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cycloheximide and Acute Liver Injury, Drug-Induced

cycloheximide has been researched along with Acute Liver Injury, Drug-Induced in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199020 (76.92)18.7374
1990's2 (7.69)18.2507
2000's3 (11.54)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujinaga, M; Hatori, A; Kawamura, K; Kumata, K; Nengaki, N; Ogawa, M; Wakizaka, H; Xie, L; Yamasaki, T; Yui, J; Zhang, MR1
Ando, Y; Hakamata, S; Ito, K; Kumagai, K; Manabe, S; Nakayama, H; Teranishi, M1
Blankenberg, FG; Levashova, Z; Patel, B; Smith, C; Tait, JF; Vanderheyden, JL1
Ito, K; Kiyosawa, N; Kumagai, K; Manabe, S; Nakayama, H; Teranishi, M; Yamoto, T1
Schmerold, I; Tempel, K1
Kojima, S; Kubodera, A; Sasaki, T1
Parry, EW2
Castro, JA; Díaz Gómez, MI; Galelli, M1
Farber, E; Popp, JA; Shinozuka, H1
Guzelian, PS; Luoma, PV1
Faus, MJ; Lupiáñez, A; Sánchez-Medina, F; Vargas, A1
Castro, JA; de Castro, CR; de Fenos, OM; Diaz Gómez, MI; Ferreyra, EC; Gram, TE; Guarino, AM; Reagan, RL1
Anders, MW; Lindstrom, TD1
Connelly, LJ; Koff, RS1
Flaks, B; O'Connor, JA; Wilks, PN1
Columbano, A; Coni, P; Curto, M; Faa, G; Giacomini, L; Ledda-Columbano, GM; Oliverio, S; Piacentini, M1
Pappas, NJ1
Keiser, HR; Sjoerdsma, A; Stein, HD1
Albring, M; Rumpelt, HJ1
Gravela, E1
García-Ruiz, JP; Mayor, F; Moreno, F; Sánchez-Medina, F1
Abbritti, G; De Matteis, F; Gibbs, AH1
Bertolino, A; Giovine, A; Renis, M; Rizzi, MM1
Indacochea-Redmond, N; Plaa, GL; Witschi, H1
Farber, E; Liang, H; Shinozuka, H1

Other Studies

26 other study(ies) available for cycloheximide and Acute Liver Injury, Drug-Induced

ArticleYear
Visualization of acute liver damage induced by cycloheximide in rats using PET with [(18)F]FEDAC, a radiotracer for translocator protein (18 kDa).
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Acetamides; Animals; Carrier Proteins; Chemical and Drug Induced Liver Injury; Cycloheximide; Immunoenzyme Techniques; Male; Positron-Emission Tomography; Protein Synthesis Inhibitors; Protein Transport; Purines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution

2014
Neutralization of IL-10 exacerbates cycloheximide-induced hepatocellular apoptosis and necrosis.
    Toxicologic pathology, 2009, Volume: 37, Issue:4

    Topics: Animals; Antibodies; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytokines; Data Interpretation, Statistical; Hepatocytes; Interleukin-10; Liver; Liver Diseases; Male; Necrosis; Neutralization Tests; Neutrophil Infiltration; Rats; Rats, Inbred F344; RNA, Messenger; Signal Transduction; Up-Regulation

2009
Improved detection of cell death in vivo with annexin V radiolabeled by site-specific methods.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:9

    Topics: Animals; Annexin A5; Apoptosis; Binding Sites; Chemical and Drug Induced Liver Injury; Cycloheximide; Isotope Labeling; Liver; Liver Diseases; Mice; Mice, Inbred BALB C; Models, Biological; Organotechnetium Compounds; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals

2006
Influence of Kupffer cell inactivation on cycloheximide-induced hepatic injury.
    Toxicology, 2007, Nov-30, Volume: 241, Issue:3

