cycloheximide has been researched along with Breast Neoplasms in 170 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (17.65) | 18.7374 |
1990's | 79 (46.47) | 18.2507 |
2000's | 46 (27.06) | 29.6817 |
2010's | 12 (7.06) | 24.3611 |
2020's | 3 (1.76) | 2.80 |
Authors | Studies |
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Dunbar, DC; Jones, DK; Kim, YP; Mohammed, KA; Muhammad, I; Nagle, DG; Zhou, YD | 1 |
Du, L; Jekabsons, MB; Li, J; Mahdi, F; Nagle, DG; Zhou, YD | 1 |
Appleman, JR; Chen, J; Chiang, GG; Clarine, J; Eam, B; Ernst, JT; Fish, S; Howard, H; Michels, T; Molter, J; Nevarez, A; Nilewski, C; Packard, G; Reich, SH; Sperry, S; Sprengeler, PA; Staunton, J; Thompson, PA; Tran, C; Webster, KR; Wegerski, CJ; Xiang, A; Young, NP | 1 |
Crown, J; Duffy, MJ; Tang, M | 1 |
Cuicui, L; Fei, X; Hongjia, F; Huan, F; Jialun, L; Jianpeng, X; Jie, W; Jiemin, W; Jing, F; Jing, L; Lin, Y; Lulu, W; Qiuju, W; Sha, L; Weiwei, Z; Ying, L; You, P; Zhaolin, M | 1 |
Dong, Y; Liu, Y; Luo, J; Su, L; Zhao, L | 1 |
Koirala, S; Thomas, LN; Too, CK | 1 |
Gomez-Cambronero, J; Hatton, N; Henkels, KM; Lintz, E; Mahankali, M | 1 |
Cabrera, E; Freire, R; Gomes, AR; Gong, C; Karunarathna, U; Khongkow, P; Khoo, US; Kongsema, M; Lam, EW; Man, EP; Medema, RH; Tsang, JW; Zona, S | 1 |
Dong, M; Fan, D; Geng, P; Hou, P; Huang, B; Li, H; Li, Y; Li, Z; Liu, D; Lu, J; Ma, M; Mihretab, A; Wang, G; Yao, R; Zhang, Y | 1 |
Adams, BD; Claffey, KP; White, BA | 1 |
Dougherty, SM; Klinge, CM; Li, Y; Manavalan, TT; Riggs, KA; Wickramasinghe, NS | 1 |
Behera, MA; Dai, Q; Garde, R; Jungheim, E; Price, TM; Saner, C | 1 |
Choi, KS; Kim, EH; Kwon, TK; Lim, JH; Yoon, MJ | 1 |
Balapure, AK; Gupta, DK; Nigam, D; Nigam, M; Ranjan, V; Sharma, R; Singh, N; Sundaram, S; Zaidi, D | 1 |
Dong, JT; Dong, XY; Guo, P; Li, Q; Sun, X | 1 |
Armstrong, SR; Guo, B; Hembruff, SL; Kalatskaya, I; Lanner, C; Parissenti, AM; Reed, K; Sprowl, JA; Stein, L; Tam, A | 1 |
Bisoski, L; Buac, D; Cui, Q; Dou, QP; Kona, FR; Stark, K | 1 |
El Zowalaty, M; Ghrici, M; Ideris, A; Omar, AR | 1 |
Gudas, LJ; Liu, L | 1 |
Düssmann, H; Kögel, D; Prehn, JH; Rehm, M | 1 |
Banerjee, S; Banerjee, SK; Saxena, N; Sengupta, K | 1 |
Hall, JM; Korach, KS | 1 |
Abdelrahim, M; Burghardt, R; Safe, S; Saville, B; Stoner, M; Walker, K; Wormke, M | 1 |
Eng, C; Waite, KA | 1 |
Alaoui-Jamali, MA; Igdoura, SA; Laird, DW; Qin, H; Shao, Q | 1 |
Bernard-Gallon, DJ; Bignon, YJ; Vissac-Sabatier, C | 1 |
Edwards, EA; Fulthorpe, R; Liss, SN; Wang, DY | 1 |
Birnbaum, D; Cohen, PA; Danis, E; Duchesne, MJ; Magnino, F; Nguyen, C; Pinloche, S; Pons, M; Theillet, C; Vendrell, JA | 1 |
Benoit, V; Bours, V; Chariot, A; Delacroix, L; Deregowski, V; Jacobs, N; Merville, MP | 1 |
Hayashi, SI; Inoue, A; Kiyama, R; Omoto, Y; Yamaguchi, Y | 1 |
Gustafsson, JA; Kietz, S; Matthews, J; Pettersson, K; Ström, A; Thomsen, JS | 1 |
Hsieh, HY; Hsieh, YS; Huang, CY; Kuo, SJ; Liu, JY; Tsai, JH; Wu, TT; Yu, SY | 1 |
Body, JJ; Journé, F; Laurent, G; Leclercq, G; Nonclercq, D | 1 |
Bouadis, A; Halverson, D; Palmieri, D; Salerno, M; Steeg, PS | 1 |
Bingle, L; Fang, WG; Gong, LH; Heng, WJ; Li, Y; Shi, YH; Wang, YX | 1 |
Bohidar, HB; Sachin, K; Saxena, A; Verma, AK | 1 |
Journé, F; Laïos, I; Laurent, G; Leclercq, G; Nonclercq, D; Toillon, RA; Vidal, DS | 1 |
Pawlak, KJ; Wiebe, JP; Zhang, G | 1 |
Amlal, H; Balasubramaniam, A; Faroqui, S; Sheriff, S | 1 |
Harrington, WR; Katzenellenbogen, BS; Sengupta, S | 1 |
Cohen, MB; Guseva, NV; Rokhlin, OW; Taghiyev, AF | 1 |
Khan, S; Liu, S; Safe, S; Stoner, M | 1 |
Kuo, CC; Peng, ST; Shaw, CF; Su, CH; Wang, HS | 1 |
Ramana, CV; Rishi, AK; Wali, A; Zhang, L | 1 |
Boon-Unge, K; Govitrapong, P; Yu, Q; Zhou, A; Zhou, J; Zou, T | 1 |
Dickerman, HW; Kumar, SA; Ryan, TJ; Seeger, JI | 1 |
Brown, AM; Chambon, P; Jeltsch, JM; Roberts, M | 1 |
Fennessey, PV; Horwitz, KB; Mockus, MB; Pike, AW; Sheridan, RL | 1 |
Pezzino, V; Purrello, F; Trischitta, V; Vigneri, R | 1 |
Ballard, FJ | 1 |
Horwitz, KB; McGuire, WL | 1 |
Horwitz, KB; Lessey, BA; Mockus, MB | 1 |
Sato, H; Seiki, M; Thompson, EW; Yu, M | 1 |
Dickson, RB; Johnson, GR; Martínez-Lacaci, I; Normanno, N; Plowman, GD; Saceda, M; Salomon, DS | 1 |
Chen, JC; Clemmons, DR; Fontana, JA; Hussain, A; LeRoith, D; Roberts, CT; Shao, ZM; Sheikh, MS | 1 |
Hill, SM; Molis, TM; Spriggs, LL | 1 |
Chin, KV; Hait, WN; Yang, JM | 1 |
Dapunt, O; Daxenbichler, G; Marth, C; Widschwendter, M | 1 |
Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A; Malik, Z; Weiss, C | 1 |
Lessard, M; Poulin, R; Singh, SM; Zhao, C | 1 |
Larsson, O; Zetterberg, A | 1 |
Keski-Oja, J; Koli, K | 1 |
Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A; Malik, Z | 1 |
Garach-Jehoshua, O; Koren, R; Liberman, UA; Ravid, A; Rocker, D | 1 |
Cook, JA; Fisher, J; Liebmann, J; Mitchell, JB; Teague, D | 1 |
López-Boado, YS; López-Otín, C; Tolivia, J | 1 |
Furukawa, Y; Hayashi, K; Hirota, M; Miyashita, S; Shiroyama, C; Yamamoto, T | 1 |
Duncan, LJ; Parker, MG; Rea, D; Reed, MJ | 1 |
Gol-Winkler, R; Grooteclaes, M; Pasleau, F | 1 |
Kaur, G; Sartor, O; Sausville, EA; Sebers, S; Stetler-Stevenson, M; Worland, PJ | 1 |
Krishnan, V; Narasimhan, TR; Porter, W; Safe, S; Wang, X | 1 |
Chen, JC; Fontana, JA; Shao, ZM; Sheikh, MS | 1 |
Kelly, PA; Lee, CS; Ormandy, CJ; Sutherland, RL | 1 |
Lindsey, RK; Martin, MB; Saceda, M | 1 |
Arellano, LO; Safe, S; Wang, X | 1 |
Davidson, NE; Hahm, HA; Prestigiacomo, LJ | 1 |
Fujita, S; Inada, K; Matsuo, S; Nakashima, Y; Nomura, K; Ogawa, M; Saishoji, T; Takano, S; Yamashita, J; Yamashita, S | 1 |
Beery, R; Geier, A; Haimson, M; Hemi, R | 1 |
Borrás, M; el Khissiin, A; Laios, I; Leclercq, G; Legros, N; Lempereur, F; Seo, HS | 1 |
Chrysogelos, SA; El-Ashry, D; Lauber, AH; Yarden, RI | 1 |
Bianchini, E; Carsana, A; Costanzo, C; Faggioli, L; Furia, A; Merola, M; Palmieri, M | 1 |
Bar-Shalom, I; Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A; Lunenfeld, B; Malik, Z | 1 |
Bowcock, AM; Spillman, MA | 1 |
Audette, M; Charest-Gaudreault, R; Dionne, P; Gamache, I; Huber, M; Pelletier, JG; Poulin, R; Torossian, K | 1 |
Lunec, J; Nutt, JE | 1 |
el-Tanani, MK; Green, CD | 1 |
Bandoh, S; Maruyama, K; Ohkura, N; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A | 1 |
Dahiya, R; Hughes-Fulford, M; Tjandrawinata, RR | 1 |
Alvarez, S; Binderup, L; López-Boado, YS; López-Otín, C; Puente, XS; Tolivia, J | 1 |
