Page last updated: 2024-09-04

cyc 202 and Lung Neoplasms

cyc 202 has been researched along with Lung Neoplasms in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (14.29)	18.2507
2000's	4 (19.05)	29.6817
2010's	13 (61.90)	24.3611
2020's	1 (4.76)	2.80

Authors

Authors	Studies
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP	1
Asai, T; Ikari, A; Manabe, A; Matsunaga, T; Onuma, S; Yoshino, Y	1
Behrens, C; Dmitrovsky, E; Freemantle, S; Heymach, JV; Hong, S; Hu, S; Johnson, FM; Kawakami, M; Lee, JJ; Liu, X; Mino, B; Mustachio, LM; Myung, JH; Rodriguez-Canales, J; Roszik, J; Tong, P; Villalobos, PA; Wang, J; Wistuba, I; Zheng, L	1
Cheng, YY; Chuan-Hao Kao, S; Gattani, S; Griggs, K; Kirschner, MB; Klebe, S; Linton, A; McCaughan, BC; Reid, G; Schedlich, L; Srikaran, S; van Zandwijk, N	1
Andrew, AS; Behrens, C; Compton, DA; Danilov, AV; DeCastro, A; Dmitrovsky, E; Freemantle, S; Galimberti, F; Godek, K; Hu, S; Lu, Y; Memoli, VA; Mino, B; Moran, CA; Mustachio, LM; Orr, B; Ravi, S; Rodriguez-Canales, J; Sekula, D; Tafe, LJ; Wistuba, II	1
Gu, RX; Liu, JL; Wu, G; Zhou, FZ; Zhou, XS	1
Compton, DA; Dmitrovsky, E; Freemantle, S; Godek, K; Hu, S; Kawakami, M; Lu, Y; Mustachio, LM; Orr, B; Sekula, D	1
Chia, DM; Chinnathambi, A; Goh, BC; Ho, PC; Kong, LR; Lau, JY; Ong, PS; Seah, JY; Sethi, G; Thuya, WL; Wang, L; Wong, AL; Yang, D; Yong, WP	1
Jiang, T; Li, C; Li, XF; Zhang, F; Zhang, T; Zhou, YA; Zhu, YF	1
Compton, DA; DiRenzo, J; Dmitrovsky, E; Galimberti, F; Green, SR; Greninger, P; Li, H; Liu, X; Memoli, V; Settleman, J; Sharma, SV; Thompson, SL	1
Cwiertka, K; Dzubak, P; Hajduch, M; Korinkova, G; Paprskarova, M	1
Abolmaali, ND; Tokalov, SV	1
Amin, ND; Demelash, A; Linnoila, RI; McWhite, CD; Naizhen, X; Pant, HC; Rudrabhatla, P; Wang, X	1
Slovackova, J; Smarda, J; Smardova, J	1
Barth, P; Göke, R; Lankat-Buttgereit, B; Samans, B; Schmidt, A	1
Henfling, ME; Ramaekers, FC; Schutte, B	1
Cress, WD; Freeman, SN; Ma, Y	1
Fesik, SW; Huang, X; Li, L; Lin, X; Morgan-Lappe, S; Shen, Y; Vernetti, LA; Zakula, DM	1
Kuijpers, HJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; van Engeland, M	1
Henfling, ME; Meijer, L; Nieland, L; Ramaekers, FC; Schutte, B; van Engeland, M	1
Chang, TH; Lee, HR; Senderowicz, AM; Szabo, E; Tebalt, MJ	1

