Page last updated: 2024-08-26

cyanates and Anemia, Sickle Cell

cyanates has been researched along with Anemia, Sickle Cell in 118 studies

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-1990116 (98.31)18.7374
1990's1 (0.85)18.2507
2000's0 (0.00)29.6817
2010's1 (0.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Simone, E; Di Iorio, B; Di Micco, L; La Manna, G1
Bunn, HF1
Bolsen, B1
Bookchin, RM; Chang, H; Ewert, SM; Nagel, RL1
Aluoch, JR1
Acharya, AS; Jones, WM; Manning, JM; Sussman, LG1
Benedict, JJ; Sunberg, RJ; Van Duzee, BF1
Bessis, M; Feo, C; Jones, E; Nossal, M1
Babb, AL; Finch, CA; Lee, MY; Uvelli, DA1
Agodoa, LC; Babb, AL; Finch, CA; Lee, MY; Scribner, BH; Uvelli, DA1
Balcerzak, SP; Bishop, JN; Grever, MR; Segal, ML; Sing, DE1
Bessis, M; Feo, C; Jones, E1
Castro, O1
Benjamin, LJ; Kokkini, G; Peterson, CM1
Huicho, L; Leon-Velarde, F; Rivera-Ch, M1
Trubowitz, S1
Dyck, PJ; Ohnishi, A; Peterson, CM1
Friedman, MJ1
Brewer, GJ2
Agodoa, LC; Babb, AL; Fry, DL; Scribner, BH; Uvelli, DA1
Agodoa, LC; Babb, AL; Uvelli, DA1
Dean, J; Schechter, AN1
Chang, H; Nagel, RL1
Harkness, DR; Roth, S1
Alben, JO; Balcerzak, SP; Bare, GH; Bromberg, A; Chritakis, J1
Benson, WE; Harkness, DR; Nicholson, DH; Peterson, CM1
Cader, AM; Deiderich, DA; Gill, P; Larsen, WE; Trueworthy, RC1
Alkjaersig, N; Chaplin, H; Fletcher, A; Joist, H1
Cerami, A; Peterson, CM2
Benjamin, G; Kang, SS1
Balcerzak, SP; Bishop, J; Bromberg, PA; Flanigan, PW; Wagner, SM1
Bedine, M; Charache, S; Duffy, TP; Jander, N; Morrell, R; Scott, JC1
Itano, HA; Koenig, HM; Vedvick, TS1
Cerami, A; de Ciutiis, A; Grady, RW; Graziano, JH; Jacobs, A; Peterson, CM; Worwood, M1
Arnold, PI; Schultz, DR1
Manning, JM; Nigen, AM; Peterson, CM; White, JM1
Forte, FJ; Freedman, ML; Roseman, J1
Huisman, TH; Wong, SC1
Bemis, EL1
Adamson, JW; Detter, JC; Figley, M; Finch, CA; Hlastala, MP; Labbe, RF; Langer, EE; Stamatoyannopoulos, G1
Burka, ER; Lane, TA1
Charache, S2
Mankad, VN; Moore, RB1
Castro, O; Poillon, WN; Rana, SR1
Friedmann, I1
Beaven, GH; Bellingham, AJ; Huehns, ER; May, A1
Grossman, A; Johnson, RW1
Cerami, A; De Furia, F; Gillette, PN; Graziano, JH; Manning, JM; Miller, D; Peterson, CM1
Ben-Bassat, I; Beutler, E; Paniker, NV1
Lee, CK; Manning, JM; Nigen, AM; Njikam, N1
Eaton, JW; Kjellstrand, CM; Shideman, JR1
Huntsman, RG; Lehmann, H1
Busto, R; Cassel, J; Harkness, DR; Kim, CY; Kogure, K1
Amma, EL; Huisman, TH; Sproul, GD; Wong, S1
Cerami, A2
Schwartz, E1
Freedman, ML1
Resnick, H1
Houston, RG2
Honig, GR1
Cerami, A; De Furia, FG; Gillette, PN; Manning, JM; Miller, DR2
Cerami, A; Gillette, PN; Herbert, JT; Lu, YS; Peterson, CM1
Aponte, L; Castro, O; Finch, SC; Orlin, J; Rosen, MW1
Ranney, HM3
Cerami, A; Gillette, PN; Manning, JM; Peterson, CM1
Charache, S; Milner, PF1
Bettis, CJ; Crist, RD; Grisolia, J; Grisolia, S1
Habib, M; Schwartz, E; Watson, V1
Cerami, A; Gillette, PN; Lee, CK; Manning, JM1
Scheel, LD; Stokinger, HE1
Lee, CK; Manning, JM1
Bunn, HF; Halikas, G; Jensen, M; Kan, YW; Nathan, DG1
Fogg, J; Kilmartin, JV; Luzzana, M; Rossi-Bernardi, L1
Labbe, RF1
Gillette, PN; Jones, WM; Manning, JM; Nigen, AM; Njikam, N; Williams, RC1
Bowdon, BJ; Hammack, WJ; Wheeler, GP1
Conrad, ME; Durocher, JR; Glader, BE1
Gillette, PN; Lu, YS; Peterson, CM1
Gillette, PN; Manning, JM; Nigen, AM; Peterson, CM1
Alter, BP; Kan, YW; Nathan, DG2
Conrad, ME; Durocher, JR; Gaines, LT; Glader, BE1
Beutler, E1
Cerami, A; Gillette, PN; Lu, YS; Peterson, CM1
Bell, WR; Charache, S1
Pearson, HA1
Castro, O; Finch, SC; Orlin, J1
Finch, CA; Hlastala, MP; Papayannopoulou, T; Stamatoyannopoulos, G1
Moon, RB; Nelson, MJ; Powars, DF; Richards, JH1
Grady, R; Lu, YS; Onishi, A; Peterson, CM; Tsairis, P1
Freedman, ML; Geraghty, M; Schiffman, FJ1
Lambotte, C1
Kraus, AP; Kraus, LM1
Nalbandian, RM1
Cerami, A; De Furia, FG; Manning, JM; Miller, DR1
Diederich, D1
Beaven, GH; Huehns, ER; May, A1
Bellingham, AJ; Huehns, ER; May, A1
Bunn, HF; Feig, SA; McCaffrey, RP; Mentzer, WC; Nathan, DG; Segel, GB; Shohet, SB; Wells, R1
Carreras-Barnes, J; Diederich, DA; Grisolia, S1
Camp, FR; Nalbandian, RM; Nichols, BM; Stehouwer, EJ1
Bunn, HF; Halikas, GC; Jensen, MC; Nathan, DG1
Scott, RB1
Charache, S; Diederich, D1
Cerami, A; Gillette, PN; Manning, JM1
Cerami, A; Manning, JM1
Harris, A1

