cyclohexanecarboxylic acid has been researched along with Asthma in 2 studies
*Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aonuma, M; Chiba, J; Iigo, Y; Iimura, S; Machinaga, N; Muro, F; Nakayama, A; Setoguchi, M; Sugimoto, Y; Taira, T; Takashi, T; Takayama, G; Watanabe, T; Yokoyama, M; Yoneda, Y | 2 |
2 other study(ies) available for cyclohexanecarboxylic acid and Asthma
| Article | Year |
|---|---|
Identification of trans-4-[1-[[7-fluoro-2-(1-methyl-3-indolyl)-6-benzoxazolyl]acetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid as a potent, orally active VLA-4 antagonist.
Topics: Administration, Oral; Animals; Asthma; Bronchi; Bronchoalveolar Lavage; Cell Line; Cyclohexanecarboxylic Acids; Eosinophils; Female; Humans; Integrin alpha4beta1; Mice; Mice, Inbred BALB C; Structure-Activity Relationship | 2012 |
A novel, potent, and orally active VLA-4 antagonist with good aqueous solubility: trans-4-[1-[[2-(5-Fluoro-2-methylphenylamino)-7-fluoro-6-benzoxazolyl]acetyl]-(5S)-[methoxy(methyl)amino]methyl-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Asthma; Biological Availability; Bronchi; Cell Line; Cyclohexanecarboxylic Acids; Eosinophils; Female; Haplorhini; Humans; Integrin alpha4beta1; Mice; Mice, Inbred BALB C; Pyrrolidines; Solubility; Water | 2013 |