cyclobenzaprine has been researched along with Neuroleptic Malignant Syndrome in 2 studies
cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Theoharides, TC | 1 |
| Harris, RS | 1 |
| Weckstein, D | 1 |
| Fink, M | 1 |
2 other studies available for cyclobenzaprine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant-like syndrome due to cyclobenzaprine?
Topics: Adult; Amitriptyline; Humans; Male; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome | 1995 |
Response to "Neuroleptic malignant-like syndrome due to cyclobenzaprine?".
Topics: Adult; Amitriptyline; Catatonia; Humans; Lead Poisoning; Male; Neuroleptic Malignant Syndrome; Tranq | 1996 |