Reviews

16 review(s) available for cyanates and Anemia, Sickle Cell

ArticleYear
[Protein carbamylation: what it is and why it concerns nephrologists].
    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2018, Volume: 35, Issue:3

    Topics: Alzheimer Disease; Amino Acids; Amyloidosis; Anemia, Sickle Cell; Animals; Cardiovascular Diseases; Cataract; Chromatography, High Pressure Liquid; Citrulline; Clinical Trials as Topic; Cyanates; Follow-Up Studies; Humans; Kidney Failure, Chronic; Lipoproteins; Protein Carbamylation; Renal Dialysis; Tandem Mass Spectrometry; tau Proteins; Urea

2018
Comparative evaluation of fifteen anti-sickling agents.
    Blood, 1983, Volume: 61, Issue:4

    Topics: Anemia, Sickle Cell; Antisickling Agents; Aspirin; Azepines; Carbamyl Phosphate; Cyanates; Cystamine; Dimethyl Adipimidate; Drug Evaluation; Erythrocyte Indices; Glyceraldehyde; Hemoglobins; Humans; Imidoesters; Mechlorethamine; Oxygen Consumption; Phenylalanine; Pyridoxal; Solubility; Urea

1983
The treatment of sickle cell disease. A historical and chronological literature review of the therapies applied since 1910.
    Tropical and geographical medicine, 1984, Volume: 36, Issue:4

    Topics: Anemia, Sickle Cell; Antisickling Agents; Azepines; Clinical Trials as Topic; Cyanates; Deamino Arginine Vasopressin; Drug Therapy, Combination; Erythrocyte Deformability; Erythrocyte Membrane; Hemoglobinometry; History, 20th Century; Humans; Piracetam; Procaine; Urea; Zinc

1984
Sodium cyanate: from a promising therapeutic agent to a research tool in high altitude physiology.
    Biological research, 1996, Volume: 29, Issue:2

    Topics: Altitude; Anemia, Sickle Cell; Animals; Cyanates; Embryonic and Fetal Development; Erythropoiesis; Hemoglobins; Humans; Hypoxia; Pulmonary Ventilation

1996
The management of sickle cell anemia.
    The Medical clinics of North America, 1976, Volume: 60, Issue:5

    Topics: Analgesics, Opioid; Anemia, Sickle Cell; Bacterial Infections; Blood Transfusion; Cholelithiasis; Cyanates; Erythrocytes, Abnormal; Exchange Transfusion, Whole Blood; Femur Head Necrosis; Hematocrit; Humans; Kidney Diseases; Leg Ulcer; Rest; Retinal Diseases; Urea

1976
Clinical evaluation of cyanate in sickle cell anemia.
    Progress in hematology, 1975, Volume: 9

    Topics: Administration, Oral; Anemia, Sickle Cell; Animals; Antibody Formation; Blood Proteins; Cataract; Cyanates; Humans; Nervous System; Nervous System Diseases; Oxyhemoglobins

1975
A view of the current status of antisickling therapy.
    American journal of hematology, 1976, Volume: 1, Issue:1

    Topics: Alkalies; Anemia, Sickle Cell; Antisickling Agents; Calcium; Cyanates; Dose-Response Relationship, Drug; Hemoglobin, Sickle; Urea; Zinc

1976
The treatment of sickle-cell disease.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocytes; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Oxygen; Urea

1972
Cyanate as an inhibitor of red-cell sickling.
    The New England journal of medicine, 1972, Oct-19, Volume: 287, Issue:16

    Topics: Anemia, Sickle Cell; Animals; Body Weight; Carbamates; Carbon Isotopes; Cyanates; Dogs; Erythrocytes; Erythrocytes, Abnormal; Estrus; Female; Half-Life; Hemoglobins, Abnormal; Humans; Mice; Oxygen; Pregnancy; Rats; Urea

