cyclohexanol has been researched along with Disease Models, Animal in 126 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.79) | 18.2507 |
| 2000's | 45 (35.71) | 29.6817 |
| 2010's | 80 (63.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baranowska-Kuczko, M; Harasim-Symbor, E; Kasacka, I; Malinowska, B; Pędzińska-Betiuk, A; Toczek, M; Weresa, J | 1 |
| Bedse, G; Gaulden, AD; Hartley, ND; Kingsley, PJ; Marnett, LJ; Neale, E; Patel, S; Patrick, TA; Plath, N; Uddin, MJ | 1 |
| Bonin, RP; De Koninck, Y; Echeverry, S; Huang, H; Lorenzo, LE; Perez-Sanchez, J; Shi, XQ; Wu, Y; Yang, M; Zhang, J | 1 |
| Ardashov, O; Ivanova, Е; Kapitsa, I; Khazanov, V; Salakhutdinov, N; Valdman, E; Volcho, K; Voronina, TI | 1 |
| Henderson-Redmond, AN; LaFleur, RA; Morgan, DJ; Wilson, RP | 1 |
| Alcântara, IS; da Costa, JGM; da Silva, BAF; da Silva, MDS; da Silva, TG; de Lima, SG; de Menezes, IRA; de Oliveira, MRC; Fernandes, MNM; Kerntopf, MR; Martins, AOBPB; Oliveira-Tintino, CDM; Pessoa, RT; Rodrigues, FFG; Tintino, SR | 1 |
| Giménez-Llort, L; Giralt, MT; Ledent, C; Llorente-Ovejero, A; Lombardero, L; Manuel, I; Rodríguez-Puertas, R | 1 |
| Alshehri, FS; Hakami, AY; Sari, Y | 1 |
| Aerts, JMFG; Artola, M; Futerman, AH; Kallemeijn, WW; Kuo, CL; Lelieveld, LT; Meijer, AH; Mirzaian, M; Overkleeft, HS; Spaink, HP; Vardi, A; Zoutendijk, I | 1 |
| Aerts, JMFG; Artola, M; Boot, RG; Codée, JDC; Davies, GJ; Kuo, CL; Lelieveld, LT; Overkleeft, HS; Rowland, RJ; van der Marel, GA | 1 |
| Chen, S; Feng, ZP; Guo, Z; Huang, J; Mu, N; Wang, H; Wang, R; Wen, Q; Zheng, W; Zhou, X | 1 |
| Alén, F; de Fonseca, FR; de Heras, RG; Gorriti, MÁ; Orio, L; Pozo, MÁ; Ramírez-López, MT | 1 |
| Catlow, JT; Ding, C; Gleason, SD; Heinz, B; Leucke, S; Li, X; Lynch, RA; Thompson, LK; Witkin, JM | 1 |
| Charoenphandhu, J; Charoenphandhu, N; Lapmanee, S | 1 |
| Ago, Y; Fujita, K; Hiramatsu, N; Kawanai, T; Matsuda, T; Takuma, K; Umehara, M | 1 |
| Chen, JD; Dai, F; Lei, Y; Li, S; Song, G | 1 |
| Aggarwal, BB; Gupta, SC; Li, S; Yuan, W | 1 |
| Bijlsma, EY; Chan, JS; Millan, MJ; Olivier, B; Oosting, RS; Veening, JG; Waldinger, MD | 1 |
| Fang, C; Sun, J; Tang, F; Zhao, C | 1 |
| Ali, J; Baboota, S; Haque, S; Md, S; Sahni, JK | 1 |
| Ahad, A; Ali, A; Aqil, M | 1 |
| Jagla, G; Makuch, W; Mika, J; Obara, I; Przewlocka, B; Wordliczek, J | 1 |
| Guo, H; Guo, W; Hartle, K; He, J; Huang, Q; Kong, J; Li, XM; Qiao, J; Wang, H; Wang, J; Zhang, H; Zhang, Y; Zhu, S | 1 |
| Bauer, R; Brodhun, M; Brust, P; Deuther-Conrad, W; Donat, CK; Fischer, F; Walter, B | 1 |
| Huang, X; Ji, JL; Li, C; Mao, YS; Wang, H | 1 |
| Hou, J; Meng, Q; Tian, J; Wu, Y; Xing, Y; Yang, M; Zuo, D | 1 |
| Dikshit, M; Shukla, S; Singh, KP; Singh, M | 1 |
| Barry, M; Gilbert, K; Godbout, R; Malick, M; Rousseau, G | 1 |
| Kim, KY; Lee, HS; Seol, GH | 1 |
| Cornett, BL; Deng, L; Hohmann, AG; Mackie, K | 1 |
| Jay, TM; Krebs, MO; Le Pen, G; Lenkei, Z; Rame, M; Renard, J; Vitalis, T | 1 |
| Giuffrida, A; Seillier, A | 1 |
| Borea, PA; Canazza, I; De Luca, MA; Marti, M; Ossato, A; Rimondo, C; Serpelloni, G; Trapella, C; Varani, K; Vincenzi, F | 1 |
| Gupta, K; Gupta, M; Jahagirdar, B; Lamarre, Y; Mittal, A | 1 |
| Bakali, E; Elliott, RA; Lambert, DG; Mason, R; Mbaki, Y; Tincello, DG | 1 |
| Liu, Q; Meng, X; Shao, J; Tian, J; Wang, H; Ye, L; Zhang, F; Zhong, Y | 1 |
| Cho, SH; Kang, HR; Lee, HS; Park, DE; Park, HW; Sohn, SW; Song, WJ | 1 |
| Abdallah, HM; Ali, SS; Murad, HA | 1 |
| Barroso, MV; Brito-Gitirana, L; Kennedy-Feitosa, E; Lanzetti, M; Okuro, RT; Pinho Ribeiro, V; Porto, LC; Valenca, SS; Zin, WA | 1 |
| de Almeida, RN; de Sousa, DP; Fonsêca, DV; Monte, LO; Salgado, PR; Souto-Maior, FN | 1 |
| Kim, KY; Seol, GH | 1 |
| Armani, A; Bernardes, SS; Borges, FH; Cecchini, AL; Cecchini, R; Da Silva, TNX; Guarnier, FA; Lopes, NMD; Marinello, PC; Simão, ANC | 1 |
| Cooper, TB; Hungund, BL; Thanos, PK; Vadasz, C; Vinod, KY; Volkow, ND; Yalamanchili, R | 1 |
| Carrier, EJ; Gorzalka, BB; Hill, MN; Hillard, CJ; McLaughlin, RJ; Meier, SE; Morrish, AC | 1 |
| Kálmán, J | 1 |
| Dhir, A; Kulkarni, SK | 2 |
| Berlanga, C; Estrada-Camarena, E; Fernández-Guasti, A; Rivera, NM | 1 |
| Alexander, M; Burton, NC; Griswold, M; Guilarte, TR; McGlothan, JL; Pham, L; Schneider, JS; Syversen, T; Verina, T; Wong, DF; Zhou, Y | 1 |
| Díaz, A; Pazos, A; Rodríguez-Gaztelumendi, A; Rojo, ML | 1 |
| Batista, FJ; De Sousa, CM; Fonteles, MC; Kerntopf, MR; Nascimento, NR; Refosco, RM; Santos, CF; Vasconcelos, EC | 1 |
| Kane, SA; Liang, A; Sain, NM; Urban, MO | 1 |
| Garg, R; Gaur, V; Kumar, A; Kumar, P | 1 |
| Berrendero, F; Burokas, A; Gispert, JD; Heyne, A; Kiesselbach, C; Maldonado, R; Martín, M; Martín-García, E; Millán, O; Rubí, B | 1 |
| Obara, I; Przewlocka, B; Wordliczek, J; Wrzosek, A | 1 |
| Hay-Schmidt, A; Larsen, MH; Mikkelsen, JD; Sandi, C | 1 |
| Ericson, ME; Gupta, K; Gupta, P; Gupta, V; Hebbel, RP; Kehl, LJ; Khasabov, SG; Kohli, DR; Li, Y; Nguyen, J; Simone, DA | 1 |
| Gaur, V; Kumar, A | 1 |
| Darlington, CL; Hamilton, E; Smith, PF; Stiles, L; Zheng, Y | 1 |
| Arnold, JC; Boucher, AA; Huang, X; Hunt, GE; Karl, T; McGregor, IS; Micheau, J | 1 |
| Krass, M; Vasar, E; Volke, V; Wegener, G | 1 |
| Fowler, CJ; Rojo, ML; Söderström, I | 1 |
| Inoue, K; Takano, H | 1 |
| Dhir, A; Kessar, SV; Kulkarni, SK; Malik, S; Singh, KN | 1 |
| Fernández-Ruiz, J; García, C; García-Arencibia, M; Palomo-Garo, C; Pertwee, R; Ramos, J | 1 |
| Amenta, PS; Barbe, MF; Elliott, MB; Jallo, JI; Tuma, RF | 1 |
| de Almeida, AC; de-Faria, FM; Dunder, RJ; Hiruma-Lima, CA; Luiz-Ferreira, A; Manzo, LP; Pellizzon, CH; Rehen, CS; Rozza, AL; Salvador, MJ; Socca, EA; Souza-Brito, AR; Takayama, C; Valim-Araújo, Dde A | 1 |
