cyclazocine has been researched along with Ache in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (86.84) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 1 (2.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Khrasani, M; Amata, E; Costanzo, G; Dichiara, M; Essmat, N; Galambos, AR; Marrazzo, A; Parenti, C; Pasquinucci, L; Piana, S; Spoto, S; Turnaturi, R; Zagni, C | 1 |
| Domino, EF; Gwynn, GJ | 1 |
| Dickinson, SL; Slater, P | 1 |
| Tung, AS; Yaksh, TL | 1 |
| Sewell, RD; Spencer, PS; Upton, N | 1 |
| Kamerling, SG; Martin, WR; Wettstein, JG; Wu, KM | 2 |
| Han, JS; Xie, GX | 1 |
| Kawajiri, S; Satoh, M | 2 |
| Iwamoto, ET; Martin, WR | 1 |
| Dewey, WL; Snow, AE | 1 |
| Aceto, MD; Awaya, H; Harris, LS; Jacobson, AE; May, EL | 1 |
| Bai, X; Bowen, WD; Carroll, FI; Mascarella, SW; Patrick, SL; Walker, JM; Williams, WE | 1 |
| Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ | 1 |
| Bidlack, JM; McLaughlin, JP; Wentland, MP | 1 |
| Ahtee, L; Kääriäinen, I | 1 |
| Edwards, M; Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Dequick, DJ; Kamerling, SG; Tobin, T; Weckman, TJ | 1 |
| Inoki, R; Kudo, T; Ohkubo, T; Shibata, M; Takahashi, H | 1 |
| Russell, NJ; Schaible, HG; Schmidt, RF | 1 |
| Dickenson, AH; Knox, RJ | 1 |
| Candeletti, S; Cavicchini, E; Ferri, S; Romualdi, P; Spampinato, S; Speroni, E | 1 |
| Abbott, FV | 1 |
| Kitchen, I; McDowell, J | 1 |
| Kameyama, T; Matsuno, K; Nabeshima, T | 1 |
| Hayes, AG; Skingle, M; Tyers, MB | 1 |
| Barr, GA; Erickson, KL; Paredes, W; Zukin, RS | 1 |
| Abbott, FV; Franklin, KB; Libman, RB | 1 |
| Barr, GA; Giordano, J | 2 |
| Belknap, JK; Danielson, PW; Laursen, SE; Noordewier, B | 1 |
| Kornetsky, C; Sasson, S | 1 |
| Rodríguez, R | 1 |
| Resnick, RB | 1 |
| Houser, VP; Paré, WP | 1 |
| Eddy, NB; Friebel, H; Hahn, KJ; Halbach, H | 1 |
| Lasagna, L; Werner, G | 1 |
2 review(s) available for cyclazocine and Ache
| Article | Year |
|---|---|
Multiple opioid receptors.
Topics: Analgesics; Animals; Behavior, Animal; Benzomorphans; Cyclazocine; Discrimination Learning; Dogs; Dopamine; Drug Tolerance; Electroencephalography; Humans; Macaca mulatta; Mice; Morphine; Morphine Dependence; Motor Activity; Nalorphine; Pain; Rabbits; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Temperature | 1981 |
Codeine and its alternates for pain and cough relief. 2. Alternates for pain relief.
Topics: Amides; Analgesics; Animals; Antitussive Agents; Azepines; Carisoprodol; Cats; Chickens; Codeine; Cough; Cyclazocine; Dextropropoxyphene; Diphenylacetic Acids; Dogs; Ducks; Guinea Pigs; Humans; Indenes; Indoles; Isoquinolines; Mice; Morphinans; Nalorphine; Narcotic Antagonists; Pain; Pentazocine; Phenethylamines; Pyrrolidines; Rats; Substance-Related Disorders; Thalidomide | 1969 |
1 trial(s) available for cyclazocine and Ache
| Article | Year |
|---|---|
Conjoint clinic on pain and analgesia.
Topics: Analgesia; Analgesics; Aspirin; Cyclazocine; Humans; Morphine; Narcotic Antagonists; Pain; Phenacetin; Placebos; Salicylates | 1966 |
35 other study(ies) available for cyclazocine and Ache
| Article | Year |
|---|---|
New Insights into the Opioid Analgesic Profile of
Topics: Analgesics, Opioid; Animals; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ligands; Male; Mice; Pain; Rats; Receptors, Opioid, mu | 2023 |
Genotype-dependent behavioral sensitivity to mu vs. kappa opiate agonists. II. Antinociceptive tolerance and physical dependence.
