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cyclazocine and Drug Withdrawal Symptoms

cyclazocine has been researched along with Drug Withdrawal Symptoms in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199035 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aceto, MD1
Schuster, CR; Woolverton, WL1
Katz, JL; Valentino, RJ1
Aston-Jones, G; Valentino, RJ1
Isaacson, RL; Lanthorn, TH1
Jasinski, DR1
Smith, CB; Valentino, RJ; Woods, JH2
Tepper, P; Woods, JH1
Wikler, A1
Greenstein, R; O'Brien, CP; Ternes, J; Testa, T1
Fennessy, MR; Laska, FJ1
Gilbert, PE; Martin, WR1
Halbach, H1
Holtzman, SG; O'Callaghan, JP1
Chahl, LA1
Khazan, N; Young, GA1
Dykstra, LA; Gmerek, DE; Woods, JH1
Collins, RJ; Tang, AH1
Freed, EH; Freed, ME; Gluckman, MI; Malis, JL; Potoski, JR1
Cowan, A1
Karbowski, MG; Villarreal, JE1
Hayashi, G; Maruyama, Y; Smits, SE; Takemori, AE1
Chamblin, M; Drew, WG; Miller, LL1
Bläsig, J; Herz, A1
Gorodetzky, CW1
Fraser, HF1
McMillan, DE1
Haertzen, CA1
Renault, PF; Schuster, CR1
Goode, PG1
Fraser, HF; Gorodetzky, CW; Martin, WR; Rosenberg, DE1
Fink, M; Freedman, AM; Resnick, R; Zaks, A1
Fink, M; Freedman, AM; Resnick, RB; Zaks, A1
Gorodetzky, CW; Mulé, SJ1

Reviews

6 review(s) available for cyclazocine and Drug Withdrawal Symptoms

ArticleYear
Behavioral and pharmacological aspects of opioid dependence: mixed agonist-antagonists.
    Pharmacological reviews, 1983, Volume: 35, Issue:1

    Topics: Animals; Benzomorphans; Cyclazocine; Discrimination Learning; Disease Models, Animal; Humans; Morphine; Narcotic Antagonists; Opioid-Related Disorders; Pentazocine; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome

1983
Methadone maintenance and narcotic blocking drugs. Appendix.
    The International journal of the addictions, 1977, Volume: 12, Issue:7

    Topics: Administration, Oral; Cyclazocine; Drug Tolerance; Heroin Dependence; Humans; Injections, Subcutaneous; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Research; Substance Withdrawal Syndrome

1977
The actions of narcotic antagonists in morphine-dependent rhesus monkeys.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Animals; Behavior, Animal; Cyclazocine; Cyclopropanes; Dose-Response Relationship, Drug; Facial Expression; Handling, Psychological; Haplorhini; Humans; Morphinans; Morphine Dependence; Nalorphine; Naloxone; Narcotic Antagonists; Species Specificity; Structure-Activity Relationship; Substance Withdrawal Syndrome; Thebaine; Time Factors

1973
Assays of antagonistic activity of narcotic antagonists in man.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Analysis of Variance; Cyclazocine; Drug Evaluation; Humans; Morphine; Morphine Dependence; Nalorphine; Naloxone; Narcotic Antagonists; Pupil; Substance Withdrawal Syndrome; Surveys and Questionnaires; Time Factors

1973
Certain theoretical and practical considerations involved in evaluating the overall abuse potential of opiate agonists and antagonists.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Animals; Chlorpromazine; Codeine; Cyclazocine; Drug Combinations; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Lysergic Acid Diethylamide; Mice; Morphinans; Morphine; Morphine Dependence; Nalorphine; Naloxone; Narcotic Antagonists; Pentobarbital; Rats; Receptors, Drug; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders; Surveys and Questionnaires

1973
Effects of narcotics and narcotic antagonists on operant behavior.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Columbidae; Conditioning, Operant; Cyclazocine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Tolerance; Humans; Methadone; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Narcotics; Pentazocine; Rats; Reinforcement Schedule; Substance Withdrawal Syndrome

1973

Trials

3 trial(s) available for cyclazocine and Drug Withdrawal Symptoms

ArticleYear
Studies on the relationship between 5-hydroxytryptamine turnover in brain and tolerance and physical dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:1

    Topics: Animals; Aspirin; Brain; Cyclazocine; Drug Tolerance; Fenclonine; Humans; Levorphanol; Male; Methadone; Mice; Morphinans; Morphine; Morphine Dependence; Nalorphine; Pargyline; Pentazocine; Phenylalanine; Physostigmine; Placebos; Serotonin; Substance Withdrawal Syndrome

1971
Subjective effects of narcotic antagonists.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Analysis of Variance; Codeine; Cyclazocine; Dextropropoxyphene; Dose-Response Relationship, Drug; Emotions; Humans; Levallorphan; Lysergic Acid Diethylamide; Morphine Dependence; Nalbuphine; Nalorphine; Narcotic Antagonists; Pentazocine; Placebos; Substance Withdrawal Syndrome; Surveys and Questionnaires

