cyclic-gmp has been researched along with Antiphospholipid-Syndrome* in 1 studies
1 other study(ies) available for cyclic-gmp and Antiphospholipid-Syndrome
| Article | Year |
|---|---|
Adenosine diphosphate-induced aggregation is enhanced in platelets obtained from patients with thrombotic primary antiphospholipid syndrome (t-PAPS): Role of P2Y
Thrombotic antiphospholipid syndrome (t-PAPS) is characterized by arterial, venous, or microvascular occlusions, which are explained, in part, by the presence of antiphospholipid (aPL) antibodies. Although there is much evidence indicating that isolated aPL antibodies increase the activity of platelets obtained from healthy volunteers, platelet function in t-PAPS has not been as widely studied.. To evaluate platelet reactivity in t-PAPS patients.. Platelet aggregation, protein expression, and cyclic nucleotide levels were carried out in platelet rich plasma (PRP) or washed platelets (WPs) obtained from t-PAPS or healthy volunteers.. ADP-induced aggregation was significantly higher in PRP obtained from t-PAPS than obtained from the control. The protein expression of P2Y. The overexpression of P2Y Topics: Adenosine Diphosphate; Antiphospholipid Syndrome; Blood Platelets; Cyclic AMP; Cyclic GMP; Humans; Iloprost; Nitroprusside; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction | 2022 |