Topics: Analgesics; Animals; Cyclazocine; Drug Tolerance; Ethylketocyclazocine; Genotype; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Opioid-Related Disorders; Pain; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Species Specificity | 1984 |
Opiate receptor antagonism by L-prolyl-L-leucyl-glycinamide, MIF-I.
Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Female; Ileum; In Vitro Techniques; Male; Mice; Morphine; Motor Activity; MSH Release-Inhibiting Hormone; Muscle Contraction; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Vas Deferens | 1980 |
In vivo evidence for multiple opiate receptors mediating analgesia in the rat spinal cord.
Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Injections, Spinal; Male; Naloxone; Pain; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1982 |
Analgesic actions of mu- and kappa-opiate agonists in rats.
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Hot Temperature; Male; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1983 |
Medullary kappa hyperalgesic mechanisms II. The effects of ethylketazocine administered into the fourth cerebral ventricle of the conscious dog.
Topics: Analgesics, Opioid; Animals; Cerebral Ventricles; Cyclazocine; Dogs; Ethylketocyclazocine; Female; Injections; Medulla Oblongata; Pain; Receptors, Opioid; Reflex | 1983 |
Possible medullary kappa hyperalgesic mechanism. I. A new potential role for endogenous opioid peptides in pain perception.
Topics: Animals; Cyclazocine; Dogs; Dynorphins; Endorphins; Ethylketocyclazocine; Medulla Oblongata; Naloxone; Pain; Receptors, Opioid; Reflex | 1983 |
[Dynorphin: analgesic effect via kappa receptors in spinal cord of the spinal cords of rats].
Topics: Analgesics; Animals; Cyclazocine; Dynorphins; Ethylketocyclazocine; Female; Morphine; Naloxone; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sensory Thresholds; Spinal Cord | 1984 |
Temporary spinalization reverses the inhibitory effect of cyclazocine on the nociceptive response of rabbit spinal dorsal horn lamina V-type neurons.
Topics: Animals; Bradykinin; Cyclazocine; Male; Neurons; Pain; Rabbits; Spinal Cord; Synaptic Transmission | 1982 |
A comparison of antinociception induced by foot shock and morphine.
Topics: Animals; Cyclazocine; Electroshock; Foot; Male; Methadone; Morphine; Naloxone; Nociceptors; Pain; Pentazocine; Perception; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord; Time Factors | 1983 |
Agonist-antagonist actions and stereoselectivity of optical pairs of some N-substituted alpha-N-normetazocines.
Topics: Analgesics; Animals; Benzoquinones; Chemical Phenomena; Chemistry; Cyclazocine; Female; Humans; Macaca mulatta; Male; Mice; Morphine Dependence; Narcotic Antagonists; Pain; Quinones; Reaction Time; Stereoisomerism | 1984 |
A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor function.
Topics: Animals; Benzomorphans; Cyclazocine; Male; Motor Activity; Naloxone; Narcotics; Pain; Phenols; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, sigma; Rotation; Stereoisomerism | 1993 |
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1997 |
Partial opioids. Medications for the treatment of pain and drug abuse.
Topics: Analgesics; Animals; Cyclazocine; Male; Mice; Mice, Inbred ICR; Pain; Pentazocine; Stereoisomerism; Structure-Activity Relationship; Substance-Related Disorders | 2000 |
Effect of narcotic analgesics on the striatal homovanillic acid content in mice; relation to antinociceptive effect.
Topics: Analgesics, Opioid; Animals; Body Temperature; Corpus Striatum; Cyclazocine; Haloperidol; Homovanillic Acid; Male; Methadone; Mice; Morphine; Pain; Pentazocine; Phenylacetates; Piperidines; Thebaine; Time Factors | 1976 |
On the mechanism by which midazolam causes spinally mediated analgesia.
Topics: Analgesia, Epidural; Animals; Bicuculline; Cyclazocine; Dose-Response Relationship, Drug; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Male; Midazolam; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds | 1990 |
Dose-related effects of ethylketazocine on nociception, behaviour and autonomic responses in the horse.
Topics: Analgesics, Opioid; Animals; Autonomic Nervous System; Behavior, Animal; Body Temperature; Cyclazocine; Ethylketocyclazocine; Female; Horses; Male; Motor Activity; Pain; Pupil; Reaction Time | 1986 |
[Peripheral analgesic actions of opioid peptides and morphine analogues].
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dynorphins; Enkephalin, Methionine; Ethylketocyclazocine; Levallorphan; Lidocaine; Male; Mice; Morphine; Naloxone; Pain; Peptide Fragments | 1986 |
Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Arthritis; Cats; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ethylketocyclazocine; Morphine; Naloxone; Nociceptors; Pain; Peripheral Nerves; Pyrrolidines | 1987 |
Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn neurones.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Action Potentials; Animals; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Ethylketocyclazocine; Injections, Spinal; Male; Naloxone; Nerve Fibers; Pain; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Skin; Spinal Cord; Time Factors | 1987 |
Investigations on dynorphin structurally-related opioid peptides. I. Impact on nociceptive transmission. II. Regulation of pituitary content.