1973
Studies of the dependence-producing potential of the narcotic antagonist 2-cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (cyclazocine, WIN-20,740, ARC II-c-3).
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 150, Issue:3

    Topics: Amphetamine; Analgesics; Barbiturates; Cannabis; Clinical Trials as Topic; Cocaine; Cyclazocine; Drug Tolerance; Euphoria; Humans; Morphine; Nalorphine; Narcotic Antagonists; Pupil; Substance Withdrawal Syndrome; Substance-Related Disorders

1965

Other Studies

26 other study(ies) available for cyclazocine and Drug Withdrawal Symptoms

ArticleYear
Characterization of prototypical opioid antagonists, agonist-antagonists, and agonists in the morphine-dependent rhesus monkey.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Buprenorphine; Cyclazocine; Ethylketocyclazocine; Humans; Macaca mulatta; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Receptors, Opioid, mu; Substance Withdrawal Syndrome

1984
The opiate quasiwithdrawal syndrome in rhesus monkeys: comparison of naloxone-precipitated withdrawal to effects of cholinergic agents.
    Psychopharmacology, 1984, Volume: 84, Issue:1

    Topics: Animals; Behavior, Animal; Cyclazocine; Female; Humans; Macaca mulatta; Male; Morphine Dependence; Naloxone; Parasympathomimetics; Physostigmine; Substance Withdrawal Syndrome

1984
Activation of locus coeruleus neurons in the rat by a benzazocine derivative (UM 1046) that mimics opiate withdrawal.
    Neuropharmacology, 1983, Volume: 22, Issue:12A

    Topics: Acetylcholine; Animals; Behavior, Animal; Cyclazocine; Dose-Response Relationship, Drug; Humans; Locus Coeruleus; Male; Neurons; Opioid-Related Disorders; Rats; Rats, Inbred Strains; Scopolamine; Substance Withdrawal Syndrome

1983
Hippocampal involvement in the pharmacologic induction of withdrawal-like behaviors.
    Federation proceedings, 1981, Volume: 40, Issue:5

    Topics: Animals; Cyclazocine; Endorphins; Enkephalin, Methionine; Enkephalins; Escape Reaction; Ethylketocyclazocine; Hippocampus; Humans; Injections, Intraventricular; Kainic Acid; Morphine Dependence; Pyrrolidines; Rats; Serotonin; Shivering; Substance Withdrawal Syndrome; Valproic Acid

1981
Stimulus control and drug dependence.
    NIDA research monograph, 1981, Volume: 37

    Topics: Behavior; Cyclazocine; Euphoria; Humans; Internal-External Control; Psychotropic Drugs; Substance Withdrawal Syndrome; Substance-Related Disorders

1981
Physiological and behavioral approaches to the study of the quasi-morphine withdrawal syndrome.
    Federation proceedings, 1981, Volume: 40, Issue:5

    Topics: Acetylcholine; Animals; Columbidae; Cyclazocine; Discrimination Learning; Guinea Pigs; Humans; Ileum; Macaca mulatta; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Parasympathomimetics; Substance Withdrawal Syndrome

1981
Changes in locomotor activity and naloxone-induced jumping in mice produced by WIN 35, 197-2 (ethylketazocine) and morphine.
    Psychopharmacology, 1978, Jul-06, Volume: 58, Issue:2

    Topics: Animals; Cocaine; Cyclazocine; Female; Humans; Mice; Morphine; Motor Activity; Naloxone; Narcotics; Substance Withdrawal Syndrome; Time Factors

1978
An unusual benzazocine elicits acetylcholine release in the isolated guinea pig ileum.
    Nature, 1979, Oct-04, Volume: 281, Issue:5730

    Topics: Acetylcholine; Animals; Cyclazocine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Naloxone; Receptors, Opioid; Substance Withdrawal Syndrome

1979
Conditioning effects of narcotics in humans.
    NIDA research monograph, 1978, Issue:18

    Topics: Conditioning, Psychological; Cyclazocine; Drug Tolerance; Humans; Naltrexone; Narcotics; Substance Withdrawal Syndrome

1978
Induction of physical dependence on cyclazocine and pentazocine in the rat.
    European journal of pharmacology, 1978, Mar-01, Volume: 48, Issue:1

    Topics: Animals; Behavior, Animal; Biogenic Amines; Body Temperature; Body Weight; Brain Chemistry; Cyclazocine; Female; Humans; Morphine; Pentazocine; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1978
The effects of morphine and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:1

    Topics: Animals; Behavior, Animal; Cyclazocine; Dogs; Drug Interactions; Female; Humans; Morphine; Morphine Dependence; Nalorphine; Spinal Cord; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1976
Pharmacological approaches to the treatment of morphine-type dependence.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Cyclazocine; Drug Therapy, Combination; Drug Tolerance; Humans; Methadone; Morphine Dependence; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome

1975
Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:3

    Topics: Analgesia; Analysis of Variance; Animals; Cyclazocine; Dose-Response Relationship, Drug; Drug Tolerance; Hot Temperature; Humans; Levallorphan; Male; Methods; Morphine; Naloxone; Narcotic Antagonists; Pentazocine; Rats; Reaction Time; Substance Withdrawal Syndrome

