cyanates has been researched along with Anemia, Sickle Cell in 118 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 116 (98.31) | 18.7374 |
1990's | 1 (0.85) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (0.85) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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De Simone, E; Di Iorio, B; Di Micco, L; La Manna, G | 1 |
Bunn, HF | 1 |
Bolsen, B | 1 |
Bookchin, RM; Chang, H; Ewert, SM; Nagel, RL | 1 |
Aluoch, JR | 1 |
Acharya, AS; Jones, WM; Manning, JM; Sussman, LG | 1 |
Benedict, JJ; Sunberg, RJ; Van Duzee, BF | 1 |
Bessis, M; Feo, C; Jones, E; Nossal, M | 1 |
Babb, AL; Finch, CA; Lee, MY; Uvelli, DA | 1 |
Agodoa, LC; Babb, AL; Finch, CA; Lee, MY; Scribner, BH; Uvelli, DA | 1 |
Balcerzak, SP; Bishop, JN; Grever, MR; Segal, ML; Sing, DE | 1 |
Bessis, M; Feo, C; Jones, E | 1 |
Castro, O | 1 |
Benjamin, LJ; Kokkini, G; Peterson, CM | 1 |
Huicho, L; Leon-Velarde, F; Rivera-Ch, M | 1 |
Trubowitz, S | 1 |
Dyck, PJ; Ohnishi, A; Peterson, CM | 1 |
Friedman, MJ | 1 |
Brewer, GJ | 2 |
Agodoa, LC; Babb, AL; Fry, DL; Scribner, BH; Uvelli, DA | 1 |
Agodoa, LC; Babb, AL; Uvelli, DA | 1 |
Dean, J; Schechter, AN | 1 |
Chang, H; Nagel, RL | 1 |
Harkness, DR; Roth, S | 1 |
Alben, JO; Balcerzak, SP; Bare, GH; Bromberg, A; Chritakis, J | 1 |
Benson, WE; Harkness, DR; Nicholson, DH; Peterson, CM | 1 |
Cader, AM; Deiderich, DA; Gill, P; Larsen, WE; Trueworthy, RC | 1 |
Alkjaersig, N; Chaplin, H; Fletcher, A; Joist, H | 1 |
Cerami, A; Peterson, CM | 2 |
Benjamin, G; Kang, SS | 1 |
Balcerzak, SP; Bishop, J; Bromberg, PA; Flanigan, PW; Wagner, SM | 1 |
Bedine, M; Charache, S; Duffy, TP; Jander, N; Morrell, R; Scott, JC | 1 |
Itano, HA; Koenig, HM; Vedvick, TS | 1 |
Cerami, A; de Ciutiis, A; Grady, RW; Graziano, JH; Jacobs, A; Peterson, CM; Worwood, M | 1 |
Arnold, PI; Schultz, DR | 1 |
Manning, JM; Nigen, AM; Peterson, CM; White, JM | 1 |
Forte, FJ; Freedman, ML; Roseman, J | 1 |
Huisman, TH; Wong, SC | 1 |
Bemis, EL | 1 |
Adamson, JW; Detter, JC; Figley, M; Finch, CA; Hlastala, MP; Labbe, RF; Langer, EE; Stamatoyannopoulos, G | 1 |
Burka, ER; Lane, TA | 1 |
Charache, S | 2 |
Mankad, VN; Moore, RB | 1 |
Castro, O; Poillon, WN; Rana, SR | 1 |
Friedmann, I | 1 |
Beaven, GH; Bellingham, AJ; Huehns, ER; May, A | 1 |
Grossman, A; Johnson, RW | 1 |
Cerami, A; De Furia, F; Gillette, PN; Graziano, JH; Manning, JM; Miller, D; Peterson, CM | 1 |
Ben-Bassat, I; Beutler, E; Paniker, NV | 1 |
Lee, CK; Manning, JM; Nigen, AM; Njikam, N | 1 |
Eaton, JW; Kjellstrand, CM; Shideman, JR | 1 |
Huntsman, RG; Lehmann, H | 1 |
Busto, R; Cassel, J; Harkness, DR; Kim, CY; Kogure, K | 1 |
Amma, EL; Huisman, TH; Sproul, GD; Wong, S | 1 |
Cerami, A | 2 |
Schwartz, E | 1 |
Freedman, ML | 1 |
Resnick, H | 1 |
Houston, RG | 2 |
Honig, GR | 1 |
Cerami, A; De Furia, FG; Gillette, PN; Manning, JM; Miller, DR | 2 |
Cerami, A; Gillette, PN; Herbert, JT; Lu, YS; Peterson, CM | 1 |
Aponte, L; Castro, O; Finch, SC; Orlin, J; Rosen, MW | 1 |
Ranney, HM | 3 |
Cerami, A; Gillette, PN; Manning, JM; Peterson, CM | 1 |
Charache, S; Milner, PF | 1 |
Bettis, CJ; Crist, RD; Grisolia, J; Grisolia, S | 1 |
Habib, M; Schwartz, E; Watson, V | 1 |
Cerami, A; Gillette, PN; Lee, CK; Manning, JM | 1 |
Scheel, LD; Stokinger, HE | 1 |
Lee, CK; Manning, JM | 1 |
Bunn, HF; Halikas, G; Jensen, M; Kan, YW; Nathan, DG | 1 |
Fogg, J; Kilmartin, JV; Luzzana, M; Rossi-Bernardi, L | 1 |
Labbe, RF | 1 |
Gillette, PN; Jones, WM; Manning, JM; Nigen, AM; Njikam, N; Williams, RC | 1 |
Bowdon, BJ; Hammack, WJ; Wheeler, GP | 1 |
Conrad, ME; Durocher, JR; Glader, BE | 1 |
Gillette, PN; Lu, YS; Peterson, CM | 1 |
Gillette, PN; Manning, JM; Nigen, AM; Peterson, CM | 1 |
Alter, BP; Kan, YW; Nathan, DG | 2 |
Conrad, ME; Durocher, JR; Gaines, LT; Glader, BE | 1 |
Beutler, E | 1 |
Cerami, A; Gillette, PN; Lu, YS; Peterson, CM | 1 |
Bell, WR; Charache, S | 1 |
Pearson, HA | 1 |
Castro, O; Finch, SC; Orlin, J | 1 |
