Page last updated: 2024-10-25

cyclobenzaprine and Transposition of Great Vessels

cyclobenzaprine has been researched along with Transposition of Great Vessels in 1 studies

cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.

Transposition of Great Vessels: A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.

Research Excerpts

ExcerptRelevanceReference
" Participants reported cyclobenzaprine use during the month before conception through the third month of pregnancy ("periconception") via computer-assisted telephone interview."8.31Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018). ( Ailes, EC; Browne, ML; Fisher, SC; Howley, MM; Nembhard, WN; Papadopoulos, EA; Tran, EL, 2023)
" Participants reported cyclobenzaprine use during the month before conception through the third month of pregnancy ("periconception") via computer-assisted telephone interview."4.31Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018). ( Ailes, EC; Browne, ML; Fisher, SC; Howley, MM; Nembhard, WN; Papadopoulos, EA; Tran, EL, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Fisher, SC1
Howley, MM1
Tran, EL1
Ailes, EC1
Papadopoulos, EA1
Nembhard, WN1
Browne, ML1

Other Studies

1 other study available for cyclobenzaprine and Transposition of Great Vessels

ArticleYear
Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018).
    Pharmacoepidemiology and drug safety, 2023, Volume: 32, Issue:8

    Topics: Case-Control Studies; Female; Humans; Infant; Logistic Models; Maternal Exposure; Pregnancy; Risk Fa

2023