    Topics: Animals; Antigens, CD; Apoptosis; Chemical and Drug Induced Liver Injury; Cycloheximide; Gadolinium; Gene Expression; Gene Expression Profiling; Hepatocytes; In Situ Nick-End Labeling; Kupffer Cells; Liver Function Tests; Male; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction

2007
[DNase II activation in rat liver in the course of acute diethylnitrosamine-induced damage (author's transl)].
    Archives of toxicology, 1981, Volume: 48, Issue:2-3

    Topics: Animals; Cell Nucleus; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytosol; Deoxyribonucleases; Diethylnitrosamine; Endodeoxyribonucleases; Endonucleases; Enzyme Activation; In Vitro Techniques; Liver Diseases; Male; Nitrosamines; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA

1981
[Uptake of 67Ga into the rat liver after treatment with thioacetamide].
    Radioisotopes, 1984, Volume: 33, Issue:9

    Topics: Acetamides; Animals; Cell Differentiation; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytarabine; DNA; Gallium Radioisotopes; Heparitin Sulfate; Liver; Male; Rats; Thioacetamide; Thymidine

1984
The effect of cycloheximide and carbon tetrachloride in Ehrlich ascites tumour-bearing mice.
    Gan, 1980, Volume: 71, Issue:3

    Topics: Animals; Carbon Tetrachloride; Carcinoma, Ehrlich Tumor; Chemical and Drug Induced Liver Injury; Cycloheximide; Liver; Male; Mice; Mice, Inbred CBA; Necrosis; Protein Biosynthesis

1980
Decreased incorporation of 14C-leucine in different liver nuclear protein fractions at early stages of carbon tetrachloride poisoning in the rat.
    Archives of toxicology, 1994, Volume: 68, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Histones; Leucine; Liver; Male; Microsomes, Liver; Nuclear Proteins; Rats; Rats, Sprague-Dawley

1994
The protective effects of diethyldithiocarbamate and cycloheximide on the multiple hepatic lesions induced by carbon tetrachloride in the rat.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Ditiocarb; Liver; Male; Rats; Thiocarbamates; Time Factors

1978
Lysosomal enzymes in hepatic injury induced by bromobenzene.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1978, Issue:1

    Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cycloheximide; Lysosomes; Male; Rats

1978
The mechanism of necrotic tissue removal in mouse liver following CCl4-induced injury.
    Journal of comparative pathology, 1979, Volume: 89, Issue:2

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cycloheximide; Eosinophils; Liver; Male; Mice; Necrosis; Protease Inhibitors; Protein Biosynthesis

1979
Induction of rat kidney gluconeogenesis during acute liver intoxication by carbon tetrachloride.
    The Biochemical journal, 1978, Aug-15, Volume: 174, Issue:2

    Topics: Acute Disease; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Dactinomycin; Enzyme Activation; Female; Gluconeogenesis; In Vitro Techniques; Kidney; Liver; Liver Diseases; Phosphoenolpyruvate Carboxykinase (GTP); Rats

1978
Studies on the role of protein syntheis in cell injury by toxic agents: I. Effect of cycloheximide administration on several factors modulating carbon tetrachloride-induced liver necrosis.
    Toxicology and applied pharmacology, 1977, Volume: 41, Issue:2

    Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytochrome Reductases; Drug Interactions; Lipid Metabolism; Liver; Liver Diseases; Male; Microsomes, Liver; Necrosis; Pentobarbital; Peroxides; Polyribosomes; Rats; Sleep; Time Factors

1977
Effect of cycloheximide and actinomycin D on carbon tetrachloride hepatotoxicity.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytochrome P-450 Enzyme System; Dactinomycin; Lipid Metabolism; Liver; Male; Microsomes, Liver; Proteins; Rats; Time Factors; Triglycerides

1977
Modification of the hepatotoxicity of D-galactosamine in the rat by cycloheximide.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 151, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cycloheximide; Galactosamine; Liver; Liver Diseases; Necrosis; Protein Biosynthesis; Rats; Triglycerides

