Page last updated: 2024-09-04

cyc 202 and Kidney, Polycystic

cyc 202 has been researched along with Kidney, Polycystic in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (63.64)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alkanderi, S; Filby, A; Henry, C; Miles, CG; Molinari, E; Ramsbottom, SA; Saunier, S; Sayer, JA; Srivastava, S; White, K1
Billot, K; Boletta, A; Bukanov, N; Coquil, C; Delehouzé, C; Desban, N; Fautrel, A; Fischer, E; Grosch, M; Ibraghimov-Beskrovnaya, O; Josselin-Foll, B; Le Meur, Y; Meijer, L; Mrug, M; Oumata, N; Pontoglio, M; Saunier, S; Tran, PV; Trudel, M; Villiers, B; Wallace, D; Weimbs, T; Witzgall, R1
Deen, PM; Devuyst, O; Di Mise, A; Lasorsa, D; Mastrofrancesco, L; Mola, MG; Ranieri, M; Svelto, M; Tamma, G; Trimpert, C; Valenti, G1
Beier, DR; Billot, K; Bukanov, NO; Carlson, G; Husson, H; Ibraghimov-Beskrovnaya, O; Lane, M; Ledbetter, SR; Meijer, L; Moreno, S; Pitstick, R; Russo, RJ; Sergeev, M; Shah, J; Smith, LA; Smith, MM; Zhang, K1
Bukanov, NO; Ibraghimov-Beskrovnaya, O; Moreno, S1
Beales, PL; Tobin, JL1
Chowdhury, R; Igarashi, P; Patel, V1
Bukanov, NO; Ibraghimov-Beskrovnaya, O; Klinger, KW; Ledbetter, SR; Smith, LA1
Ibraghimov-Beskrovnaya, O1
Kuehn, EW; Walz, G1
Bukanov, NO; Dackowski, WR; Gareski, TC; Husson, H; Ibraghimov-Beskrovnaya, O; Matthews, D; Natoli, TA; Piepenhagen, P; Russo, RJ; Smith, L1

Reviews

3 review(s) available for cyc 202 and Kidney, Polycystic

ArticleYear
Advances in the pathogenesis and treatment of polycystic kidney disease.
    Current opinion in nephrology and hypertension, 2009, Volume: 18, Issue:2

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Cell Polarity; Cilia; Humans; Kinesins; Octreotide; Polycystic Kidney Diseases; Purines; Roscovitine; Sirolimus; TRPP Cation Channels

2009
Targeting dysregulated cell cycle and apoptosis for polycystic kidney disease therapy.
    Cell cycle (Georgetown, Tex.), 2007, Apr-01, Volume: 6, Issue:7

    Topics: Animals; Apoptosis; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Cyclin-Dependent Kinases; Enzyme Inhibitors; Genes, cdc; Humans; Mice; Polycystic Kidney Diseases; Purines; Roscovitine

2007
Prime time for polycystic kidney disease: does one shot of roscovitine bring the cure?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:8

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Clinical Trials as Topic; Disease Models, Animal; Genes, Dominant; Humans; Mice; Models, Biological; Polycystic Kidney Diseases; Protein Kinase Inhibitors; Protein Kinases; Purines; Roscovitine; TOR Serine-Threonine Kinases

2007

Other Studies

8 other study(ies) available for cyc 202 and Kidney, Polycystic

ArticleYear
A human patient-derived cellular model of Joubert syndrome reveals ciliary defects which can be rescued with targeted therapies.
    Human molecular genetics, 2017, 12-01, Volume: 26, Issue:23

    Topics: Abnormalities, Multiple; Antigens, Neoplasm; Cell Cycle Proteins; Cerebellum; Child; Child, Preschool; Cilia; Ciliopathies; Cyclin-Dependent Kinase 5; Cytoskeletal Proteins; Epithelial Cells; Eye Abnormalities; Humans; Kidney Diseases, Cystic; Kidney Failure, Chronic; Male; Morpholines; Mutation; Neoplasm Proteins; Pedigree; Polycystic Kidney Diseases; Primary Cell Culture; Purines; Retina; Roscovitine; Signal Transduction

2017
Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.
    American journal of physiology. Renal physiology, 2018, 07-01, Volume: 315, Issue:1

    Topics: Animals; Casein Kinase 1 epsilon; Casein Kinase Ialpha; Catalysis; Chromatography, Affinity; Disease Models, Animal; Humans; Kidney; Mice, Transgenic; Polycystic Kidney Diseases; Protein Binding; Protein Kinase Inhibitors; Purines; Pyridines; Roscovitine; Signal Transduction

2018
A protein kinase A-independent pathway controlling aquaporin 2 trafficking as a possible cause for the syndrome of inappropriate antidiuresis associated with polycystic kidney disease 1 haploinsufficiency.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:10

    Topics: Animals; Aquaporin 2; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinases; Haploinsufficiency; In Vitro Techniques; Male; Mice; Polycystic Kidney Diseases; Protein Phosphatase 2; Purines; Rats, Sprague-Dawley; Roscovitine; Vasopressins

2014
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
    Human molecular genetics, 2016, 06-01, Volume: 25, Issue:11

    Topics: Animals; Cell Differentiation; Cilia; Cyclin-Dependent Kinase 5; Disease Models, Animal; Humans; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Failure, Chronic; Mice; Nerve Tissue Proteins; Polycystic Kidney Diseases; Purines; Roscovitine; Tubulin

2016
Serum and urinary biomarker signatures for rapid preclinical in vivo assessment of CDK inhibition as a therapeutic approach for PKD.
    Cell cycle (Georgetown, Tex.), 2008, Jun-15, Volume: 7, Issue:12

    Topics: Animals; Biomarkers; Blood Proteins; Cyclin-Dependent Kinases; Disease Models, Animal; Mice; Mice, Inbred C57BL; Polycystic Kidney Diseases; Protein Kinase Inhibitors; Proteins; Purines; Roscovitine; Treatment Outcome

2008
Restoration of renal function in zebrafish models of ciliopathies.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:11

    Topics: Animals; Antineoplastic Agents; Bardet-Biedl Syndrome; Cilia; Disease Models, Animal; Immunosuppressive Agents; Kidney; Polycystic Kidney Diseases; Purines; Recovery of Function; Roscovitine; Sirolimus; Zebrafish

2008
Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.
    Nature, 2006, Dec-14, Volume: 444, Issue:7121

    Topics: Animals; Apoptosis; Cyclin-Dependent Kinases; Disease Models, Animal; Disease Progression; Kidney; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Polycystic Kidney Diseases; Purines; Roscovitine; Time Factors

2006
Pkd1 and Nek8 mutations affect cell-cell adhesion and cilia in cysts formed in kidney organ cultures.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:1

    Topics: Alleles; Animals; Cadherins; Cell Adhesion; Cilia; Cyclin-Dependent Kinases; Cysts; Disease Models, Animal; Female; Male; Mice; Mice, Knockout; Mutation; NIMA-Related Kinases; Organ Culture Techniques; Polycystic Kidney Diseases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Purines; Roscovitine; TRPP Cation Channels

2008