Topics: Animals; Benzomorphans; Cyclazocine; Dynorphins; Estradiol; Ethylketocyclazocine; Female; Hypothalamo-Hypophyseal System; Male; Ovary; Pain; Pain Measurement; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1988 |
Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin test.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cyclazocine; Ethylketocyclazocine; Formaldehyde; Injections, Intraventricular; Male; Naloxone; Pain; Rats | 1988 |
Impairment of ketocyclazocine antinociception in rats by perinatal lead exposure.
Topics: Animals; Animals, Newborn; Animals, Suckling; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Lead; Lead Poisoning; Pain; Pregnancy; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sensory Thresholds | 1985 |
Involvement of different opioid receptor subtypes in electric shock-induced analgesia and motor suppression in the rat.
Topics: Animals; Cyclazocine; Electroshock; Enkephalin, Methionine; Ethylketocyclazocine; Male; Motor Activity; Naloxone; Pain; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1985 |
Reversal by beta-funaltrexamine of the antinociceptive effect of opioid agonists in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Buprenorphine; Cyclazocine; Ethylketocyclazocine; Fentanyl; Male; Naltrexone; Pain; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Kappa opioid receptor-mediated analgesia in the developing rat.
Topics: Age Factors; Animals; Brain; Cyclazocine; Drug Tolerance; Ethylketocyclazocine; Hot Temperature; Morphine; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
A dose-ratio comparison of mu and kappa agonists in formalin and thermal pain.
Topics: Analgesia; Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Formaldehyde; Hot Temperature; Male; Naloxone; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1986 |
Morphine- and ketocyclazocine-induced analgesia in the developing rat: differences due to type of noxious stimulus and body topography.
Topics: Age Factors; Analgesics; Animals; Animals, Suckling; Central Nervous System; Cyclazocine; Ethylketocyclazocine; Morphine; Naloxone; Pain; Pain Measurement; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1987 |
Effects of neonatal spinal cord serotonin depletion on opiate-induced analgesia in tests of thermal and mechanical pain.
Topics: 5,7-Dihydroxytryptamine; Analgesia; Animals; Animals, Newborn; Cyclazocine; Desipramine; Dihydroxytryptamines; Ethylketocyclazocine; Hot Temperature; Morphine; Pain; Physical Stimulation; Rats; Serotonin; Spinal Cord | 1988 |
Selective breeding for levorphanol-induced antinociception on the hot-plate assay: commonalities in mechanism of action with morphine, pentazocine, ethylketocyclazocine, U-50488H and clonidine in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Clonidine; Cyclazocine; Ethylketocyclazocine; Female; Levorphanol; Male; Mice; Morphine; Narcotics; Pain; Pentazocine; Pyrrolidines | 1987 |
Evidence for a supraspinal analgesic effect with cyclazocine and pentazocine.
Topics: Analgesia; Animals; Cyclazocine; Electroshock; Escape Reaction; Male; Pain; Pentazocine; Rats | 1986 |
Analgesic effects of cyclazocine and morphine microinjected into the rat dorsomedial hypothalamus demonstrated by the bradykinin-induced flexor reflex test.
Topics: Animals; Bradykinin; Cyclazocine; Dorsomedial Hypothalamic Nucleus; Hypothalamus, Middle; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Reflex | 1985 |
[Analgesic properties of narcotic antagonists].
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dogs; Dose-Response Relationship, Drug; Drug Evaluation; Levallorphan; Movement; Nalorphine; Narcotic Antagonists; Opium; Pain; Pentazocine; Rats; Time Factors | 1974 |
Pharmacological adjuncts in the treatment of opiate dependence.
Topics: Cyclazocine; Cyclopropanes; Drug Evaluation; Female; Heroin; Heroin Dependence; Humans; Male; Morphine Derivatives; Naloxone; Narcotic Antagonists; Opium; Pain; Pupil; Respiration; Sleep; Substance-Related Disorders | 1974 |
Measurement of analgesia using a spatial preference test in the rat.
Topics: Analgesia; Animals; Avoidance Learning; Codeine; Cyclazocine; Differential Threshold; Dose-Response Relationship, Drug; Electroshock; Escape Reaction; Housing, Animal; Humans; Male; Meperidine; Models, Biological; Pain; Pentazocine; Psychopharmacology; Rats; Substance-Related Disorders | 1973 |