1972
Hemoglobinopathies of clinical importance.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:4

    Topics: Anemia, Hemolytic; Anemia, Sickle Cell; Blood Transfusion; Cyanates; Cyanosis; Hemoglobin C; Hemoglobinopathies; Hemoglobins; Hemoglobins, Abnormal; Heterozygote; Humans; Infant, Newborn; Polycythemia; Splenectomy; Thalassemia; Urea

1972
New drugs in the treatment of sickle cell anemia.
    The American journal of the medical sciences, 1973, Volume: 265, Issue:5

    Topics: Anemia, Sickle Cell; Carbamates; Cyanates; Hemoglobins, Abnormal; Humans; Megestrol; Molecular Conformation; Organophosphorus Compounds; Progesterone; Testosterone; Urea

1973
Sickle cell anemia and dietary precursors of cyanate.
    The American journal of clinical nutrition, 1973, Volume: 26, Issue:11

    Topics: Africa; Anemia, Sickle Cell; Cyanates; Deficiency Diseases; Diet; Ethnicity; Food Analysis; Glycosides; Humans; Nitriles; Nutritional Physiological Phenomena; Oxidation-Reduction; Plants, Edible; Thiocyanates; United States

1973
Hemoglobinopathies and thalassemias. Abnormalities of hemoglobin structure, function, and synthesis.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Biological Transport; Blood Transfusion; Carbamates; Cyanates; Fetal Hemoglobin; Globins; Heinz Bodies; Hemoglobin C Disease; Hemoglobin, Sickle; Hemoglobinopathies; Hemoglobins, Abnormal; Oxygen; Peptides; Phosphates; Spleen; Thalassemia

1974
Biochemical and physiological properties of carbamylated hemoglobin S.
    Advances in enzymology and related areas of molecular biology, 1974, Volume: 40, Issue:0

    Topics: Amino Acid Sequence; Anemia, Sickle Cell; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Humans; Kinetics; Microscopy, Electron; Solubility; Time Factors

1974
The development of a heterologous transfusion technique: application to sickle cell disease.
    Connecticut medicine, 1974, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Blood Transfusion; Child; Child, Preschool; Complement Inactivator Proteins; Cyanates; Disease Models, Animal; Erythrocyte Aging; Erythrocytes; Female; Humans; Infant; Male; Mononuclear Phagocyte System; Rats; Snakes; Spleen; Transplantation, Heterologous; Venoms

1974
Review of the development of cyanate as a drug in the treatment of sickle cell anemia.
    Annals of the New York Academy of Sciences, 1974, Nov-29, Volume: 241, Issue:0

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Bilirubin; Binding Sites; Carbon Dioxide; Carbon Radioisotopes; Cell Survival; Chromium; Cyanates; Erythrocytes; Female; Hematocrit; Hemoglobins; Humans; L-Lactate Dehydrogenase; Male; Mice; Organ Specificity; Oxygen; Protein Binding; Time Factors; Valine

1974

Trials

3 trial(s) available for cyanates and Anemia, Sickle Cell

ArticleYear
Advances continue in sickle cell disease.
    JAMA, 1982, Mar-19, Volume: 247, Issue:11

    Topics: Amniocentesis; Anemia, Sickle Cell; Clinical Trials as Topic; Cyanates; DNA Restriction Enzymes; Female; Humans; Mutation; Pregnancy

1982
The treatment of sickle cell disease. A historical and chronological literature review of the therapies applied since 1910.
    Tropical and geographical medicine, 1984, Volume: 36, Issue:4

    Topics: Anemia, Sickle Cell; Antisickling Agents; Azepines; Clinical Trials as Topic; Cyanates; Deamino Arginine Vasopressin; Drug Therapy, Combination; Erythrocyte Deformability; Erythrocyte Membrane; Hemoglobinometry; History, 20th Century; Humans; Piracetam; Procaine; Urea; Zinc

1984
Studies with intravenous sodium cyanate in patients with sickle cell anemia.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Anemia, Sickle Cell; Blood Cell Count; Chromatography, Gas; Clinical Trials as Topic; Cyanates; Diuresis; Feeding and Eating Disorders; Female; Hemoglobins; Humans; Hydantoins; Injections, Intravenous; Male; Middle Aged; Reticulocytes; Thyrotropin; Time Factors; Valine; Vasopressins

1974

Other Studies

100 other study(ies) available for cyanates and Anemia, Sickle Cell

ArticleYear
Sickle cell disease: advances in the 1970s and challenge in the 1980s.
    The American journal of pediatric hematology/oncology, 1982,Summer, Volume: 4, Issue:2

    Topics: Anemia, Sickle Cell; Cyanates; Diet, Sodium-Restricted; Erythrocytes, Abnormal; Fetal Hemoglobin; Forecasting; Hemoglobin, Sickle; Humans; Kinetics; Microscopy, Electron; Polymers; Urea

1982
Inhibition of deoxyhemoglobin S polymerization by glyceraldehyde.
    Analytical biochemistry, 1984, Volume: 136, Issue:1

    Topics: Anemia, Sickle Cell; Biopolymers; Chemical Phenomena; Chemistry; Cyanates; Erythrocytes, Abnormal; Glyceraldehyde; Hemoglobin, Sickle; Humans; In Vitro Techniques; Oxygen

1984
Effect of etidronate disodium on filterability of sickle cell erythrocytes.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:5

    Topics: Anemia, Sickle Cell; Cyanates; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes, Abnormal; Etidronic Acid; Filtration; Humans; In Vitro Techniques; Isoproterenol; Prostaglandins

