Page last updated: 2024-09-04

cyc 202 and Alzheimer Disease

cyc 202 has been researched along with Alzheimer Disease in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Beauchard, A; Besson, T; Ferandin, Y; Guguen-Guillouzo, C; Laborie, H; Le Guével, R; Lozach, O; Meijer, L; Rouillard, H; Thiéry, V1
Feng, J; Hou, J; Li, M; Li, X; Quan, Q; Zhang, B1
He, CX; Hu, F; Huang, HZ; Li, K; Liu, D; Liu, FF; Wang, JZ; Xie, AJ; Zhu, LQ1
Sadleir, KR; Vassar, R1
Huttunen, HJ; Kysenius, K; Nykänen, NP; Sakha, P; Tammela, P1
Benfenati, F; Chami, M; Checler, F; Del Prete, D; Greco, B; Lauritzen, I; Moreno, S; Oulès, B; Paterlini-Bréchot, P; Sevalle, J; Trebak, M; Zhang, X1
Li, B; Liu, F; Ni, B; Ryder, J; Su, Y; Zhou, Y1
Brun-Zinkernagel, AM; Koulen, P; Liu, R; Simpkins, JW; Wen, Y; Yang, S1
Bäckström, A; Cowburn, RF; Hasslund, K; Jämsä, A; Vasänge, M1
Green, KN; Kitazawa, M; LaFerla, FM; Oddo, S; Yamasaki, TR1
Ackerley, S; Brownlees, J; Kesavapany, S; Lau, KF; Leigh, PN; McLoughlin, DM; Miller, CC; Shaw, CE1

Other Studies

11 other study(ies) available for cyc 202 and Alzheimer Disease

ArticleYear
Synthesis and kinase inhibitory activity of novel substituted indigoids.
    Bioorganic & medicinal chemistry, 2009, Sep-01, Volume: 17, Issue:17

    Topics: Alzheimer Disease; Casein Kinase I; Cyclin B1; Cyclin-Dependent Kinase 5; Dyrk Kinases; Glycogen Synthase Kinase 3; Humans; Indoles; Neuroprotective Agents; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases

2009
Ginsenoside Rg1 reduces β‑amyloid levels by inhibiting CDΚ5‑induced PPARγ phosphorylation in a neuron model of Alzheimer's disease.
    Molecular medicine reports, 2020, Volume: 22, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Cyclin-Dependent Kinase 5; Female; Gene Expression Regulation; Ginsenosides; Hippocampus; Male; Models, Biological; Phosphorylation; PPAR gamma; Primary Cell Culture; Rats; Roscovitine; Signal Transduction

2020
Olfactory Deprivation Hastens Alzheimer-Like Pathologies in a Human Tau-Overexpressed Mouse Model via Activation of cdk5.
    Molecular neurobiology, 2016, Volume: 53, Issue:1

    Topics: Alzheimer Disease; Animals; Calpain; Cholinergic Neurons; Cyclin-Dependent Kinase 5; Dendrites; Disease Models, Animal; Enzyme Activation; Humans; Mice; Olfactory Bulb; Phosphorylation; Purines; Roscovitine; Septal Nuclei; Solubility; tau Proteins; Tauopathies

2016
Cdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.
    The Journal of biological chemistry, 2012, Mar-02, Volume: 287, Issue:10

    Topics: Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Caspase 3; Cells, Cultured; Cyclin-Dependent Kinase 5; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Neurons; Oligopeptides; Protein Kinase Inhibitors; Purines; Roscovitine

2012
γ-Aminobutyric acid type A (GABAA) receptor activation modulates tau phosphorylation.
    The Journal of biological chemistry, 2012, Feb-24, Volume: 287, Issue:9

    Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Cytoskeleton; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Marine Toxins; Mice; Naphthoquinones; Nerve Degeneration; Neuroblastoma; NIMA-Interacting Peptidylprolyl Isomerase; Oxazoles; Peptidylprolyl Isomerase; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 2; Purines; Rats; Receptors, GABA-A; Roscovitine; tau Proteins; Tauopathies

2012
Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-22, Volume: 32, Issue:34

    Topics: Alzheimer Disease; Aminophenols; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Brain; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Dantrolene; Disease Models, Animal; Embryo, Mammalian; Endoplasmic Reticulum; Enzyme Inhibitors; Exploratory Behavior; Gene Expression Regulation; Humans; Inositol 1,4,5-Trisphosphate Receptors; Maleimides; Maze Learning; Membrane Potentials; Membrane Proteins; Memory Disorders; Mice; Mice, Transgenic; Muscle Relaxants, Central; Mutation; Nerve Tissue Proteins; Neuroblastoma; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Plaque, Amyloid; Purines; Reaction Time; Recognition, Psychology; RNA, Messenger; Roscovitine; Ryanodine Receptor Calcium Release Channel; Transfection

2012
Divergent roles of GSK3 and CDK5 in APP processing.
    Biochemical and biophysical research communications, 2003, Dec-26, Volume: 312, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Lithium; Mice; Mice, Transgenic; Purines; Roscovitine

2003
Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Alzheimer Disease; Animals; Antigens; Apoptosis; Brain Ischemia; Cell Cycle; Cell Death; Cerebral Cortex; Enzyme Inhibitors; Epitopes; Estradiol; Female; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Ischemia; Microscopy, Electron; Microscopy, Fluorescence; Mitosis; Neurons; Phosphorylation; Protein Conformation; Protein Kinases; Purines; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Roscovitine; Tauopathies; Time Factors

2004
The retinoic acid and brain-derived neurotrophic factor differentiated SH-SY5Y cell line as a model for Alzheimer's disease-like tau phosphorylation.
    Biochemical and biophysical research communications, 2004, Jul-02, Volume: 319, Issue:3

    Topics: Alzheimer Disease; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line, Tumor; Cell Size; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Neurofibrillary Tangles; Phosphorylation; Purines; Roscovitine; Serine; tau Proteins; Tretinoin

2004
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-28, Volume: 25, Issue:39

    Topics: Aging; Alzheimer Disease; Animals; Cyclin-Dependent Kinase 5; Disease Models, Animal; Encephalitis; Enzyme Activation; Female; Hippocampus; Lipopolysaccharides; Male; Mice; Mice, Transgenic; Microglia; Neural Pathways; Phosphorylation; Protein Kinase Inhibitors; Purines; Roscovitine; tau Proteins; Tauopathies

2005
p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction.
    The European journal of neuroscience, 2001, Volume: 13, Issue:2

    Topics: Alzheimer Disease; Animals; beta Catenin; Calpain; Cerebral Cortex; CHO Cells; Cricetinae; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cytoskeletal Proteins; Enzyme Inhibitors; Humans; Kidney; Membrane Proteins; Nerve Degeneration; Nerve Tissue Proteins; Phosphorylation; Presenilin-1; Protein Binding; Purines; Rats; Roscovitine; Trans-Activators

2001