Finch, CA; Hlastala, MP; Papayannopoulou, T; Stamatoyannopoulos, G | 1 |
Moon, RB; Nelson, MJ; Powars, DF; Richards, JH | 1 |
Grady, R; Lu, YS; Onishi, A; Peterson, CM; Tsairis, P | 1 |
Freedman, ML; Geraghty, M; Schiffman, FJ | 1 |
Lambotte, C | 1 |
Kraus, AP; Kraus, LM | 1 |
Nalbandian, RM | 1 |
Cerami, A; De Furia, FG; Manning, JM; Miller, DR | 1 |
Diederich, D | 1 |
Beaven, GH; Huehns, ER; May, A | 1 |
Bellingham, AJ; Huehns, ER; May, A | 1 |
Bunn, HF; Feig, SA; McCaffrey, RP; Mentzer, WC; Nathan, DG; Segel, GB; Shohet, SB; Wells, R | 1 |
Carreras-Barnes, J; Diederich, DA; Grisolia, S | 1 |
Camp, FR; Nalbandian, RM; Nichols, BM; Stehouwer, EJ | 1 |
Bunn, HF; Halikas, GC; Jensen, MC; Nathan, DG | 1 |
Scott, RB | 1 |
Charache, S; Diederich, D | 1 |
Cerami, A; Gillette, PN; Manning, JM | 1 |
Cerami, A; Manning, JM | 1 |
Harris, A | 1 |
16 review(s) available for cyanates and Anemia, Sickle Cell
Article | Year |
---|---|
[Protein carbamylation: what it is and why it concerns nephrologists].
Topics: Alzheimer Disease; Amino Acids; Amyloidosis; Anemia, Sickle Cell; Animals; Cardiovascular Diseases; Cataract; Chromatography, High Pressure Liquid; Citrulline; Clinical Trials as Topic; Cyanates; Follow-Up Studies; Humans; Kidney Failure, Chronic; Lipoproteins; Protein Carbamylation; Renal Dialysis; Tandem Mass Spectrometry; tau Proteins; Urea | 2018 |
Comparative evaluation of fifteen anti-sickling agents.
Topics: Anemia, Sickle Cell; Antisickling Agents; Aspirin; Azepines; Carbamyl Phosphate; Cyanates; Cystamine; Dimethyl Adipimidate; Drug Evaluation; Erythrocyte Indices; Glyceraldehyde; Hemoglobins; Humans; Imidoesters; Mechlorethamine; Oxygen Consumption; Phenylalanine; Pyridoxal; Solubility; Urea | 1983 |
The treatment of sickle cell disease. A historical and chronological literature review of the therapies applied since 1910.
Topics: Anemia, Sickle Cell; Antisickling Agents; Azepines; Clinical Trials as Topic; Cyanates; Deamino Arginine Vasopressin; Drug Therapy, Combination; Erythrocyte Deformability; Erythrocyte Membrane; Hemoglobinometry; History, 20th Century; Humans; Piracetam; Procaine; Urea; Zinc | 1984 |
Sodium cyanate: from a promising therapeutic agent to a research tool in high altitude physiology.
Topics: Altitude; Anemia, Sickle Cell; Animals; Cyanates; Embryonic and Fetal Development; Erythropoiesis; Hemoglobins; Humans; Hypoxia; Pulmonary Ventilation | 1996 |
The management of sickle cell anemia.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Bacterial Infections; Blood Transfusion; Cholelithiasis; Cyanates; Erythrocytes, Abnormal; Exchange Transfusion, Whole Blood; Femur Head Necrosis; Hematocrit; Humans; Kidney Diseases; Leg Ulcer; Rest; Retinal Diseases; Urea | 1976 |
Clinical evaluation of cyanate in sickle cell anemia.
Topics: Administration, Oral; Anemia, Sickle Cell; Animals; Antibody Formation; Blood Proteins; Cataract; Cyanates; Humans; Nervous System; Nervous System Diseases; Oxyhemoglobins | 1975 |
A view of the current status of antisickling therapy.
Topics: Alkalies; Anemia, Sickle Cell; Antisickling Agents; Calcium; Cyanates; Dose-Response Relationship, Drug; Hemoglobin, Sickle; Urea; Zinc | 1976 |
The treatment of sickle-cell disease.
Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocytes; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Oxygen; Urea | 1972 |
Cyanate as an inhibitor of red-cell sickling.
Topics: Anemia, Sickle Cell; Animals; Body Weight; Carbamates; Carbon Isotopes; Cyanates; Dogs; Erythrocytes; Erythrocytes, Abnormal; Estrus; Female; Half-Life; Hemoglobins, Abnormal; Humans; Mice; Oxygen; Pregnancy; Rats; Urea | 1972 |
Hemoglobinopathies of clinical importance.
Topics: Anemia, Hemolytic; Anemia, Sickle Cell; Blood Transfusion; Cyanates; Cyanosis; Hemoglobin C; Hemoglobinopathies; Hemoglobins; Hemoglobins, Abnormal; Heterozygote; Humans; Infant, Newborn; Polycythemia; Splenectomy; Thalassemia; Urea | 1972 |
New drugs in the treatment of sickle cell anemia.