1980
Adaptation of the ektacytometer to automated continuous pO2 changes: determination of erythrocyte deformability in sickling disorders.
    Cytometry, 1983, Volume: 3, Issue:4

    Topics: Anemia, Sickle Cell; Blood Viscosity; Cyanates; Erythrocytes, Abnormal; Flow Cytometry; Genetic Carrier Screening; Humans; Lasers; Oxygen

1983
Effect of incubation temperature on human red cell survival.
    Artificial organs, 1982, Volume: 6, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Carbon Radioisotopes; Chromium Radioisotopes; Cyanates; Erythrocyte Aging; Erythrocytes; Extracorporeal Circulation; Hot Temperature; Humans; Incubators; Male; Temperature; Time Factors

1982
Clinical studies of a continuous extracorporeal cyanate treatment system for patients with sickle cell disease.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Blood Chemical Analysis; Cyanates; Erythrocytes; Female; Hematologic Tests; Hemoglobins; Humans; Male; Renal Dialysis

1982
Preliminary studies of continuous extracorporeal carbamylation in the treatment of sickle cell anemia.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Blood Gas Analysis; Cyanates; Female; Hemoglobins; Humans; Hydrogen-Ion Concentration; Male; Renal Dialysis

1982
Quantitation of red cell deformability during progressive deoxygenation and oxygenation in sickling disorders (the use of an automated Ektacytometer).
    Blood cells, 1982, Volume: 8, Issue:1

    Topics: Anemia, Sickle Cell; Blood Viscosity; Cyanates; Cystamine; Erythrocyte Indices; Erythrocytes, Abnormal; Heterozygote; Homozygote; Humans; Hydrogen-Ion Concentration; Oxygen; Rheology; Stress, Mechanical

1982
Cryopreservation of cyanate-treated sickle erythrocytes.
    Cryobiology, 1982, Volume: 19, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Sickle Cell; Blood Preservation; Cyanates; Diphosphoglyceric Acids; Erythrocytes, Abnormal; Freezing; Hemolysis; Humans

1982
Cetiedil: its potential usefulness in sickle cell disease.
    Blood, 1980, Volume: 55, Issue:2

    Topics: Analgesics; Anemia, Sickle Cell; Animals; Azepines; Binding Sites; Cell Survival; Cyanates; Dogs; Drug Combinations; Erythrocyte Membrane; Erythrocytes, Abnormal; Filtration; Globins; Hemoglobins; Humans; Thiophenes; Vasodilator Agents

1980
Axonal degeneration in sodium cyanate-induced neuropathy.
    Archives of neurology, 1975, Volume: 32, Issue:8

    Topics: Adult; Anemia, Sickle Cell; Axons; Cyanates; Demyelinating Diseases; Female; Humans; Myelin Sheath; Nerve Fibers, Myelinated; Peripheral Nervous System Diseases; Sural Nerve

1975
[Sickle cell anemia: advances in therapy].
    MMW, Munchener medizinische Wochenschrift, 1978, Jun-30, Volume: 120, Issue:26

    Topics: Anemia, Sickle Cell; Cyanates; Humans; Renal Dialysis

1978
Erythrocytic mechanism of sickle cell resistance to malaria.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:4

    Topics: Anemia, Sickle Cell; Cells, Cultured; Cyanates; Erythrocytes, Abnormal; Hemoglobin, Sickle; Humans; Malaria; Oxygen; Plasmodium falciparum; Sickle Cell Trait

1978
Detours on the road to successful treatment of sickle cell anemia.
    Perspectives in biology and medicine, 1979,Winter, Volume: 22, Issue:2 Pt 1

    Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocyte Membrane; Hemoglobin, Sickle; History, 20th Century; Humans; Oxygen; Protein Binding; Research Support as Topic; Urea; Zinc

1979
An extracorporeal system that modifies hemoglobin in patients with sickle cell anemia.
    Artificial organs, 1979, Volume: 3, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Carbamates; Computers; Cyanates; Erythrocytes, Abnormal; Extracorporeal Circulation; Hemoglobins; Humans; Kinetics; Models, Biological; Models, Chemical; Sheep

1979
Carbamylation distributions in extracorporeal treatment of sickle cell anemia.
    The Journal of laboratory and clinical medicine, 1978, Volume: 91, Issue:6

    Topics: Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Computers; Cyanates; Erythrocytes; Extracorporeal Circulation; Hemoglobins; Humans; Models, Biological

1978
Sickle-cell anemia: molecular and cellular bases of therapeutic approaches (second of three parts).
    The New England journal of medicine, 1978, Oct-12, Volume: 299, Issue:15

    Topics: Anemia, Sickle Cell; Animals; Cyanates; Drug Evaluation; Erythrocyte Membrane; Erythrocytes; Erythrocytes, Abnormal; Gels; Hemoglobin, Sickle; Hemoglobins; Humans; Methods; Oxygen; Rheology; Solubility; Urea

1978
Measurement of sickling by controlled temperature increase.
    Blood, 1978, Volume: 52, Issue:6

    Topics: Anemia, Sickle Cell; Cyanates; Dithionite; Heterozygote; Homozygote; Humans; Temperature; Urea

1978
Mechanism of inhibition of hemoglobin S polymerization by cyanate.
    The Journal of laboratory and clinical medicine, 1977, Volume: 89, Issue:5