| Ardashov, OV; Il'ina, IV; Karpova, EV; Korchagina, DV; Morozova, EA; Pavlova, AV; Salakhutdinov, NF; Tolstikova, TG; Volcho, KP | 1 |
| Bento, AF; Calixto, JB; Meotti, FC; Passos, GF; Paszcuk, AF; Silva, ES; Simão da Silva, KAB | 1 |
| Du, G; Gao, X; Guo, X; Li, Z; Qin, X; Sun, H; Zhang, L; Zheng, X; Zhou, Y | 1 |
| Abernethy, L; Ansari, N; Cameron, K; Clarkson, T; Dempster, M; Dunn, D; Easson, AM; Edwards, D; Everett, K; Feilden, H; Ho, KK; Kultgen, S; Littlewood, P; Maclean, J; McArthur, D; McGregor, D; McLuskey, H; Neagu, I; Nimz, O; Nisbet, LA; Ohlmeyer, M; Palin, R; Pham, Q; Ratcliffe, P; Rong, Y; Roughton, A; Sammons, M; Swanson, R; Tracey, H; Walker, G | 1 |
| Cure, MC; Demirdas, A; Eren, I; Kirbas, A; Sutcu, R; Yilmaz, M; Yilmaz, N | 1 |
| Bacq, A; Balasse, L; Biala, G; Chevarin, C; Gardier, AM; Gautron, S; Giros, B; Guiard, B; Hamon, M; Louis, F; Martres, MP; Schinkel, A; Vialou, V | 1 |
| Dai, MH; Han, Y; Li, DQ | 1 |
| Bello, NT; Coughlin, JW; Guarda, AS; Ladenheim, EE; Moran, TH; Redgrave, GW | 1 |
| Cain, DM; Gupta, K; Hebbel, RP; Simone, DA; Vang, D | 1 |
| Akhmetshina, A; Avouac, J; Bennett, BL; Beyer, C; Dees, C; Distler, JH; Distler, O; Horn, A; Lang, V; Palumbo, K; Reich, N; Schett, G; Tomcik, M; Xie, W; Zerr, P | 1 |
| Liu, MM; Shi, HS; Si, JJ; Sun, LL; Suo, L; Wu, P; Yang, CH; Yang, JL; Zhang, Y; Zhu, WL | 1 |
| Liu, J; Qiao, W; Ren, L; Sun, Y; Wang, S; Yang, Y | 1 |
| Cui, J; Du, GH; Gao, XX; Li, ZF; Li, ZY; Liu, XJ; Qin, XM; Sun, HF; Zhang, LZ; Zhou, YZ | 1 |
| Dykstra, H; Fan, S; Haskó, J; Krizbai, I; Mahadevan, A; McCormick, R; Persidsky, Y; Ramirez, SH; Reichenbach, N; Skuba, A; Son, YJ; Tuma, R; Zhang, M | 1 |
| Girbig, D; Igl, BW; Lehmann, T; Obendorf, M; Patchev, VK; Prelle, K | 1 |
| Santamaria-Cano, J | 1 |
| Delagrange, P; Elizalde, N; García-García, AL; Tordera, RM; Venzala, E | 1 |
| Liu, XH; Qin, J; Wang, Y; Wen, ZY; Yang, JL; Yu, JJ; Zhang, Y | 1 |
| Dang, SS; Galea, LA; Gorzalka, BB; Hill, MN; Hillard, CJ; McLaughlin, RJ; Wainwright, SR | 1 |
| Ardashov, OV; Korchagina, DV; Pavlova, AV; Salakhutdinov, NF; Tolstikova, Ty; Volcho, KP | 1 |
| Chernoff, D; Cross, JL; Harwig, C; Mackenzie, LF; MacRury, T; Raymond, J; Stenton, GR; Szabo, C; Tam, P; Toews, J | 1 |
| Aisa, B; Guereñu, G; Martisova, E; Ramírez, MJ | 1 |
| Feng, W; Fenli, S; Huande, L; Ronghua, Z | 1 |
| Ardashov, OV; Korchagina, DV; Pavlova, AV; Salakhutdinov, NF; Tolstikova, TG; Volcho, KP | 1 |
| Apelqvist, G; Bengtsson, F; Bergqvist, PB; Hjorth, S; Kullingsjö, J; Wikell, C | 1 |
| de Miguel, R; De Petrocellis, L; Di Marzo, V; Fernández-Ruiz, J; Lastres-Becker, I; Makriyannis, A | 1 |
| Manzanares, J; Oliva, JM; Ortiz, S; Palomo, T | 1 |
| Niederhoffer, N; Schmid, K; Szabo, B | 1 |
| Bari, M; Battista, N; Bernardi, G; Calabresi, P; Centonze, D; Finazzi-Agrò, A; Gubellini, P; Maccarrone, M; Picconi, B | 1 |
| Alloui, A; Ardid, D; Chapuy, E; Eschalier, A; Hernandez, A; Jourdan, D; Marchand, F; Pelissier, T | 1 |
| Dogru, A; Onal, A; Soykan, N; Uyar, M | 1 |
| Alloui, A; Alvarez, P; Ardid, D; Authier, N; Eschalier, A; Hernández, A; Marchand, F; Pelissier, T | 1 |
| Campos, AR; De Araújo, RP; Lima Júnior, RC; Rao, VS; Santos, FA; Silva, RM | 1 |
| Bo-Hua, Z; He, L; Hong-Ju, Y; Jun-Wei, W; Nan, Z; Wei-Guo, S; Wei-Xiu, Y; Zhe-Hui, G; Zheng-Hua, G; Zhi-Pu, L; Zhong-Wei, J | 1 |
| Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY | 1 |
| Cravatt, BF; Hillard, CJ; Patel, S | 1 |
| Boulet, JM; Chaffer, SM; Elsemore, DA; Gottshall, SL; Harrison, JE; Koetzner, L; Lee, G; Mark, L; Miller, W; Pearson, MS; Rabadi, L; Rotshteyn, Y; Shan, S; Tafesse, L; Toth, M; Turchin, PI; Valenzano, KJ; Whiteside, GT | 1 |
| Brain, C; Chen, A; Courade, JP; Dyson, A; Fox, A; Groarke, A; Loong, Y; Peacock, M; Yaqoob, M | 1 |
| Barnes, MJ; Daiss, JO; Mills, JS; Montana, JG; Showell, GA; Tacke, R; Warneck, JB | 1 |
| Aricioğlu, F; Buldanlioğlu, U; Ozyalçin, NS; Salanturoğlu, G | 1 |
| Chen, Z; Dyck, L; Haimanot, S; He, J; Li, X; Li, XM; Xu, H | 1 |
| Brown, ME; Chen, F; Cousins, JE; Darabie, AA; Fraser, PE; French, JE; Hawkes, CA; Kierstead, ME; Lambermon, MH; Lan, MF; McLaurin, J; Mount, HT; Phinney, AL; St George-Hyslop, P; Westaway, D; Wong, SS | 1 |
| Dunbar, GL; Lescaudron, L; Rossignol, J; Sandstrom, MI | 1 |
| Altunbaşak, A; Celik, O; Demirdaş, A; Eren, I; Naziroğlu, M; Ozmen, I; Uğuz, AC; Uz, E | 1 |
| Crim, J; Darmani, NA; Janoyan, JJ; Ramirez, J | 1 |
| Alemán-Lazarini, L; Arce-Popoca, E; Cabrales-Romero, Mdel P; Carrasco-Legleu, CE; Fatel-Fazenda, S; Márquez-Rosado, L; Sierra-Santoyo, A; Trejo-Solís, C; Villa-Treviño, S | 1 |
| Falsig, J; Geist, MA; Leist, M; Podhorna, J; Volbracht, C | 1 |
| Hajós, M; Hoffmann, WE; Kocsis, B | 1 |
| Boersen, AJ; Bombard, MC; Dey, ND; Dunbar, GL; Hulce, VD; Lescaudron, L; Lu, M; Myers, RA; Sandstrom, MI; York, LR | 1 |
| Alig, L; Alsenz, J; Andjelkovic, M; Bénardeau, A; Bendels, S; Bleicher, K; Bourson, A; David-Pierson, P; Guba, W; Hildbrand, S; Kube, D; Lübbers, T; Mayweg, AV; Narquizian, R; Neidhart, W; Nettekoven, M; Plancher, JM; Rocha, C; Rogers-Evans, M; Röver, S; Schneider, G; Taylor, S; Waldmeier, P | 1 |
| Atsumi, S; Iinuma, H; Nosaka, C; Umezawa, K | 1 |
| Massi, P; Parolaro, D; Rubino, T; Viganò, D | 1 |
| Rao, VS; Santos, FA | 1 |
| Fox, A; Gentry, C; James, I; Kesingland, A; McNair, K; Patel, S; Urban, L | 1 |
| De Freitas, LA; De Souza, VL; Pompeu, MM; Rao, VS; Santos, FA; Silva, RM; Teixeira, MJ; Tomé, AR | 1 |
| Bardotti, M; Parolaro, D; Poli, G; Ponti, W; Rubino, T | 1 |
| Bisogno, T; Capasso, F; Capasso, R; Di Marzo, V; Esposito, G; Fezza, F; Iuvone, T; Izzo, AA; Mascolo, N; Pinto, L | 1 |
