Page last updated: 2024-09-04

cyc 202 and ADPKD

cyc 202 has been researched along with ADPKD in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, JY; Park, SH; Weiss, RH1
Chang, MY; Ong, AC1
Bukanov, NO; Galons, H; Ibraghimov-Beskrovnaya, O; Ledbetter, SR; Meijer, L; Moreno, SE; Natoli, TA; Oumata, N; Rogers, KA; Smith, LA1
Anderson, S; Bagby, SP; Lindsley, JN; Oyama, TT; Park, JY; Schutzer, WE; Weiss, RH1

Reviews

1 review(s) available for cyc 202 and ADPKD

ArticleYear
Mechanism-based therapeutics for autosomal dominant polycystic kidney disease: recent progress and future prospects.
    Nephron. Clinical practice, 2012, Volume: 120, Issue:1

    Topics: Aniline Compounds; Antihypertensive Agents; Benzazepines; Clinical Trials as Topic; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Depression, Chemical; Disease Management; Double-Blind Method; Drugs, Investigational; Forecasting; Histone Deacetylase Inhibitors; Humans; Multicenter Studies as Topic; Nitriles; Polycystic Kidney, Autosomal Dominant; Purines; Quinolines; Randomized Controlled Trials as Topic; Roscovitine; Signal Transduction; Somatostatin; Tolvaptan; TOR Serine-Threonine Kinases; Translational Research, Biomedical

2012

Other Studies

3 other study(ies) available for cyc 202 and ADPKD

ArticleYear
Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: implications for autosomal dominant polycystic kidney disease.
    American journal of nephrology, 2009, Volume: 29, Issue:6

    Topics: Animals; Apoptosis; Cell Line; Cellular Senescence; Cyclin-Dependent Kinases; Dogs; Epithelial Cells; Humans; Kidney Tubules; Polycystic Kidney, Autosomal Dominant; Purines; Roscovitine

2009
CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD.
    Cell cycle (Georgetown, Tex.), 2012, Nov-01, Volume: 11, Issue:21

    Topics: Adenine; Animals; Apoptosis; Cyclin-Dependent Kinases; Disease Models, Animal; Humans; Kidney Diseases, Cystic; Liver Diseases; Mice; Mice, Knockout; Polycystic Kidney, Autosomal Dominant; Protein Kinase C; Protein Kinase Inhibitors; Purines; Roscovitine

2012
p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels.
    BMC nephrology, 2007, Aug-22, Volume: 8

    Topics: Animals; Cell Cycle; Cell Line; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dogs; Epithelial Cells; Humans; Kidney Tubules; Male; Polycystic Kidney, Autosomal Dominant; Purines; Rats; Roscovitine

2007