 16,16-Dimethylprostaglandin E2; Anti-Ulcer Agents; Breast Neoplasms; Cell Count; Cell Division; Cycloheximide; Cyclooxygenase 2; DNA Replication; DNA, Neoplasm; Enzyme Induction; Female; Flurbiprofen; Humans; Isoenzymes; Male; Membrane Proteins; Ovarian Neoplasms; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1997 |
Fas-mediated apoptosis in human prostatic carcinoma cell lines.
Topics: Antigen-Antibody Reactions; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; CD40 Antigens; Cell Division; Cycloheximide; DNA Fragmentation; fas Receptor; Flow Cytometry; Humans; Male; Phosphotyrosine; Prostatic Neoplasms; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1997 |
Expression of prostate-specific antigen and prostate-specific membrane antigen transcripts in blood cells: implications for the detection of hematogenous prostate cells and standardization.
Topics: Adult; Aged; Animals; Antigens, Surface; Blood Cells; Breast Neoplasms; Carboxypeptidases; Cell Line; Cell Line, Transformed; CHO Cells; Cricetinae; Cycloheximide; DNA Primers; Exons; Female; Glutamate Carboxypeptidase II; Heterozygote; Humans; Jurkat Cells; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Recombinant Proteins; Sensitivity and Specificity; Stochastic Processes; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-beta1 in human prostate cancer cell lines.
Topics: Collagenases; Cycloheximide; Dactinomycin; Gelatinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Nucleic Acid Synthesis Inhibitors; Prostatic Neoplasms; Protein Synthesis Inhibitors; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Transcriptional Activation; Transforming Growth Factor beta; Tumor Cells, Cultured | 1999 |
Induction of androgen receptor by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in LNCaP human prostate cancer cells.
Topics: Alitretinoin; Calcitriol; Cell Division; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptors, Androgen; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1999 |
Androgen and epidermal growth factor down-regulate cyclin-dependent kinase inhibitor p27Kip1 and costimulate proliferation of MDA PCa 2a and MDA PCa 2b prostate cancer cells.
Topics: Androgen Antagonists; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cycloheximide; Dihydrotestosterone; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flutamide; Humans; Male; Metribolone; Microtubule-Associated Proteins; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptors, Androgen; Testosterone Congeners; Trastuzumab; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1999 |
Androgens down-regulate the expression of the human homologue of paternally expressed gene-3 in the prostatic adenocarcinoma cell line LNCaP.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Kruppel-Like Transcription Factors; Male; Metribolone; Mice; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinases; Proteins; Receptors, Androgen; RNA, Messenger; Testosterone Congeners; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Zinc Fingers | 1999 |
Cytochrome c is involved in Fas-mediated apoptosis of prostatic carcinoma cell lines.
Topics: Antibodies, Monoclonal; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspases; Cell Nucleus; Cycloheximide; Cytochrome c Group; Cytoplasm; DNA Fragmentation; Enzyme Activation; fas Receptor; Humans; Male; Mitochondria; Prostatic Neoplasms; Tumor Cells, Cultured | 2000 |
Effects of N-(4-hydroxyphenyl) retinamide on urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in prostate adenocarcinoma cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Cycloheximide; Fenretinide; Gene Expression; Humans; Male; Plasminogen Activator Inhibitor 1; Prostatic Neoplasms; Protein Synthesis Inhibitors; RNA Stability; RNA, Messenger; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2000 |
Ceramide induces cell death in the human prostatic carcinoma cell lines PC3 and DU145 but does not seem to be involved in Fas-mediated apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Ceramides; Cycloheximide; fas Receptor; Humans; Male; Prostatic Neoplasms; Sphingomyelins; Tumor Cells, Cultured | 2000 |
Cytoprotective effect of arginine deiminase on taxol-induced apoptosis in DU145 human prostate cancer cells.
Topics: Amino Acid Sequence; Animals; Apoptosis; Arginine; Astrocytes; Cell Line; Culture Media, Conditioned; Cycloheximide; Cytoprotection; DNA Fragmentation; G1 Phase; Humans; Hydrolases; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; Molecular Sequence Data; Nitric Oxide; Paclitaxel; Prostatic Neoplasms; Protein Synthesis Inhibitors; Rats; Sequence Alignment; Sertoli Cells; Tumor Cells, Cultured | 2000 |
Heat-shock proteins inhibit induction of prostate cancer cell apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Blotting, Western; Cycloheximide; Etoposide; Glutathione; Glutathione Transferase; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Kinetics; Male; Maleates; Molecular Chaperones; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nucleic Acid Synthesis Inhibitors; Prostatic Neoplasms; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Tumor Cells, Cultured | 2000 |
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Cycloheximide; Cytochrome c Group; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Male; Membrane Glycoproteins; Prostatic Neoplasms; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Antiproliferative B cell translocation gene 2 protein is down-regulated post-transcriptionally as an early event in prostate carcinogenesis.