| Bowen, WH; Harper, DS; Kohut, BE; Luo, D; Pearson, SK; Yu, D | 1 |
| Ahlner, J; Apelqvist, G; Baumann, P; Bengtsson, F; Eap, CB; Josefsson, M; Wikell, C | 1 |
6 review(s) available for cyclohexanol and Disease Models, Animal
| Article | Year |
|---|---|
Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Clinical Trials as Topic; Curcuma; Curcumin; Cyclohexanols; Disease Models, Animal; Furans; Heterocyclic Compounds, 2-Ring; Humans; Hypoglycemic Agents; Inflammation; Neoplasms; Sesquiterpenes; Sesquiterpenes, Germacrane | 2013 |
Sexual side effects of serotonergic antidepressants: mediated by inhibition of serotonin on central dopamine release?
Topics: Animals; Antidepressive Agents; Aza Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Buspirone; Cyclohexanols; Disease Models, Animal; Dopamine; Female; Humans; Indoles; Male; Norepinephrine; Paroxetine; Pyridines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Synaptic Transmission; Venlafaxine Hydrochloride | 2014 |
Eucalyptol and Its Role in Chronic Diseases.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Cyclohexanols; Disease Models, Animal; Drug Discovery; Eucalyptol; Eucalyptus; Humans; Monoterpenes; Phytotherapy; Plants, Medicinal; Signal Transduction | 2016 |
[Genomical and metabolomical abnormalities in Alzheimer disease and in experimental models].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antidepressive Agents; Apolipoprotein E4; Benzodiazepines; Citalopram; Cyclohexanols; Disease Models, Animal; Gene Expression Regulation; Humans; Hungary; Mianserin; Mirtazapine; Oxidative Stress; Polymorphism, Genetic; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride | 2008 |
[Diagnostic and therapeutic update in narcolepsy].
Topics: Adolescent; Adult; Age of Onset; Animals; Autoimmune Diseases; Benzhydryl Compounds; Cataplexy; Child; Clomipramine; Cyclohexanols; Delayed Diagnosis; Disease Models, Animal; Dogs; Genetic Predisposition to Disease; Histamine Agonists; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Hypothalamus; Immunoglobulins, Intravenous; Intracellular Signaling Peptides and Proteins; Methylphenidate; Modafinil; Narcolepsy; Neuropeptides; Orexins; Polysomnography; Receptors, Antigen, T-Cell; Sodium Oxybate; Venlafaxine Hydrochloride | 2012 |
Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: use of gangliosides, substituted pyrimidines, and mesenchymal stem cells.
Topics: Animals; Behavior, Animal; Brain; Cyclohexanols; Disease Models, Animal; Gangliosides; Humans; Huntington Disease; Mesoderm; Mice; Nerve Growth Factors; Neuroprotective Agents; Pluripotent Stem Cells; Pyrimidines; Stem Cell Transplantation; Up-Regulation | 2006 |
120 other study(ies) available for cyclohexanol and Disease Models, Animal
| Article | Year |
|---|---|
Chronic inhibition of fatty acid amide hydrolase by URB597 produces differential effects on cardiac performance in normotensive and hypertensive rats.
Topics: Amidohydrolases; Animals; Antihypertensive Agents; Benzamides; Blood Pressure; Carbamates; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Inbred SHR; Rats, Wistar; Structure-Activity Relationship | 2017 |
Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety.
Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Anxiety; Arachidonic Acids; Benzodioxoles; Brain; Cannabinoid Receptor Agonists; Cyclohexanols; Disease Models, Animal; Dronabinol; Endocannabinoids; Excitatory Postsynaptic Potentials; Glycerides; Heterocyclic Compounds, 1-Ring; Locomotion; Male; Mice; Mice, Inbred ICR; Piperidines; Polyunsaturated Alkamides; Pyridines; Signal Transduction | 2017 |
Spinal microglia are required for long-term maintenance of neuropathic pain.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cyclohexanols; Cytokines; Disease Models, Animal; Excitatory Postsynaptic Potentials; Male; Microglia; Neuralgia; Oximes; Rats; Rats, Sprague-Dawley; Receptor, trkB; Ribosome Inactivating Proteins, Type 1; RNA, Messenger; Saporins; Signal Transduction; Spinal Cord | 2017 |
Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models.
Topics: Animals; Antiparkinson Agents; Catalepsy; Cyclohexanols; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Oxotremorine; Parkinsonian Disorders; Reserpine | 2017 |
Sex differences in antinociceptive response to Δ-9-tetrahydrocannabinol and CP 55,940 in the mouse formalin test.
Topics: Analgesics; Analysis of Variance; Animals; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Female; Formaldehyde; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Pain; Pain Measurement; Receptor, Cannabinoid, CB1; Sex Characteristics; Time Factors; Treatment Outcome | 2018 |
Anti-inflammatory and anti-edematogenic action of the Croton campestris A. St.-Hil (Euphorbiaceae) essential oil and the compound β-caryophyllene in in vivo models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Croton; Cyclohexanols; Dextrans; Disease Models, Animal; Drug Evaluation, Preclinical; Edema; Eucalyptol; Inflammation; Male; Mice; Monoterpenes; Oils, Volatile; Plant Extracts; Plant Leaves; Polycyclic Sesquiterpenes; Sesquiterpenes; Toxicity Tests, Acute | 2018 |
Endocannabinoid and Muscarinic Signaling Crosstalk in the 3xTg-AD Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Brain; Cannabinoids; Cholinergic Agents; Cyclohexanols; Disease Models, Animal; Endocannabinoids; Gene Expression Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Oxazines; Presenilin-1; Radioisotopes; Signal Transduction; tau Proteins | 2018 |
β-lactams modulate astroglial glutamate transporters and attenuate dependence to CP 55,940, a CB1 receptor agonist, in rat model.
