cyanogen bromide has been researched along with Brittle Bone Disease in 25 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (44.00) | 18.7374 |
1990's | 13 (52.00) | 18.2507 |
2000's | 1 (4.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Galicka, A; Gindzieński, A; Wołczyński, S | 1 |
Glanville, RW; Kirsch, E; Krieg, T; Müller, P | 1 |
Deak, SB; Nicholls, A; Pope, FM; Prockop, DJ | 1 |
Bateman, JF; Chan, D; Cole, WG; Mascara, T | 2 |
Kaffe, S; Prockop, DJ; Sippola, M | 1 |
Harper, E; Hill, RJ | 1 |
Atkinson, M; Byers, PH; Culbert, AA; Kadler, KE; Lowe, MP; Wallis, GA | 1 |
Cetta, G; Forlino, A; Mottes, M; Pignatti, PF; Rossi, A; Sangalli, A; Tenni, R; Valli, M | 1 |
Marini, JC; Orrison, BM; Wang, Q | 1 |
Chen, KJ; Lewis, MB; Marini, JC; Orrison, BM; Wang, Q | 1 |
Francis, MJ; Pocock, AE; Smith, R | 1 |
Cabral, WA; Choi, H; Forlino, A; Gajko, A; Marini, JC; Reing, CM; Sarafova, AP; Tosi, L | 1 |
Deyl, Z; Hausmann, J; Kalinin, VN; Marik, I; Sher, BM; Sokolov, BP | 1 |
Gottesman, GS; Grange, DK; Lewis, MB; Marini, JC | 1 |
Biglino, P; Borrone, C; Brunelli, P; Buttitta, P; Cetta, G; Dyne, K; Filocamo, M; Pendola, F; Rossi, A; Tenni, R | 1 |
Brenner, RE; Müller, PK; Nerlich, A; Teller, WM; Vetter, U; Wörsdorfer, O | 1 |
Byers, PH; Schwartz, MF; Starman, BJ; Wallis, GA | 1 |
Barr, M; Bonadio, J; Ramirez, F | 1 |
Borrone, C; Filocamo, M; Lituania, M; Pendola, F; Steinmann, B; Superti-Furga, A | 1 |
Bonadio, J; Byers, PH; Gelinas, RE; Holbrook, KA; Jacob, J | 1 |
Bateman, JF; Chan, D; Cole, WG; Rogers, JG; Walker, ID | 1 |
Castellani, AA; Cetta, G; Dyne, K; Lenzi, L; Quacci, D; Rossi, A; Tenni, R | 1 |
Nicholls, A; Pope, FM; Steinmann, B | 1 |
de Vries, WN; de Wet, WJ | 1 |
25 other study(ies) available for cyanogen bromide and Brittle Bone Disease
Article | Year |
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Studies on type I collagen in skin fibroblasts cultured from twins with lethal osteogenesis imperfecta.
Topics: Aspartic Acid; Base Sequence; Cells, Cultured; Collagen Type I; Cyanogen Bromide; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Histidine; Humans; Infant; Osteogenesis Imperfecta; Peptide Fragments; Point Mutation; Procollagen; Proline; Skin; Trypsin; Twins | 2003 |
Analysis of cyanogen bromide peptides of type I collagen from a patient with lethal osteogenesis imperfecta.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Gel; Collagen; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Humans; Hydroxylysine; Infant; Lysine; Osteogenesis Imperfecta; Peptide Fragments | 1983 |
The molecular defect in a nonlethal variant of osteogenesis imperfecta. Synthesis of pro-alpha 2(I) chains which are not incorporated into trimers of type I procollagen.
Topics: 2,2'-Dipyridyl; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Macromolecular Substances; Osteogenesis Imperfecta; Pepsin A; Peptide Fragments; Procollagen | 1983 |
Abnormal type I collagen metabolism by cultured fibroblasts in lethal perinatal osteogenesis imperfecta.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Collagen; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Infant, Newborn; Lysine; Osteogenesis Imperfecta; Peptide Fragments; Procollagen; Proline; Protein Biosynthesis; Skin | 1984 |
A heterozygous defect for structurally altered pro-alpha 2 chain of type I procollagen in a mild variant of osteogenesis imperfecta. The altered structure decreases the thermal stability of procollagen and makes it resistant to procollagen N-proteinase.