    Topics: Anemia, Sickle Cell; Biopolymers; Carbon Dioxide; Cyanates; Gels; Hemoglobin, Sickle; Humans; Solutions; Ultracentrifugation

1977
Cyanate-induced cataracts in patients with sickle-cell hemoglobinopathies.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:6

    Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Cataract; Cyanates; Dose-Response Relationship, Drug; Humans; Lens, Crystalline; Male; Ophthalmoscopy; Remission, Spontaneous; Thalassemia; Visual Acuity

1976
Hematologic and clinical responses in patients with sickle cell anemia after chronic extracorporeal red cell carbamylation.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:3

    Topics: Anemia, Sickle Cell; Carbamates; Carbamyl Phosphate; Cyanates; Erythrocyte Aging; Erythrocytes; Hemoglobins; Hemolysis; Humans; Isoflurophate; Oxygen Consumption; Pilot Projects

1976
Hemostatic alterations accompanying sickle cell pain crises.
    The Journal of laboratory and clinical medicine, 1976, Volume: 88, Issue:3

    Topics: Acute Disease; Adult; Anemia, Sickle Cell; Aspirin; Blood Cell Count; Blood Platelets; Blood Transfusion; Cyanates; Dipyridamole; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Hemostasis; Humans; Male; Middle Aged; Pain

1976
Cyanate and sickle-cell disease.
    Scientific American, 1975, Volume: 232, Issue:4

    Topics: Anemia, Sickle Cell; Chromium Radioisotopes; Cyanates; Erythrocytes, Abnormal; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans

1975
Homoserine inhibition of in vitro sickling of erythrocytes.
    Experimental and molecular pathology, 1975, Volume: 22, Issue:2

    Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes; Gels; Hemoglobin, Sickle; Homoserine; Humans; Macromolecular Substances; Oxyhemoglobins; Urea

1975
Enhancement of filterability of sickle cells by cyanate: an effect independent of oxygen saturation.
    The Journal of laboratory and clinical medicine, 1975, Volume: 85, Issue:3

    Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocytes; Filtration; Hemoglobin, Sickle; Humans; Oxygen; Urea

1975
Toxic-therapeutic ratio of sodium cyanate.
    Archives of internal medicine, 1975, Volume: 135, Issue:8

    Topics: Adult; Anemia, Sickle Cell; Animals; Blood Transfusion; Cyanates; Female; Humans; Male; Neural Conduction; Rats

1975
Deoxyhemoglobin S: solubility vs. erythrocyte sickling.
    Clinical biochemistry, 1975, Volume: 8, Issue:4

    Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes, Abnormal; Hemoglobin C Disease; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Sickle Cell Trait; Solubility; Time Factors

1975
Iron metabolism, sickle cell disease, and response to cyanate.
    Blood, 1975, Volume: 46, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Anemia, Sickle Cell; Animals; Blood Transfusion; Bone Marrow; Ceruloplasmin; Child; Cyanates; Female; Ferritins; Humans; Iron; Male; Middle Aged; Rats

1975
Cyanate as an inactivator of complement proteins.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 115, Issue:6

    Topics: Anemia, Sickle Cell; Complement C3; Complement C5; Complement C6; Complement C7; Complement C8; Complement C9; Complement Inactivator Proteins; Complement System Proteins; Cyanates; Hemolysis; Humans; Immune Adherence Reaction; Immunoelectrophoresis, Two-Dimensional; Protein Conformation

1975
Bioavailability of sodium cyanate in patients with sickle cell disease and the lack of inhibition in vitro of globin synthesis at in vivo concentrations of cyanate.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Anemia, Sickle Cell; Antacids; Biological Availability; Capsules; Cyanates; Dose-Response Relationship, Drug; Gelatin; Globins; Humans; Suppositories; Time Factors

1975
Comparison of the effects of carbamyl phosphate and sodium cyanate on protein synthesis and glutathione concentration in human sickle cell and rabbit reticulocytes.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Blood Proteins; Carbamates; Carbamyl Phosphate; Cyanates; Depression, Chemical; Erythrocytes, Abnormal; Glutathione; Humans; In Vitro Techniques; Leucine; Rabbits; Reticulocytes; Time Factors

1975
Viscosity and gelation studies in deer hunting hemoglobins.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:3

    Topics: Anemia, Sickle Cell; Animals; Blood Viscosity; Cyanates; Deer; Disease Models, Animal; Gels; Hemoglobins; Hemoglobins, Abnormal; Oxyhemoglobins; Urea

1975
Editorial: Optimal vs optional testing for sickle cell disease.
    JAMA, 1975, Nov-24, Volume: 234, Issue:8

    Topics: Anemia, Sickle Cell; Cyanates; Electrophoresis; Genetic Counseling; Humans; Mass Screening; United States; Urea

1975
Extracorporeal treatment with cyanate in sickle cell disease: preliminary observations in four patients.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Blood Transfusion, Autologous; Carbamates; Cyanates; Erythrocyte Aging; Erythrocytes; Erythropoiesis; Hemoglobin, Sickle; Humans; Iron; Oxygen; Partial Pressure; Plasma Volume; Protein Binding

1976
Decreased life span and membrane damage of carbamylated erythrocytes in vitro.
    Blood, 1976, Volume: 47, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Carbamates; Carbon Radioisotopes; Cell Membrane; Cyanates; Dose-Response Relationship, Drug; Erythrocyte Aging; Erythrocytes; Globins; Glycerol; Humans; In Vitro Techniques; Rabbits; Reticulocytes