Topics: Amino Acid Transport System X-AG; Ampicillin; Animals; Astrocytes; beta-Lactams; Brain; Cannabinoid Receptor Agonists; Central Nervous System Agents; Cyclohexanols; Disease Models, Animal; Drug-Seeking Behavior; Gene Expression; Male; Rats; Receptor, Cannabinoid, CB1; Substance-Related Disorders; Sulbactam | 2019 |
In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling.
Topics: Animals; beta-Glucosidase; Brain; Cyclohexanols; Disease Models, Animal; Enzyme Assays; Glucosylceramidase; Glycoside Hydrolase Inhibitors; HEK293 Cells; Humans; Inositol; Isoenzymes; Kinetics; Larva; Lysosomes; Mice; Parkinson Disease; Zebrafish | 2019 |
Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish.
Topics: Animals; Cyclohexanols; Disease Models, Animal; Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Zebrafish; Zebrafish Proteins | 2019 |
The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells.
Topics: Animals; Antidepressive Agents, Second-Generation; Blotting, Western; Cell Death; Corticosterone; Cyclohexanols; Disease Models, Animal; Forkhead Box Protein O3; Forkhead Transcription Factors; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Venlafaxine Hydrochloride | 2013 |
Increased alcohol consumption in rats after subchronic antidepressant treatment.
Topics: Alcohol Drinking; Alcohols; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Addictive; Body Weight; Conditioning, Operant; Cyclohexanols; Disease Models, Animal; Fluoxetine; Male; Motor Activity; Rats; Rats, Wistar; Self Administration; Time Factors; Venlafaxine Hydrochloride | 2013 |
Further evaluation of the neuropharmacological determinants of the antidepressant-like effects of curcumin.
Topics: Animals; Antidepressive Agents; Brain; Curcumin; Cyclohexanols; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; Male; Mice; Mice, Knockout; Monoamine Oxidase Inhibitors; Protein Binding; Receptor, Cannabinoid, CB1; Receptors, Biogenic Amine; Swimming | 2013 |
Beneficial effects of fluoxetine, reboxetine, venlafaxine, and voluntary running exercise in stressed male rats with anxiety- and depression-like behaviors.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Cyclohexanols; Depression; Disease Models, Animal; Fluoxetine; Food Preferences; Male; Maze Learning; Morpholines; Physical Conditioning, Animal; Rats; Rats, Wistar; Reboxetine; Restraint, Physical; Running; Stress, Psychological; Sucrose; Swimming; Venlafaxine Hydrochloride | 2013 |
Methylphenidate and venlafaxine attenuate locomotion in spontaneously hypertensive rats, an animal model of attention-deficit/hyperactivity disorder, through α2-adrenoceptor activation.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Male; Methylphenidate; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors; Venlafaxine Hydrochloride | 2013 |
Desvenlafaxine succinate ameliorates visceral hypersensitivity but delays solid gastric emptying in rats.
Topics: Acetic Acid; Administration, Oral; Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Desvenlafaxine Succinate; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Gastric Emptying; Gastroparesis; Hyperalgesia; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mechanotransduction, Cellular; Norepinephrine; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Stomach; Stomach Ulcer | 2013 |
1,8-cineol attenuates LPS-induced acute pulmonary inflammation in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Eucalyptol; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred ICR; Monoterpenes; Peroxidase; Pneumonia; Pulmonary Edema; Toll-Like Receptor 4; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Development and evaluation of brain targeted intranasal alginate nanoparticles for treatment of depression.
Topics: Administration, Intranasal; Alginates; Animals; Antidepressive Agents; Brain; Cyclohexanols; Depression; Disease Models, Animal; Female; Glucuronic Acid; Hexuronic Acids; Male; Motor Activity; Nanoparticles; Nasal Mucosa; Pharmacokinetics; Rats; Rats, Wistar; Swimming; Time Factors; Venlafaxine Hydrochloride | 2014 |
Investigation of antihypertensive activity of carbopol valsartan transdermal gel containing 1,8-cineole.
Topics: Acrylic Resins; Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Chemistry, Pharmaceutical; Cyclohexanols; Disease Models, Animal; Eucalyptol; Gels; Monoterpenes; Rats; Skin; Tetrazoles; Valine; Valsartan | 2014 |
Analgesic effects of antidepressants alone and after their local co-administration with morphine in a rat model of neuropathic pain.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclohexanols; Disease Models, Animal; Doxepin; Hyperalgesia; Male; Morphine; Neuralgia; Pain Measurement; Pain Threshold; Rats; Sciatic Nerve; Venlafaxine Hydrochloride | 2014 |
Desvenlafaxine prevents white matter injury and improves the decreased phosphorylation of the rate-limiting enzyme of cholesterol synthesis in a chronic mouse model of depression.
Topics: Animals; Antidepressive Agents; Cholesterol; Cyclohexanols; Depression; Desvenlafaxine Succinate; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; Phosphorylation; Random Allocation; White Matter | 2014 |
Early increase of cannabinoid receptor density after experimental traumatic brain injury in the newborn piglet.
Topics: Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Brain; Brain Injuries; Cannabinoid Receptor Modulators; Cyclohexanols; Disease Models, Animal; Female; Isoquinolines; Piperidines; Protein Binding; Pyrazoles; Radionuclide Imaging; Receptors, Cannabinoid; Receptors, GABA; Rimonabant; Swine; Time Factors; Tritium | 2014 |
Venlafaxine inhibits apoptosis of hippocampal neurons by up-regulating brain-derived neurotrophic factor in a rat depression model.
Topics: Animals; Antidepressive Agents, Second-Generation; Apoptosis; Behavior, Animal; Blotting, Western; Brain-Derived Neurotrophic Factor; Cyclohexanols; Depression; Disease Models, Animal; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Male; Microscopy, Electron, Transmission; Neurons; Rats; Rats, Sprague-Dawley; Up-Regulation; Venlafaxine Hydrochloride | 2014 |
In vitro and in vivo characterization of PA01, a novel promising triple reuptake inhibitor.
Topics: Animals; Antidepressive Agents; Binding, Competitive; CHO Cells; Cricetulus; Cyclohexanols; Depression; Desvenlafaxine Succinate; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Humans; Hypothermia; Male; Mice; Molecular Structure; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats, Sprague-Dawley; Serotonin; Species Specificity | 2015 |
Assessment of in-utero venlafaxine induced, ROS-mediated, apoptotic neurodegeneration in fetal neocortex and neurobehavioral sequelae in rat offspring.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Apoptosis; bcl-2-Associated X Protein; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Exploratory Behavior; Female; Male; Microscopy, Electron; Neocortex; Nerve Degeneration; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Pyelectasis; Rats; Reactive Oxygen Species; Venlafaxine Hydrochloride | 2015 |
Desvenlafaxine reduces apoptosis in amygdala after myocardial infarction.
Topics: Amygdala; Analysis of Variance; Animals; Apoptosis; Caspase 3; Caspase 8; Cyclohexanols; Desvenlafaxine Succinate; Disease Models, Animal; In Situ Nick-End Labeling; Male; Myocardial Infarction; Neurotransmitter Uptake Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion; Statistics as Topic | 2014 |
Eucalyptol suppresses matrix metalloproteinase-9 expression through an extracellular signal-regulated kinase-dependent nuclear factor-kappa B pathway to exert anti-inflammatory effects in an acute lung inflammation model.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cyclohexanols; Cytokines; Dexamethasone; Disease Models, Animal; Drug Dosage Calculations; Eucalyptol; Extracellular Signal-Regulated MAP Kinases; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Monoterpenes; NF-kappa B; Nitric Oxide; Signal Transduction | 2015 |
CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain.
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Mice, Knockout; Neuralgia; Paclitaxel; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Treatment Outcome | 2015 |
Chronic cannabinoid exposure during adolescence leads to long-term structural and functional changes in the prefrontal cortex.