Topics: Anemia, Sickle Cell; Carbamates; Cyanates; Hemoglobins, Abnormal; Humans; Megestrol; Molecular Conformation; Organophosphorus Compounds; Progesterone; Testosterone; Urea | 1973 |
Sickle cell anemia and dietary precursors of cyanate.
Topics: Africa; Anemia, Sickle Cell; Cyanates; Deficiency Diseases; Diet; Ethnicity; Food Analysis; Glycosides; Humans; Nitriles; Nutritional Physiological Phenomena; Oxidation-Reduction; Plants, Edible; Thiocyanates; United States | 1973 |
Hemoglobinopathies and thalassemias. Abnormalities of hemoglobin structure, function, and synthesis.
Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Biological Transport; Blood Transfusion; Carbamates; Cyanates; Fetal Hemoglobin; Globins; Heinz Bodies; Hemoglobin C Disease; Hemoglobin, Sickle; Hemoglobinopathies; Hemoglobins, Abnormal; Oxygen; Peptides; Phosphates; Spleen; Thalassemia | 1974 |
Biochemical and physiological properties of carbamylated hemoglobin S.
Topics: Amino Acid Sequence; Anemia, Sickle Cell; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Humans; Kinetics; Microscopy, Electron; Solubility; Time Factors | 1974 |
The development of a heterologous transfusion technique: application to sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Blood Transfusion; Child; Child, Preschool; Complement Inactivator Proteins; Cyanates; Disease Models, Animal; Erythrocyte Aging; Erythrocytes; Female; Humans; Infant; Male; Mononuclear Phagocyte System; Rats; Snakes; Spleen; Transplantation, Heterologous; Venoms | 1974 |
Review of the development of cyanate as a drug in the treatment of sickle cell anemia.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Bilirubin; Binding Sites; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Chromium; Cyanates; Erythrocytes; Female; Hematocrit; Hemoglobins; Humans; L-Lactate Dehydrogenase; Male; Mice; Organ Specificity; Oxygen; Protein Binding; Time Factors; Valine | 1974 |
3 trial(s) available for cyanates and Anemia, Sickle Cell
Article | Year |
---|---|
Advances continue in sickle cell disease.
Topics: Amniocentesis; Anemia, Sickle Cell; Clinical Trials as Topic; Cyanates; DNA Restriction Enzymes; Female; Humans; Mutation; Pregnancy | 1982 |
The treatment of sickle cell disease. A historical and chronological literature review of the therapies applied since 1910.
Topics: Anemia, Sickle Cell; Antisickling Agents; Azepines; Clinical Trials as Topic; Cyanates; Deamino Arginine Vasopressin; Drug Therapy, Combination; Erythrocyte Deformability; Erythrocyte Membrane; Hemoglobinometry; History, 20th Century; Humans; Piracetam; Procaine; Urea; Zinc | 1984 |
Studies with intravenous sodium cyanate in patients with sickle cell anemia.
Topics: Adolescent; Adult; Amino Acids; Anemia, Sickle Cell; Blood Cell Count; Chromatography, Gas; Clinical Trials as Topic; Cyanates; Diuresis; Feeding and Eating Disorders; Female; Hemoglobins; Humans; Hydantoins; Injections, Intravenous; Male; Middle Aged; Reticulocytes; Thyrotropin; Time Factors; Valine; Vasopressins | 1974 |
100 other study(ies) available for cyanates and Anemia, Sickle Cell
Article | Year |
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Sickle cell disease: advances in the 1970s and challenge in the 1980s.
Topics: Anemia, Sickle Cell; Cyanates; Diet, Sodium-Restricted; Erythrocytes, Abnormal; Fetal Hemoglobin; Forecasting; Hemoglobin, Sickle; Humans; Kinetics; Microscopy, Electron; Polymers; Urea | 1982 |
Inhibition of deoxyhemoglobin S polymerization by glyceraldehyde.
Topics: Anemia, Sickle Cell; Biopolymers; Chemical Phenomena; Chemistry; Cyanates; Erythrocytes, Abnormal; Glyceraldehyde; Hemoglobin, Sickle; Humans; In Vitro Techniques; Oxygen | 1984 |
Effect of etidronate disodium on filterability of sickle cell erythrocytes.
Topics: Anemia, Sickle Cell; Cyanates; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes, Abnormal; Etidronic Acid; Filtration; Humans; In Vitro Techniques; Isoproterenol; Prostaglandins | 1980 |
Adaptation of the ektacytometer to automated continuous pO2 changes: determination of erythrocyte deformability in sickling disorders.
Topics: Anemia, Sickle Cell; Blood Viscosity; Cyanates; Erythrocytes, Abnormal; Flow Cytometry; Genetic Carrier Screening; Humans; Lasers; Oxygen | 1983 |
Effect of incubation temperature on human red cell survival.
Topics: Adult; Anemia, Sickle Cell; Carbon Radioisotopes; Chromium Radioisotopes; Cyanates; Erythrocyte Aging; Erythrocytes; Extracorporeal Circulation; Hot Temperature; Humans; Incubators; Male; Temperature; Time Factors | 1982 |
Clinical studies of a continuous extracorporeal cyanate treatment system for patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Blood Chemical Analysis; Cyanates; Erythrocytes; Female; Hematologic Tests; Hemoglobins; Humans; Male; Renal Dialysis | 1982 |
Preliminary studies of continuous extracorporeal carbamylation in the treatment of sickle cell anemia.
Topics: Adult; Anemia, Sickle Cell; Blood Gas Analysis; Cyanates; Female; Hemoglobins; Humans; Hydrogen-Ion Concentration; Male; Renal Dialysis | 1982 |
Quantitation of red cell deformability during progressive deoxygenation and oxygenation in sickling disorders (the use of an automated Ektacytometer).
