cyclin-d1 and Splenic-Rupture

cyclin-d1 has been researched along with Splenic-Rupture* in 1 studies

Other Studies

1 other study(ies) available for cyclin-d1 and Splenic-Rupture

Article	Year
CD5 negative, Cyclin D1-positive diffuse large B-cell lymphoma (DLBCL) presenting as ruptured spleen. Applied immunohistochemistry & molecular morphology : AIMM, 2009, Volume: 17, Issue:3 We present a case of diffuse large B-cell lymphoma CD5 negative, Cyclin D1 positive presenting as ruptured spleen in a 63-year-old man requiring emergent splenectomy. Tumor cells showed marked pleomorphism, anaplasia, and increased mitotic figures with positive Cyclin D1, BCL6, MUM1, P53, and a high MIB1 proliferative fraction. The patient received multiple therapies and ultimately died. This case raises the differential diagnoses of pleomorphic mantle cell lymphoma and other aggressive lymphomas with pleomorphic, anaplastic, and Reed-Sternberg-like cells. Topics: Antineoplastic Combined Chemotherapy Protocols; CD5 Antigens; Cyclin D1; Diagnosis, Differential; Fatal Outcome; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Rupture, Spontaneous; Splenic Rupture; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases	2009

Article

Year

CD5 negative, Cyclin D1-positive diffuse large B-cell lymphoma (DLBCL) presenting as ruptured spleen.

Applied immunohistochemistry & molecular morphology : AIMM, 2009, Volume: 17, Issue:3

We present a case of diffuse large B-cell lymphoma CD5 negative, Cyclin D1 positive presenting as ruptured spleen in a 63-year-old man requiring emergent splenectomy. Tumor cells showed marked pleomorphism, anaplasia, and increased mitotic figures with positive Cyclin D1, BCL6, MUM1, P53, and a high MIB1 proliferative fraction. The patient received multiple therapies and ultimately died. This case raises the differential diagnoses of pleomorphic mantle cell lymphoma and other aggressive lymphomas with pleomorphic, anaplastic, and Reed-Sternberg-like cells.

Topics: Antineoplastic Combined Chemotherapy Protocols; CD5 Antigens; Cyclin D1; Diagnosis, Differential; Fatal Outcome; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Rupture, Spontaneous; Splenic Rupture; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases

2009