Compounds > cyc 202
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cyc 202 and Melanoma

cyc 202 has been researched along with Melanoma in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Alexiou, P; Fojtík, P; Growková, K; Hejret, V; Jorda, R; Kryštof, V; Palušová, V; Rotrekl, V; Štětková, M; Uldrijan, S; Valčíková, B; Verlande, A1
Coelho, SG; Hearing, VJ; Kaneko, Y; Katayama, I; Kawaguchi, M; Kawakami, Y; Nakamura, K; Namiki, T; Tanemura, A; Valencia, JC; Vieira, WD; Yaguchi, T; Yin, L; Yokozeki, H1
Du, J; Fisher, DE; Golub, TR; Horstmann, MA; Huber, WE; Nishimura, EK; Ramaswamy, S; Ross, K; Widlund, HR1
Coppola, D; Mohapatra, S; Pledger, WJ; Riker, AI1
Ball, HM; Blaydes, JP; Craig, AL; Gibbs, NK; Hupp, TR; Traynor, NJ; Wallace, M1
Horky, M; Kotala, V; Strnad, M; Trbusek, M; Uldrijan, S; Vojtesek, B1
Dong, YB; Elliott, MJ; McMasters, KM; Yang, HL1

Other Studies

7 other study(ies) available for cyc 202 and Melanoma

ArticleYear
CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells.
    Cell death & disease, 2020, 09-15, Volume: 11, Issue:9

    Topics: Animals; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase 9; Drug Synergism; Humans; Imidazoles; MCF-7 Cells; Melanoma; Mice; Piperazines; Pluripotent Stem Cells; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Roscovitine; Sulfonamides; Transcription, Genetic; Transfection; Triazines

2020
NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.
    Cancer research, 2015, Jul-01, Volume: 75, Issue:13

    Topics: Aged; Animals; Cell Growth Processes; Cell Line, Tumor; Cyclin-Dependent Kinase 2; Gene Amplification; Humans; Male; Melanoma; Mice; Mice, Nude; Middle Aged; Molecular Targeted Therapy; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; PTEN Phosphohydrolase; Purines; Roscovitine; Signal Transduction; Skin Neoplasms

2015
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
    Cancer cell, 2004, Volume: 6, Issue:6

    Topics: bcl-X Protein; Blotting, Western; CDC2-CDC28 Kinases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA-Binding Proteins; E-Box Elements; Fibroblasts; Flow Cytometry; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Reporter; gp100 Melanoma Antigen; Humans; Melanocytes; Melanoma; Membrane Glycoproteins; Microphthalmia-Associated Transcription Factor; Mutation; Oligonucleotide Array Sequence Analysis; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins c-bcl-2; Purines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Roscovitine; S Phase; Transcription Factors; Transcription, Genetic; Transfection

2004
Roscovitine inhibits differentiation and invasion in a three-dimensional skin reconstruction model of metastatic melanoma.
    Molecular cancer research : MCR, 2007, Volume: 5, Issue:2

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Humans; Melanoma; Models, Biological; Neoplasm Invasiveness; Protein Kinase Inhibitors; Purines; Roscovitine; Skin Neoplasms; Tissue Culture Techniques

2007
Synergistic activation of p53-dependent transcription by two cooperating damage recognition pathways.
    Oncogene, 2000, Aug-10, Volume: 19, Issue:34

    Topics: Amino Acid Sequence; Cyclin-Dependent Kinases; Dichlororibofuranosylbenzimidazole; DNA Damage; Enzyme Inhibitors; Gene Expression Regulation; Humans; Melanoma; Molecular Sequence Data; Phosphorylation; Purines; RNA Polymerase II; Roscovitine; Serine; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays; X-Rays

2000
Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases.
    Cellular and molecular life sciences : CMLS, 2001, Volume: 58, Issue:9

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Melanoma; Mice; Osteosarcoma; Purines; Recombinant Proteins; Roscovitine; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Adenovirus-mediated E2F-1 gene transfer sensitizes melanoma cells to apoptosis induced by topoisomerase II inhibitors.
    Cancer research, 2002, Mar-15, Volume: 62, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Proteins; Cisplatin; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA-Binding Proteins; Doxorubicin; Drug Synergism; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Etoposide; Fluorouracil; Genetic Therapy; Genetic Vectors; Humans; Male; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Proliferating Cell Nuclear Antigen; Purines; Roscovitine; Topoisomerase II Inhibitors; Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002