cyclofenil has been researched along with Breast Neoplasms in 7 studies
Cyclofenil: A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbon-11 labeled cyclofenil derivatives, [(11)C]methyl-2-{4-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]16a), [(11)C]methyl-4-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]16b), [(11)C]methyl-2-{3-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]18a), and [(11)C]methyl-3-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]18b), have been synthesized as new potential PET agents for imaging breast cancer estrogen receptors." | 7.74 | Synthesis of new carbon-11 labeled cyclofenil derivatives for PET imaging of breast cancer estrogen receptors. ( Gao, M; Hutchins, GD; Miller, KD; Mock, BH; Sledge, GW; Wang, M; Zheng, QH, 2008) |
| "Carbon-11 labeled cyclofenil derivatives, [(11)C]methyl-2-{4-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]16a), [(11)C]methyl-4-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]16b), [(11)C]methyl-2-{3-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]18a), and [(11)C]methyl-3-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]18b), have been synthesized as new potential PET agents for imaging breast cancer estrogen receptors." | 3.74 | Synthesis of new carbon-11 labeled cyclofenil derivatives for PET imaging of breast cancer estrogen receptors. ( Gao, M; Hutchins, GD; Miller, KD; Mock, BH; Sledge, GW; Wang, M; Zheng, QH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, H | 1 |
| Huang, L | 1 |
| Zhang, Y | 1 |
| Xu, X | 1 |
| Sun, Y | 1 |
| Shen, YM | 1 |
| Kieser, KJ | 1 |
| Kim, DW | 2 |
| Carlson, KE | 2 |
| Katzenellenbogen, BS | 1 |
| Katzenellenbogen, JA | 2 |
| Seo, JW | 1 |
| Comninos, JS | 1 |
| Chi, DY | 1 |
| Gao, M | 1 |
| Wang, M | 1 |
| Mock, BH | 1 |
| Miller, KD | 1 |
| Sledge, GW | 1 |
| Hutchins, GD | 1 |
| Zheng, QH | 1 |
| Leclercq, G | 1 |
| Devleeschouwer, N | 1 |
| Heuson, JC | 1 |
| Lunan, CB | 1 |
| Klopper, A | 1 |
| Watts, CK | 1 |
| Sutherland, RL | 1 |
1 review available for cyclofenil and Breast Neoplasms
| Article | Year |
|---|---|
Antioestrogens. A review.
Topics: Animals; Breast Neoplasms; Chemical Phenomena; Chemistry; Clomiphene; Contraceptive Agents; Cyclofen | 1975 |
6 other studies available for cyclofenil and Breast Neoplasms
| Article | Year |
|---|---|
Design, synthesis, and evaluation of cyclofenil derivatives for potential SPECT imaging agents.
Topics: Breast Neoplasms; Cyclofenil; Drug Design; Drug Stability; Humans; Ligands; Octanols; Organotechneti | 2010 |
Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs).
Topics: Acrylates; Adaptor Proteins, Signal Transducing; Binding, Competitive; Breast Neoplasms; Bridged Bic | 2010 |
Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer.
Topics: Binding Sites; Binding, Competitive; Breast Neoplasms; Cyclofenil; Female; Fluorine; Humans; Ligands | 2006 |
Synthesis of new carbon-11 labeled cyclofenil derivatives for PET imaging of breast cancer estrogen receptors.
Topics: Breast Neoplasms; Carbon Radioisotopes; Cyclofenil; Female; Humans; Magnetic Resonance Spectroscopy; | 2008 |
In vitro testing of cytotoxic compounds in hormone-dependent and -independent breast cancer cell lines.
Topics: Breast Neoplasms; Cell Line; Cyclofenil; DNA; Drug Evaluation, Preclinical; Estrogen Antagonists; Es | 1984 |
Studies on the ligand specificity and potential identity of microsomal antiestrogen-binding sites.
Topics: Animals; Breast Neoplasms; Cell Line; Cyclofenil; Estrogen Antagonists; Humans; Microsomes; Nitromif | 1987 |