Topics: Adult; Child, Preschool; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Female; Fibroblasts; Heterozygote; Humans; Male; Osteogenesis Imperfecta; Pedigree; Peptide Fragments; Procollagen; Procollagen N-Endopeptidase; Time Factors | 1984 |
Quantitation of types I and III collagens in human tissue samples and cell culture by cyanogen bromide peptide analysis.
Topics: Aged; Aorta; Cells, Cultured; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Collagen; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Female; Fibroblasts; Humans; Infant, Newborn; Osteogenesis Imperfecta; Peptide Fragments; Placenta | 1984 |
Substitutions of aspartic acid for glycine-220 and of arginine for glycine-664 in the triple helix of the pro alpha 1(I) chain of type I procollagen produce lethal osteogenesis imperfecta and disrupt the ability of collagen fibrils to incorporate crystall
Topics: Adult; Arginine; Aspartic Acid; Bone and Bones; Calcification, Physiologic; Collagen; Cyanogen Bromide; Durapatite; Electrophoresis, Polyacrylamide Gel; Female; Glycine; Heterozygote; Humans; Macromolecular Substances; Mutation; Osteogenesis Imperfecta; Peptide Mapping; Pregnancy; Procollagen; Protein Structure, Secondary | 1995 |
Osteogenesis imperfecta and type-I collagen mutations. A lethal variant caused by a Gly910-->Ala substitution in the alpha 1 (I) chain.
Topics: Alanine; Collagen; Cyanogen Bromide; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Electrophoresis, Polyacrylamide Gel; Female; Fibroblasts; Glycine; Humans; Infant, Newborn; Osteogenesis Imperfecta; Peptide Mapping; Point Mutation; Sequence Analysis, DNA; Trypsin | 1993 |
Two additional cases of osteogenesis imperfecta with substitutions for glycine in the alpha 2(I) collagen chain. A regional model relating mutation location with phenotype.
Topics: Amino Acid Sequence; Base Sequence; Child, Preschool; Collagen; Cyanogen Bromide; DNA; Female; Glycine; Humans; Molecular Sequence Data; Osteogenesis Imperfecta; Phenotype; Point Mutation; RNA | 1993 |
Serine for glycine substitutions in type I collagen in two cases of type IV osteogenesis imperfecta (OI). Additional evidence for a regional model of OI pathophysiology.
Topics: Amino Acid Sequence; Base Sequence; Child; Child, Preschool; Collagen; Cyanogen Bromide; Female; Glycine; Humans; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Osteogenesis Imperfecta; Peptide Fragments; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Procollagen; Protein Denaturation; RNA, Messenger; Serine | 1993 |
Type 1 collagen synthesis by skin fibroblasts from 17 patients with osteogenesis imperfecta type III.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Collagen; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Female; Fibroblasts; Heterozygote; Humans; Male; Osteogenesis Imperfecta; Phenotype; Procollagen; Skin; Spectrometry, Fluorescence | 1995 |
Three novel type I collagen mutations in osteogenesis imperfecta type IV probands are associated with discrepancies between electrophoretic migration of osteoblast and fibroblast collagen.
Topics: Adolescent; Amino Acid Sequence; Cells, Cultured; Child; Child, Preschool; Collagen; Cyanogen Bromide; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Female; Femur; Fibroblasts; Genes, Dominant; Glycine; Humans; Male; Osteoblasts; Osteogenesis Imperfecta; Point Mutation; Polymorphism, Single-Stranded Conformational; Radiography; Sequence Analysis, DNA; Temperature | 1998 |
Altered ratio of collagen chains in bone of a patient with non-lethal osteogenesis imperfecta.
Topics: Bone and Bones; Collagen; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Humans; Infant; Male; Osteogenesis Imperfecta; Skin | 1992 |
Detection of point mutations in type I collagen by RNase digestion of RNA/RNA hybrids.
Topics: Alleles; Base Composition; Base Sequence; Cloning, Molecular; Collagen; Cyanogen Bromide; Humans; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Osteogenesis Imperfecta; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Ribonucleases; RNA; RNA, Antisense; RNA, Messenger | 1990 |
Phenotypic variability and abnormal type I collagen unstable at body temperature in a family with mild dominant osteogenesis imperfecta.
