cyc 202 has been researched along with ADPKD in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JY; Park, SH; Weiss, RH | 1 |
| Chang, MY; Ong, AC | 1 |
| Bukanov, NO; Galons, H; Ibraghimov-Beskrovnaya, O; Ledbetter, SR; Meijer, L; Moreno, SE; Natoli, TA; Oumata, N; Rogers, KA; Smith, LA | 1 |
| Anderson, S; Bagby, SP; Lindsley, JN; Oyama, TT; Park, JY; Schutzer, WE; Weiss, RH | 1 |
1 review(s) available for cyc 202 and ADPKD
| Article | Year |
|---|---|
Mechanism-based therapeutics for autosomal dominant polycystic kidney disease: recent progress and future prospects.
Topics: Aniline Compounds; Antihypertensive Agents; Benzazepines; Clinical Trials as Topic; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Depression, Chemical; Disease Management; Double-Blind Method; Drugs, Investigational; Forecasting; Histone Deacetylase Inhibitors; Humans; Multicenter Studies as Topic; Nitriles; Polycystic Kidney, Autosomal Dominant; Purines; Quinolines; Randomized Controlled Trials as Topic; Roscovitine; Signal Transduction; Somatostatin; Tolvaptan; TOR Serine-Threonine Kinases; Translational Research, Biomedical | 2012 |
3 other study(ies) available for cyc 202 and ADPKD
| Article | Year |
|---|---|
Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: implications for autosomal dominant polycystic kidney disease.
Topics: Animals; Apoptosis; Cell Line; Cellular Senescence; Cyclin-Dependent Kinases; Dogs; Epithelial Cells; Humans; Kidney Tubules; Polycystic Kidney, Autosomal Dominant; Purines; Roscovitine | 2009 |
CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.
Topics: Adenine; Animals; Apoptosis; Cyclin-Dependent Kinases; Disease Models, Animal; Humans; Kidney Diseases, Cystic; Liver Diseases; Mice; Mice, Knockout; Polycystic Kidney, Autosomal Dominant; Protein Kinase C; Protein Kinase Inhibitors; Purines; Roscovitine | 2012 |
p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels.
Topics: Animals; Cell Cycle; Cell Line; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dogs; Epithelial Cells; Humans; Kidney Tubules; Male; Polycystic Kidney, Autosomal Dominant; Purines; Rats; Roscovitine | 2007 |