Topics: Anemia, Sickle Cell; Blood Viscosity; Cyanates; Cystamine; Erythrocyte Indices; Erythrocytes, Abnormal; Heterozygote; Homozygote; Humans; Hydrogen-Ion Concentration; Oxygen; Rheology; Stress, Mechanical | 1982 |
Cryopreservation of cyanate-treated sickle erythrocytes.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Sickle Cell; Blood Preservation; Cyanates; Diphosphoglyceric Acids; Erythrocytes, Abnormal; Freezing; Hemolysis; Humans | 1982 |
Cetiedil: its potential usefulness in sickle cell disease.
Topics: Analgesics; Anemia, Sickle Cell; Animals; Azepines; Binding Sites; Cell Survival; Cyanates; Dogs; Drug Combinations; Erythrocyte Membrane; Erythrocytes, Abnormal; Filtration; Globins; Hemoglobins; Humans; Thiophenes; Vasodilator Agents | 1980 |
Axonal degeneration in sodium cyanate-induced neuropathy.
Topics: Adult; Anemia, Sickle Cell; Axons; Cyanates; Demyelinating Diseases; Female; Humans; Myelin Sheath; Nerve Fibers, Myelinated; Peripheral Nervous System Diseases; Sural Nerve | 1975 |
[Sickle cell anemia: advances in therapy].
Topics: Anemia, Sickle Cell; Cyanates; Humans; Renal Dialysis | 1978 |
Erythrocytic mechanism of sickle cell resistance to malaria.
Topics: Anemia, Sickle Cell; Cells, Cultured; Cyanates; Erythrocytes, Abnormal; Hemoglobin, Sickle; Humans; Malaria; Oxygen; Plasmodium falciparum; Sickle Cell Trait | 1978 |
Detours on the road to successful treatment of sickle cell anemia.
Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocyte Membrane; Hemoglobin, Sickle; History, 20th Century; Humans; Oxygen; Protein Binding; Research Support as Topic; Urea; Zinc | 1979 |
An extracorporeal system that modifies hemoglobin in patients with sickle cell anemia.
Topics: Anemia, Sickle Cell; Animals; Carbamates; Computers; Cyanates; Erythrocytes, Abnormal; Extracorporeal Circulation; Hemoglobins; Humans; Kinetics; Models, Biological; Models, Chemical; Sheep | 1979 |
Carbamylation distributions in extracorporeal treatment of sickle cell anemia.
Topics: Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Computers; Cyanates; Erythrocytes; Extracorporeal Circulation; Hemoglobins; Humans; Models, Biological | 1978 |
Sickle-cell anemia: molecular and cellular bases of therapeutic approaches (second of three parts).
Topics: Anemia, Sickle Cell; Animals; Cyanates; Drug Evaluation; Erythrocyte Membrane; Erythrocytes; Erythrocytes, Abnormal; Gels; Hemoglobin, Sickle; Hemoglobins; Humans; Methods; Oxygen; Rheology; Solubility; Urea | 1978 |
Measurement of sickling by controlled temperature increase.
Topics: Anemia, Sickle Cell; Cyanates; Dithionite; Heterozygote; Homozygote; Humans; Temperature; Urea | 1978 |
Mechanism of inhibition of hemoglobin S polymerization by cyanate.
Topics: Anemia, Sickle Cell; Biopolymers; Carbon Dioxide; Cyanates; Gels; Hemoglobin, Sickle; Humans; Solutions; Ultracentrifugation | 1977 |
Cyanate-induced cataracts in patients with sickle-cell hemoglobinopathies.
Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Cataract; Cyanates; Dose-Response Relationship, Drug; Humans; Lens, Crystalline; Male; Ophthalmoscopy; Remission, Spontaneous; Thalassemia; Visual Acuity | 1976 |
Hematologic and clinical responses in patients with sickle cell anemia after chronic extracorporeal red cell carbamylation.
Topics: Anemia, Sickle Cell; Carbamates; Carbamyl Phosphate; Cyanates; Erythrocyte Aging; Erythrocytes; Hemoglobins; Hemolysis; Humans; Isoflurophate; Oxygen Consumption; Pilot Projects | 1976 |
Hemostatic alterations accompanying sickle cell pain crises.
Topics: Acute Disease; Adult; Anemia, Sickle Cell; Aspirin; Blood Cell Count; Blood Platelets; Blood Transfusion; Cyanates; Dipyridamole; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Hemostasis; Humans; Male; Middle Aged; Pain | 1976 |
Cyanate and sickle-cell disease.
Topics: Anemia, Sickle Cell; Chromium Radioisotopes; Cyanates; Erythrocytes, Abnormal; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans | 1975 |
Homoserine inhibition of in vitro sickling of erythrocytes.
Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes; Gels; Hemoglobin, Sickle; Homoserine; Humans; Macromolecular Substances; Oxyhemoglobins; Urea | 1975 |
Enhancement of filterability of sickle cells by cyanate: an effect independent of oxygen saturation.
Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocytes; Filtration; Hemoglobin, Sickle; Humans; Oxygen; Urea | 1975 |
Toxic-therapeutic ratio of sodium cyanate.
Topics: Adult; Anemia, Sickle Cell; Animals; Blood Transfusion; Cyanates; Female; Humans; Male; Neural Conduction; Rats | 1975 |
Deoxyhemoglobin S: solubility vs. erythrocyte sickling.
Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes, Abnormal; Hemoglobin C Disease; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Sickle Cell Trait; Solubility; Time Factors | 1975 |
Iron metabolism, sickle cell disease, and response to cyanate.