Topics: Body Temperature; Cells, Cultured; Child, Preschool; Collagen; Cyanogen Bromide; Female; Fibroblasts; Humans; Macromolecular Substances; Male; Mutation; Osteogenesis Imperfecta; Pedigree; Phenotype; Protein Conformation; Protein Denaturation | 1991 |
Altered collagen metabolism in osteogenesis imperfecta fibroblasts: a study on 33 patients with diverse forms.
Topics: Cells, Cultured; Child; Child, Preschool; Collagen; Cyanogen Bromide; Fibroblasts; Glycosylation; Humans; Infant; Osteogenesis Imperfecta; Peptide Fragments; Protein Processing, Post-Translational | 1990 |
Substitution of arginine for glycine at position 847 in the triple-helical domain of the alpha 1 (I) chain of type I collagen produces lethal osteogenesis imperfecta. Molecules that contain one or two abnormal chains differ in stability and secretion.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Cloning, Molecular; Collagen; Cyanogen Bromide; DNA; Glycine; Hot Temperature; Humans; Molecular Sequence Data; Mutation; Oligonucleotides; Osteogenesis Imperfecta; Peptide Mapping; Protein Conformation; Protein Denaturation | 1990 |
An intron mutation in the human alpha 1(I) collagen gene alters the efficiency of pre-mRNA splicing and is associated with osteogenesis imperfecta type II.
Topics: Adenine; Base Sequence; Collagen; Cyanogen Bromide; Genes; Guanine; Humans; Introns; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Osteogenesis Imperfecta; Peptide Mapping; Polymerase Chain Reaction; Reference Values; Restriction Mapping; RNA Precursors; RNA Splicing | 1990 |
Radiological "metamorphosis" in a patient with severe congenital osteogenesis imperfecta.
Topics: Collagen; Cyanogen Bromide; Female; Humans; Infant; Infant, Newborn; Male; Mutation; Osteogenesis Imperfecta; Peptide Fragments; Pregnancy; Radiography | 1990 |
Altered triple helical structure of type I procollagen in lethal perinatal osteogenesis imperfecta.
Topics: Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Female; Fibroblasts; Humans; Microbial Collagenase; Microscopy, Electron; Mutation; Osteogenesis Imperfecta; Pepsin A; Peptide Fragments; Procollagen; Protein Conformation; RNA, Messenger | 1985 |
Lethal perinatal osteogenesis imperfecta due to the substitution of arginine for glycine at residue 391 of the alpha 1(I) chain of type I collagen.
Topics: Amino Acid Sequence; Arginine; Bone and Bones; Collagen; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Female; Glycine; Humans; Hydroxylation; Infant, Newborn; Lysine; Mutation; Osteogenesis Imperfecta; Peptide Fragments; Procollagen; Trypsin | 1987 |
Type I procollagen in the severe non-lethal form of osteogenesis imperfecta. Defective pro-alpha 1(I) chains in a patient with abnormal proteoglycan metabolism and mineral deposits in the dermis.
Topics: Cells, Cultured; Child; Child, Preschool; Cyanogen Bromide; Fibroblasts; Humans; Macromolecular Substances; Male; Osteogenesis Imperfecta; Peptide Mapping; Procollagen; Proteoglycans; Reference Values; Skin | 1988 |
A structural mutation of the collagen alpha 1(I)CB7 peptide in lethal perinatal osteogenesis imperfecta.
Topics: Collagen; Cyanogen Bromide; Female; Humans; Hydroxylysine; Infant, Newborn; Isoelectric Point; Mutation; Osteogenesis Imperfecta; Peptide Fragments; Protein Conformation; Protein Processing, Post-Translational | 1987 |
Clinical variability of osteogenesis imperfecta reflecting molecular heterogeneity: cysteine substitutions in the alpha 1(I) collagen chain producing lethal and mild forms.
Topics: Adolescent; Collagen; Cyanogen Bromide; Cysteine; Genetic Variation; Humans; Male; Osteogenesis Imperfecta; Peptide Fragments; Skin | 1986 |
The molecular defect in an autosomal dominant form of osteogenesis imperfecta. Synthesis of type I procollagen containing cysteine in the triple-helical domain of pro-alpha 1(I) chains.
Topics: Chymotrypsin; Cyanogen Bromide; Cysteine; Disulfides; Fibroblasts; Genes, Dominant; Humans; Kinetics; Macromolecular Substances; Osteogenesis Imperfecta; Peptide Fragments; Procollagen; Protein Conformation; Skin; Trypsin | 1986 |