Binder, C; Binder, L; Hiddemann, W; Kroemker, M; Schulz, M | 1 |
Borràs, M; Cleeren, A; El Khissiin, A; Leclercq, G | 1 |
De Nayer, P; Gala, JL; Hanon, F; Heusterspreute, M; Loric, S; Philippe, M; Tombal, B; Van Cangh, P | 1 |
Jaggi, R; Schaerli, P | 1 |
Pentecost, BT | 1 |
Body, JJ; Lacroix, M; Marie, PJ; Siwek, B | 1 |
Angeloni, SV; Lindsey, RK; Martin, MB; Saceda, M; Solomon, H | 1 |
Calvo, F; Castanas, E; Hatzoglou, A; Martin, PM; Panagiotou, S | 1 |
El Khissiin, A; Laios, I; Larsimont, D; Leclercq, G; Legros, N; Querton, G; Seo, HS | 1 |
Brinkmann, U; Keppler-Hafkemeyer, A; Pastan, I | 1 |
Davie, JR; Hager, GL; Holth, LT; Htun, H; Walker, D | 1 |
Ogretmen, B; Safa, AR | 1 |
Lu, R; Serrero, G | 1 |
Oberley, LW; Oberley, TD; Thongphasuk, J | 1 |
Alitalo, K; Härkönen, PL; Joukov, V; Karkkainen, MJ; Ruohola, JK; Valve, EM | 1 |
Pethe, V; Shekhar, PV | 1 |
Bedner, E; Cheng, W; Darzynkiewicz, Z; Deptala, A; Li, X; Traganos, F | 1 |
Heyns, W; Swinnen, JV; Ulrix, W; Verhoeven, G | 1 |
Dong, HY; Hashimoto, S; Inadera, H; Matsushima, K; Nagai, S; Suzuki, T; Toyoda, N; Yamashita, T | 1 |
Clarkin, CE; Weber, BL; Zhang, H | 1 |
El Khissiin, A; Journé, F; Laïos, I; Leclercq, G; Seo, HS | 1 |
Luo, X; Moreno, J; Shi, Y; Tondravi, M; Wang, R; Zhang, L; Zhang, X | 1 |
Basu, A; Mohanty, S; Sun, B | 1 |
Kumar, P; Mark, PJ; Minchin, RF; Ratajczak, T; Ward, BK | 1 |
Fillion, C; Fournier, A; Grenier, J; Labrie, C; Labrie, Y; Qi, H | 1 |
Atsumi, GI; Chilton, FH; Clay, CE; High, KP | 1 |
Chinnaiyan, AM; Kumar-Sinha, C; Sreekumar, A; Varambally, S | 1 |
Chen, HY; Davie, JR; Sun, JM | 1 |
Barnes, CJ; Kumar, R; Li, F; Mandal, M; Vadlamudi, RK | 1 |
Labrie, C; Pouliot, F | 1 |
Beery, R; Geier, A; Haimsohn, M; Kanety, H; Karasik, A | 1 |
Keshamouni, VG; Mattingly, RR; Reddy, KB | 1 |
Dorssers, LC; Foekens, JA; Klijn, JG; Martens, JW; Sieuwerts, AM | 1 |
Kako, T | 1 |
Lippman, ME; Monaco, ME | 1 |
Keyomarsi, K; Lee, SW; Paul, D; Sager, R; Tomasetto, C | 1 |
Hug, V; Levy, JR | 1 |
Eskild, W; Hansson, V; Knutsen, HK; Landmark, BF; Ree, AH | 1 |
Alkhalaf, M; Murphy, LC | 1 |
Bracke, M; De Potter, C; Mareel, M; Put, W; Van Damme, J; van Larebeke, N; Verhasselt, B | 1 |
Chiew, YE; deFazio, A; Donoghue, C; Lee, CS; Sutherland, RL | 1 |
Patel, KV; Schrey, MP; Tezapsidis, N | 1 |
Blench, I; Ghilchik, MW; Morris, HR; Patel, SR; Reed, MJ; Singh, A | 1 |
Chapman, O; Duncan, L; Purohit, A; Reed, MJ | 1 |
Furukawa, Y; Hayashi, K; Hirota, M | 1 |
Beery, R; Geier, A; Haimshon, M; Hemi, R; Lunenfeld, B | 1 |
Desprez, PY; Poujol, D; Saez, S | 1 |
de Fazio, A; Kelly, PA; Ormandy, CJ; Sutherland, RL | 1 |
Baulieu, EE; Mercier-Bodard, C; Nivet, V | 1 |
Feldman, D; Krishnan, AV | 1 |
Hakes, TB; Liu, J; Mukhopadhyay, B; Osborne, MP; Telang, NT; Tiwari, RK; Wong, GY | 1 |
Bellomo, G; Finardi, G; Mirabelli, F; Nicotera, P; Orrenius, S; Perotti, M; Taddei, F | 1 |
Albertini, A; Di Lorenzo, D; Zava, D | 1 |
Hamburger, AW; Pinnamaneni, GD | 1 |
Clarke, CL; Graham, J; Roman, SD; Sutherland, RL | 1 |
Henle, KJ; Monson, TP; Stone, A | 1 |
Abe, M; Kufe, D | 1 |
Penhallow, RC; Sussman, HH | 1 |
Chalbos, D; Joyeux, C; Rochefort, H | 1 |
Leake, RE; Macnab, JC; Offord, EA | 1 |
Asoh, K; Kohno, K; Kuwano, M; Mawatari, M; Mizoguchi, H; Ono, M; Watanabe, Y | 1 |
Kovach, JS; Vuk-Pavlović, S | 1 |
Lindsey, RK; Lippman, ME; Martin, MB; Puente, M; Saceda, M | 1 |
Cavailles, V; Garcia, M; Rochefort, H | 1 |
Hayashi, K; Kida, N; Mori, K; Yoshimura, T | 1 |
Degani, H; Neeman, M | 1 |
Kennedy, BJ; Kiang, DT; Kollander, RE; Thomas, T | 1 |
Eisman, JA; Frampton, RJ; Sher, E | 1 |
Lazarus, L; Murphy, LC; Murphy, LJ; Stead, B; Sutherland, RL | 1 |
Mulkins, MA; Sussman, HH | 1 |
Baglioni, C; Latham, K; Ruggiero, V | 1 |
Dubik, D; Shiu, RP | 1 |
Mira-y-Lopez, R; Ossowski, L | 1 |
Benz, C; Lee, WM; Liu, E; Santos, GF; Scott, GK | 1 |
Cormier, EM; Jordan, VC; Welshons, WV; Williams, PO; Wolf, MF | 1 |
Baiocchi, G; Iacobelli, S; Mancuso, S; Natoli, C; Panici, PB; Perrone, L; Scambia, G | 1 |
Fernandez-Pol, JA; Hamilton, PD; Klos, DJ; Talkad, VD | 1 |
Aitken, SC; Kasid, A; Lippman, ME; Schoenberg, DR | 1 |
Friedman, RM; Johnson, GS; Pastan, I | 1 |
170 other study(ies) available for cycloheximide and Breast Neoplasms
Article | Year |
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Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells.
Topics: Alkaloids; Breast Neoplasms; DNA-Binding Proteins; Emetine; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Structure; Nuclear Proteins; Quinazolines; Rubiaceae; Terpenes; Tetrahydroisoquinolines; Transcription Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2005 |
Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.
Topics: Aegle; Antineoplastic Agents, Phytogenic; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cell Survival; Coumarins; Dietary Supplements; Female; Humans; Hypoxia-Inducible Factor 1; Mitochondria; Plant Extracts | 2013 |
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.
Topics: Animals; Benzofurans; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Eukaryotic Initiation Factor-4A; Female; Half-Life; Humans; Ligands; Mice; Mice, Nude; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Rats; RNA, Messenger; Structure-Activity Relationship | 2020 |
Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Female; Humans; Proteasome Endopeptidase Complex; Tumor Suppressor Protein p53 | 2023 |
SETDB2 promoted breast cancer stem cell maintenance by interaction with and stabilization of ΔNp63α protein.
Topics: Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Female; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Histone-Lysine N-Methyltransferase; Humans; Leupeptins; Neoplastic Stem Cells; Transcription Factors; Tumor Suppressor Proteins | 2020 |
Circular RNA‑MTO1 suppresses breast cancer cell viability and reverses monastrol resistance through regulating the TRAF4/Eg5 axis.
Topics: Antimitotic Agents; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cycloheximide; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kinesins; Oligonucleotide Array Sequence Analysis; Pyrimidines; RNA; RNA-Binding Proteins; RNA, Circular; RNA, Messenger; Signal Transduction; Thiones; TNF Receptor-Associated Factor 4; Up-Regulation | 2018 |
Prolactin/Stat5 and androgen R1881 coactivate carboxypeptidase-D gene in breast cancer cells.