Topics: Animals; Blotting, Western; Cannabinoids; Chronic Disease; Cyclohexanols; Dendrites; Disease Models, Animal; Disks Large Homolog 4 Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Male; Marijuana Abuse; Membrane Proteins; Microelectrodes; Prefrontal Cortex; Pyramidal Cells; Rats, Wistar; Synaptophysin; Vesicular Glutamate Transport Proteins | 2016 |
Disruption of social cognition in the sub-chronic PCP rat model of schizophrenia: Possible involvement of the endocannabinoid system.
Topics: Analysis of Variance; Animals; Cannabinoid Receptor Modulators; Cyclohexanols; Discrimination, Psychological; Disease Models, Animal; Endocannabinoids; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Odorants; Phencyclidine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Schizophrenia; Schizophrenic Psychology; Social Behavior Disorders; Social Perception | 2016 |
Effect of JWH-250, JWH-073 and their interaction on "tetrad", sensorimotor, neurological and neurochemical responses in mice.
Topics: Animals; Anisoles; Brain; Cells, Cultured; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Feedback, Sensory; Gait Disorders, Neurologic; Humans; Hypothermia; Indoles; Male; Mice; Mice, Inbred ICR; Naphthalenes; Nervous System Diseases; Pain Threshold; Reflex, Acoustic; Spleen; Vision, Ocular | 2016 |
Quantification of pain in sickle mice using facial expressions and body measurements.
Topics: Analgesics; Anemia, Sickle Cell; Animals; Behavior, Animal; Cold Temperature; Cyclohexanols; Disease Models, Animal; Facial Expression; Female; Humans; Male; Mice; Mice, Transgenic; Pain; Pain Measurement; Posture; Reproducibility of Results; Research Design | 2016 |
Effects of cannabinoid receptor activation by CP55,940 on normal bladder function and irritation-induced bladder overactivity in non-awake anaesthetised rats.
Topics: Acetic Acid; Administration, Intravesical; Animals; Cannabinoid Receptor Agonists; Cyclohexanols; Disease Models, Animal; Female; Indoles; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Treatment Outcome; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics | 2016 |
Antidepressant-like Effects of LPM580153, A Novel Potent Triple Reuptake Inhibitor.
Topics: Anhedonia; Animals; Antidepressive Agents; Biological Transport; Blotting, Western; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cell Survival; Corticosterone; Cyclohexanols; Depression; Disease Models, Animal; Dopamine; Extracellular Signal-Regulated MAP Kinases; Humans; Male; Mice; Molecular Structure; Neuroblastoma; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phenethylamines; Rats, Sprague-Dawley; Serotonin; Weight Gain | 2016 |
Effect of 1.8-Cineole in Dermatophagoides pteronyssinus-Stimulated Bronchial Epithelial Cells and Mouse Model of Asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Line; Cell Survival; Cyclohexanols; Cytokines; Dermatophagoides pteronyssinus; Disease Models, Animal; Eosinophils; Epithelial Cells; Eucalyptol; Female; Humans; Lung; Mice, Inbred BALB C; Monoterpenes; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Respiratory Hypersensitivity; Respiratory Mucosa; Toll-Like Receptor 4 | 2016 |
Mentha longifolia protects against acetic-acid induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis; Colon; Cyclohexanols; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Eucalyptol; Gastrointestinal Agents; Glutathione; Interleukin-6; Male; Malondialdehyde; Mentha; Monoterpenes; Peroxidase; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Sulfasalazine; Time Factors; Tumor Necrosis Factor-alpha | 2016 |
Eucalyptol attenuates cigarette smoke-induced acute lung inflammation and oxidative stress in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Eucalyptol; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Monoterpenes; Neutrophils; Oxidative Stress; Peroxidase; Pneumonia; Reactive Oxygen Species; Smoke; Smoking; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
Antinociceptive and anticonvulsant effects of the monoterpene linalool oxide.
Topics: Acetic Acid; Acyclic Monoterpenes; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Formaldehyde; Lethal Dose 50; Male; Mice; Monoterpenes; Motor Activity; Nociception; Nociceptive Pain; Pentylenetetrazole; Reaction Time; Rotarod Performance Test; Seizures; Time Factors; Trityl Compounds | 2017 |
Isoflavin-β modifies muscle oxidative stress and prevents a thyrotoxicosis-induced loss of muscle mass in rats.
Topics: Animals; Antioxidants; Chymotrypsin; Cyclohexanols; Disease Models, Animal; Drug Administration Schedule; Electron Transport Complex IV; Glycerol; Isoflavones; Male; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Thyrotoxicosis | 2017 |
Genetic and pharmacological manipulations of the CB(1) receptor alter ethanol preference and dependence in ethanol preferring and nonpreferring mice.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Analgesics; Animals; Binding, Competitive; Brain; Cyclohexanols; Disease Models, Animal; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Rimonabant; Species Specificity | 2008 |
Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment.
Topics: Analgesics; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Cyclohexanols; Depressive Disorder, Major; Disease Models, Animal; Endocannabinoids; Imipramine; Male; Motivation; Polyunsaturated Alkamides; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Sexual Behavior, Animal; Stress, Psychological | 2008 |
Risperidone, an atypical antipsychotic enhances the antidepressant-like effect of venlafaxine or fluoxetine: possible involvement of alpha-2 adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanols; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Immobility Response, Tonic; Locomotion; Male; Mice; Receptors, Adrenergic, alpha-2; Risperidone; Swimming; Venlafaxine Hydrochloride; Yohimbine | 2008 |
Reduction in the latency of action of antidepressants by 17 beta-estradiol in the forced swimming test.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Cyclohexanols; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Estradiol; Estrogens; Female; Fluoxetine; Injections, Subcutaneous; Motor Activity; Ovariectomy; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Swimming; Venlafaxine Hydrochloride | 2008 |
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Macaca fascicularis; Male; Manganese; Parkinsonian Disorders; Positron-Emission Tomography; Substantia Nigra; Synaptic Transmission; Tetrabenazine; Tyrosine 3-Monooxygenase | 2008 |
Altered CB receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Autoradiography; Cyclohexanols; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Exploratory Behavior; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Immunosuppressive Agents; Isotopes; Male; Olfactory Bulb; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Signal Transduction; Time Factors | 2009 |
1,8-Cineole induces relaxation in rat and guinea-pig airway smooth muscle.
Topics: Animals; Bronchi; Bronchodilator Agents; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Eucalyptol; Female; Fenoterol; Guinea Pigs; Inhibitory Concentration 50; Male; Monoterpenes; Muscle Relaxation; Muscle, Smooth; Ovalbumin; Rats; Rats, Wistar; Trachea | 2009 |
Antinociceptive effects of the non-selective cannabinoid receptor agonist CP 55,940 are absent in CB1(-/-) and not CB2(-/-) mice in models of acute and persistent pain.
Topics: Analgesics; Animals; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Hot Temperature; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pain; Pain Measurement; Physical Stimulation; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Nerves | 2009 |
Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Arginine; Caffeine; Central Nervous System Stimulants; Chronic Disease; Cyclohexanols; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Random Allocation; Swimming; Venlafaxine Hydrochloride | 2010 |
Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant.
Topics: Amides; Analysis of Variance; Animals; Autoradiography; Benzoxazines; Body Weight; Brain; Cyclohexanols; Diet Fads; Disease Models, Animal; Eating; Female; Guanosine 5'-O-(3-Thiotriphosphate); International Cooperation; Morpholines; Naphthalenes; Obesity; Piperidines; Protein Binding; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Sulfur Isotopes; Time Factors; Tomography Scanners, X-Ray Computed; Tritium; Whole Body Imaging | 2010 |
Efficacy of tramadol in combination with doxepin or venlafaxine in inhibition of nociceptive process in the rat model of neuropathic pain: an isobolographic analysis.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Drug Therapy, Combination; Hyperalgesia; Male; Neuralgia; Pain Measurement; Rats; Rats, Wistar; Statistics as Topic; Tramadol; Venlafaxine Hydrochloride | 2009 |
Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; CA3 Region, Hippocampal; Cyclohexanols; Dentate Gyrus; Disease Models, Animal; Food Preferences; Hippocampus; Imipramine; In Situ Hybridization; Locomotion; Male; Maze Learning; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saccharin; Stress, Psychological; Sweetening Agents; Swimming; Time Factors; Venlafaxine Hydrochloride | 2010 |
Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids.
