cyc 202 has been researched along with Chemical and Drug Induced Liver Injury in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, KX; Fan, S; Fu, R; Huang, H; Huang, J; Li, GM; Li, J; Liao, L; Liu, Y; Luo, C; Shi, C; Yu, L; Zhang, YY | 1 |
| Filipski, E; Guettier, C; Harper, F; Hassan, M; Iacobelli, S; Iurisci, I; Lévi, F; Maire, I; Sallam, H | 1 |
| Graña, X; Knudsen, ES; Mayhew, CN; Reed, CA; Rivadeneira, DB; Sotillo, E; Thangavel, C | 1 |
| Armour, S; Chiao, J; Delbaldo, C; Diéras, V; Faivre, S; Frame, S; Gianella-Borradori, A; Girre, V; Green, SR; Laurence, V; Le Tourneau, C; Raymond, E; Vera, K | 1 |
1 trial(s) available for cyc 202 and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Phase I evaluation of seliciclib (R-roscovitine), a novel oral cyclin-dependent kinase inhibitor, in patients with advanced malignancies.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Maximum Tolerated Dose; Metabolic Diseases; Middle Aged; Nausea; Neoplasms; Purines; Roscovitine; Vomiting | 2010 |
4 other study(ies) available for cyc 202 and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury.
Topics: Animals; Carbon Tetrachloride; Cell Line; Chemical and Drug Induced Liver Injury; Galactosamine; Humans; Inflammation; Lipopolysaccharides; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; RAW 264.7 Cells; Roscovitine; Sequence Analysis, RNA | 2021 |
Liver circadian clock, a pharmacologic target of cyclin-dependent kinase inhibitor seliciclib.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Biological Clocks; Cell Cycle; Chemical and Drug Induced Liver Injury; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Gene Expression Regulation; Liver; Male; Mice; Purines; Roscovitine | 2009 |
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.
Topics: Adenovirus E1A Proteins; Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Disease Models, Animal; E2F Transcription Factors; Gene Knockdown Techniques; Hep G2 Cells; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Mice, Knockout; Mice, Nude; Neoplasm Transplantation; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; RNA Interference; Roscovitine; Time Factors; Transfection | 2010 |