cyclobenzaprine has been researched along with Liver Diseases, Alcoholic in 1 studies
cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There was about a fourfold accumulation of the drug in plasma on multiple dosing, corresponding to an effective half-life of 18 hours." | 2.70 | Cyclobenzaprine pharmacokinetics, including the effects of age, gender, and hepatic insufficiency. ( Chavez-Eng, CM; Constanzer, ML; King, JD; Korn, SH; Winchell, GA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Winchell, GA | 1 |
| King, JD | 1 |
| Chavez-Eng, CM | 1 |
| Constanzer, ML | 1 |
| Korn, SH | 1 |
1 trial available for cyclobenzaprine and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Cyclobenzaprine pharmacokinetics, including the effects of age, gender, and hepatic insufficiency.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Analysis of Variance; Area Under Curv | 2002 |