Topics: Androgens; Base Sequence; Breast Neoplasms; Consensus Sequence; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Induction; Female; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; MCF-7 Cells; Metribolone; Prolactin; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Proteins; Receptors, Androgen; STAT5 Transcription Factor | 2014 |
Phosphatidic Acid Increases Epidermal Growth Factor Receptor Expression by Stabilizing mRNA Decay and by Inhibiting Lysosomal and Proteasomal Degradation of the Internalized Receptor.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cycloheximide; Endocytosis; ErbB Receptors; Female; Humans; Janus Kinase 3; Lysosomes; MCF-7 Cells; Phosphatidic Acids; Phospholipase D; Proteasome Endopeptidase Complex; Proteolysis; Ribonucleases; RNA Interference; RNA Stability; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2015 |
OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Cysteine Endopeptidases; Deubiquitinating Enzymes; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Epirubicin; Female; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Protein Synthesis Inhibitors; RNA Interference; RNA, Small Interfering; Ubiquitination | 2016 |
The degradation of EZH2 mediated by lncRNA ANCR attenuated the invasion and metastasis of breast cancer.
Topics: Animals; Breast Neoplasms; Cadherins; CDC2 Protein Kinase; Cell Line, Tumor; Cell Movement; Cycloheximide; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Leupeptins; Lung Neoplasms; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Proteasome Endopeptidase Complex; Protein Binding; RNA, Long Noncoding; Ubiquitin | 2017 |
Argonaute-2 expression is regulated by epidermal growth factor receptor and mitogen-activated protein kinase signaling and correlates with a transformed phenotype in breast cancer cells.
Topics: Argonaute Proteins; Breast Neoplasms; Cell Aggregation; Cell Movement; Cell Transformation, Neoplastic; Cycloheximide; Disease Progression; ErbB Receptors; Eukaryotic Initiation Factor-2; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Phenotype; Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Wound Healing | 2009 |
Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells.
Topics: 3' Untranslated Regions; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; MicroRNAs; Nucleic Acid Synthesis Inhibitors; Promoter Regions, Genetic; Protein Synthesis Inhibitors; ras GTPase-Activating Proteins; RNA-Binding Proteins; RNA, Antisense; Tamoxifen | 2009 |
Progesterone stimulates mitochondrial activity with subsequent inhibition of apoptosis in MCF-10A benign breast epithelial cells.
Topics: Adenosine Triphosphate; Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Cycloheximide; Epithelial Cells; fas Receptor; Female; Flow Cytometry; Humans; Inhibitor of Differentiation Protein 1; Kallikreins; Male; Matrix Metalloproteinases; Membrane Potential, Mitochondrial; Mitochondria; Oxygen Consumption; Progesterone; Protein Synthesis Inhibitors; Real-Time Polymerase Chain Reaction; Receptors, Progesterone; Transforming Growth Factor beta1 | 2009 |
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells.
Topics: Breast Neoplasms; Cell Death; Cell Line, Tumor; Curcumin; Cycloheximide; Endoplasmic Reticulum; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Intracellular Signaling Peptides and Proteins; Mammary Glands, Human; MAP Kinase Kinase 4; Membrane Fusion; Mitochondrial Swelling; Proteasome Endopeptidase Complex; Superoxides; Vacuoles | 2010 |
Centchroman mediated apoptosis involves cross-talk between extrinsic/intrinsic pathways and oxidative regulation.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Centchroman; Cycloheximide; Dactinomycin; Down-Regulation; Estrogen Antagonists; Female; Humans; Immunoprecipitation; Oxidative Stress; Tamoxifen; Up-Regulation | 2010 |
Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Oligonucleotides; Promoter Regions, Genetic; RNA Interference; Signal Transduction; Up-Regulation | 2011 |
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Cycloheximide; Docetaxel; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; MCF-7 Cells; NF-kappa B; Ovarian Neoplasms; Paclitaxel; Protein Synthesis Inhibitors; Proteolysis; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Taxoids; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2012 |
Transcriptional activation of breast cancer-associated gene 2 by estrogen receptor.
Topics: Breast Neoplasms; Chromatin Immunoprecipitation; Cycloheximide; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Humans; Luciferases, Renilla; MCF-7 Cells; Protein Binding; Protein Synthesis Inhibitors; Response Elements; RNA Interference; Transcriptional Activation; Ubiquitin-Protein Ligases | 2012 |
Newcastle disease virus Malaysian strain AF2240 induces apoptosis in MCF-7 human breast carcinoma cells at an early stage of the virus life cycle.
Topics: Animals; Apoptosis; Breast Neoplasms; Caspase 8; Cell Line, Tumor; Chlorocebus aethiops; Cycloheximide; Enzyme Activation; Female; Humans; Life Cycle Stages; MCF-7 Cells; Mitochondria; Newcastle disease virus; Nucleocapsid Proteins; Nucleoproteins; Ultraviolet Rays; Vero Cells; Viral Proteins; Virus Attachment; Virus Replication | 2013 |
Retinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines.
Topics: Breast; Breast Neoplasms; Carcinoma; Cell Division; Cycloheximide; Dactinomycin; Drug Synergism; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Kinetics; Male; Prostate; Protein Synthesis Inhibitors; Receptors, Estrogen; Receptors, Retinoic Acid; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 2002 |
Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis.
Topics: Apoptosis; Breast Neoplasms; Cycloheximide; Female; Genes, Reporter; Green Fluorescent Proteins; Humans; Intracellular Membranes; Luminescent Proteins; Permeability; Phenanthridines; Recombinant Proteins; Submitochondrial Particles; Superoxides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vitamin K 3 | 2003 |
Estradiol-induced vascular endothelial growth factor-A expression in breast tumor cells is biphasic and regulated by estrogen receptor-alpha dependent pathway.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Protein Synthesis Inhibitors; Receptors, Estrogen; RNA, Messenger; RNA, Neoplasm; Transfection; Vascular Endothelial Growth Factor A | 2003 |
Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells.
Topics: Breast Neoplasms; Carcinoma; Cell Division; Chemokine CXCL12; Chemokines, CXC; Cycloheximide; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Mitogens; Ovarian Neoplasms; Protein Isoforms; Protein Synthesis Inhibitors; Receptors, CXCR4; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured | 2003 |
The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes.
Topics: Animals; Breast Neoplasms; Cycloheximide; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Female; Flavonoids; Humans; Macromolecular Substances; MAP Kinase Signaling System; Mice; Models, Biological; Neoplasm Proteins; Peptide Hydrolases; Polychlorinated Dibenzodioxins; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Receptor Cross-Talk; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Recombinant Fusion Proteins; Sequence Deletion; Transcriptional Activation; Transfection; Ubiquitin | 2003 |
BMP2 exposure results in decreased PTEN protein degradation and increased PTEN levels.
Topics: Blotting, Western; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Breast Neoplasms; Cell Division; Cell Movement; Cycloheximide; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Humans; Ligases; Mutation; Phosphoric Monoester Hydrolases; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; PTEN Phosphohydrolase; Receptors, Growth Factor; Syndrome; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Conjugating Enzymes | 2003 |
Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells.
Topics: Acetylcysteine; Animals; Blotting, Western; Breast Neoplasms; Brefeldin A; Cell Communication; Cell Membrane; Connexin 43; Cycloheximide; Cysteine Endopeptidases; Gap Junctions; Humans; Immunohistochemistry; Lysosomes; Mammary Neoplasms, Animal; Microscopy, Confocal; Microscopy, Electron; Microscopy, Fluorescence; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Protein Transport; Rats; Signal Transduction; Time Factors; Tumor Cells, Cultured | 2003 |
Effects of the phytoestrogens genistein and daidzein on BRCA2 tumor suppressor gene expression in breast cell lines.
Topics: Antibiotics, Antineoplastic; BRCA2 Protein; Breast Neoplasms; Cell Division; Cell Line; Chromatography, Affinity; Cycloheximide; Dactinomycin; Gene Expression Regulation, Neoplastic; Genes, BRCA2; Genistein; Humans; Isoflavones; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2003 |
Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1.
Topics: Breast Neoplasms; Cycloheximide; DNA-Binding Proteins; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Galactosyltransferases; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Protein 4; Neoplasm Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Pesticides; Phytoestrogens; Protein Synthesis Inhibitors; Puromycin; Receptors, Estrogen; Regulatory Factor X Transcription Factors; Tamoxifen; Transcription Factors; Tumor Cells, Cultured; X-Box Binding Protein 1 | 2004 |
Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation.
Topics: Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Cycloheximide; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen; Time Factors; Tumor Cells, Cultured | 2004 |
Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappaB through c-FLIP-L expression.
Topics: Adenocarcinoma; Anti-Infective Agents; Apoptosis; Binding Sites; Breast Neoplasms; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cycloheximide; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; NF-kappa B; Nitriles; Receptor, ErbB-2; Stimulation, Chemical; Sulfones; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2004 |
Transcription factor EGR3 is involved in the estrogen-signaling pathway in breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Early Growth Response Protein 3; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Fas Ligand Protein; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Membrane Glycoproteins; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Repressor Proteins; Signal Transduction; Transcription Factors | 2004 |
The Ah receptor inhibits estrogen-induced estrogen receptor beta in breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Estrogen Receptor beta; Estrogens; Humans; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Signal Transduction | 2004 |
Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Breast; Breast Neoplasms; Concanavalin A; Cycloheximide; Dactinomycin; Enzyme Activation; Enzyme Activators; Female; Fibroadenoma; Gelatin; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Organ Culture Techniques; Protease Inhibitors; Protein Biosynthesis; Protein Kinase C; Protein Synthesis Inhibitors; Transcription, Genetic | 2004 |
Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells: evidence for distinct degradative pathways.
