Page last updated: 2024-09-04

cyc 202 and Brain Ischemia

cyc 202 has been researched along with Brain Ischemia in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Amara, A; Le Roux, C; Le Roy, L; Letondor, A; Timsit, S1
Courbebaisse, Y; Létondor, A; Menn, B; Quillé, ML; Rousselet, E; Timsit, S1
Gao, C; Gao, L; Luo, X; Yan, J; Zhao, C; Zhao, J; Zhao, W; Zhu, X1
Di, Q; Xu, L; Zhang, Y1
Chen, C; Dong, Q; Lü, J; Luo, X; Pan, D; Wang, W; Xie, M; Yu, Z; Zhang, Q1
Bach, S; Blevins, TL; Campbell, M; Meijer, L; Menn, B; Timsit, S1
Menn, B; Timsit, S1
Brun-Zinkernagel, AM; Koulen, P; Liu, R; Simpkins, JW; Wen, Y; Yang, S1
Schmid, G; Strosznajder, JB; Wesierska-Gadek, J1

Reviews

2 review(s) available for cyc 202 and Brain Ischemia

ArticleYear
Cellular and Molecular Mechanisms of R/S-Roscovitine and CDKs Related Inhibition under Both Focal and Global Cerebral Ischemia: A Focus on Neurovascular Unit and Immune Cells.
    Cells, 2021, 01-08, Volume: 10, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cyclin-Dependent Kinases; Humans; Leukocytes; Models, Biological; Roscovitine

2021
Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors.
    Molecular neurobiology, 2006, Volume: 34, Issue:1

    Topics: Animals; Apoptosis; Brain Ischemia; Cell Cycle; Cyclin-Dependent Kinase 5; Humans; Kinetin; Neurodegenerative Diseases; Neurons; Protein Kinase Inhibitors; Purines; Roscovitine; Tumor Suppressor Protein p53

2006

Other Studies

7 other study(ies) available for cyc 202 and Brain Ischemia

ArticleYear
Sustained (S)-roscovitine delivery promotes neuroprotection associated with functional recovery and decrease in brain edema in a randomized blind focal cerebral ischemia study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2018, Volume: 38, Issue:6

    Topics: Animals; Brain Edema; Brain Ischemia; Male; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Roscovitine

2018
Cdk5 is required for the neuroprotective effect of transforming growth factor-β1 against cerebral ischemia-reperfusion.
    Biochemical and biophysical research communications, 2017, 04-15, Volume: 485, Issue:4

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain Ischemia; Cell Differentiation; Cell Proliferation; Cyclin-Dependent Kinase 5; Indazoles; MAP Kinase Signaling System; Neurites; Neuroprotective Agents; PC12 Cells; Piperazines; Protein Kinase Inhibitors; Purines; Rats; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Roscovitine; Transforming Growth Factor beta1

2017
Cell cycle proteins preceded neuronal death after chronic cerebral hypoperfusion in rats.
    Neurological research, 2008, Volume: 30, Issue:9

    Topics: Animals; Apoptosis; Blotting, Western; Brain; Brain Damage, Chronic; Brain Ischemia; Carotid Artery, Common; Cell Cycle Proteins; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 4; Disease Models, Animal; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intraventricular; Ligation; Male; Maze Learning; Memory; Neurons; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; Roscovitine; Spatial Behavior; Time Factors

2008
Cell cycle inhibition attenuates microglial proliferation and production of IL-1beta, MIP-1alpha, and NO after focal cerebral ischemia in the rat.
    Glia, 2009, Volume: 57, Issue:8

    Topics: Animals; Aquaporins; Brain Ischemia; Cell Count; Cell Cycle; Cell Line, Transformed; Cell Proliferation; Disease Models, Animal; Eye Proteins; In Situ Nick-End Labeling; Injections, Intraventricular; Interleukin-1beta; Male; Mice; Microglia; Neurologic Examination; Nitric Oxide; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; Roscovitine; Tetrazolium Salts; Up-Regulation

2009
Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models.
    PloS one, 2010, Aug-12, Volume: 5, Issue:8

    Topics: Animals; Brain Ischemia; Cell Death; Chemistry, Pharmaceutical; Cyclin-Dependent Kinase 5; Disease Models, Animal; Drug Administration Routes; Humans; Injections; Male; Mice; Mitosis; Neuroprotective Agents; Purines; Rats; Roscovitine; Stroke; Time Factors

2010
Cyclin-dependent kinase inhibition with roscovitine: neuroprotection in acute ischemic stroke.
    Clinical pharmacology and therapeutics, 2012, Volume: 91, Issue:2

    Topics: Animals; Brain Ischemia; Clinical Trials as Topic; Cyclin-Dependent Kinases; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Models, Biological; Neuroprotective Agents; Protein Kinase Inhibitors; Purines; Roscovitine; Stroke

2012
Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Alzheimer Disease; Animals; Antigens; Apoptosis; Brain Ischemia; Cell Cycle; Cell Death; Cerebral Cortex; Enzyme Inhibitors; Epitopes; Estradiol; Female; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Ischemia; Microscopy, Electron; Microscopy, Fluorescence; Mitosis; Neurons; Phosphorylation; Protein Conformation; Protein Kinases; Purines; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Roscovitine; Tauopathies; Time Factors

2004