cycloguanil hydrochloride has been researched along with Malaria in 6 studies
*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davoll, J; Elslager, EF; Jacob, P; Johnson, AM; Johnson, J; Werbel, LM | 1 |
| Elslager, EF; Jacob, P; Johnson, J; Rane, L; Werbel, LM; Worth, DF | 1 |
| Elslager, EF; Hutt, MP; Jacob, P; Johnson, J; Rane, L; Temporelli, B; Werbel, LM; Worth, DF | 1 |
| Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
| Chen, W; Guan, L; Huang, J; Huang, Z; Jiang, H; Jiang, L; Li, J; Mao, F; Tang, Y; Wang, W; Zhu, J | 1 |
6 other study(ies) available for cycloguanil hydrochloride and Malaria
| Article | Year |
|---|---|
Folate antagonists. 12. Antimalarial and antibacterial effects of 2,4-diamino-6-[(aralkyl and alicyclid)thio-, sulfinyl-, and sulfonyl]quinazolines.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Enterococcus faecalis; Folic Acid Antagonists; Malaria; Mice; Microbial Sensitivity Tests; Plasmodium berghei; Quinazolines; Staphylococcus aureus | 1978 |
Folate antagonists. 13. 2,4-Diamino-6-](alpha,alpha,alpha-trifluoro-m-tolyl)thio]quinazoline and related 2,4-diamino-6-[(phenyl- and naphthyl)thio]quinazolines, a unique class of antimetabolites with extraordinary antimalarial and antibacterial effects.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Aotus trivirgatus; Bacteria; Chickens; Folic Acid Antagonists; Haplorhini; Malaria; Male; Mice; Microbial Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship | 1978 |
Folate antagonists. 15. 2,3-Diamino-6-(2-naphthylsulfonyl)quinazoline and related 2,4-diamino-6-[(phenyl and naphthyl)sulfinyl and sulfonyl]quinazolines, a potent new class of antimetabolites with phenomenal antimalarial activity.
Topics: Animals; Antimalarials; Bacteria; Chemical Phenomena; Chemistry; Chickens; Drug Resistance; Folic Acid Antagonists; Haplorhini; Malaria; Mice; Plasmodium; Quinazolines | 1979 |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2008 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |
Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely.
Topics: Animals; Antimalarials; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Folic Acid Antagonists; Malaria; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2017 |