1975
Withdrawal responses of guinea-pig isolated ileum following brief exposure to opiates and opioid peptides.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:4

    Topics: Animals; Benzomorphans; Buprenorphine; Cyclazocine; Endorphins; Ethylketocyclazocine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Narcotics; Substance P; Substance Withdrawal Syndrome

1986
Comparison of abstinence syndromes following chronic administration of mu and kappa opioid agonists in the rat.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:3

    Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Ethylketocyclazocine; Female; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sleep, REM; Substance Withdrawal Syndrome

1985
Kappa opioids in rhesus monkeys. III. Dependence associated with chronic administration.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Cyclazocine; Drug Tolerance; Endorphins; Ethylketocyclazocine; Macaca mulatta; Morphinans; Morphine; Narcotic Antagonists; Pentobarbital; Pyrrolidines; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1987
Behavioral effects of a novel kappa opioid analgesic, U-50488, in rats and rhesus monkeys.
    Psychopharmacology, 1985, Volume: 85, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Cyclazocine; Discrimination, Psychological; Diuresis; Ethylketocyclazocine; Humans; Macaca mulatta; Male; Morphine; Naloxone; Pyrrolidines; Rats; Rats, Inbred Strains; Self Administration; Species Specificity; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1985
Bridged amino tetralins.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Analgesics; Animals; Bridged-Ring Compounds; Cyclazocine; Dose-Response Relationship, Drug; Electroshock; Haplorhini; Humans; Macaca; Mice; Morphine; Morphine Dependence; Nalorphine; Naloxone; Naphthalenes; Narcotic Antagonists; Pentazocine; Postural Balance; Rats; Reaction Time; Reflex; Substance Withdrawal Syndrome; Tail

1973
Evaluation in nonhuman primates: evaluation of the physical dependence capacities of oripavine-thebaine partial agonists in patas monkeys.
    Advances in biochemical psychopharmacology, 1973, Volume: 8, Issue:0

    Topics: Analgesics; Animals; Cyclazocine; Female; Haplorhini; Humans; Male; Mice; Morphinans; Morphine; Morphine Dependence; Nalorphine; Naloxone; Narcotic Antagonists; Pentazocine; Stereotyped Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders; Thebaine; Time Factors

1973
Comparison of the effects of cyclazocine and imipramine on the circadian sleep-waking cycle of the cat.
    Pharmacology, 1971, Volume: 6, Issue:6

    Topics: Administration, Oral; Analgesics; Animals; Azocines; Behavior, Animal; Cats; Circadian Rhythm; Cyclazocine; Drug Combinations; Drug Tolerance; Electroencephalography; Female; Humans; Imipramine; Male; Narcotic Antagonists; Noise; Sleep; Sleep, REM; Stereotaxic Techniques; Substance Withdrawal Syndrome; Time Factors

1971
[Problems in quantification of provoked morphine withdrawal in rats].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:7

    Topics: Animals; Behavior, Animal; Cyclazocine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Levallorphan; Morphine Dependence; Motor Activity; Naloxone; Rats; Substance Withdrawal Syndrome

1974
On the treatment of stimulant abuse.
    Perspectives in biology and medicine, 1972,Summer, Volume: 15, Issue:4

    Topics: Cyclazocine; Humans; Methadone; Morphine Dependence; Psychotherapy; Reinforcement, Social; Social Change; Social Conditions; Social Problems; Substance Withdrawal Syndrome; Substance-Related Disorders; Therapeutic Community

1972
An implanted reservoir of morphine solution for rapid induction of physical dependence in rats.
    British journal of pharmacology, 1971, Volume: 41, Issue:3

    Topics: Animals; Body Weight; Codeine; Cyclazocine; Defecation; Female; Humans; Injections, Subcutaneous; Methadone; Methods; Morphine; Nalorphine; Pentazocine; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1971
Blockade with methadone, cyclazocine, and naloxone.
    The International journal of the addictions, 1970, Volume: 5, Issue:3

    Topics: Analgesics; Azocines; Cyclazocine; Evaluation Studies as Topic; Heroin; Hospitalization; Hospitals, General; Hospitals, Teaching; Humans; Methadone; Morphinans; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; New York City; Outpatient Clinics, Hospital; Psychotherapy; Substance Withdrawal Syndrome; Substance-Related Disorders

1970
Narcotic antagonists in the treatment of opiate dependence.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Allyl Compounds; Carbamates; Cyclazocine; Ethers, Cyclic; Humans; Male; Methadone; Morphinans; Morphine Dependence; Narcotic Antagonists; Substance Withdrawal Syndrome; Time Factors; Tranquilizing Agents

1971
Physiologic disposition of H3-cyclazocine in nontolerant, tolerant and abstinent dogs.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:3

    Topics: Adrenal Glands; Analgesics; Animals; Central Nervous System; Cerebral Cortex; Cyclazocine; Dogs; Drug Tolerance; Feces; Humans; Kidney; Liver; Lung; Narcotic Antagonists; Spleen; Substance Withdrawal Syndrome

1966