cyclobenzaprine has been researched along with Pregnancy in 4 studies
cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Participants reported cyclobenzaprine use during the month before conception through the third month of pregnancy ("periconception") via computer-assisted telephone interview." | 8.31 | Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018). ( Ailes, EC; Browne, ML; Fisher, SC; Howley, MM; Nembhard, WN; Papadopoulos, EA; Tran, EL, 2023) |
| " Participants reported cyclobenzaprine use during the month before conception through the third month of pregnancy ("periconception") via computer-assisted telephone interview." | 4.31 | Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018). ( Ailes, EC; Browne, ML; Fisher, SC; Howley, MM; Nembhard, WN; Papadopoulos, EA; Tran, EL, 2023) |
| "Cyclobenzaprine is a skeletal muscle relaxant primarily used in the treatment of pain." | 3.91 | Transfer of Cyclobenzaprine into Human Milk and Subsequent Infant Exposure. ( Baker, T; Burra, B; Datta, P; Hale, TW; Rewers-Felkins, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, SC | 1 |
| Howley, MM | 1 |
| Tran, EL | 1 |
| Ailes, EC | 1 |
| Papadopoulos, EA | 1 |
| Nembhard, WN | 1 |
| Browne, ML | 1 |
| Burra, B | 1 |
| Datta, P | 1 |
| Rewers-Felkins, K | 1 |
| Baker, T | 1 |
| Hale, TW | 1 |
| Moreira, A | 1 |
| Barbin, C | 1 |
| Martinez, H | 1 |
| Aly, A | 1 |
| Fonseca, R | 1 |
| Hernández-Díaz, S | 1 |
| Su, YC | 1 |
| Mitchell, AA | 1 |
| Kelley, KE | 1 |
| Calafat, AM | 1 |
| Hauser, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.[NCT00011713] | 1,474 participants (Actual) | Observational | 1999-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for cyclobenzaprine and Pregnancy
| Article | Year |
|---|---|
Maternal cyclobenzaprine exposure and risk of birth defects in the National Birth Defects Prevention Study (1997-2011) and Birth Defects Study to Evaluate Pregnancy exposureS (2014-2018).
Topics: Case-Control Studies; Female; Humans; Infant; Logistic Models; Maternal Exposure; Pregnancy; Risk Fa | 2023 |
Transfer of Cyclobenzaprine into Human Milk and Subsequent Infant Exposure.
Topics: Adult; Amitriptyline; Breast Feeding; Diagnosis, Differential; Female; Humans; Infant, Newborn; Mass | 2019 |
Maternal use of cyclobenzaprine (Flexeril) may induce ductal closure and persistent pulmonary hypertension in neonates.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Antidepressive Agents, Tricyclic; Ductus Arteriosus; Fem | 2014 |
Medications as a potential source of exposure to phthalates among women of childbearing age.
Topics: Adolescent; Adult; Amitriptyline; Drug Utilization; Environmental Exposure; Female; Humans; Mesalami | 2013 |