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cyclandelate and Diabetic Neuropathies

cyclandelate has been researched along with Diabetic Neuropathies in 4 studies

Cyclandelate: A direct-acting SMOOTH MUSCLE relaxant used to dilate BLOOD VESSELS.
cyclandelate : The ester obtained by formal condensation of mandelic acid and 3,3,5-tricyclohexanol. It is a direct-acting smooth muscle relaxant used to dilate blood vessels.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"Cyclandelate has the ability to improve the rheological properties of the blood and therefore may improve blood supply of peripheral nerves."2.67Cyclandelate in diabetic neuropathy. A double-blind, placebo-controlled, randomized, cross-over study. ( Bertelsmann, FW; Drukarch, B; Heimans, JJ; Ijff, GA; Matthaei, I; Nauta, J; Strijers, RL, 1991)
"Previous trials have demonstrated a clinical and electrophysiological improvement of diabetic peripheral polyneuropathy in diabetic patients treated with cyclandelate at a dosage of 1600 mg/day."2.66Clinical experience with cyclandelate in insulin-dependent diabetic patients with neuropathy. ( De Leeuw, IH; Driessens, M; Moeremans, M; Van Rooy, P, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Canal, N1
Comi, G1
Marchettini, P1
Pozza, G1
van der Drift, JH1
Heimans, JJ1
Drukarch, B1
Matthaei, I1
Ijff, GA1
Bertelsmann, FW1
Strijers, RL1
Nauta, J1
De Leeuw, IH1
Van Rooy, P1
Moeremans, M1
Driessens, M1

Trials

3 trials available for cyclandelate and Diabetic Neuropathies

ArticleYear
Effects of cyclandelate on diabetic peripheral neuropathy.
    British journal of clinical practice. Supplement, 1984, Volume: 34

    Topics: Aged; Clinical Trials as Topic; Cyclandelate; Diabetic Neuropathies; Double-Blind Method; Female; Hu

1984
Cyclandelate in diabetic neuropathy. A double-blind, placebo-controlled, randomized, cross-over study.
    Acta neurologica Scandinavica, 1991, Volume: 84, Issue:6

    Topics: Adult; Aged; Cyclandelate; Diabetic Neuropathies; Double-Blind Method; Female; Follow-Up Studies; Hu

1991
Clinical experience with cyclandelate in insulin-dependent diabetic patients with neuropathy.
    Drugs, 1987, Volume: 33 Suppl 2

    Topics: Adult; Aged; Auditory Threshold; Clinical Trials as Topic; Cyclandelate; Diabetes Mellitus, Type 1;

1987

Other Studies

1 other study available for cyclandelate and Diabetic Neuropathies

ArticleYear
Cyclandelate in diabetic radiculoneuropathy.
    Annals of neurology, 1980, Volume: 7, Issue:4

    Topics: Cyclandelate; Diabetic Neuropathies; Follow-Up Studies; Humans; Mandelic Acids; Spinal Nerve Roots

1980