Other Studies

21 other study(ies) available for cyc 202 and Lung Neoplasms

Article	Year
The target landscape of clinical kinase drugs. Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays	2017
Upregulation of Chemoresistance by Mg Cells, 2021, 05-12, Volume: 10, Issue:5 Topics: A549 Cells; Adenocarcinoma of Lung; ATP Binding Cassette Transporter, Subfamily B; Cell Cycle; Cell Proliferation; Cisplatin; Cyclosporins; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Lymph Nodes; Magnesium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species; Roscovitine	2021
Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer. Journal of the National Cancer Institute, 2017, 06-01, Volume: 109, Issue:6 Topics: Adenosine; Anaphase; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Centrosome; Cyclin-Dependent Kinase 2; Gene Knockdown Techniques; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Mice; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Purines; Roscovitine; Signal Transduction	2017
An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma. British journal of cancer, 2014, 01-21, Volume: 110, Issue:2 Topics: Apoptosis; Blood Proteins; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cisplatin; Cytoskeletal Proteins; DNA Repair; DNA Replication; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Molecular Targeted Therapy; Nuclear Proteins; Pleural Neoplasms; Polo-Like Kinase 1; Prognosis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Purines; Retrospective Studies; RNA Interference; Roscovitine	2014
CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110. Cancer research, 2015, May-15, Volume: 75, Issue:10 Topics: Anaphase; Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase 2; Humans; Lung Neoplasms; Mice; Microtubule-Associated Proteins; Mutation; Phosphoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Purines; ras Proteins; Roscovitine	2015
Cyclin-dependent kinase 5 regulates the proliferation, motility and invasiveness of lung cancer cells through its effects on cytoskeletal remodeling. Molecular medicine reports, 2015, Volume: 12, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinase 5; Cytoskeleton; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Microvilli; Purines; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Roscovitine	2015
Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown. Molecular cancer therapeutics, 2015, Volume: 14, Issue:11 Topics: Anaphase; Animals; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Centrosome; Cyclin-Dependent Kinase 2; Cyclins; Humans; Immunoblotting; Lung Neoplasms; Microtubule-Associated Proteins; Mutation; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Purines; RNA Interference; Roscovitine; Serine; Threonine; Ubiquitin Thiolesterase	2015
A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation. Cancer letters, 2016, 10-10, Volume: 381, Issue:1 Topics: A549 Cells; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspase 8; Caspase Inhibitors; Cell Proliferation; Dose-Response Relationship, Drug; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Purines; RNA Interference; Roscovitine; Signal Transduction; Sulfonamides; Time Factors; Transfection; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein	2016
Involvement of p21Waf1/Cip1 cleavage during roscovitine-induced apoptosis in non-small cell lung cancer cells. Oncology reports, 2010, Volume: 23, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; DNA Repair; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Purines; Roscovitine	2010
Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe. Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Jan-01, Volume: 16, Issue:1 Topics: Anaphase; Animals; Antineoplastic Agents; Cell Line, Tumor; Cyclin E; Cyclin-Dependent Kinase 2; Docetaxel; Drug Delivery Systems; Lung Neoplasms; Mice; Mice, Transgenic; Protein Kinase Inhibitors; Purines; Roscovitine; Taxoids	2010
The radiosensitising effect of olomoucine derived synthetic cyclin-dependent kinase inhibitors. Neoplasma, 2010, Volume: 57, Issue:2 Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cell Cycle; Cyclin-Dependent Kinases; Flow Cytometry; Humans; Kinetin; Lung Neoplasms; Protein Kinase Inhibitors; Purines; Radiation-Sensitizing Agents; Roscovitine; Tumor Cells, Cultured; X-Rays	2010
Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment. BMC cancer, 2010, Feb-23, Volume: 10 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Models, Genetic; Mutation; Piperazines; Purines; Roscovitine; Tumor Suppressor Protein p53	2010
Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway. Molecular biology of the cell, 2012, Volume: 23, Issue:15 Topics: Adenocarcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinase 5; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Neoplasm Invasiveness; Nerve Tissue Proteins; Purines; Roscovitine; Signal Transduction; Transcription Factors	2012
Roscovitine-induced apoptosis of H1299 cells depends on functional status of p53. Neoplasma, 2012, Volume: 59, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Humans; Lung Neoplasms; Purines; Roscovitine; Tumor Suppressor Protein p53	2012
Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1). American journal of physiology. Cell physiology, 2004, Volume: 287, Issue:6 Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Carcinoid Tumor; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Endocrine Gland Neoplasms; Female; Humans; Insulinoma; Lung Neoplasms; Male; Pancreatic Neoplasms; Phosphorylation; Prostatic Neoplasms; Protein Kinase Inhibitors; Purines; Retinoblastoma Protein; RNA-Binding Proteins; Roscovitine	2004
Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis. International journal of oncology, 2004, Volume: 25, Issue:5 Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Lung Neoplasms; Membrane Potentials; Mitochondria; Proteasome Endopeptidase Complex; Purines; Roscovitine; Signal Transduction; Tumor Cells, Cultured	2004
E2F4 deficiency promotes drug-induced apoptosis. Cancer biology & therapy, 2004, Volume: 3, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F4 Transcription Factor; Fibroblasts; Flavonoids; Humans; Lung Neoplasms; Mice; Mice, Knockout; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Roscovitine; Thiazoles; Transcription Factors; Tumor Cells, Cultured	2004
'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737. Oncogene, 2007, Jun-07, Volume: 26, Issue:27 Topics: 3' Untranslated Regions; Antineoplastic Agents; Base Sequence; bcl-X Protein; Benzenesulfonates; Biphenyl Compounds; Blotting, Western; Carcinoma, Small Cell; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Niacinamide; Nitrophenols; Phenylurea Compounds; Piperazines; Proto-Oncogene Proteins c-bcl-2; Purines; Pyridines; Receptor, Fibroblast Growth Factor, Type 2; RNA Interference; RNA, Small Interfering; Roscovitine; Sorafenib; Sulfonamides; Transmembrane Activator and CAML Interactor Protein; Zinc Fingers	2007
Plasma membrane alterations and cytoskeletal changes in apoptosis. Experimental cell research, 1997, Sep-15, Volume: 235, Issue:2 Topics: Actins; Annexin A5; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Membrane; Chromatin; Cytoskeleton; Ethylmaleimide; Humans; Keratins; Kinetin; Lung Neoplasms; Neuroblastoma; Phosphatidylserines; Purines; Roscovitine; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Vimentin	1997
The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics. Experimental cell research, 1997, Oct-10, Volume: 236, Issue:1 Topics: Antimetabolites; Apoptosis; Bromodeoxyuridine; Carcinoma, Non-Small-Cell Lung; CDC2 Protein Kinase; Cell Cycle; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; G2 Phase; Humans; Kinetin; Lung Neoplasms; Mitosis; Neuroblastoma; Purines; Roscovitine; S Phase; Tumor Cells, Cultured	1997
Induction of differentiation accompanies inhibition of Cdk2 in a non-small cell lung cancer cell line. International journal of oncology, 1999, Volume: 15, Issue:1 Topics: Carcinoma, Non-Small-Cell Lung; CDC2-CDC28 Kinases; Cell Differentiation; Cell Division; Cyclin D; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Flavonoids; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Proteins; Piperidines; Protein Serine-Threonine Kinases; Purines; Roscovitine; Signal Transduction; Transfection; Tumor Cells, Cultured	1999