Topics: Administration, Oral; Adolescent; Adult; Anemia, Sickle Cell; Animals; Blood Transfusion; Bone Marrow; Ceruloplasmin; Child; Cyanates; Female; Ferritins; Humans; Iron; Male; Middle Aged; Rats | 1975 |
Cyanate as an inactivator of complement proteins.
Topics: Anemia, Sickle Cell; Complement C3; Complement C5; Complement C6; Complement C7; Complement C8; Complement C9; Complement Inactivator Proteins; Complement System Proteins; Cyanates; Hemolysis; Humans; Immune Adherence Reaction; Immunoelectrophoresis, Two-Dimensional; Protein Conformation | 1975 |
Bioavailability of sodium cyanate in patients with sickle cell disease and the lack of inhibition in vitro of globin synthesis at in vivo concentrations of cyanate.
Topics: Anemia, Sickle Cell; Antacids; Biological Availability; Capsules; Cyanates; Dose-Response Relationship, Drug; Gelatin; Globins; Humans; Suppositories; Time Factors | 1975 |
Comparison of the effects of carbamyl phosphate and sodium cyanate on protein synthesis and glutathione concentration in human sickle cell and rabbit reticulocytes.
Topics: Anemia, Sickle Cell; Animals; Blood Proteins; Carbamates; Carbamyl Phosphate; Cyanates; Depression, Chemical; Erythrocytes, Abnormal; Glutathione; Humans; In Vitro Techniques; Leucine; Rabbits; Reticulocytes; Time Factors | 1975 |
Viscosity and gelation studies in deer hunting hemoglobins.
Topics: Anemia, Sickle Cell; Animals; Blood Viscosity; Cyanates; Deer; Disease Models, Animal; Gels; Hemoglobins; Hemoglobins, Abnormal; Oxyhemoglobins; Urea | 1975 |
Editorial: Optimal vs optional testing for sickle cell disease.
Topics: Anemia, Sickle Cell; Cyanates; Electrophoresis; Genetic Counseling; Humans; Mass Screening; United States; Urea | 1975 |
Extracorporeal treatment with cyanate in sickle cell disease: preliminary observations in four patients.
Topics: Adult; Anemia, Sickle Cell; Blood Transfusion, Autologous; Carbamates; Cyanates; Erythrocyte Aging; Erythrocytes; Erythropoiesis; Hemoglobin, Sickle; Humans; Iron; Oxygen; Partial Pressure; Plasma Volume; Protein Binding | 1976 |
Decreased life span and membrane damage of carbamylated erythrocytes in vitro.
Topics: Anemia, Sickle Cell; Animals; Carbamates; Carbon Radioisotopes; Cell Membrane; Cyanates; Dose-Response Relationship, Drug; Erythrocyte Aging; Erythrocytes; Globins; Glycerol; Humans; In Vitro Techniques; Rabbits; Reticulocytes | 1976 |
Advances in the understanding of sickle cell anemia.
Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Cyanates; Erythrocyte Deformability; Erythrocytes, Abnormal; Genetic Engineering; Glyceraldehyde; Hemoglobin, Sickle; Humans; Mechlorethamine; Renal Dialysis | 1986 |
Reduction in morphological sickling of red cells incubated with quinine.
Topics: Anemia, Sickle Cell; Chloroquine; Cyanates; Drug Synergism; Erythrocytes, Abnormal; Humans; Quinine | 1987 |
Autologous survival of cyanate-treated cryopreserved sickle erythrocytes.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Anemia, Sickle Cell; Blood Preservation; Cyanates; Diphosphoglyceric Acids; Erythrocyte Aging; Erythrocytes; Freezing; Humans; Oxygen | 1986 |
Treatment of sickle-cell disease.
Topics: Anemia, Sickle Cell; Cyanates; Humans | 1972 |
Effect of cyanate on sickling.
Topics: Anemia, Sickle Cell; Cell Aggregation; Chromium Isotopes; Cyanates; Diphosphoglyceric Acids; Electrophoresis, Starch Gel; Erythrocytes; Hemoglobin, Sickle; Humans; Oxygen; Oxyhemoglobins; Partial Pressure; Time Factors | 1972 |
Alteration of tyrosine aminotransferase multiple form patterns by antisickling agents and a decomposition product of antitumor agents.
Topics: Adrenal Glands; Adrenalectomy; Anemia, Sickle Cell; Animals; Carbamates; Carmustine; Cell Division; Chromatography, Ion Exchange; Cyanates; Half-Life; Isoenzymes; Liver; Male; Rats; Time Factors; Tyrosine Transaminase | 1974 |
Therapy of sickle cell disease: an approach with sodium cyanate.
Topics: Administration, Oral; Anemia, Sickle Cell; Animals; Bilirubin; Carbamates; Cyanates; Dogs; Erythrocytes; Haplorhini; Humans; Mice; Oxygen Consumption; Peptides; Rats; Sodium | 1974 |
Effect of cyanate on red blood cell sickling.
Topics: Anemia, Sickle Cell; Animals; Cell Survival; Cyanates; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Humans; Mice; Phosphofructokinase-1; Pyruvate Kinase; Reproduction; Sodium Isotopes | 1973 |
Evaluation of sickle hemoglobin and desickling agents by falling ball viscometry.
Topics: 6-Phytase; Anemia, Sickle Cell; Aspirin; Blood Viscosity; Carbamates; Cyanates; Drug Storage; Fructose; Glyceraldehyde; Glyceric Acids; Hemoglobins, Abnormal; Humans; Inositol; Methemoglobin; NAD; Phosphoric Acids; Potassium; Pyridoxal Phosphate; Time Factors; Urea; Valine; Vinblastine | 1972 |
Studies on the mechanism of action of cyanate in sickle cell disease. Oxygen affinity and gelling properties of hemoglobin S carbamylated on specific chains.
