cyanidin-3-o-beta-glucopyranoside and Kidney-Failure--Chronic

Our previous research showed the antioxidant activity of anthocyanins extracted from. Acute renal injury model was initiated by 30 min clamping bilateral renal pedicle and followed by 24-hour reperfusion in C57Bl/6J mice. Four groups of mice were orally pretreated in 50 mg/g/12 h for two weeks with cyanidin-3-arabinoside, cyanidin-3-glucodise, and cyaniding-3-galactoside and anthocyanins (three-cyanidin mixture), respectively, sham-control group and the renal injury-untreated groups only with saline.. The model resulted in renal dysfunction with high serum creatinine, blood urea nitrogen, and changes in proinflammatory cytokines (TNF-ɑ, IL-1. the current study provided the first attempt to investigate the role of anthocyanins purified from

Topics: Animals; Anthocyanins; Antioxidants; Apoptosis; Arabinonucleosides; Body Weight; Caspase 9; Fruit; Galactosides; Inflammation; Kidney; Kidney Failure, Chronic; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Oxidative Stress; Photinia; Reperfusion; Reperfusion Injury; Risk