Topics: Breast Neoplasms; Cycloheximide; Enzyme Inhibitors; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Immunoenzyme Techniques; Lactones; Leupeptins; Ligands; Macrolides; Molecular Chaperones; Proteasome Inhibitors; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyrrolidines; Signal Transduction; Tamoxifen; Thiophenes; Tumor Cells, Cultured | 2004 |
Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.
Topics: Benzoquinones; Breast Neoplasms; Cell Fractionation; Cell Nucleus; Cell Proliferation; Cycloheximide; Cytoplasm; Extracellular Signal-Regulated MAP Kinases; Female; Genes, Tumor Suppressor; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Protein Binding; Protein Denaturation; Protein Kinase Inhibitors; Protein Kinases; Rifabutin; Signal Transduction; Tumor Cells, Cultured | 2005 |
In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
Topics: Breast Neoplasms; Cell Line, Tumor; Chromones; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Female; Fibroblast Growth Factor 2; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; MAP Kinase Kinase 1; Morpholines; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factors; Vascular Endothelial Growth Factor A | 2005 |
Release kinetics from bio-polymeric nanoparticles encapsulating protein synthesis inhibitor- cycloheximide, for possible therapeutic applications.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coated Materials, Biocompatible; Cycloheximide; Delayed-Action Preparations; Diffusion; Drug Carriers; Gelatin; Humans; Hydrogen-Ion Concentration; Kinetics; Materials Testing; Nanotubes; Particle Size; Protein Synthesis Inhibitors | 2005 |
Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Down-Regulation; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Genes, Reporter; Humans; Leupeptins; Ligands; Luciferases; Methionine; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Sulfur Radioisotopes; Tamoxifen; Transcription, Genetic; Tritium | 2005 |
Membrane 5alpha-pregnane-3,20-dione (5alphaP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5alphaP and down-regulated by the progesterone metabolites, 3alpha-dihydroprogesterone and 20alpha-dihydroprogesterone, with
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Fractionation; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Female; Humans; Progesterone; Receptors, Estradiol; Receptors, Progesterone; Up-Regulation | 2005 |
Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line.
Topics: Binding, Competitive; Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cycloheximide; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Iodine Radioisotopes; Neuropeptide Y; Receptors, Neuropeptide Y; RNA, Messenger; Up-Regulation | 2006 |
Estrogen regulation of the glucuronidation enzyme UGT2B15 in estrogen receptor-positive breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Estradiol; Estrogen Antagonists; Fulvestrant; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Humans; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Up-Regulation | 2006 |
Unique resistance of breast carcinoma cell line T47D to TRAIL but not anti-Fas is linked to p43cFLIP(L).
Topics: Antibodies, Monoclonal; Breast Neoplasms; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Cycloheximide; Drug Resistance, Neoplasm; fas Receptor; Fas-Associated Death Domain Protein; Female; Humans; Immunoprecipitation; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells.
Topics: Antimutagenic Agents; Blotting, Northern; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cobalt; Cycloheximide; Cytochrome P-450 CYP1A1; Cytosol; Drug Antagonism; Environmental Pollutants; Enzyme Induction; Female; Gene Expression; Humans; Polychlorinated Dibenzodioxins; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; RNA, Messenger; Ubiquitin-Protein Ligases | 2007 |
CD44 crosslinking-mediated matrix metalloproteinase-9 relocation in breast tumor cells leads to enhanced metastasis.
Topics: Animals; Breast Neoplasms; Cycloheximide; Female; Humans; Hyaluronan Receptors; Immunoprecipitation; Matrix Metalloproteinase 9; Mice; Myoblasts; Neoplasm Invasiveness; Neoplasm Metastasis | 2007 |
Cell growth inhibition by okadaic acid involves gut-enriched Kruppel-like factor mediated enhanced expression of c-Myc.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Okadaic Acid; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Signal Transduction; Transcription, Genetic | 2007 |
Emetine regulates the alternative splicing of Bcl-x through a protein phosphatase 1-dependent mechanism.
Topics: Alternative Splicing; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cycloheximide; Down-Regulation; Emetine; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Marine Toxins; Okadaic Acid; Oxazoles; Prostatic Neoplasms; Protein Phosphatase 1; Protein Phosphatase 2; Up-Regulation; Uterine Cervical Neoplasms | 2007 |
Estradiol preferentially enhances extracellular tissue plasminogen activators of MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Cycloheximide; Dactinomycin; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Estradiol; Female; Humans; Kinetics; Molecular Weight; Plasminogen Activators; Progesterone; Testosterone | 1984 |
Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7.
Topics: Breast Neoplasms; Cells, Cultured; Cycloheximide; DNA, Neoplasm; Estradiol; Female; Gene Expression Regulation; Humans; Time Factors; Transcription, Genetic | 1984 |
Progesterone receptor replenishment in T47D human breast cancer cells. Roles of protein synthesis and hormone metabolism.
Topics: Breast Neoplasms; Cell Line; Cycloheximide; Female; Humans; Kinetics; Progesterone; Promegestone; Protein Biosynthesis; Receptors, Progesterone | 1983 |
Effect of metformin on insulin binding to receptors in cultured human lymphocytes and cancer cells.
Topics: Breast Neoplasms; Cells, Cultured; Cycloheximide; Humans; Insulin; Lymphocytes; Metformin; Phenformin; Receptor, Insulin | 1982 |
Regulation of protein accumulation in cultured cells.
Topics: Animals; Blood; Breast Neoplasms; Cell Line; Cycloheximide; Cytological Techniques; Hormones; Humans; Leucine; Milk; Muscles; Protein Biosynthesis; Proteins; Rats; Tyrosine | 1982 |
Nuclear estrogen receptors. Effect of inhibitors on processing and steady state levels.
Topics: Binding, Competitive; Breast Neoplasms; Cell Line; Cell Nucleus; Cycloheximide; Cytosol; Dactinomycin; Deoxyadenosines; Estradiol; Female; Humans; Kinetics; Receptors, Estrogen | 1980 |
Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.
Topics: Breast Neoplasms; Bromodeoxyuridine; Butyrates; Cell Nucleus; Cells, Cultured; Cycloheximide; Cytoplasm; Estradiol; Female; Humans; Nafoxidine; Promegestone; Receptors, Estrogen; Receptors, Progesterone | 1982 |
Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells.
Topics: Breast Neoplasms; Concanavalin A; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Activation; Gelatinases; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Protein Precursors; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Estrogen and phorbol esters regulate amphiregulin expression by two separate mechanisms in human breast cancer cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amphiregulin; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Bryostatins; Culture Media, Conditioned; Cycloheximide; Dose-Response Relationship, Drug; EGF Family of Proteins; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation, Neoplastic; Glycoproteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Isoquinolines; Lactones; Macrolides; Piperazines; Polyunsaturated Alkamides; Protein Kinase C; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Regulation of insulin-like growth factor-binding-protein-1, 2, 3, 4, 5, and 6: synthesis, secretion, and gene expression in estrogen receptor-negative human breast carcinoma cells.
Topics: Blotting, Western; Breast Neoplasms; Carrier Proteins; Cycloheximide; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunosorbent Techniques; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 6; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Receptors, Estrogen; RNA, Messenger; RNA, Neoplasm; Transfection; Tretinoin; Tumor Cells, Cultured | 1993 |
Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Cycloheximide; Feedback; Gene Expression Regulation; Humans; Kinetics; Melatonin; Receptors, Estrogen; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
Involvement of phospholipase C in heat-shock-induced phosphorylation of P-glycoprotein in multidrug resistant human breast cancer cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cycloheximide; Diglycerides; Drug Resistance, Multiple; Estrenes; Hot Temperature; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Phosphorylation; Protein Kinase C; Pyrrolidinones; Staurosporine; Tumor Cells, Cultured; Type C Phospholipases | 1995 |
Effects of retinoic acid and gamma-interferon on expression of retinoic acid receptor and cellular retinoic acid-binding protein in breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cycloheximide; Drug Synergism; Humans; Interferon-gamma; Receptors, Retinoic Acid; RNA, Messenger; Tretinoin; Tumor Cells, Cultured | 1995 |
Multiple pathways are involved in protection of MCF-7 cells against death due to protein synthesis inhibition.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aurintricarboxylic Acid; Breast Neoplasms; Cell Survival; Cycloheximide; DNA Damage; Genistein; Humans; Insulin-Like Growth Factor I; Isoflavones; Microscopy, Electron; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Hormonal and feedback regulation of putrescine and spermidine transport in human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Cell Division; Cell Line; Cycloheximide; Drug Synergism; Eflornithine; Estradiol; Feedback; Humans; Insulin; Kinetics; Putrescine; Spermidine; Spermine; Tretinoin; Tumor Cells, Cultured | 1995 |
Existence of a commitment program for mitosis in early G1 in tumour cells.
Topics: 3T3 Cells; Animals; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cycloheximide; DNA, Neoplasm; Fibroblasts; G1 Phase; Glioma; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Inbred BALB C; Mitosis; Neoplasms; Time Factors; Tumor Cells, Cultured | 1995 |
1,25-Dihydroxyvitamin D3 enhances the expression of transforming growth factor beta 1 and its latent form binding protein in cultured breast carcinoma cells.
Topics: Breast Neoplasms; Calcitriol; Carrier Proteins; Cycloheximide; Dactinomycin; Humans; Intracellular Signaling Peptides and Proteins; Latent TGF-beta Binding Proteins; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured | 1995 |
Epidermal growth factor, phorbol esters, and aurintricarboxylic acid are survival factors for MDA-231 cells exposed to adriamycin.
