cyclobenzaprine has been researched along with Back Ache in 8 studies
cyclobenzaprine: RN given refers to parent cpd; Lisseril is synonymous for HCl; structure
cyclobenzaprine : 5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This prospective, randomized, open-label, multicenter, community-based study was conducted to compare cyclobenzaprine 5 mg three times daily (TID) orally (CYC5) given for 7 days as monotherapy or in combination with ibuprofen 400 mg TID (CYC5/IBU400) or 800 mg TID (CYC5/IBU800) in adults with acute neck or back pain with muscle spasm." | 9.11 | Low-dose cyclobenzaprine versus combination therapy with ibuprofen for acute neck or back pain with muscle spasm: a randomized trial. ( Borenstein, D; Brown, RL; Childers, MK; Gershon, S; Hale, ME; Harrison, DD; Laudadio, C; Petri, M; Wan, GJ, 2005) |
| "Cyclobenzaprine hydrochloride is a muscle relaxant that is effective in improving muscle spasm, reducing local pain and tenderness, and increasing range of motion in acute, painful musculoskeletal conditions." | 9.10 | Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trials. ( Borenstein, DG; Korn, S, 2003) |
| "Back pain is a common problem for which cyclobenzaprine hydrochloride is frequently prescribed." | 8.81 | Cyclobenzaprine and back pain: a meta-analysis. ( Browning, R; Jackson, JL; O'Malley, PG, 2001) |
| " Along with other medications, cyclobenzaprine is a muscle relaxant commonly prescribed for patients complaining of musculoskeletal pain, in particular, pain associated with muscle spasms." | 8.31 | Cyclobenzaprine utilization for musculoskeletal back pain: Analysis of 2007-2019 National Hospital Ambulatory Medical Care Survey Data. ( AlRemeithi, R; Couperus, C; Martinez, S; Mazer-Amirshahi, M; Pourmand, A; Tran, QK; Yang, J, 2023) |
| "This prospective, randomized, open-label, multicenter, community-based study was conducted to compare cyclobenzaprine 5 mg three times daily (TID) orally (CYC5) given for 7 days as monotherapy or in combination with ibuprofen 400 mg TID (CYC5/IBU400) or 800 mg TID (CYC5/IBU800) in adults with acute neck or back pain with muscle spasm." | 5.11 | Low-dose cyclobenzaprine versus combination therapy with ibuprofen for acute neck or back pain with muscle spasm: a randomized trial. ( Borenstein, D; Brown, RL; Childers, MK; Gershon, S; Hale, ME; Harrison, DD; Laudadio, C; Petri, M; Wan, GJ, 2005) |
| "Cyclobenzaprine hydrochloride is a muscle relaxant that is effective in improving muscle spasm, reducing local pain and tenderness, and increasing range of motion in acute, painful musculoskeletal conditions." | 5.10 | Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trials. ( Borenstein, DG; Korn, S, 2003) |
| "Back pain is a common problem for which cyclobenzaprine hydrochloride is frequently prescribed." | 4.81 | Cyclobenzaprine and back pain: a meta-analysis. ( Browning, R; Jackson, JL; O'Malley, PG, 2001) |
| " Along with other medications, cyclobenzaprine is a muscle relaxant commonly prescribed for patients complaining of musculoskeletal pain, in particular, pain associated with muscle spasms." | 4.31 | Cyclobenzaprine utilization for musculoskeletal back pain: Analysis of 2007-2019 National Hospital Ambulatory Medical Care Survey Data. ( AlRemeithi, R; Couperus, C; Martinez, S; Mazer-Amirshahi, M; Pourmand, A; Tran, QK; Yang, J, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Pourmand, A | 1 |
| AlRemeithi, R | 1 |
| Martinez, S | 1 |
| Couperus, C | 1 |
| Mazer-Amirshahi, M | 1 |
| Yang, J | 1 |
| Tran, QK | 1 |
| Braschi, E | 1 |
| Garrison, S | 1 |
| Allan, GM | 1 |
| Borenstein, DG | 1 |
| Korn, S | 1 |
| Childers, MK | 1 |
| Borenstein, D | 1 |
| Brown, RL | 1 |
| Gershon, S | 1 |
| Hale, ME | 1 |
| Petri, M | 1 |
| Wan, GJ | 1 |
| Laudadio, C | 1 |
| Harrison, DD | 1 |
| Alim, M | 1 |
| Edelson, GW | 1 |
| Browning, R | 1 |
| Jackson, JL | 1 |
| O'Malley, PG | 1 |
| Basmajian, JV | 1 |
| Snapinn, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Flexeril� (Cyclobenzaprine Hydrochloride) Community Based Study - An Evaluation of Cyclobenzaprine HCl Monotherapy and in Combination With Ibuprofen for Acute Back or Neck Muscle Pain With Muscle Spasm[NCT00246389] | Phase 4 | 1,000 participants (Actual) | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for cyclobenzaprine and Back Ache
| Article | Year |
|---|---|
Cyclobenzaprine for acute back pain.
Topics: Acute Disease; Adult; Aged; Amitriptyline; Back Pain; Humans; Middle Aged; Muscle Relaxants, Central | 2015 |
Syncope in a young woman with chronic back pain.
Topics: Adult; Amitriptyline; Back Pain; Diagnosis, Differential; Emergency Medical Services; Female; Humans | 1993 |
Cyclobenzaprine and back pain: a meta-analysis.
Topics: Amitriptyline; Back Pain; Humans; Muscle Relaxants, Central; Randomized Controlled Trials as Topic | 2001 |
4 trials available for cyclobenzaprine and Back Ache
| Article | Year |
|---|---|
Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trials.
Topics: Acute Disease; Adult; Amitriptyline; Back Pain; Dose-Response Relationship, Drug; Double-Blind Metho | 2003 |
Low-dose cyclobenzaprine versus combination therapy with ibuprofen for acute neck or back pain with muscle spasm: a randomized trial.
Topics: Adolescent; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Dose-Response | 2005 |
Acute back pain and spasm. A controlled multicenter trial of combined analgesic and antispasm agents.
Topics: Acute Disease; Amitriptyline; Back Pain; Diflunisal; Double-Blind Method; Drug Therapy, Combination; | 1989 |
Evaluating the efficacy of a combination therapy.
Topics: Amitriptyline; Analgesics; Back Pain; Biometry; Clinical Trials as Topic; Diflunisal; Double-Blind M | 1987 |
1 other study available for cyclobenzaprine and Back Ache
| Article | Year |
|---|---|
Cyclobenzaprine utilization for musculoskeletal back pain: Analysis of 2007-2019 National Hospital Ambulatory Medical Care Survey Data.
Topics: Ambulatory Care; Back Pain; Emergency Service, Hospital; Female; Health Care Surveys; Hospitals; Hum | 2023 |