cyclin-d1 has been researched along with Biliary-Atresia* in 1 studies
1 other study(ies) available for cyclin-d1 and Biliary-Atresia
| Article | Year |
|---|---|
Immortalization of human hepatocytes from biliary atresia with CDK4
Hepatocytes are an important tool for in vitro toxicology testing. In addition to primary cultures, a limited number of immortalized cell lines have been developed. We here describe a new cell line, designated as HepaMN, which has been established from a liver associated with biliary atresia. Hepatocytes were isolated from a liver of 4-year-old girl with biliary atresia and immortalized by inoculation with CSII-CMV-TERT, CSII-CMV-Tet-Off, CSII-TRE-Tight-cyclin D1 and CSII-TRE-Tight-CDK4 Topics: Biliary Atresia; Cell Culture Techniques; Cell Line; Child, Preschool; Cost-Benefit Analysis; Cyclin D1; Cyclin-Dependent Kinase 4; Cytochrome P-450 CYP3A; Hepatocytes; Humans; Kinetics; Liver; Liver, Artificial; Phenotype; Principal Component Analysis; Regenerative Medicine; Rifampin; Telomerase | 2020 |