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cyclobenzaprine and Drug Overdose

cyclobenzaprine has been researched along with Drug Overdose in 12 studies

cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"We present a case of a 15-year-old female who was admitted in a comatose state with no spontaneous respiratory effort and absence of brainstem reflexes after cyclobenzaprine ingestion."8.12Treatment of comatose patient from cyclobenzaprine overdose with therapeutic plasma exchange. ( Buyukgoz, C; Gangu, S; Gowani, F; Kimura, D, 2022)
"We present a case of a 15-year-old female who was admitted in a comatose state with no spontaneous respiratory effort and absence of brainstem reflexes after cyclobenzaprine ingestion."4.12Treatment of comatose patient from cyclobenzaprine overdose with therapeutic plasma exchange. ( Buyukgoz, C; Gangu, S; Gowani, F; Kimura, D, 2022)
"In this case report, a 22-year-old male developed severe hypothermia after an accidental overdose of cyclobenzaprine."3.81Use of an Intravascular Heat Exchange Catheter and Intravenous Lipid Emulsion for Hypothermic Cardiac Arrest After Cyclobenzaprine Overdose. ( Awad, NI; Bridgeman, PJ; Jeges, J; McCoy, JV; Page, E; Westrol, MS, 2015)
" Patients with an amitriptyline overdose were more likely to have seizure, coma, tachycardia, a wide QRS or ventricular dysrhythmia, and have received sodium bicarbonate or be intubated."3.77Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. ( Bebarta, VS; Borys, DJ; Maddry, J; Morgan, DL, 2011)
"Cyclobenzaprine has potential for sodium channel blockade and ventricular dysrhythmias although cardiac toxicity due to cyclobenzaprine alone is rare."1.42Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. ( Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Buyukgoz, C1
Gangu, S1
Gowani, F1
Kimura, D1
Bloom, J1
Hoffman, RS1
Kim, HS1
Ingalsbe, GS1
Lank, PM1
Perza, MN1
Schneider, LA1
Rosini, JM1
Chua-Tuan, JL1
Cao, D1
Iwanicki, JL1
Hoyte, CO1
Westrol, MS1
Awad, NI1
Bridgeman, PJ1
Page, E1
McCoy, JV1
Jeges, J1
Scanlon, KA1
Stoppacher, R1
Blum, LM1
Starkey, SJ1
Gillman, PK1
Menard-Katcher, C1
Henretig, FM1
Osterhoudt, KC1
Bebarta, VS2
Maddry, J2
Borys, DJ2
Morgan, DL2
Spiller, HA1
Cutino, L1

Other Studies

12 other studies available for cyclobenzaprine and Drug Overdose

ArticleYear
Treatment of comatose patient from cyclobenzaprine overdose with therapeutic plasma exchange.
    Journal of clinical apheresis, 2022, Volume: 37, Issue:3

    Topics: Adolescent; Amitriptyline; Coma; Drug Overdose; Female; Humans; Plasma Exchange; Plasmapheresis

2022
Comment on "Treatment of comatose patient from cyclobenzaprine overdose with therapeutic plasma exchange".
    Journal of clinical apheresis, 2022, Volume: 37, Issue:4

    Topics: Amitriptyline; Coma; Drug Overdose; Humans; Plasma Exchange; Plasmapheresis

2022
Unresponsive Male.
    Annals of emergency medicine, 2017, Volume: 69, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brugada Syndrome; Drug Overdose; Electrocardiograph

2017
Suspected tricyclic antidepressant overdose successfully treated with lipids.
    Journal of emergency nursing, 2013, Volume: 39, Issue:3

    Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Doxepin; Drug Overdose; Fat Em

2013
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6

    Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocar

2015
Use of an Intravascular Heat Exchange Catheter and Intravenous Lipid Emulsion for Hypothermic Cardiac Arrest After Cyclobenzaprine Overdose.
    Therapeutic hypothermia and temperature management, 2015, Volume: 5, Issue:3

    Topics: Amitriptyline; Cardiopulmonary Bypass; Cardiopulmonary Resuscitation; Drug Overdose; Fat Emulsions,

2015
Comprehensive Duloxetine Analysis in a Fatal Overdose.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:2

    Topics: Aged; Alcoholism; Amitriptyline; Depression; Diphenhydramine; Drug Overdose; Duloxetine Hydrochlorid

2016
Is there sufficient evidence to suggest cyclobenzaprine might be implicated in causing serotonin toxicity?
    The American journal of emergency medicine, 2009, Volume: 27, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Drug Overdose; Humans; Selective Serotonin Reuptake

2009
A 19-month-old girl with recurrent illness: over the hills and through the woods.
    Pediatric emergency care, 2009, Volume: 25, Issue:12

    Topics: Amitriptyline; Drug Overdose; Female; Humans; Infant; Lethargy; Muscle Relaxants, Central; Psychomot

2009
Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:6

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Chi-Square Distributio

2011
Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Drug Overdose; Humans; Incidence; Poison Control Ce

2012
Fatal cyclobenzaprine overdose with postmortem values.
    Journal of forensic sciences, 2003, Volume: 48, Issue:4

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Diazepam; Drug Overdose; Ethanol; Female; Humans; Ma

2003