Topics: Anemia, Sickle Cell; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Agonists; Cannabinoids; Cyclohexanols; Disease Models, Animal; Female; Hemoglobin, Sickle; Humans; Hyperalgesia; Male; Mice; Mice, Knockout; Mice, Transgenic; Morphine; Neuroglia; Pain; Receptors, Opioid, mu; Recombinant Proteins; Skin; Spinal Cord; Substance P | 2010 |
Protective effect of desipramine, venlafaxine and trazodone against experimental animal model of transient global ischemia: possible involvement of NO-cGMP pathway.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Brain; Catalase; Cyclic GMP; Cyclohexanols; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Glutathione; Ischemic Attack, Transient; Lipid Peroxidation; Mice; Models, Biological; Nitric Oxide; Signal Transduction; Trazodone; Venlafaxine Hydrochloride | 2010 |
The effects of the synthetic cannabinoid receptor agonists, WIN55,212-2 and CP55,940, on salicylate-induced tinnitus in rats.
Topics: Animals; Behavior, Animal; Benzoxazines; Conditioning, Operant; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Morpholines; Naphthalenes; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Salicylic Acid; Tinnitus | 2010 |
The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Drug Tolerance; Exploratory Behavior; Genotype; Heterozygote; Male; Mice; Mice, Mutant Strains; Motor Activity; Neuregulin-1; Proto-Oncogene Proteins c-fos; Psychotropic Drugs; Reflex, Startle; Schizophrenia | 2011 |
The antidepressant action of imipramine and venlafaxine involves suppression of nitric oxide synthesis.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanols; Depression; Disease Models, Animal; Imipramine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nitric Oxide; Swimming; Venlafaxine Hydrochloride | 2011 |
Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats.
Topics: Animals; Autoradiography; Brain; Brain Ischemia; Cyclohexanols; Disease Models, Animal; Estradiol; Estrogens; Female; Functional Laterality; Gene Expression Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Infarction, Middle Cerebral Artery; Piperidines; Protein Binding; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sulfur Isotopes; Time Factors; Tritium | 2011 |
Therapeutic effects of inhaled 1,8-cineole on allergic airway inflammation.
Topics: Animals; Anti-Inflammatory Agents; Cyclohexanols; Disease Models, Animal; Eucalyptol; Guinea Pigs; Inflammation; Mice; Monoterpenes; Peroxidase; Reactive Oxygen Species | 2011 |
Evaluation of antidepressant activity of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a β-substituted phenylethylamine in mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Behavior, Animal; Biogenic Amines; Brain; Cyclohexanols; Depression; Disease Models, Animal; Hindlimb Suspension; Hypnotics and Sedatives; Isoquinolines; Male; Mice; Motor Activity; Neurotransmitter Agents; Pentobarbital; Reserpine; Sleep; Swimming; Venlafaxine Hydrochloride | 2011 |
Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson's disease.
Topics: Animals; Antioxidants; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dopamine; Dronabinol; Glutamic Acid; Lipopolysaccharides; Male; Mice; Motor Activity; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Substantia Nigra; Tyrosine 3-Monooxygenase | 2011 |
Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a model of traumatic brain injury.
Topics: Animals; Anisoles; Brain Injuries; Cannabinoid Receptor Modulators; Cyclohexanols; Disease Models, Animal; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Neurons; Receptor, Cannabinoid, CB2; Resorcinols | 2011 |
Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae).
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Bicyclic Monoterpenes; Brazil; Bridged Bicyclo Compounds; Cyclohexanols; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Epidermal Growth Factor; Ethanol; Eucalyptol; Gastric Mucosa; Hyptis; Male; Monoterpenes; Mucus; Oils, Volatile; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Stomach Ulcer | 2011 |
Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in animal models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Cyclohexanols; Disease Models, Animal; Dopamine Antagonists; Drug Synergism; Haloperidol; Levodopa; Mice; Mice, Inbred C57BL; Molecular Conformation; Motor Activity; Neurotoxins; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Neurotransmitter; Stereoisomerism | 2011 |
Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Area Under Curve; Body Weight; Cyclohexanols; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Edema; Enzyme-Linked Immunosorbent Assay; Freezing Reaction, Cataleptic; Hyperalgesia; Inflammation; Locomotion; Male; Mice; Neuralgia; Oleanolic Acid; Oligodeoxyribonucleotides, Antisense; Pain Threshold; Pentacyclic Triterpenes; Peroxidase; Protein Binding; Rats; Rats, Wistar; Receptors, Cannabinoid; Tritium | 2011 |
Metabonomic study on chronic unpredictable mild stress and intervention effects of Xiaoyaosan in rats using gas chromatography coupled with mass spectrometry.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biomarkers; Body Weight; Chronic Disease; Cyclohexanols; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Food Preferences; Gas Chromatography-Mass Spectrometry; Male; Metabolomics; Motor Activity; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stress, Psychological; Venlafaxine Hydrochloride | 2011 |
Discovery of potent, soluble and orally active TRPV1 antagonists. Structure-activity relationships of a series of isoxazoles.
Topics: Administration, Oral; Amides; Animals; Capsaicin; Cyclohexanols; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Isoxazoles; Microsomes, Liver; Rats; Structure-Activity Relationship; TRPV Cation Channels | 2011 |
Effects of venlafaxine and escitalopram treatments on NMDA receptors in the rat depression model.
Topics: Animals; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Depression; Disease Models, Animal; Hippocampus; Male; Random Allocation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Venlafaxine Hydrochloride | 2011 |
Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response.
Topics: Action Potentials; Animals; Antidepressive Agents, Second-Generation; Anxiety; Brain; Corticosterone; Cyclohexanols; Depression; Disease Models, Animal; Female; Hippocampus; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Imaging; Norepinephrine; Organic Cation Transport Proteins; Organic Cation Transporter 2; Radioligand Assay; Serotonin; Venlafaxine Hydrochloride | 2012 |
[Effect of venlafaxine on cognitive function and hippocampal brain-derived neurotrophic factor expression in rats with post-stroke depression].
Topics: Animals; Brain-Derived Neurotrophic Factor; Cyclohexanols; Depression; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memory; Memory Disorders; Rats; Rats, Sprague-Dawley; Stroke; Venlafaxine Hydrochloride | 2011 |
Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density.
Topics: Analysis of Variance; Animals; Autoradiography; Body Weight; Brain; Bulimia; Cannabinoids; Cyclohexanols; Diet; Disease Models, Animal; Eating; Female; Food Deprivation; Food Preferences; Gene Expression Regulation; Genes; Nodose Ganglion; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; RNA, Messenger; Tritium | 2012 |
Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness.
Topics: Age Factors; Analgesics; Anemia, Sickle Cell; Animals; Cannabinoid Receptor Antagonists; Cyclohexanols; Disease Models, Animal; Humans; Hyperalgesia; Hypoxia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Pain Measurement; Temperature | 2012 |
Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis.
Topics: Adult; Aged; Animals; Bleomycin; Cell Survival; Cells, Cultured; Cyclohexanols; Disease Models, Animal; Extracellular Matrix Proteins; Female; Fibrosis; Gene Targeting; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Middle Aged; Phosphorylation; Purines; Scleroderma, Systemic; Skin; Skin Diseases; Young Adult | 2012 |
Venlafaxine facilitates between-session extinction and prevents reinstatement of auditory-cue conditioned fear.