Topics: Anemia, Sickle Cell; Binding Sites; Blood Protein Electrophoresis; Carbamates; Carboxyhemoglobin; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cyanates; Electrophoresis, Polyacrylamide Gel; Gels; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Macromolecular Substances; Mercaptoethanol; Oxygen; Oxyhemoglobins; Protein Binding; Protein Conformation; Spectrophotometry; Temperature; Time Factors; Ultrafiltration | 1974 |
Continuous extracorporeal chemotherapy of blood utilizing hemodialysis: potential for the treatment of sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Blood Flow Velocity; Cyanates; Dogs; Hemoglobins; Oxygen; Renal Dialysis | 1974 |
Treatment of sickle-cell disease.
Topics: Anemia, Sickle Cell; Anesthesia; Anticoagulants; Aspirin; Bicarbonates; Blood; Blood Flow Velocity; Blood Viscosity; Body Temperature; Bone Marrow Cells; Cyanates; Female; Folic Acid; Hemoglobin, Sickle; Hemolysis; Humans; Hydrogen-Ion Concentration; Hygiene; Infarction; Kidney Concentrating Ability; Leg Ulcer; Male; Maternal Mortality; Models, Structural; Pregnancy; Pregnancy Complications, Hematologic; Thrombophlebitis; Urea | 1974 |
The effect on cerebral energy metabolites of the cyanate produced shift of the oxygen saturation curve.
Topics: Anemia, Sickle Cell; Animals; Brain; Cyanates; Energy Metabolism; Male; Oxygen; Rabbits | 1973 |
Mechanism of sickling in deer erythrocytes.
Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Animals; Cyanates; Deer; Diphosphoglyceric Acids; Genetic Variation; Goats; Hemoglobin, Sickle; Hemoglobins, Abnormal; Hydrogen-Ion Concentration; Ligands; Microscopy, Electron; Models, Molecular; Oxygen; Oxyhemoglobins; Protein Binding; Protein Conformation; Sheep; Sickle Cell Trait; Species Specificity; Urea; X-Ray Diffraction | 1974 |
Letter: Hypersusceptibility and genetic problems.
Topics: Anemia, Sickle Cell; Carbon Disulfide; Cyanates; Drug Hypersensitivity; Genetic Diseases, Inborn; Genetic Techniques; Genotype; Glucosephosphate Dehydrogenase Deficiency; Humans; Metabolism, Inborn Errors; Occupational Diseases; Occupational Health Services; Phenotype; Physical Examination; Pulmonary Emphysema; Respiratory Hypersensitivity; Trypsin Inhibitors | 1973 |
The clinical use of cyanate in sickling.
Topics: Anemia, Sickle Cell; Animals; Chemical Phenomena; Chemistry; Cyanates; Dogs; Erythrocytes; Haplorhini; Hemoglobins, Abnormal; Humans; Mice; Oxygen | 1972 |
Preliminary clinical trials with cyanate.
Topics: Anemia, Sickle Cell; Animals; Bilirubin; Carbon Isotopes; Cell Survival; Chromates; Chromium Isotopes; Cyanates; Dogs; Erythrocytes; Estrus; Female; Haplorhini; Humans; L-Lactate Dehydrogenase; Mice; Pregnancy; Rats | 1972 |
Cyanate effect on sickling.
Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes, Abnormal; Humans | 1972 |
The interactions of sickle hemoglobin.
Topics: Amino Acid Sequence; Anemia, Sickle Cell; Binding Sites; Carbamates; Cyanates; Erythrocytes, Abnormal; Gels; Hemoglobins, Abnormal; Humans; Oxidation-Reduction; Structure-Activity Relationship | 1972 |
Carbamoylation of proteins following administration to rats of carbamoyl phosphate and cyanate and effects on memory.
Topics: Anemia, Sickle Cell; Animals; Blood Proteins; Body Weight; Brain; Carbamates; Carbon Isotopes; Cyanates; Humans; Learning; Liver; Male; Memory; Mice; Models, Biological; Nerve Tissue Proteins; Protein Binding; Rats; Time Factors | 1973 |
The effect of sodium cyanate on globin synthesis.
Topics: Anemia, Sickle Cell; Cyanates; Depression, Chemical; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobins; Humans; Reticulocytes; Thalassemia | 1973 |
New treatments for sickle cell disease.
Topics: Alkalies; Anemia, Sickle Cell; Blood Transfusion; Cyanates; Humans; Urea | 1973 |
Gas chromatographic determination of the carbamylation of hemoglobin S by cyanate.
Topics: Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Chromatography, Gas; Cyanates; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Hydantoins; Methods; Time Factors; Valine | 1973 |
Hypersusceptibility and genetic problems in occupational medicine--a consensus report.
Topics: Anemia, Sickle Cell; Carbon Disulfide; Cyanates; Drug Hypersensitivity; Environmental Exposure; Genotype; Glucosephosphate Dehydrogenase Deficiency; Humans; Hypersensitivity; Latex Fixation Tests; Lung Diseases, Obstructive; Metabolism, Inborn Errors; Occupational Medicine; Peptide Hydrolases; Phenotype; Serologic Tests; Trypsin Inhibitors | 1973 |
Kinetics of the carbamylation of the amino groups of sickle cell hemoglobin by cyanate.
Topics: Anemia, Sickle Cell; Binding, Competitive; Carbamates; Carbon Dioxide; Carbon Isotopes; Carboxyhemoglobin; Countercurrent Distribution; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Hemolysis; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Oxyhemoglobins; Peptides; Potassium; Sodium; Trypsin; Valine | 1973 |
Effects of cyanate and 2,3-diphosphoglycerate on sickling. Relationship to oxygenation.
Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocytes; Glyceric Acids; Hematocrit; Hemoglobin, Sickle; Hemoglobins; Humans; Inosine; Organophosphorus Compounds; Oxygen; Oxyhemoglobins; Phosphates; Pyruvates; Sulfites; Viscosity | 1973 |
Role of the alpha-amino groups of the alpha and beta chains of human hemoglobin in oxygen-linked binding of carbon dioxide.
Topics: Anemia, Sickle Cell; Carbamates; Carbon Dioxide; Chemical Phenomena; Chemistry; Cyanates; Diphosphoglyceric Acids; Hemoglobins; Humans; Hydrogen-Ion Concentration; Ligands; Mercury; Oxygen; Oxyhemoglobins; Peptides; Potassium; Protein Binding; Structure-Activity Relationship | 1973 |
Sodium cyanate: chemical properties relevant to sickle cell disease therapy.
Topics: Anemia, Sickle Cell; Bicarbonates; Chemical Phenomena; Chemistry; Cyanates; Drug Stability; Hydrogen-Ion Concentration; Sodium; Spectrophotometry; Temperature | 1973 |
Carbamylation of the chains of hemoglobin S by cyanate in vitro and in vivo.
Topics: Amino Acids; Anemia, Sickle Cell; Carbamates; Carbon Radioisotopes; Chromatography, Ion Exchange; Cyanates; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Isoelectric Focusing; Macromolecular Substances; Oxygen; Partial Pressure; Peptides; Sodium; Structure-Activity Relationship | 1973 |
Anti-sickling activity of nitrosoureas.
Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes; Hemoglobin, Sickle; Humans; In Vitro Techniques; Nitrosourea Compounds; Time Factors | 1973 |
Effect of cyanate on erythrocyte membrane surface charge.
Topics: Anemia, Sickle Cell; Animals; Cell Membrane; Cell Movement; Cyanates; Electrophoresis; Electrophysiology; Erythrocytes; Humans; Rabbits; Rats; Surface Properties | 1973 |
The pharmacology of cyanate with a summary of its initial usage in sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Carbon Radioisotopes; Cyanates; Drug Evaluation; Endocrine Glands; Hemoglobins, Abnormal; Hemolysis; Humans; Rats | 1973 |
Determination of the blood concentrations of cyanate after intravenous administration to patients with sickle-cell disease.
Topics: Anemia, Sickle Cell; Carbamates; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography; Cyanates; Cysteine; Half-Life; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Methods; Sulfites | 1974 |
Inhibition of hemoglobin synthesis by cyanate in vitro.
Topics: Amino Acids; Anemia, Sickle Cell; Biological Transport; Bone Marrow; Carbon Radioisotopes; Cell-Free System; Cells, Cultured; Cyanates; Globins; Hemoglobins; Humans; Iontophoresis; Leucine; Lysine; Methionine; Polyribosomes; Reticulocytes; RNA, Transfer | 1974 |
Effect of cyanate on erythrocyte deformability.
Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Cyanates; Erythrocytes; Filtration; Humans; Time Factors | 1974 |
Hypothesis: changes in the O2 dissociation curve and sickling: a general formulation and therapeutic strategy.
Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Hemoglobin, Sickle; Humans; Oxygen Consumption | 1974 |
Sodium cyanate as a potential treatment for sickle-cell disease.
Topics: Administration, Oral; Adolescent; Adult; Anemia, Sickle Cell; Bilirubin; Body Weight; Carbamates; Chemical Phenomena; Chemistry; Child; Cyanates; Dose-Response Relationship, Drug; Drug Evaluation; Erythrocyte Count; Female; Gastrointestinal Diseases; Hemoglobins; Hemolysis; Humans; Male; Middle Aged; Reticulocytes; Retrospective Studies; Sodium | 1974 |
Effect of cyanate on clottability of fibrinogen.
Topics: Anemia, Sickle Cell; Blood Coagulation; Blood Coagulation Tests; Cyanates; Dialysis; Extracorporeal Circulation; Fibrinogen; Humans; Thrombin | 1974 |
Editorial: Sickle cell disease.
Topics: Anemia, Sickle Cell; Cyanates; Humans; Urea | 1974 |
The effect of hemoglobin carbamylation on the survival of human sickle cell erythrocytes in rats.
Topics: Anemia, Sickle Cell; Animals; Carbamates; Carbon Radioisotopes; Chromium Radioisotopes; Cyanates; Erythrocyte Aging; Erythrocytes; Hemoglobins; Homozygote; Humans; Male; Oxygen; Rats | 1974 |
Extracorporeal treatment of blood with cyanate in primates: physiologic and toxicologic observations.
Topics: Anemia, Sickle Cell; Animals; Blood; Carbamates; Carbon Radioisotopes; Cyanates; Erythrocytes; Erythropoiesis; Hemoglobins; Macaca; Male; Temperature; Time Factors | 1974 |
Letter: Toxicity of sodium cyanate.
Topics: Anemia, Sickle Cell; Cyanates; Humans | 1974 |
13C magnetic resonance studies of hemoglobin carbamylation.
Topics: Adult; Amino Acid Sequence; Anemia, Sickle Cell; Binding Sites; Carbon Isotopes; Carbon Monoxide; Carboxyhemoglobin; Cyanates; Evaluation Studies as Topic; Fourier Analysis; Hemoglobins; Heparin; Humans; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methods; Protein Binding; Protein Conformation; Valine | 1974 |
Sodium cyanate induced polyneuropathy in patients with sickle-cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Biopsy; Body Weight; Child; Cyanates; Electromyography; Erythrocytes; Female; Humans; Middle Aged; Nerve Fibers, Myelinated; Neural Conduction; Neuritis; Polyneuropathies; Reflex; Sural Nerve; Thermosensing; Touch | 1974 |
Studies on the mechanism of cyanate inhibition of reticulocyte protein synthesis.