Topics: Androgens; Cell Division; Cell Transformation, Neoplastic; Cycloheximide; Cysteine Endopeptidases; Down-Regulation; Genes, Tumor Suppressor; Humans; Hydrolysis; Immediate-Early Proteins; Immunohistochemistry; Male; Multienzyme Complexes; Mutagens; Prostatic Neoplasms; Proteasome Endopeptidase Complex; RNA Processing, Post-Transcriptional; RNA, Messenger; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitins | 2001 |
Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Breast Neoplasms; Cloning, Molecular; Cycloheximide; DNA, Complementary; Female; Gene Expression Profiling; Humans; Male; Metribolone; Molecular Sequence Data; Prostatic Neoplasms; Protein Serine-Threonine Kinases; RNA, Messenger; Testosterone Congeners; Time Factors; Tumor Cells, Cultured; Up-Regulation | 2001 |
The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.
Topics: Adenocarcinoma; Cycloheximide; Dactinomycin; Dihydrotestosterone; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, Reporter; Humans; Immediate-Early Proteins; Ligands; Male; Metribolone; Prostatic Neoplasms; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Receptors, Androgen; Signal Transduction; Smad3 Protein; Testosterone Congeners; Trans-Activators; Transcription Factors; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured | 2002 |
Expression of matrix metalloproteinase-2 and -9 and their inhibitors, tissue inhibitor of metalloproteinase-1 and -2, in primary cultures of human prostatic stromal and epithelial cells.
Topics: Cycloheximide; Dactinomycin; Epithelial Cells; Gene Expression Regulation, Neoplastic; Growth Substances; Hormones; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Nucleic Acid Synthesis Inhibitors; Prostate; Prostatic Neoplasms; Protein Synthesis Inhibitors; RNA, Messenger; Stromal Cells; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Tumor Cells, Cultured | 2002 |
Synthesis of the first component of complement by primary cultures of human tumors of the colon and urogenital tract and comparable normal tissue.
Topics: Adenoma; Carcinoma; Carcinoma, Transitional Cell; Cell Survival; Cells, Cultured; Chromatography, Affinity; Colon; Colonic Neoplasms; Complement C1; Complement C1 Inactivator Proteins; Complement System Proteins; Cycloheximide; Epithelial Cells; Epithelium; Esterases; Humans; Male; Mucous Membrane; Prostatic Neoplasms; Urinary Bladder; Urinary Bladder Neoplasms | 1975 |
Steroids inversely affect the biosynthesis and secretion of human prostatic acid phosphatase and prostate-specific antigen in the LNCaP cell line.
Topics: Acid Phosphatase; Antigens, Neoplasm; Biomarkers, Tumor; Cell Line; Cycloheximide; Estradiol; Humans; Kinetics; Male; Metribolone; Pregnenediones; Progesterone; Progesterone Congeners; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3.
Topics: 1-Methyl-3-isobutylxanthine; Aprotinin; Blotting, Northern; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leupeptins; Male; Pentoxifylline; Phenylmethylsulfonyl Fluoride; Prostatic Neoplasms; RNA, Neoplasm; Theophylline; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Effects of hormones on SBP mRNA levels in human cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cycloheximide; Endometrial Neoplasms; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Insulin; Liver Neoplasms; Male; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Sex Hormone-Binding Globulin; Steroids; Triiodothyronine; Tumor Cells, Cultured | 1991 |
Hormonal regulation of prostate-specific antigen messenger RNA in human prostatic adenocarcinoma cell line LNCaP.
Topics: Adenocarcinoma; Androgens; Antigens, Neoplasm; Base Sequence; Cycloheximide; DNA; Gene Expression Regulation; Hormones; Humans; Male; Molecular Sequence Data; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured | 1991 |
cDNA cloning of a human androgen-induced mRNA exhibiting an early and protein synthesis-independent induction.
Topics: Androgens; Blotting, Northern; Cloning, Molecular; Cycloheximide; Dactinomycin; DNA; Gene Expression; Humans; Kinetics; Male; Prostatic Neoplasms; Puromycin; RNA, Messenger; Tumor Cells, Cultured | 1991 |
Mechanism of the glucocorticoid regulation of growth of the androgen-sensitive prostate-derived R3327H-G8-A1 tumor cell line.
Topics: Adenocarcinoma; Androgens; Animals; Blood; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dihydrotestosterone; Epidermal Growth Factor; Estrenes; Glucocorticoids; Interphase; Kinetics; Male; Metribolone; Platelet-Derived Growth Factor; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Glucocorticoid; Triamcinolone Acetonide | 1985 |