Topics: Acoustic Stimulation; Animals; Antidepressive Agents, Second-Generation; Anxiety Disorders; Conditioning, Psychological; Cues; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Fear; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Time Factors; Venlafaxine Hydrochloride | 2012 |
Antidepressant-like effect of the ethanolic extract from Suanzaorenhehuan Formula in mice models of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chemical Fractionation; Cyclohexanols; Depression; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Ethanol; Hippocampus; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase; Motor Activity; Norepinephrine; Phytotherapy; Plants, Medicinal; Prefrontal Cortex; Serotonin; Solvents; Time Factors; Venlafaxine Hydrochloride | 2012 |
Anti-depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: a plasma metabonomics study based on NMR spectroscopy.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biomarkers; Chronic Disease; Cyclohexanols; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Fluoxetine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Motor Activity; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Stress, Psychological; Sucrose; Venlafaxine Hydrochloride | 2012 |
Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions.
Topics: Animals; Anisoles; Blood-Brain Barrier; Camphanes; Cannabinoids; Capillary Permeability; Cell Adhesion; Cells, Cultured; Cyclohexanols; Dextrans; Disease Models, Animal; Electric Impedance; Encephalitis; Endothelial Cells; Endothelium; Flow Cytometry; Fluorescein-5-isothiocyanate; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Leukocytes; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins; Platelet Endothelial Cell Adhesion Molecule-1; Pyrazoles; Receptor, Cannabinoid, CB2; Statistics, Nonparametric; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Zonula Occludens-1 Protein | 2012 |
Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease.
Topics: Acetamides; Amines; Animals; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Diurnal Enuresis; Drug Discovery; Estradiol; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Hypnotics and Sedatives; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Skin Temperature; Venlafaxine Hydrochloride | 2012 |
Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factors.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Cyclohexanols; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Risk Factors; RNA, Messenger; Social Behavior; Stress, Psychological; Thiazepines; Venlafaxine Hydrochloride; Vesicular Glutamate Transport Protein 1 | 2012 |
Inhibition of calcineurin in the prefrontal cortex induced depressive-like behavior through mTOR signaling pathway.
Topics: Animals; Antidepressive Agents, Second-Generation; Calcineurin Inhibitors; Cyclohexanols; Cyclosporine; Depression; Disease Models, Animal; Immunosuppressive Agents; Male; Microinjections; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sucrose; Tacrolimus; TOR Serine-Threonine Kinases; Venlafaxine Hydrochloride | 2013 |
Upregulation of CB₁ receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure.
Topics: Adaptation, Psychological; Analgesics; Animals; Cues; Cyclohexanols; Disease Models, Animal; Male; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Stress, Psychological; Swimming; Tritium; Up-Regulation | 2013 |
3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol: the importance of functional groups for antiparkinsonian activity.
Topics: Animals; Antiparkinson Agents; Cyclohexanols; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Parkinson Disease | 2013 |
Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 2. Efficacy studies in allergic and pulmonary inflammation models in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclohexanols; Dermatitis, Allergic Contact; Disease Models, Animal; Enzyme Activators; Female; Indans; Inositol Polyphosphate 5-Phosphatases; Isoenzymes; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophil Infiltration; Passive Cutaneous Anaphylaxis; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Respiratory Mucosa; Respiratory Tract Diseases | 2013 |
Effects of early maternal separation on biobehavioral and neuropathological markers of Alzheimer's disease in adult male rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Aspartic Acid Endopeptidases; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line, Tumor; Cell Proliferation; Cognition Disorders; Cyclohexanols; Disease Models, Animal; Disks Large Homolog 4 Protein; Female; Gene Expression Regulation; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Male; Maternal Deprivation; Membrane Proteins; Mitogen-Activated Protein Kinase 8; Peptide Fragments; Pregnancy; Rats; Rats, Wistar; Recognition, Psychology; Synaptophysin; tau Proteins; Venlafaxine Hydrochloride | 2013 |
Biochemical mechanism studies of venlafaxine by metabonomic method in rat model of depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Biogenic Monoamines; Brain; Cyclohexanols; Depression; Disease Models, Animal; Male; Metabolomics; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Venlafaxine Hydrochloride | 2013 |
Antiparkinsonian activity of some 9-N-, O-, S- and C-derivatives of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol.
Topics: Animals; Antiparkinson Agents; Cyclohexanols; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Stereoisomerism | 2013 |
Effects on drug disposition, brain monoamines and behavior after chronic treatment with the antidepressant venlafaxine in rats with experimental hepatic encephalopathy.
Topics: Analysis of Variance; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Cyclohexanols; Dialysis Solutions; Disease Models, Animal; Enzyme Inhibitors; Hepatic Encephalopathy; Male; Microdialysis; Motor Activity; Rats; Rats, Sprague-Dawley; Venlafaxine Hydrochloride | 2002 |
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids, Neutral; Animals; Arachidonic Acids; Basal Ganglia; Cannabinoid Receptor Modulators; Capsaicin; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Endocannabinoids; gamma-Aminobutyric Acid; Huntington Disease; Hyperkinesis; Male; Motor Activity; Nitro Compounds; Palmitates; Piperidines; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Behavioural and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.
Topics: Animals; Autoradiography; Behavior, Animal; Benzoxazines; Binding, Competitive; Body Temperature; Brain; Cannabinoids; Corticosterone; Cyclohexanols; Disease Models, Animal; Drug Tolerance; Enkephalins; Exploratory Behavior; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Morpholines; Motor Activity; Naphthalenes; Pro-Opiomelanocortin; Protein Precursors; RNA, Messenger; Substance Withdrawal Syndrome; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2003 |
The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression.
Topics: Animals; Atropine Derivatives; Benzoxazines; Bradycardia; Cannabinoids; Cardiovascular System; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Hypotension; Male; Medulla Oblongata; Microinjections; Morpholines; Naphthalenes; Norepinephrine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System | 2003 |
Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism.
Topics: Amidohydrolases; Animals; Antiparkinson Agents; Arachidonic Acids; Binding, Competitive; Cannabinoid Receptor Modulators; Cerebellum; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Endocannabinoids; Excitatory Postsynaptic Potentials; Fatty Acids, Unsaturated; Glutamic Acid; Glycerides; In Vitro Techniques; Levodopa; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Phospholipase D; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug | 2003 |
Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats.
Topics: alpha-Methyltyrosine; Analgesics; Animals; Antidepressive Agents; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fenclonine; Male; Mononeuropathies; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Venlafaxine Hydrochloride; Vocalization, Animal | 2003 |
The antinociceptive effect of tramadol-venlafaxine combination on the paw withdrawal threshold in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Cyclohexanols; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Male; Pain Threshold; Pressure; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Tramadol; Venlafaxine Hydrochloride | 2003 |
Evidence for an antihyperalgesic effect of venlafaxine in vincristine-induced neuropathy in rat.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Antineoplastic Agents, Phytogenic; Cyclohexanols; Disease Models, Animal; Hyperalgesia; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride; Vincristine | 2003 |
1,8-cineole (eucalyptol), a monoterpene oxide attenuates the colonic damage in rats on acute TNBS-colitis.
Topics: Acute Disease; Administration, Rectal; Animals; Anti-Inflammatory Agents; Colitis; Colon; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Eucalyptol; Glutathione; Instillation, Drug; Intestinal Mucosa; Male; Monoterpenes; Organ Size; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2004 |
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
Topics: Amines; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Memantine; Pain; Pain Threshold; Pregabalin; Prodrugs; Rats; Sciatic Neuropathy; Structure-Activity Relationship; Venlafaxine Hydrochloride | 2004 |
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala.
Topics: Amygdala; Analgesics; Animals; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Genes, fos; Male; Mice; Mice, Inbred ICR; Restraint, Physical; Stress, Psychological | 2005 |
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Ataxia; Behavior, Animal; Benzoxazines; Binding, Competitive; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunosuppressive Agents; Indoles; Indomethacin; Inflammation; Male; Mice; Mice, Knockout; Morpholines; Naphthalenes; Pain; Pain Measurement; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB2; Time Factors | 2005 |
Antihyperalgesic properties of the cannabinoid CT-3 in chronic neuropathic and inflammatory pain states in the rat.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Catalepsy; Cell Line; Chromatography; Cricetinae; Cricetulus; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypothermia; Inflammation; Ligation; Male; Morpholines; Motor Activity; Naphthalenes; Pain; Pain Measurement; Pain Threshold; Radioligand Assay; Rats; Rats, Wistar; Rotarod Performance Test; Sciatic Neuropathy; Sulfur Isotopes; Time Factors; Tritium | 2005 |
(R)-sila-venlafaxine: a selective noradrenaline reuptake inhibitor for the treatment of emesis.