Topics: Adenosine Triphosphate; Apoptosis; Aurintricarboxylic Acid; Breast Neoplasms; Cell Survival; Cycloheximide; DNA, Neoplasm; Doxorubicin; Epidermal Growth Factor; Humans; Insulin-Like Growth Factor I; L-Lactate Dehydrogenase; Microscopy, Electron; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
1,25-Dihydroxyvitamin D3 potentiates the cytotoxic effect of TNF on human breast cancer cells.
Topics: Animals; Antineoplastic Agents; Aorta; Breast Neoplasms; Calcitriol; Cattle; Cell Death; Cycloheximide; Drug Synergism; Endothelium, Vascular; Humans; Proteins; Tumor Necrosis Factor-alpha | 1994 |
Cycloheximide inhibits the cytotoxicity of paclitaxel (Taxol).
Topics: Adenocarcinoma; Breast Neoplasms; Cell Cycle; Cell Death; Cycloheximide; DNA, Neoplasm; Drug Interactions; Flow Cytometry; Humans; Lung Neoplasms; Mitotic Index; Neoplasm Proteins; Paclitaxel; Tumor Cells, Cultured | 1994 |
Apolipoprotein D gene induction by retinoic acid is concomitant with growth arrest and cell differentiation in human breast cancer cells.
Topics: Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Cell Differentiation; Cell Division; Cell Nucleus; Cell-Free System; Cycloheximide; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Isomerism; Lactoferrin; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Tretinoin; Tumor Cells, Cultured | 1994 |
Effect of basic fibroblast growth factor on synthesis/secretion of pS2 protein by human breast cancer cells (MCF-7).
Topics: Breast Neoplasms; Cycloheximide; Dactinomycin; Drug Synergism; Estradiol; Female; Fibroblast Growth Factor 2; Humans; Kinetics; Neoplasm Proteins; Proteins; RNA, Messenger; Steroids; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1994 |
Regulation of estradiol 17 beta-hydroxysteroid dehydrogenase expression and activity by retinoic acid in T47D breast cancer cells.
Topics: Breast Neoplasms; Cycloheximide; Cytokines; Estradiol Dehydrogenases; Female; Growth Substances; Hormones; Humans; Pregnancy; Proteins; RNA, Messenger; Tretinoin; Tumor Cells, Cultured | 1994 |
Expression of the c-erbB2 gene in the BT474 human mammary tumor cell line: measurement of c-erbB2 mRNA half-life.
Topics: Adenocarcinoma; Breast Neoplasms; Cycloheximide; Dactinomycin; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1993 |
Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.
Topics: Amino Acid Sequence; Aphidicolin; Breast Neoplasms; CDC2 Protein Kinase; Cyclins; Cycloheximide; Down-Regulation; Emetine; Enzyme Activation; Flavonoids; Humans; Maturation-Promoting Factor; Mitosis; Molecular Sequence Data; Phosphorylation; Piperidines; Precipitin Tests; S Phase; Tumor Cells, Cultured | 1993 |
Mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated decrease of the nuclear estrogen receptor in MCF-7 human breast cancer cells.
Topics: Analysis of Variance; Animals; Base Sequence; Benzoflavones; Blotting, Northern; Breast Neoplasms; Cell Nucleus; Cycloheximide; DNA; Humans; Molecular Sequence Data; Polychlorinated Dibenzodioxins; Protein Binding; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Signal Transduction; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Differential regulation of matrix Gla protein (MGP) gene expression by retinoic acid and estrogen in human breast carcinoma cells.
Topics: Amino Acid Sequence; Breast Neoplasms; Calcium-Binding Proteins; Carcinoma; Cycloheximide; Estradiol; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I; Matrix Gla Protein; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Tretinoin | 1993 |
Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate in human breast cancer cells.
Topics: Breast Neoplasms; Carcinogens; Cycloheximide; Diglycerides; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Protein Kinase C; Receptors, Prolactin; RNA, Messenger; RNA, Neoplasm; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Regulation of estrogen receptor expression in breast cancer.
Topics: Breast Neoplasms; Cycloheximide; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Hormone-Dependent; Receptors, Estrogen; RNA, Messenger; RNA, Neoplasm; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Effects of cycloheximide on the induction of CYP1A1 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in three human breast cancer cell lines.
Topics: Base Sequence; Breast Neoplasms; Cycloheximide; Cytochrome P-450 Enzyme System; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Induction of jun gene family members by transforming growth factor alpha but not 17 beta-estradiol in human breast cancer cells.
Topics: Breast Neoplasms; Cycloheximide; DNA, Neoplasm; Estradiol; Gene Expression; Genes, fos; Genes, jun; Humans; In Vitro Techniques; RNA, Neoplasm; Time Factors; Transcription, Genetic; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Interleukin 6 stimulates the production of immunoreactive endothelin 1 in human breast cancer cells.
Topics: Breast Neoplasms; Cycloheximide; Cytokines; Dactinomycin; Endothelins; Estrogens; Humans; Interleukin-6; Stimulation, Chemical; Tamoxifen; Tumor Cells, Cultured | 1993 |
Epidermal growth factor and insulin-like growth factor-1 preserve cell viability in the absence of protein synthesis.
Topics: Breast Neoplasms; Cell Survival; Colonic Neoplasms; Cycloheximide; Epidermal Growth Factor; Humans; Insulin-Like Growth Factor I; Leucine; Mouth Neoplasms; Protein Biosynthesis; Tumor Cells, Cultured | 1993 |
Estrogenic and antiestrogenic regulation of the half-life of covalently labeled estrogen receptor in MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Cell Nucleus; Cycloheximide; Cytosol; Estradiol; Estrogen Antagonists; Estrogens; Half-Life; Humans; Indicators and Reagents; Molecular Weight; Protein Synthesis Inhibitors; Puromycin; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Tumor Cells, Cultured; Up-Regulation | 1996 |
Bimodal regulation of epidermal growth factor receptor by estrogen in breast cancer cells.
Topics: Base Sequence; Breast Neoplasms; Cell Line; Cell Nucleus; Consensus Sequence; Cycloheximide; Dactinomycin; Down-Regulation; ErbB Receptors; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Models, Biological; Molecular Sequence Data; Polyunsaturated Alkamides; Promoter Regions, Genetic; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1996 |
Nuclear factor kappa B (NF-kappa B), nuclear factor interleukin-6 (NFIL-6 or C/EBP beta) and nuclear factor interleukin-6 beta (NFIL6-beta or C/EBP delta) are not sufficient to activate the endogenous interleukin-6 gene in the human breast carcinoma cell
Topics: Base Sequence; Breast Neoplasms; Carcinoma; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Cycloheximide; Cytokines; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Molecular Sequence Data; NF-kappa B; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1996 |
Induction of apoptosis in MDA-231 cells by protein synthesis inhibitors is suppressed by multiple agents.
Topics: Alkaloids; Apoptosis; Breast Neoplasms; Cycloheximide; DNA; Epidermal Growth Factor; Female; Humans; Protein Biosynthesis; Protein Synthesis Inhibitors; Ricin; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
BRCA1 and BRCA2 mRNA levels are coordinately elevated in human breast cancer cells in response to estrogen.
Topics: BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Cycloheximide; Estrogen Antagonists; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured | 1996 |
2,2'-Dithiobis(N-ethyl-spermine-5-carboxamide) is a high affinity, membrane-impermeant antagonist of the mammalian polyamine transport system.
Topics: Animals; Breast Neoplasms; Cell Division; Cell Membrane; CHO Cells; Cricetinae; Cycloheximide; Cysteamine; Disulfides; Female; Humans; Indicators and Reagents; Kinetics; Molecular Structure; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship; Sulfhydryl Compounds; Tumor Cells, Cultured | 1996 |
Induction of metalloproteinase (MMP1) expression by epidermal growth factor (EGF) receptor stimulation and serum deprivation in human breast tumour cells.
Topics: Blotting, Northern; Breast Neoplasms; Collagenases; Culture Media, Serum-Free; Cycloheximide; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Matrix Metalloproteinase 1; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1996 |
Interaction between estradiol and cAMP in the regulation of specific gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Carcinoma; Cholera Toxin; Cyclic AMP; Cycloheximide; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phosphodiesterase Inhibitors; Polyunsaturated Alkamides; Protein Synthesis Inhibitors; Proteins; Receptors, Estradiol; RNA, Messenger; RNA, Neoplasm; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1996 |
Retinoic acids differentially regulate NOR-1 and its closely related orphan nuclear receptor genes in breast cancer cell line MCF-7.
Topics: Alitretinoin; Breast Neoplasms; Colforsin; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1997 |
Phosphorylation of A 27-kDa protein correlates with survival of protein-synthesis-inhibited MCF-7 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aurintricarboxylic Acid; Breast Neoplasms; Carcinoma; Cell Survival; Cycloheximide; Cytosol; Epidermal Growth Factor; Heat-Shock Proteins; Humans; Insulin-Like Growth Factor I; Isoelectric Point; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1997 |
Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells.
Topics: 16,16-Dimethylprostaglandin E2; Anti-Ulcer Agents; Breast Neoplasms; Cell Count; Cell Division; Cycloheximide; Cyclooxygenase 2; DNA Replication; DNA, Neoplasm; Enzyme Induction; Female; Flurbiprofen; Humans; Isoenzymes; Male; Membrane Proteins; Ovarian Neoplasms; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1997 |
Growth inhibition of human breast cancer cells by 1,25-dihydroxyvitamin D3 is accompanied by induction of apolipoprotein D expression.
