cyclobenzaprine has been researched along with Muscle Spasticity in 4 studies
cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To quantify the risk of encephalopathy associated with oral baclofen compared with other muscle relaxants-tizanidine or cyclobenzaprine." | 1.91 | Baclofen and the Risk of Encephalopathy: A Real-World, Active-Comparator Cohort Study. ( Brotman, DJ; Chang, AR; Grams, ME; Hwang, YJ; Inker, LA; Shin, JI, 2023) |
| "Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder characterized by late-infantile onset spastic ataxia and other neurological features." | 1.37 | Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family. ( Abdala, N; Abdalla, C; Abrahão, A; Barsottini, OG; Braga-Neto, P; Pedroso, JL; Rivero, RL, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hwang, YJ | 1 |
| Chang, AR | 1 |
| Brotman, DJ | 1 |
| Inker, LA | 1 |
| Grams, ME | 1 |
| Shin, JI | 1 |
| Pedroso, JL | 1 |
| Braga-Neto, P | 1 |
| Abrahão, A | 1 |
| Rivero, RL | 1 |
| Abdalla, C | 1 |
| Abdala, N | 1 |
| Barsottini, OG | 1 |
| Brown, BR | 1 |
| Womble, J | 1 |
| Basmajian, JV | 1 |
2 trials available for cyclobenzaprine and Muscle Spasticity
| Article | Year |
|---|---|
Cyclobenzaprine in intractable pain syndromes with muscle spasm.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Diazepam; Dibenzocycloheptenes; Female; Humans; Male | 1978 |
Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: two double-blind controlled clinical and laboratory studies.
Topics: Administration, Oral; Amitriptyline; Computers; Dibenzocycloheptenes; Double-Blind Method; Drug Eval | 1978 |
2 other studies available for cyclobenzaprine and Muscle Spasticity
| Article | Year |
|---|---|
Baclofen and the Risk of Encephalopathy: A Real-World, Active-Comparator Cohort Study.
Topics: Adolescent; Adult; Baclofen; Brain Diseases; Cohort Studies; Humans; Muscle Relaxants, Central; Musc | 2023 |
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family.
Topics: Adult; Amitriptyline; Baclofen; Female; Humans; Magnetic Resonance Imaging; Male; Muscle Relaxants, | 2011 |