Topics: Anemia, Sickle Cell; Animals; Blood Proteins; Carbon Radioisotopes; Centrifugation, Density Gradient; Cyanates; Glutathione; Humans; In Vitro Techniques; Leucine; Polyribosomes; Pronase; Rabbits; Reticulocytes; Ribosomes | 1974 |
Letter: Dietary nitriloside and sickle cell anemia in Africa.
Topics: Adult; Africa; Anemia, Sickle Cell; Child; Child, Preschool; Cyanates; Diet; Edible Grain; Glycosides; Heterozygote; Homozygote; Humans; Infant; Jamaica; Manihot; Nitriles; Thiocyanates | 1974 |
Letter: Sickle cell anemia and dietary precursors of cyanate.
Topics: Adolescent; Adult; Africa; Anemia, Sickle Cell; Black People; Child; Child, Preschool; Cyanates; Diet; Electrophoresis; Ethnicity; Hemoglobins; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Manihot; Thiocyanates; United States | 1974 |
Carbamyl phosphate mediated inhibition of the sickling of erythrocytes in vitro.
Topics: Aerobiosis; Anaerobiosis; Anemia, Sickle Cell; Carbamates; Cyanates; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Microscopy, Phase-Contrast; Oxygen; Phosphoric Acids; Potassium | 1971 |
Sickling, urea and cyanate.
Topics: Adult; Anemia, Sickle Cell; Blood Urea Nitrogen; Child; Child, Preschool; Cyanates; Humans; Urea | 1972 |
The effects of cyanate in vitro on red blood cell metabolism and function in sickle cell anemia.
Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Carbon Dioxide; Carbon Isotopes; Cyanates; Erythrocytes; Glycerophosphates; Glycolysis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Osmotic Fragility; Oxygen; Phosphates; Potassium; Pyruvates; Time Factors | 1972 |
Relationship between the oxygen affinity and in vitro sickling propensity of carbamylated sickle erythrocytes.
Topics: Anemia, Sickle Cell; Carbamates; Carbon Isotopes; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Humans; In Vitro Techniques; Oxygen; Partial Pressure; Solubility | 1972 |
The effect of carbamylation of Hb-S on the sickling process.
Topics: Anemia, Sickle Cell; Cyanates; Hemoglobins, Abnormal; Humans; In Vitro Techniques; Oxygen | 1972 |
Red cell survival of cyanate reacted sickle cells.
Topics: Anemia, Sickle Cell; Blood Viscosity; Chromium Isotopes; Cyanates; Erythrocyte Aging; Erythrocytes, Abnormal; Hemoglobins; Humans; Oxygen | 1972 |
Effects of urea and cyanate on sickling in vitro.
Topics: Anemia, Sickle Cell; Blood Urea Nitrogen; Blood Viscosity; Carbon Monoxide; Cyanates; Erythrocytes; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Oxygen; Potassium; Sodium; Urea | 1972 |
Some comparative aspects of carbamylation of human blood and of hemoglobin with cyanate and carbamyl phosphate.
Topics: Anemia, Sickle Cell; Azides; Carbamates; Carbon Isotopes; Cell Membrane; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Histones; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Magnesium | 1972 |
Urea, urease, cyanate, and the sickling of hemoglobin S.
Topics: Anaerobiosis; Anemia, Sickle Cell; Cyanates; Erythrocytes, Abnormal; Hemoglobins, Abnormal; Humans; Nitrogen; Urea; Urease | 1972 |
Sickle cell disease.
Topics: Anemia, Sickle Cell; Carbamates; Cyanates; Epidemiologic Methods; Erythrocytes; Hemoglobins, Abnormal; Humans; Injections, Intravenous; Premarital Examinations; United States; Urea | 1972 |
Reticulocyte survival in sickle cell anemia: effect of cyanate.
Topics: Anemia, Sickle Cell; Carbon Isotopes; Cell Survival; Cellulose; Chromatography; Chromium Isotopes; Cyanates; Erythrocytes; Hemoglobins; Humans; Leucine; Reticulocytes; Tritium | 1972 |
Chemical and biological aspects of the inhibition of red blood cell sickling by cyanate.
Topics: Anemia, Sickle Cell; Carbamates; Cyanates; Erythrocytes, Abnormal; Hemoglobins, Abnormal; Humans; Oxygen; Phosphates; Urea | 1972 |
Oxygen affinity independent action of cyanate and 2,3 DPG on sickling.
Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes; Glycerophosphates; Humans; Inosine; Oxygen; Phosphates; Pyruvates | 1972 |
Urea therapy in sickle-cell anemia.
Topics: Anemia, Sickle Cell; Cyanates; Heme; Hemolysis; Humans; Pain; Urea | 1971 |
Cyanate and sickling.
Topics: Anemia, Sickle Cell; Cyanates; Hemoglobins, Abnormal; Humans; Oxygen | 1971 |
Increased survival of sickle-cell erythrocytes after treatment in vitro with sodium cyanate.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Chromium Isotopes; Cyanates; Erythrocytes; Erythrocytes, Abnormal; Female; Half-Life; Hemoglobins; Humans; In Vitro Techniques; Male; Time Factors; Valine | 1971 |
Potassium cyanate as an inhibitor of the sickling of erythrocytes in vitro.
Topics: Anemia, Sickle Cell; Autoradiography; Carbamates; Carbon Isotopes; Cyanates; Erythrocytes; Erythrocytes, Abnormal; Hemoglobins; Humans; In Vitro Techniques; Microscopy, Interference; Oxygen Consumption; Potassium; Urea | 1971 |
Urea, cyanate and sickling.
Topics: Anemia, Sickle Cell; Cyanates; Hemoglobins, Abnormal; Humans; Urea | 1971 |