cyclin-d1 has been researched along with Leukemic-Infiltration* in 2 studies
2 other study(ies) available for cyclin-d1 and Leukemic-Infiltration
Article | Year |
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Swollen nail folds due to leukemic cell infiltration in a case of chronic lymphocytic leukemia.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, CD20; Biopsy; CD79 Antigens; Cyclin D1; Female; Fingers; Humans; Japan; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemic Infiltration; Lymphocytes; Receptors, Antigen, B-Cell; Receptors, IgE | 2004 |
Insertion of the CCND1 gene into the IgH locus in a case of leukaemic small cell mantle lymphoma with normal chromosomes 11 and 14.
The t(11;14)(q13;q32) translocation is considered to be the cytogenetic hallmark of mantle cell lymphoma. This report describes a case of leukaemic mantle cell lymphoma in which conventional cytogenetics on stimulated peripheral blood cells showed a 46,XY, t(1;12)(p21;q23)/46,XY karyotype. Fluorescence in situ hybridisation analysis using a dual colour immunoglobulin heavy chain (IgH)/CCND1 probe showed a fusion hybridisation signal on one normal chromosome 14, indicating that an insertion of the CCND1 gene into the 14q32/IgH locus had taken place. Overexpression of the cyclin D1 protein was demonstrated on bone marrow trephine by immunohistochemical staining. Topics: Biomarkers, Tumor; Bone Marrow Cells; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 12; Cyclin D1; Cytogenetic Analysis; Humans; Immunoglobulin Heavy Chains; Immunohistochemistry; In Situ Hybridization, Fluorescence; Leukemic Infiltration; Lymphoma, Mantle-Cell; Male; Middle Aged; Mutagenesis, Insertional | 2003 |