Topics: Antineoplastic Agents; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Calcitriol; Carcinoma; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Time Factors; Tumor Cells, Cultured | 1997 |
Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis.
Topics: Adenosine Triphosphate; Apoptosis; Breast Neoplasms; Cycloheximide; Deoxyglucose; Down-Regulation; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Time Factors; Tritium; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Protein synthesis is not implicated in the ligand-dependent activation of the estrogen receptor in MCF-7 cells.
Topics: Binding, Competitive; Breast Neoplasms; Cycloheximide; Estradiol; Gene Expression Regulation; Humans; Protein Synthesis Inhibitors; Puromycin; Receptors, Estrogen; Receptors, Progesterone; Tumor Cells, Cultured | 1997 |
Expression of prostate-specific antigen and prostate-specific membrane antigen transcripts in blood cells: implications for the detection of hematogenous prostate cells and standardization.
Topics: Adult; Aged; Animals; Antigens, Surface; Blood Cells; Breast Neoplasms; Carboxypeptidases; Cell Line; Cell Line, Transformed; CHO Cells; Cricetinae; Cycloheximide; DNA Primers; Exons; Female; Glutamate Carboxypeptidase II; Heterozygote; Humans; Jurkat Cells; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Recombinant Proteins; Sensitivity and Specificity; Stochastic Processes; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
EGF-induced programmed cell death of human mammary carcinoma MDA-MB-468 cells is preceded by activation AP-1.
Topics: Apoptosis; Breast Neoplasms; Chromatin; Cycloheximide; DNA Fragmentation; DNA-Binding Proteins; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Homeodomain Proteins; Host Cell Factor C1; Humans; Octamer Transcription Factor-1; Protein Biosynthesis; RNA, Messenger; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Expression and estrogen regulation of the HEM45 MRNA in human tumor lines and in the rat uterus.
Topics: Animals; Base Sequence; Breast Neoplasms; Cycloheximide; DNA, Complementary; Estradiol; Female; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Estrogen; RNA, Messenger; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured; Uterus | 1998 |
Production and regulation of interleukin-11 by breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cycloheximide; Gene Expression Regulation; Growth Substances; Interleukin-11; Interleukin-6; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured | 1998 |
Estradiol regulates estrogen receptor mRNA stability.
Topics: Breast Neoplasms; Centrifugation, Density Gradient; Cycloheximide; Drug Stability; Enzyme Inhibitors; Estradiol; Half-Life; Humans; Kinetics; Magnesium; Pactamycin; Placental Hormones; Protein Synthesis Inhibitors; Puromycin; Receptors, Estrogen; Ribonucleases; Ribosomes; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Modulation of the estrogen-regulated proteins cathepsin D and pS2 by opioid agonists in hormone-sensitive breast cancer cell lines (MCF7 and T47D): evidence for an interaction between the two systems.
Topics: Breast Neoplasms; Cathepsin D; Cell Division; Cycloheximide; Cytosol; Diprenorphine; Dose-Response Relationship, Drug; Estradiol; Ethylketocyclazocine; Etorphine; Female; Humans; Inhibitory Concentration 50; Narcotic Antagonists; Narcotics; Neoplasms, Hormone-Dependent; Protein Synthesis Inhibitors; Proteins; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1998 |
Estrogenic and anti-estrogenic regulation of estrogen receptor in MCF-7 breast-cancer cells: comparison of immunocytochemical data with biochemical measurements.
Topics: Breast Neoplasms; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Humans; Immunoenzyme Techniques; Immunohistochemistry; Kinetics; Okadaic Acid; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured | 1998 |
Role of caspases in immunotoxin-induced apoptosis of cancer cells.
Topics: ADP Ribose Transferases; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Apoptosis; Bacterial Toxins; Breast Neoplasms; Caspase 1; Caspase 2; Caspase 3; Caspases; Cycloheximide; Enzyme Activation; Exotoxins; Female; Humans; Immunotoxins; Oligopeptides; Peptide Fragments; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors | 1998 |
Direct visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor.
Topics: Breast Neoplasms; Cell Compartmentation; Cell Nucleolus; Cell Nucleus; Cycloheximide; DNA Primers; Estrogen Receptor alpha; Female; Gene Expression; Green Fluorescent Proteins; Humans; Ligands; Luminescent Proteins; Microscopy, Confocal; Protein Synthesis Inhibitors; Receptors, Estrogen; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured | 1999 |
Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region.
Topics: Base Sequence; Breast Neoplasms; Cycloheximide; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Molecular Sequence Data; NF-kappa B; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transcription Factor RelA; Tumor Cells, Cultured | 1999 |
Stimulation of PC cell-derived growth factor (epithelin/granulin precursor) expression by estradiol in human breast cancer cells.
Topics: Blotting, Western; Breast; Breast Neoplasms; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Epithelial Cells; Estradiol; Estrogen Antagonists; Gene Expression Regulation; Glycoproteins; Granulins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Progranulins; Protein Precursors; RNA, Messenger; Tamoxifen; Time Factors; Tumor Cells, Cultured | 1999 |
Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells.
Topics: Acetylcysteine; Breast Neoplasms; Cell Survival; Chlorides; Citrate (si)-Synthase; Cyclic N-Oxides; Cycloheximide; Enzyme Induction; Female; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Manganese Compounds; Manganese Poisoning; RNA, Messenger; Superoxide Dismutase; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
Vascular endothelial growth factors are differentially regulated by steroid hormones and antiestrogens in breast cancer cells.
Topics: Animals; Breast Neoplasms; Cycloheximide; Cyproterone Acetate; Endothelial Growth Factors; Estradiol; Estrogen Antagonists; Female; Humans; Lymphokines; Mammary Neoplasms, Experimental; Mice; Neoplasms, Hormone-Dependent; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Neoplasm; Steroids; Tamoxifen; Testosterone; Toremifene; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Estrogen inducibility of c-Ha-ras transcription in breast cancer cells. Identification of functional estrogen-responsive transcriptional regulatory elements in exon 1/intron 1 of the c-Ha-ras gene.
Topics: Animals; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Cycloheximide; Dactinomycin; Dexamethasone; Estradiol; Exons; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Introns; Mice; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1999 |
Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin.
Topics: Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Camptothecin; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA Replication; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Kinetics; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Androgens down-regulate the expression of the human homologue of paternally expressed gene-3 in the prostatic adenocarcinoma cell line LNCaP.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Kruppel-Like Transcription Factors; Male; Metribolone; Mice; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinases; Proteins; Receptors, Androgen; RNA, Messenger; Testosterone Congeners; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Zinc Fingers | 1999 |
WISP-2 as a novel estrogen-responsive gene in human breast cancer cells.
Topics: Air Pollutants, Occupational; Benzhydryl Compounds; Breast Neoplasms; CCN Intercellular Signaling Proteins; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Keratins; Neoplasm Proteins; Phenols; Repressor Proteins; RNA, Messenger; Time Factors; Transcription Factors; Tumor Cells, Cultured | 2000 |
Kinetics of BRCA1 regulation in response to UVC radiation.
Topics: Blotting, Western; BRCA1 Protein; Breast Neoplasms; Cycloheximide; DNA Damage; Dose-Response Relationship, Radiation; Epitopes; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Half-Life; Humans; Kinetics; Protein Synthesis Inhibitors; RNA, Messenger; S Phase; Tumor Cells, Cultured; Ultraviolet Rays | 2000 |
Evidence of an estrogen receptor form devoid of estrogen binding ability in MCF-7 cells.
Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Breast Neoplasms; Cell Nucleus; Cycloheximide; Cytosol; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Humans; Ligands; Protein Binding; Protein Synthesis Inhibitors; Receptors, Estrogen; Tamoxifen; Time Factors; Tritium; Tumor Cells, Cultured; Up-Regulation | 2000 |
Differential regulation of the expression of CD95 ligand, receptor activator of nuclear factor-kappa B ligand (RANKL), TNF-related apoptosis-inducing ligand (TRAIL), and TNF-alpha during T cell activation.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Calcium Signaling; Carrier Proteins; Cricetinae; Cycloheximide; Cytotoxicity, Immunologic; Dexamethasone; Enzyme Activation; Fas Ligand Protein; fas Receptor; Gene Expression Regulation; Hybridomas; Kinetics; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Mice; Multigene Family; Protein Kinase C; Protein Synthesis Inhibitors; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Antigen, T-Cell; Receptors, Tumor Necrosis Factor; T-Lymphocytes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Differential sensitivity of breast cancer cells to tumor necrosis factor-alpha: involvement of protein kinase C.
Topics: Antimetabolites; Apoptosis; Breast Neoplasms; Caspases; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Maleimides; NF-kappa B; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Carrier Proteins; Cycloheximide; Cyclophilins; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression; Humans; Peptidyl-Prolyl Isomerase F; Peptidylprolyl Isomerase; Protein Synthesis Inhibitors; RNA Stability; RNA, Messenger; Tacrolimus Binding Proteins; Tumor Cells, Cultured | 2001 |
Androgens induce expression of SPAK, a STE20/SPS1-related kinase, in LNCaP human prostate cancer cells.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Breast Neoplasms; Cloning, Molecular; Cycloheximide; DNA, Complementary; Female; Gene Expression Profiling; Humans; Male; Metribolone; Molecular Sequence Data; Prostatic Neoplasms; Protein Serine-Threonine Kinases; RNA, Messenger; Testosterone Congeners; Time Factors; Tumor Cells, Cultured; Up-Regulation | 2001 |
Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells.