1976
Advances in the understanding of sickle cell anemia.
    Hospital practice (Office ed.), 1986, Feb-15, Volume: 21, Issue:2

    Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Cyanates; Erythrocyte Deformability; Erythrocytes, Abnormal; Genetic Engineering; Glyceraldehyde; Hemoglobin, Sickle; Humans; Mechlorethamine; Renal Dialysis

1986
Reduction in morphological sickling of red cells incubated with quinine.
    Pediatric hematology and oncology, 1987, Volume: 4, Issue:1

    Topics: Anemia, Sickle Cell; Chloroquine; Cyanates; Drug Synergism; Erythrocytes, Abnormal; Humans; Quinine

1987
Autologous survival of cyanate-treated cryopreserved sickle erythrocytes.
    American journal of hematology, 1986, Volume: 21, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Anemia, Sickle Cell; Blood Preservation; Cyanates; Diphosphoglyceric Acids; Erythrocyte Aging; Erythrocytes; Freezing; Humans; Oxygen

1986
Treatment of sickle-cell disease.
    Lancet (London, England), 1972, Dec-02, Volume: 2, Issue:7788

    Topics: Anemia, Sickle Cell; Cyanates; Humans

1972
Effect of cyanate on sickling.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Anemia, Sickle Cell; Cell Aggregation; Chromium Isotopes; Cyanates; Diphosphoglyceric Acids; Electrophoresis, Starch Gel; Erythrocytes; Hemoglobin, Sickle; Humans; Oxygen; Oxyhemoglobins; Partial Pressure; Time Factors

1972
Alteration of tyrosine aminotransferase multiple form patterns by antisickling agents and a decomposition product of antitumor agents.
    Biochemical and biophysical research communications, 1974, Aug-19, Volume: 59, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Anemia, Sickle Cell; Animals; Carbamates; Carmustine; Cell Division; Chromatography, Ion Exchange; Cyanates; Half-Life; Isoenzymes; Liver; Male; Rats; Time Factors; Tyrosine Transaminase

1974
Therapy of sickle cell disease: an approach with sodium cyanate.
    Seminars in hematology, 1974, Volume: 11, Issue:4

    Topics: Administration, Oral; Anemia, Sickle Cell; Animals; Bilirubin; Carbamates; Cyanates; Dogs; Erythrocytes; Haplorhini; Humans; Mice; Oxygen Consumption; Peptides; Rats; Sodium

1974
Effect of cyanate on red blood cell sickling.
    Federation proceedings, 1973, Volume: 32, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Cell Survival; Cyanates; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Humans; Mice; Phosphofructokinase-1; Pyruvate Kinase; Reproduction; Sodium Isotopes

1973
Evaluation of sickle hemoglobin and desickling agents by falling ball viscometry.
    The Journal of laboratory and clinical medicine, 1972, Volume: 80, Issue:2

    Topics: 6-Phytase; Anemia, Sickle Cell; Aspirin; Blood Viscosity; Carbamates; Cyanates; Drug Storage; Fructose; Glyceraldehyde; Glyceric Acids; Hemoglobins, Abnormal; Humans; Inositol; Methemoglobin; NAD; Phosphoric Acids; Potassium; Pyridoxal Phosphate; Time Factors; Urea; Valine; Vinblastine

1972
Studies on the mechanism of action of cyanate in sickle cell disease. Oxygen affinity and gelling properties of hemoglobin S carbamylated on specific chains.
    The Journal of biological chemistry, 1974, Oct-25, Volume: 249, Issue:20

    Topics: Anemia, Sickle Cell; Binding Sites; Blood Protein Electrophoresis; Carbamates; Carboxyhemoglobin; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cyanates; Electrophoresis, Polyacrylamide Gel; Gels; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Macromolecular Substances; Mercaptoethanol; Oxygen; Oxyhemoglobins; Protein Binding; Protein Conformation; Spectrophotometry; Temperature; Time Factors; Ultrafiltration

1974
Continuous extracorporeal chemotherapy of blood utilizing hemodialysis: potential for the treatment of sickle cell disease.
    Transactions - American Society for Artificial Internal Organs, 1974, Volume: 20 B

    Topics: Anemia, Sickle Cell; Animals; Blood Flow Velocity; Cyanates; Dogs; Hemoglobins; Oxygen; Renal Dialysis

1974
Treatment of sickle-cell disease.
    British journal of haematology, 1974, Volume: 28, Issue:4

    Topics: Anemia, Sickle Cell; Anesthesia; Anticoagulants; Aspirin; Bicarbonates; Blood; Blood Flow Velocity; Blood Viscosity; Body Temperature; Bone Marrow Cells; Cyanates; Female; Folic Acid; Hemoglobin, Sickle; Hemolysis; Humans; Hydrogen-Ion Concentration; Hygiene; Infarction; Kidney Concentrating Ability; Leg Ulcer; Male; Maternal Mortality; Models, Structural; Pregnancy; Pregnancy Complications, Hematologic; Thrombophlebitis; Urea

1974
The effect on cerebral energy metabolites of the cyanate produced shift of the oxygen saturation curve.
    Advances in experimental medicine and biology, 1973, Volume: 37A

    Topics: Anemia, Sickle Cell; Animals; Brain; Cyanates; Energy Metabolism; Male; Oxygen; Rabbits

