cyclandelate has been researched along with Migraine Disorders in 6 studies
Cyclandelate: A direct-acting SMOOTH MUSCLE relaxant used to dilate BLOOD VESSELS.
cyclandelate : The ester obtained by formal condensation of mandelic acid and 3,3,5-tricyclohexanol. It is a direct-acting smooth muscle relaxant used to dilate blood vessels.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyclandelate, however, was superior to placebo in a global impression of efficacy rated by the patients and the treating physicians." | 2.70 | Cyclandelate in the prophylaxis of migraine: a placebo-controlled study. ( Diener, HC; Freytag, S; Krupp, P; Milde, K; Schmitt, T; Steitz, G, 2001) |
| "The number of migraine attacks (> or = 50% responders) and the migraine duration/month were compared based on the difference between baseline and the last 4 weeks of prophylactic treatment." | 2.68 | Cyclandelate in the prophylaxis of migraine: a randomized, parallel, double-blind study in comparison with placebo and propranolol. The Study group. ( Diener, HC; Fischer, M; Föh, M; Iaccarino, C; Isler, H; Strenge, H; Taneri, Z; Wedekind, W; Wessely, P, 1996) |
| "Cyclandelate or pizotifen were administered at a dosage of 1600mg/day (800mg/placebo/800mg) or 0." | 2.67 | Efficacy and tolerance of cyclandelate versus pizotifen in the prophylaxis of migraine. ( de Caterina, G; Iaccarino, C; Mastrosimone, F, 1992) |
| "Overall 40 migraine-outpatients participated in this retrospective analysis of prophylactic migraine treatment over 3-8 months with 1600 to 2000 mg cyclandelate daily." | 1.31 | Evidence for neuronal dysfunction in migraine: concurrence between specific qEEG findings and clinical drug response--a retrospective analysis-. ( Dimpfel, W; Todorova, A; Vonderheid-Guth, B; Wedekind, W, 2000) |
| "No difference was detected between migraine with aura and migraine without aura." | 1.30 | Functional imaging of headache - first steps in an objective quantitative classification of migraine. ( Dimpfel, W; Hofmann, HC; Sauer, S; Schellenberg, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diener, HC | 2 |
| Föh, M | 1 |
| Iaccarino, C | 2 |
| Wessely, P | 1 |
| Isler, H | 1 |
| Strenge, H | 1 |
| Fischer, M | 1 |
| Wedekind, W | 2 |
| Taneri, Z | 1 |
| Sauer, S | 1 |
| Schellenberg, R | 1 |
| Hofmann, HC | 1 |
| Dimpfel, W | 2 |
| Vonderheid-Guth, B | 1 |
| Todorova, A | 1 |
| Krupp, P | 1 |
| Schmitt, T | 1 |
| Steitz, G | 1 |
| Milde, K | 1 |
| Freytag, S | 1 |
| Mastrosimone, F | 1 |
| de Caterina, G | 1 |
| Nappi, G | 1 |
| Sandrini, G | 1 |
| Savoini, G | 1 |
| Cavallini, A | 1 |
| de Rysky, C | 1 |
| Micieli, G | 1 |
4 trials available for cyclandelate and Migraine Disorders
| Article | Year |
|---|---|
Cyclandelate in the prophylaxis of migraine: a randomized, parallel, double-blind study in comparison with placebo and propranolol. The Study group.
Topics: Adult; Cyclandelate; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Sche | 1996 |
Cyclandelate in the prophylaxis of migraine: a placebo-controlled study.
Topics: Adolescent; Adult; Cyclandelate; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Di | 2001 |
Efficacy and tolerance of cyclandelate versus pizotifen in the prophylaxis of migraine.
Topics: Adult; Contraindications; Cyclandelate; Double-Blind Method; Female; Humans; Male; Middle Aged; Migr | 1992 |
Comparative efficacy of cyclandelate versus flunarizine in the prophylactic treatment of migraine.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclandelate; Double-Blind Method; Female; Flunarizine; | 1987 |
2 other studies available for cyclandelate and Migraine Disorders
| Article | Year |
|---|---|
Functional imaging of headache - first steps in an objective quantitative classification of migraine.
Topics: Adolescent; Adult; Aged; Alpha Rhythm; Brain Mapping; Case-Control Studies; Cyclandelate; Electroenc | 1997 |
Evidence for neuronal dysfunction in migraine: concurrence between specific qEEG findings and clinical drug response--a retrospective analysis-.
Topics: Adolescent; Adult; Aged; Child; Cyclandelate; Electroencephalography; Female; Humans; Male; Middle A | 2000 |