Topics: Apoptosis; Blotting, Northern; Blotting, Western; Breast Neoplasms; Caspases; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dactinomycin; DNA, Complementary; Down-Regulation; Enzyme Activation; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Immunologic Factors; Ligands; Microscopy, Fluorescence; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Prostaglandin D2; Protein Synthesis Inhibitors; Receptors, Cytoplasmic and Nuclear; S Phase; Time Factors; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Molecular cross-talk between the TRAIL and interferon signaling pathways.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspases; Cycloheximide; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Interferons; Membrane Glycoproteins; Multigene Family; Oligonucleotide Array Sequence Analysis; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Effect of estradiol on histone acetylation dynamics in human breast cancer cells.
Topics: Acetylation; Acetyltransferases; Breast Neoplasms; Cell Fractionation; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Estradiol; Female; Histone Acetyltransferases; Histone Deacetylase 1; Histone Deacetylases; Histones; Humans; Models, Biological; Protein Isoforms; Protein Synthesis Inhibitors; Receptors, Estrogen; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured | 2001 |
Growth factor regulation of the molecular chaperone calnexin.
Topics: Breast Neoplasms; Calcium-Binding Proteins; Calnexin; Cell Membrane; Cycloheximide; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Confocal; Molecular Chaperones; Neuregulin-1; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Protein Transport; Receptor, ErbB-2; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured | 2001 |
Role of Smad1 and Smad4 proteins in the induction of p21WAF1,Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells.
Topics: Blotting, Northern; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Breast Neoplasms; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dactinomycin; Depression, Chemical; DNA-Binding Proteins; Female; Humans; Immunoblotting; RNA, Messenger; Smad Proteins; Smad1 Protein; Smad4 Protein; Trans-Activators; Transforming Growth Factor beta | 2002 |
Aurintricarboxylic acid induces a distinct activation of the IGF-I receptor signaling within MDA-231 cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Aurintricarboxylic Acid; Breast Neoplasms; Cell Death; Cycloheximide; Doxorubicin; Female; Humans; Phosphorylation; Protein Synthesis Inhibitors; Receptor, IGF Type 1; Ricin; Signal Transduction; Tumor Cells, Cultured | 2002 |
Mechanism of 17-beta-estradiol-induced Erk1/2 activation in breast cancer cells. A role for HER2 AND PKC-delta.
Topics: Blotting, Western; Breast Neoplasms; Cell Division; Cycloheximide; Disease Progression; DNA, Complementary; Enzyme Activation; ErbB Receptors; Estradiol; Genes, Dominant; Humans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Monomeric GTP-Binding Proteins; Neuregulin-1; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Protein Synthesis Inhibitors; Receptor, ErbB-2; Signal Transduction; Time Factors; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2002 |
Differential effects of fibroblast growth factors on expression of genes of the plasminogen activator and insulin-like growth factor systems by human breast fibroblasts.
Topics: Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Induction; Female; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Nucleic Acid Synthesis Inhibitors; Plasminogen Activator Inhibitor 1; Plasminogen Activator Inhibitor 2; Plasminogen Activators; Polymerase Chain Reaction; Protein Biosynthesis; Protein Isoforms; Protein Synthesis Inhibitors; Receptors, Somatomedin; RNA, Messenger; RNA, Neoplasm; Serine Endopeptidases; Somatomedins; Transcription, Genetic | 2002 |
[Effect of calcium on steroidogenesis in isolated human adrenal cells (author's transl)].
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Breast Neoplasms; Bucladesine; Calcium; Cells, Cultured; Cushing Syndrome; Cycloheximide; Dose-Response Relationship, Drug; Female; Humans; Hyperaldosteronism; Male | 1975 |
Insulin stimulation of fatty acid synthesis in human breast cancer in long term tissue culture.
Topics: Acetates; Breast Neoplasms; Cells, Cultured; Cycloheximide; Dactinomycin; Dihydrotestosterone; Estradiol; Female; Glucose; Humans; Insulin; Lipids | 1977 |
Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines.
Topics: Amino Acid Sequence; Animals; Base Sequence; Breast; Breast Neoplasms; Cell Communication; Cell Cycle; Cell Line; Connexin 26; Connexins; Cycloheximide; Dactinomycin; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Intercellular Junctions; Membrane Proteins; Molecular Sequence Data; Nucleic Acid Hybridization; Rats; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Regulation of insulin receptor gene expression. Cell cycle-mediated effects on insulin receptor mRNA stability.
Topics: Actins; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cycloheximide; Dactinomycin; DNA Probes; Exons; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Kinetics; Liver Neoplasms; Receptor, Insulin; Restriction Mapping; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Down-regulation of messenger ribonucleic acid (mRNA) for the estrogen receptor (ER) by phorbol ester requires ongoing RNA synthesis but not protein synthesis. Is hormonal control of ER mRNA degradation mediated by an RNA molecule?
Topics: Breast Neoplasms; Carcinoma; Cycloheximide; Dactinomycin; Dichlororibofuranosylbenzimidazole; Hormones; Humans; Puromycin; Receptors, Estrogen; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Regulation of c-jun and jun-B by progestins in T-47D human breast cancer cells.
Topics: beta-Galactosidase; Blotting, Northern; Blotting, Western; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Cycloheximide; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Genes, jun; Humans; Kinetics; Medroxyprogesterone Acetate; Multigene Family; Proto-Oncogene Proteins c-jun; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1992 |
Interleukin-1 is a motility factor for human breast carcinoma cells in vitro: additive effect with interleukin-6.
Topics: Breast Neoplasms; Cell Membrane; Cell Movement; Cell Size; Culture Media, Conditioned; Cycloheximide; Drug Interactions; Female; Humans; Image Processing, Computer-Assisted; Interleukin-1; Interleukin-6; Pertussis Toxin; Recombinant Proteins; Tumor Cells, Cultured; Video Recording; Virulence Factors, Bordetella | 1992 |
Effect of sodium butyrate on estrogen receptor and epidermal growth factor receptor gene expression in human breast cancer cell lines.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Cycloheximide; DNA Probes; ErbB Receptors; Female; Gene Expression; Humans; Kinetics; Receptors, Estrogen; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Bombesin and glucocorticoids stimulate human breast cancer cells to produce endothelin, a paracrine mitogen for breast stromal cells.
Topics: Bombesin; Breast; Breast Neoplasms; Cell Line; Cells, Cultured; Cycloheximide; DNA Replication; Dose-Response Relationship, Drug; Endothelins; Female; Fibroblasts; Humans; Hydrocortisone; Inositol Phosphates; Kinetics; Thymidine | 1992 |
Identification of albumin in breast tumor cytosol as a factor involved in the stimulation of estradiol 17 beta-hydroxysteroid dehydrogenase (reductive) activity.
Topics: Breast Neoplasms; Charcoal; Chromatography, Gel; Cycloheximide; Cytosol; Enzyme Activation; Estradiol Dehydrogenases; Hot Temperature; Humans; Kinetics; Oxidation-Reduction; Serum Albumin | 1992 |
Modulation of oestrone sulphatase activity in breast cancer cell lines by growth factors.
Topics: Breast Neoplasms; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Female; Fibroblast Growth Factor 2; Humans; Insulin-Like Growth Factor I; Kinetics; Sulfatases | 1992 |
Expression of pS2 gene in human breast cancer cell line MCF-7 is controlled by retinoic acid.
Topics: Breast Neoplasms; Cycloheximide; Female; Gene Expression Regulation, Neoplastic; Humans; RNA, Messenger; RNA, Neoplasm; Tretinoin; Tumor Cells, Cultured | 1992 |
Serum and insulin inhibit cell death induced by cycloheximide in the human breast cancer cell line MCF-7.
Topics: Blood Proteins; Breast Neoplasms; Cell Death; Cycloheximide; Cytotoxins; Dose-Response Relationship, Drug; Humans; Insulin; L-Lactate Dehydrogenase; Leucine; Proteins; Time Factors; Tritium; Trypan Blue; Tumor Cells, Cultured | 1992 |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH, E.C. 1.2.1.12.) gene expression in two malignant human mammary epithelial cell lines: BT-20 and MCF-7. Regulation of gene expression by 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3).
Topics: Breast Neoplasms; Calcitriol; Cycloheximide; DNA Probes; DNA, Neoplasm; Epithelium; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Kinetics; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Butyrates; Butyric Acid; Cycloheximide; Dactinomycin; Gene Expression Regulation; Humans; Kinetics; Receptors, Prolactin; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Effects of hormones on SBP mRNA levels in human cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cycloheximide; Endometrial Neoplasms; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Insulin; Liver Neoplasms; Male; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Sex Hormone-Binding Globulin; Steroids; Triiodothyronine; Tumor Cells, Cultured | 1991 |
Stimulation of 1,25-dihydroxyvitamin D3 receptor gene expression in cultured cells by serum and growth factors.
Topics: Animals; Binding Sites; Blood; Blotting, Northern; Breast Neoplasms; Calcitriol; Cell Division; Cell Line; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Growth Substances; Humans; Insulin; Insulin-Like Growth Factor I; Kinetics; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation | 1991 |
Interferon-alpha and gamma mediated gene responses in a human breast carcinoma cell line.
Topics: Blotting, Northern; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Cycloheximide; Dose-Response Relationship, Immunologic; Gene Expression Regulation, Neoplastic; Humans; Interferon Type I; Interferon-gamma; RNA; Transcriptional Activation; Tumor Cells, Cultured | 1991 |
Tumor necrosis factor alpha induces apoptosis in mammary adenocarcinoma cells by an increase in intranuclear free Ca2+ concentration and DNA fragmentation.