1976
Modification of toxic liver injury in the rat. III. Fine structure of hepatocytes during cycloheximide protection and autoprotection in acute ethionine intoxication.
    Toxicology and applied pharmacology, 1976, Volume: 35, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Ethionine; Liver; Male; Rats; Rats, Inbred Strains; Time Factors

1976
Induction of two different modes of cell death, apoptosis and necrosis, in rat liver after a single dose of thioacetamide.
    The American journal of pathology, 1991, Volume: 139, Issue:5

    Topics: Alanine Transaminase; Animals; Cell Death; Chemical and Drug Induced Liver Injury; Cycloheximide; Dose-Response Relationship, Drug; Immunohistochemistry; Liver; Liver Regeneration; Male; Microscopy, Electron; Nafenopin; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors; Transglutaminases

1991
Source of increased serum aspartate and alanine aminotransferase: cycloheximide effect on carbon tetrachloride hepatotoxicity.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Feb-15, Volume: 154, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Cytosol; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains

1986
The effects of anesthetic agents of serum proline hydroxylase.
    Anesthesiology, 1972, Volume: 36, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Anesthesia, General; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cycloheximide; Enzyme Induction; Liver; Male; Methoxyflurane; Mixed Function Oxygenases; Nitrous Oxide; Procollagen-Proline Dioxygenase; Rabbits

1972
[Proceedings: Inhibition of autophagocytosis through cycloheximide in rat hepatocytes damaged by D-galactosamine].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1974, Volume: 58

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Galactosamine; Liver; Phagocytosis; Rats

1974
Evidence for a reduced active life-span of messenger RNA in liver of rats poisoned with carbon tetrachloride.
    Experimental and molecular pathology, 1973, Volume: 19, Issue:1

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Dactinomycin; Liver; Male; Orotic Acid; Polyribosomes; Rats; RNA, Messenger; RNA, Ribosomal; Tritium

1973
Stimulation of rat kidney phosphoenolpyruvate carboxykinase activity in experimental liver disease induced by galactosamine.
    FEBS letters, 1973, Aug-01, Volume: 34, Issue:1

    Topics: Animals; Bicarbonates; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Cycloheximide; Female; Galactosamine; Glucose; In Vitro Techniques; Kidney; Lactates; Liver; Perfusion; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Starvation; Time Factors

1973
Decreased liver activity of porphyrin-metal chelatase in hepatic porphyria caused by 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Studies in rats and mice.
    The Biochemical journal, 1973, Volume: 134, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Dicarboxylic Acids; Heme; Iron; Iron Radioisotopes; Levulinic Acids; Liver Diseases; Lyases; Male; Mice; Mitochondria, Liver; Porphyrias; Porphyrins; Proadifen; Pyridines; Rats; Species Specificity

1973
[Ethanol-induced changes in protein synthesis of mitochondria and microsomes of rat brain and liver].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Sep-15, Volume: 49, Issue:17

    Topics: Alcoholic Intoxication; Animals; Brain; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cycloheximide; Ethanol; Humans; Leucine; Liver; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Protein Biosynthesis; Rats

1973
Effects of inhibitors of protein and ribonucleic acid synthesis on naphthyliso-thiocyanate-induced hyperbilirubinemia, sulfobromophthalein retention and prolongation of pentobarbital hypnosis.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cycloheximide; Dactinomycin; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Ethionine; Female; Hyperbilirubinemia; Male; Pentobarbital; Protein Biosynthesis; Rats; RNA; Sex Factors; Sleep; Sulfobromophthalein; Thiocyanates; Time Factors

1974
Dissociation of effects on protein synthesis and ribosomes from membrane changes induced by carbon tetrachloride.
    The American journal of pathology, 1971, Volume: 64, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Endoplasmic Reticulum; Ethionine; Liver; Metabolism; Microscopy, Electron; Mineral Oil; Protein Biosynthesis; Puromycin; Rats; Ribosomes; Sodium Chloride

1971