Topics: Animals; Antiemetics; Crystallography, X-Ray; Cyclohexanols; Disease Models, Animal; Drug Evaluation, Preclinical; Ferrets; Humans; In Vitro Techniques; Male; Models, Molecular; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT3 Receptor Antagonists; Stereoisomerism; Structure-Activity Relationship; Venlafaxine Hydrochloride; Vomiting | 2006 |
Evaluation of antinociceptive and anti-inflammatory effects of venlafaxine in the rat.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclohexanols; Disease Models, Animal; Edema; Female; Male; Mice; Mice, Inbred BALB C; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Venlafaxine Hydrochloride | 2005 |
Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress-induced decrease in cell proliferation and BDNF expression in rat hippocampus.
Topics: Animals; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Cell Proliferation; Chronic Disease; Cyclohexanols; Depressive Disorder; Dibenzothiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hippocampus; Neuronal Plasticity; Neurons; Quetiapine Fumarate; Rats; Restraint, Physical; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Stem Cells; Stress, Psychological; Venlafaxine Hydrochloride | 2006 |
Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cyclohexanols; Disease Models, Animal; Memory; Mice; Mice, Transgenic; Nootropic Agents; Phenotype; Plaque, Amyloid; Synapses | 2006 |
Venlafaxine modulates depression-induced oxidative stress in brain and medulla of rat.
Topics: Animals; Antidepressive Agents, Second-Generation; Antioxidants; Brain; Cerebral Cortex; Cyclohexanols; Depression; Disease Models, Animal; Housing, Animal; Lipid Peroxidation; Male; Medulla Oblongata; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Venlafaxine Hydrochloride; Water Deprivation | 2007 |
Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew.
Topics: Animals; Antiemetics; Benzoxazines; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Dronabinol; Gamma Rays; Locomotion; Morpholines; Naphthalenes; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Shrews; Vomiting | 2007 |
Co-carcinogenic effect of cyclohexanol on the development of preneoplastic lesions in a rat hepatocarcinogenesis model.
Topics: Alkylating Agents; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cyclohexanols; Diethylnitrosamine; Disease Models, Animal; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2007 |
Wide spectrum modulation by KP-544 in models relevant for neuronal survival.
Topics: Animals; Astrocytes; Cell Death; Cell Survival; Cerebellum; Cyclohexanols; Disease Models, Animal; Drug Synergism; Female; Male; Methylazoxymethanol Acetate; Nerve Growth Factor; Neurites; Neurons; Neuroprotective Agents; Neurotoxins; PC12 Cells; Pregnancy; Pyrimidines; Rats; Schizophrenia | 2007 |
Activation of cannabinoid-1 receptors disrupts sensory gating and neuronal oscillation: relevance to schizophrenia.
Topics: Acoustic Stimulation; Action Potentials; Animals; Biological Clocks; Brain; Cyclohexanols; Disease Models, Animal; Electroencephalography; Evoked Potentials, Auditory; Fourier Analysis; Gait Disorders, Neurologic; Male; Maximum Tolerated Dose; Neural Pathways; Neurons; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Wakefulness | 2008 |
The novel substituted pyrimidine, KP544, reduces motor deficits in the R6/2 transgenic mouse model of Huntington's disease.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Brain; Cyclohexanols; Disease Models, Animal; Exploratory Behavior; Female; Huntington Disease; Mice; Mice, Transgenic; Motor Activity; Motor Skills; Movement Disorders; Mutation; Pyrimidines; Reaction Time | 2007 |
Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.
Topics: Animals; Anti-Obesity Agents; Benzodioxoles; Body Weight; Crystallography, X-Ray; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Humans; Hypothermia; Ligands; Male; Mice; Microsomes; Models, Molecular; Molecular Structure; Obesity; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Structure-Activity Relationship | 2008 |
Venlafaxine reverses chronic fatigue-induced behavioral, biochemical and neurochemical alterations in mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anxiety; Behavior, Animal; Cyclohexanols; Disease Models, Animal; Dopamine; Fatigue Syndrome, Chronic; Glutathione; Lipid Peroxidation; Male; Maze Learning; Memory; Mice; Motor Activity; Norepinephrine; Oxidative Stress; Selective Serotonin Reuptake Inhibitors; Serotonin; Venlafaxine Hydrochloride | 2008 |
Accumulation of tissue glucosylsphingosine in Gaucher-like mouse induced by the glucosylceramidase inhibitor cyclophellitol.
Topics: Animals; Brain; Cells, Cultured; Cyclohexanols; Disease Models, Animal; Gaucher Disease; Glucosylceramidase; In Vitro Techniques; Liver; Mice; Psychosine; Spleen | 1993 |
Changes in the cannabinoid receptor binding, G protein coupling, and cyclic AMP cascade in the CNS of rats tolerant to and dependent on the synthetic cannabinoid compound CP55,940.
Topics: Animals; Behavior, Animal; Brain; Cannabinoids; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclohexanols; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Drug Tolerance; GTP-Binding Proteins; Hippocampus; Injections, Intraperitoneal; Male; Marijuana Abuse; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Signal Transduction | 2000 |
1,8-cineol, a food flavoring agent, prevents ethanol-induced gastric injury in rats.
Topics: Administration, Oral; Alcoholism; Animals; Antioxidants; Cyclohexanols; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Eucalyptol; Flavoring Agents; Gastric Juice; Gastritis; Male; Menthol; Monoterpenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Terpenes | 2001 |
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain.
Topics: Analgesics; Animals; Benzoxazines; Cannabinoids; Cyclohexanols; Disease Models, Animal; Dronabinol; Hyperalgesia; Morpholines; Naphthalenes; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sciatica | 2001 |
1,8-cineole protects against liver failure in an in-vivo murine model of endotoxemic shock.
Topics: Animals; Cyclohexanols; Disease Models, Animal; Eucalyptol; Galactosamine; Lipopolysaccharides; Liver Failure; Male; Menthol; Mice; Monoterpenes; Shock, Septic; Solvents; Terpenes; Transaminases; Tumor Necrosis Factor-alpha | 2001 |
Cannabinoids inhibit nitric oxide production in bone marrow derived feline macrophages.
Topics: Animals; Bone Marrow Cells; Camphanes; Cannabinoids; Cats; Cyclohexanols; Disease Models, Animal; Feline Acquired Immunodeficiency Syndrome; Histocytochemistry; Immunosuppressive Agents; Macrophages; Nitric Oxide; Phagocytosis; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation.
Topics: Analgesics; Animals; Cannabinoid Receptor Modulators; Cannabinoids; Cannabinol; Croton Oil; Cyclohexanols; Dermatologic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Motility; Inflammatory Bowel Diseases; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |
Caries inhibition efficacy of an antiplaque/antigingivitis dentifrice.
Topics: Analysis of Variance; Animals; Anti-Infective Agents, Local; Cariostatic Agents; Cyclohexanols; Dental Caries; Dental Plaque; Dentifrices; Diet, Cariogenic; Disease Models, Animal; Eucalyptol; Eucalyptus; Fluorides; Gingivitis; Menthol; Monoterpenes; Oils, Volatile; Pharmaceutical Vehicles; Phosphates; Placebos; Random Allocation; Rats; Rats, Sprague-Dawley; Salicylates; Silicon Dioxide; Single-Blind Method; Streptococcus sobrinus; Terpenes; Thymol | 2000 |
Disposition of venlafaxine enantiomers in rats with hepatic encephalopathy after chronic drug treatment.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Cyclohexanols; Disease Models, Animal; Hepatic Encephalopathy; Humans; Male; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Safety; Stereoisomerism; Venlafaxine Hydrochloride | 2002 |