1973
Mechanism of sickling in deer erythrocytes.
    Annals of the New York Academy of Sciences, 1974, Nov-29, Volume: 241, Issue:0

    Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Animals; Cyanates; Deer; Diphosphoglyceric Acids; Genetic Variation; Goats; Hemoglobin, Sickle; Hemoglobins, Abnormal; Hydrogen-Ion Concentration; Ligands; Microscopy, Electron; Models, Molecular; Oxygen; Oxyhemoglobins; Protein Binding; Protein Conformation; Sheep; Sickle Cell Trait; Species Specificity; Urea; X-Ray Diffraction

1974
Letter: Hypersusceptibility and genetic problems.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1973, Volume: 15, Issue:11

    Topics: Anemia, Sickle Cell; Carbon Disulfide; Cyanates; Drug Hypersensitivity; Genetic Diseases, Inborn; Genetic Techniques; Genotype; Glucosephosphate Dehydrogenase Deficiency; Humans; Metabolism, Inborn Errors; Occupational Diseases; Occupational Health Services; Phenotype; Physical Examination; Pulmonary Emphysema; Respiratory Hypersensitivity; Trypsin Inhibitors

1973
The clinical use of cyanate in sickling.
    The New England journal of medicine, 1972, Jul-13, Volume: 287, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Chemical Phenomena; Chemistry; Cyanates; Dogs; Erythrocytes; Haplorhini; Hemoglobins, Abnormal; Humans; Mice; Oxygen

1972
Preliminary clinical trials with cyanate.
    Advances in experimental medicine and biology, 1972, Volume: 28

    Topics: Anemia, Sickle Cell; Animals; Bilirubin; Carbon Isotopes; Cell Survival; Chromates; Chromium Isotopes; Cyanates; Dogs; Erythrocytes; Estrus; Female; Haplorhini; Humans; L-Lactate Dehydrogenase; Mice; Pregnancy; Rats

1972
Cyanate effect on sickling.
    The New England journal of medicine, 1972, Dec-28, Volume: 287, Issue:26

    Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes, Abnormal; Humans

1972
The interactions of sickle hemoglobin.
    Biochimie, 1972, Volume: 54, Issue:5

    Topics: Amino Acid Sequence; Anemia, Sickle Cell; Binding Sites; Carbamates; Cyanates; Erythrocytes, Abnormal; Gels; Hemoglobins, Abnormal; Humans; Oxidation-Reduction; Structure-Activity Relationship

1972
Carbamoylation of proteins following administration to rats of carbamoyl phosphate and cyanate and effects on memory.
    European journal of biochemistry, 1973, Jan-03, Volume: 32, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Blood Proteins; Body Weight; Brain; Carbamates; Carbon Isotopes; Cyanates; Humans; Learning; Liver; Male; Memory; Mice; Models, Biological; Nerve Tissue Proteins; Protein Binding; Rats; Time Factors

1973
The effect of sodium cyanate on globin synthesis.
    Blood, 1973, Volume: 41, Issue:5

    Topics: Anemia, Sickle Cell; Cyanates; Depression, Chemical; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobins; Humans; Reticulocytes; Thalassemia

1973
New treatments for sickle cell disease.
    The Medical letter on drugs and therapeutics, 1973, Feb-16, Volume: 15, Issue:4

    Topics: Alkalies; Anemia, Sickle Cell; Blood Transfusion; Cyanates; Humans; Urea

1973
Gas chromatographic determination of the carbamylation of hemoglobin S by cyanate.
    The Journal of laboratory and clinical medicine, 1973, Volume: 81, Issue:6

    Topics: Anemia, Sickle Cell; Chemical Phenomena; Chemistry; Chromatography, Gas; Cyanates; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Hydantoins; Methods; Time Factors; Valine

1973
Hypersusceptibility and genetic problems in occupational medicine--a consensus report.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1973, Volume: 15, Issue:7

    Topics: Anemia, Sickle Cell; Carbon Disulfide; Cyanates; Drug Hypersensitivity; Environmental Exposure; Genotype; Glucosephosphate Dehydrogenase Deficiency; Humans; Hypersensitivity; Latex Fixation Tests; Lung Diseases, Obstructive; Metabolism, Inborn Errors; Occupational Medicine; Peptide Hydrolases; Phenotype; Serologic Tests; Trypsin Inhibitors

1973
Kinetics of the carbamylation of the amino groups of sickle cell hemoglobin by cyanate.
    The Journal of biological chemistry, 1973, Aug-25, Volume: 248, Issue:16

    Topics: Anemia, Sickle Cell; Binding, Competitive; Carbamates; Carbon Dioxide; Carbon Isotopes; Carboxyhemoglobin; Countercurrent Distribution; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Hemolysis; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Oxyhemoglobins; Peptides; Potassium; Sodium; Trypsin; Valine

1973
Effects of cyanate and 2,3-diphosphoglycerate on sickling. Relationship to oxygenation.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:10

    Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Erythrocytes; Glyceric Acids; Hematocrit; Hemoglobin, Sickle; Hemoglobins; Humans; Inosine; Organophosphorus Compounds; Oxygen; Oxyhemoglobins; Phosphates; Pyruvates; Sulfites; Viscosity

1973
Role of the alpha-amino groups of the alpha and beta chains of human hemoglobin in oxygen-linked binding of carbon dioxide.
    The Journal of biological chemistry, 1973, Oct-25, Volume: 248, Issue:20