Topics: Adenocarcinoma; Breast Neoplasms; Calcium; Cell Death; Cycloheximide; DNA Damage; DNA, Neoplasm; Humans; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Progestin regulation of alkaline phosphatase in the human breast cancer cell line T47D.
Topics: Acid Phosphatase; Alkaline Phosphatase; Breast Neoplasms; Cell Line; Cycloheximide; Enzyme Induction; Female; Humans; Kinetics; Organ Specificity; Promegestone; Steroids; Tunicamycin | 1991 |
Increased epidermal growth factor receptor gene expression by gamma-interferon in a human breast carcinoma cell line.
Topics: Breast Neoplasms; Cell Line; Cycloheximide; Dactinomycin; ErbB Receptors; Female; Gene Expression; Humans; Interferon-gamma; Kinetics; RNA, Messenger; Transcription, Genetic | 1991 |
Direct transcriptional regulation of the progesterone receptor by retinoic acid diminishes progestin responsiveness in the breast cancer cell line T-47D.
Topics: Breast Neoplasms; Cycloheximide; Gene Expression Regulation; Half-Life; Immunoblotting; Kinetics; Progesterone; Receptors, Progesterone; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1991 |
Enhanced glycosyltransferase activity during thermotolerance development in mammalian cells.
Topics: Animals; Arsenic; Arsenites; beta-D-Galactoside alpha 2-6-Sialyltransferase; Breast Neoplasms; Cell Line; Cricetinae; Cycloheximide; Dactinomycin; Diamide; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Galactosyltransferases; Heat-Shock Proteins; Hot Temperature; Humans; Kinetics; N-Acetylgalactosaminyltransferases; Sialyltransferases; Sodium Compounds; Tumor Cells, Cultured | 1990 |
Transcriptional regulation of DF3 gene expression in human MCF-7 breast carcinoma cells.
Topics: Antigens, Neoplasm; Blotting, Northern; Breast Neoplasms; Cycloheximide; Dactinomycin; Gene Expression Regulation; Glycoproteins; Humans; Molecular Weight; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
A difference in the regulation of mRNA expression between the phenotypic and the embryonic alkaline phosphatase genes in human cancer cells.
Topics: Alkaline Phosphatase; Breast Neoplasms; Calcitriol; Cycloheximide; Dexamethasone; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Isoenzymes; Nucleic Acid Hybridization; Placenta; RNA, Messenger; Tumor Cells, Cultured | 1990 |
Progestin increases gene transcription and messenger ribonucleic acid stability of fatty acid synthetase in breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Cell Count; Cycloheximide; Electrophoresis, Agar Gel; Fatty Acid Synthases; Humans; RNA; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Stimulation of estrogen receptor mRNA levels in MCF-7 cells by herpes simplex virus infection.
Topics: Blotting, Northern; Breast Neoplasms; Cycloheximide; Gene Expression Regulation; Herpes Simplex; Humans; Receptors, Estrogen; RNA, Messenger; Simplexvirus; Tumor Cells, Cultured; Viral Proteins | 1989 |
Induction of manganese superoxide dismutase by tumor necrosis factor in human breast cancer MCF-7 cell line and its TNF-resistant variant.
Topics: Breast Neoplasms; Cell Division; Cycloheximide; Cytosol; Dactinomycin; Drug Resistance; Enzyme Induction; Humans; Interleukin-1; Kinetics; Manganese; Mitochondria; Mutation; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Superoxide Dismutase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1989 |
Recycling of tumor necrosis factor-alpha receptor in MCF-7 cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Membrane; Cycloheximide; Endocytosis; Humans; Iodine Radioisotopes; Kinetics; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1989 |
Role of an estrogen receptor-dependent mechanism in the regulation of estrogen receptor mRNA in MCF-7 cells.
Topics: Breast Neoplasms; Cell Nucleus; Cycloheximide; Cytoplasm; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Hormone-Dependent; Receptors, Estrogen; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Tamoxifen; Tumor Cells, Cultured | 1989 |
Regulation of cathepsin-D and pS2 gene expression by growth factors in MCF7 human breast cancer cells.
Topics: Breast Neoplasms; Cathepsin D; Cycloheximide; Dose-Response Relationship, Drug; Epidermal Growth Factor; Estradiol; Fibroblast Growth Factors; Gene Expression Regulation; Growth Substances; Humans; Insulin; Insulin-Like Growth Factor I; Neoplasm Proteins; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1989 |
Hormonal regulation of synthesis and secretion of pS2 protein relevant to growth of human breast cancer cells (MCF-7).
Topics: Androgens; Breast Neoplasms; Cell Division; Cycloheximide; Dactinomycin; DNA, Neoplasm; Estrogens; Humans; In Vitro Techniques; Nafoxidine; Neoplasm Proteins; Progesterone; Proteins; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1989 |
Early estrogen-induced metabolic changes and their inhibition by actinomycin D and cycloheximide in human breast cancer cells: 31P and 13C NMR studies.
Topics: Breast Neoplasms; Carbon Isotopes; Cell Line; Clone Cells; Cycloheximide; Dactinomycin; Estradiol; Female; Glucose; Glutamates; Glycolysis; Humans; Lactates; Magnetic Resonance Spectroscopy; Phospholipids; Phosphorus; Tamoxifen; Tumor Cells, Cultured | 1989 |
Up-regulation of estrogen receptors by nonsteroidal antiestrogens in human breast cancer.
Topics: Breast Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Humans; Receptors, Estrogen; Tamoxifen; Time Factors | 1989 |
Regulation of the 1,25-dihydroxyvitamin D3 receptor by 1,25-dihydroxyvitamin D3 in intact human cancer cells.
Topics: Breast Neoplasms; Calcitriol; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyadenosines; Humans; Puromycin; Receptors, Calcitriol; Receptors, Steroid; Time Factors; Tritium | 1985 |
Modulation of lactogenic receptors by progestins in cultured human breast cancer cells.
Topics: Breast Neoplasms; Cell Line; Cycloheximide; Estradiol; Female; Growth Hormone; Hormones; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Progestins; Receptors, Cell Surface; Receptors, Peptide; Receptors, Progesterone; Receptors, Somatotropin | 1986 |
1,25-Dihydroxyvitamin D3 exerts opposite effects on the regulation of human embryonic and nonembryonic alkaline phosphatase isoenzymes.
Topics: Alkaline Phosphatase; Breast Neoplasms; Calcitriol; Cell Line; Cycloheximide; Dexamethasone; Humans; Hydrocortisone; In Vitro Techniques; Isoenzymes; Radioimmunoassay; Receptors, Calcitriol; Receptors, Glucocorticoid; Receptors, Steroid | 1987 |
Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Cycloheximide; Cytotoxins; Dactinomycin; Female; Glycoproteins; Humans; Interferon-gamma; Melanoma; Neoplasm Proteins; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tumor Necrosis Factor-alpha; Uterine Cervical Neoplasms | 1987 |
Transcriptional regulation of c-myc oncogene expression by estrogen in hormone-responsive human breast cancer cells.
Topics: Breast Neoplasms; Cycloheximide; Dactinomycin; DNA; Estradiol; Gene Expression Regulation; Half-Life; Humans; Nucleic Acid Hybridization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured | 1988 |
Hormonal modulation of plasminogen activator: an approach to prediction of human breast tumor responsiveness.
Topics: Adenylyl Cyclases; Breast Neoplasms; Cell Survival; Cycloheximide; Estradiol; Humans; Hydrocortisone; In Vitro Techniques; Plasminogen Activators; Plasminogen Inactivators; Progesterone; Prolactin; Receptors, Estrogen; Receptors, Progesterone; Triiodothyronine | 1987 |
Estrogen-induced post-transcriptional modulation of c-myc proto-oncogene expression in human breast cancer cells.
Topics: Breast Neoplasms; Cycloheximide; Estradiol; Exons; Gene Expression Regulation; Humans; Introns; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1988 |
Estrogen receptor distribution in enucleated breast cancer cell lines.
Topics: Breast Neoplasms; Cell Fractionation; Cell Nucleus; Cycloheximide; Cytoplasm; DNA; Enzyme-Linked Immunosorbent Assay; Estradiol; Humans; Phenolsulfonphthalein; Proteins; Radioligand Assay; Receptors, Estrogen; Tumor Cells, Cultured | 1988 |
Recombinant human leukocyte interferon-alpha 2b stimulates the synthesis and release of a 90K tumor-associated antigen in human breast cancer cells.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Breast Neoplasms; Cells, Cultured; Cycloheximide; Female; Humans; Interferon Type I; Molecular Weight; Recombinant Proteins | 1988 |
Modulation of epidermal growth factor receptor gene expression by transforming growth factor-beta in a human breast carcinoma cell line.
Topics: Breast Neoplasms; Carcinoma; Cell Line; Cycloheximide; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation; Humans; Kinetics; Peptides; RNA, Messenger; Transforming Growth Factors | 1987 |
Relationship between the expression of estrogen-regulated genes and estrogen-stimulated proliferation of MCF-7 mammary tumor cells.
Topics: Amanitins; Breast Neoplasms; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; DNA, Neoplasm; Estradiol; Estrogens; Female; Genes; Humans; Kinetics; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Tetrahydrofolate Dehydrogenase; Thymidine Kinase | 1985 |
Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells treated with adenosine-3':5'-cyclic monphosphate and its derivatives.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Breast Neoplasms; Butyrates; Cell Line; Choriocarcinoma; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Pregnancy | 1971 |