Page last updated: 2024-09-04

cycloastragenol and Disease Models, Animal

cycloastragenol has been researched along with Disease Models, Animal in 8 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Cao, Y; Chen, M; Dong, J; Li, C; Qin, J; Su, M; Tang, W; Teng, F; Tulake, W; Wang, S; Zhong, Y; Zhu, X1
Ahmad, S; Choe, K; Ikram, M; Jo, MH; Khan, A; Kim, MO; Kim, MW; Saeed, K1
Chen, M; Dong, J; Huang, X; Li, C; Liu, B; Ruan, Z; Shi, H; Sun, J; Wei, Y; Xu, W; Yu, H; Zhou, Y; Zhu, H; Zhu, X1
Du, M; Hu, W; Li, J; Li, L; Liu, Y; Luo, S; Wu, J; Yang, Y; Yao, W; Yu, Y; Zheng, X; Zhou, L1
Qi, R; Tuerdi, N; Wan, Y; Wang, Y; Xu, L; Ye, M1
Cai, H; Cao, SP; Song, YH; Wang, J; Wu, ML; Zhao, ZM1
Chen, W; Deng, G; Gu, Z; Ji, X; Sun, Y; Wang, P; Wang, X; Zhan, T; Zheng, W1
Ahuja, SS; Allsopp, R; Brampton, C; Davy, P; Fauce, S; Harley, CB; Le Saux, CJ; Nguyen, H; Pirot, Z; Ramaseshan, M; Shivshankar, P; Tressler, R1

Other Studies

8 other study(ies) available for cycloastragenol and Disease Models, Animal

ArticleYear
Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy.
    Molecular medicine reports, 2021, Volume: 24, Issue:5

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Autophagy; Autophagy-Related Proteins; Biomarkers; Biopsy; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Management; Disease Models, Animal; Disease Susceptibility; Drugs, Chinese Herbal; Female; Immunoglobulin E; Immunohistochemistry; Inflammation Mediators; Mice; Microtubule-Associated Proteins; Sapogenins; Structure-Activity Relationship

2021
Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions.
    Cells, 2021, 10-11, Volume: 10, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Astrocytes; Brain; Cyclic AMP Response Element-Binding Protein; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Inflammation; Inflammation Mediators; Memory Disorders; Mice, Inbred C57BL; Microglia; Nerve Growth Factors; Nerve Tissue Proteins; Neurodegenerative Diseases; Oxidative Stress; Phosphorylation; Sapogenins; Saponins; Triterpenes

2021
TMT-Based Quantitative Proteomic Analysis Reveals Downregulation of ITGAL and Syk by the Effects of Cycloastragenol in OVA-Induced Asthmatic Mice.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Down-Regulation; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Proteomics

2022
Cycloastragenol prevents age-related bone loss: Evidence in d-galactose-treated and aged rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: 3T3 Cells; Age Factors; Animals; Bone Density Conservation Agents; Bone Remodeling; Disease Models, Animal; Female; Femur; Galactose; Male; Membrane Glycoproteins; Mice; Osteoclasts; Osteogenesis; Osteoporosis; Rats, Sprague-Dawley; Sapogenins; Up-Regulation

2020
Preventive effects of astragaloside IV and its active sapogenin cycloastragenol on cardiac fibrosis of mice by inhibiting the NLRP3 inflammasome.
    European journal of pharmacology, 2018, Aug-15, Volume: 833

    Topics: Animals; Cardiovascular Diseases; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Fibroblasts; Fibrosis; Heart; Humans; Inflammasomes; Isoproterenol; Male; Mice; Mice, Inbred BALB C; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Triterpenes

2018
Cycloastragenol ameliorates experimental heart damage in rats by promoting myocardial autophagy via inhibition of AKT1-RPS6KB1 signaling.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Animals; Astragalus propinquus; Autophagy; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drugs, Chinese Herbal; Heart Failure; Isoproterenol; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Sapogenins; Signal Transduction

2018
Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin inflammation in mice.
    International immunopharmacology, 2019, Volume: 74

    Topics: Animals; Astragalus propinquus; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Humans; Imiquimod; Inflammasomes; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Psoriasis; Pyroptosis; Sapogenins; Skin

2019
A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Alveolar Epithelial Cells; Animals; Bleomycin; Cellular Senescence; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activators; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Inflammation; Lung; Mice; Respiratory Mucosa; Sapogenins; Telomerase

2013