    Topics: Anemia, Sickle Cell; Carbamates; Carbon Dioxide; Chemical Phenomena; Chemistry; Cyanates; Diphosphoglyceric Acids; Hemoglobins; Humans; Hydrogen-Ion Concentration; Ligands; Mercury; Oxygen; Oxyhemoglobins; Peptides; Potassium; Protein Binding; Structure-Activity Relationship

1973
Sodium cyanate: chemical properties relevant to sickle cell disease therapy.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:10

    Topics: Anemia, Sickle Cell; Bicarbonates; Chemical Phenomena; Chemistry; Cyanates; Drug Stability; Hydrogen-Ion Concentration; Sodium; Spectrophotometry; Temperature

1973
Carbamylation of the chains of hemoglobin S by cyanate in vitro and in vivo.
    The Journal of biological chemistry, 1973, Dec-10, Volume: 248, Issue:23

    Topics: Amino Acids; Anemia, Sickle Cell; Carbamates; Carbon Radioisotopes; Chromatography, Ion Exchange; Cyanates; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Isoelectric Focusing; Macromolecular Substances; Oxygen; Partial Pressure; Peptides; Sodium; Structure-Activity Relationship

1973
Anti-sickling activity of nitrosoureas.
    Biochemical and biophysical research communications, 1973, Oct-01, Volume: 54, Issue:3

    Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes; Hemoglobin, Sickle; Humans; In Vitro Techniques; Nitrosourea Compounds; Time Factors

1973
Effect of cyanate on erythrocyte membrane surface charge.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Oct-01, Volume: 144, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Cell Membrane; Cell Movement; Cyanates; Electrophoresis; Electrophysiology; Erythrocytes; Humans; Rabbits; Rats; Surface Properties

1973
The pharmacology of cyanate with a summary of its initial usage in sickle cell disease.
    Progress in hematology, 1973, Volume: 8

    Topics: Anemia, Sickle Cell; Animals; Carbon Radioisotopes; Cyanates; Drug Evaluation; Endocrine Glands; Hemoglobins, Abnormal; Hemolysis; Humans; Rats

1973
Determination of the blood concentrations of cyanate after intravenous administration to patients with sickle-cell disease.
    The Journal of laboratory and clinical medicine, 1974, Volume: 83, Issue:1

    Topics: Anemia, Sickle Cell; Carbamates; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography; Cyanates; Cysteine; Half-Life; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Methods; Sulfites

1974
Inhibition of hemoglobin synthesis by cyanate in vitro.
    Blood, 1974, Volume: 43, Issue:1

    Topics: Amino Acids; Anemia, Sickle Cell; Biological Transport; Bone Marrow; Carbon Radioisotopes; Cell-Free System; Cells, Cultured; Cyanates; Globins; Hemoglobins; Humans; Iontophoresis; Leucine; Lysine; Methionine; Polyribosomes; Reticulocytes; RNA, Transfer

1974
Effect of cyanate on erythrocyte deformability.
    Blood, 1974, Volume: 43, Issue:2

    Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Cyanates; Erythrocytes; Filtration; Humans; Time Factors

1974
Hypothesis: changes in the O2 dissociation curve and sickling: a general formulation and therapeutic strategy.
    Blood, 1974, Volume: 43, Issue:2

    Topics: Anemia, Sickle Cell; Cyanates; Diphosphoglyceric Acids; Hemoglobin, Sickle; Humans; Oxygen Consumption

1974
Sodium cyanate as a potential treatment for sickle-cell disease.
    The New England journal of medicine, 1974, Mar-21, Volume: 290, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Anemia, Sickle Cell; Bilirubin; Body Weight; Carbamates; Chemical Phenomena; Chemistry; Child; Cyanates; Dose-Response Relationship, Drug; Drug Evaluation; Erythrocyte Count; Female; Gastrointestinal Diseases; Hemoglobins; Hemolysis; Humans; Male; Middle Aged; Reticulocytes; Retrospective Studies; Sodium

1974
Effect of cyanate on clottability of fibrinogen.
    The Journal of laboratory and clinical medicine, 1974, Volume: 83, Issue:5

    Topics: Anemia, Sickle Cell; Blood Coagulation; Blood Coagulation Tests; Cyanates; Dialysis; Extracorporeal Circulation; Fibrinogen; Humans; Thrombin

1974
Editorial: Sickle cell disease.
    The Yale journal of biology and medicine, 1974, Volume: 47, Issue:1

    Topics: Anemia, Sickle Cell; Cyanates; Humans; Urea

1974
The effect of hemoglobin carbamylation on the survival of human sickle cell erythrocytes in rats.
    The Yale journal of biology and medicine, 1974, Volume: 47, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Carbamates; Carbon Radioisotopes; Chromium Radioisotopes; Cyanates; Erythrocyte Aging; Erythrocytes; Hemoglobins; Homozygote; Humans; Male; Oxygen; Rats

1974
Extracorporeal treatment of blood with cyanate in primates: physiologic and toxicologic observations.
    The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Blood; Carbamates; Carbon Radioisotopes; Cyanates; Erythrocytes; Erythropoiesis; Hemoglobins; Macaca; Male; Temperature; Time Factors

1974
Letter: Toxicity of sodium cyanate.
    The New England journal of medicine, 1974, Jul-25, Volume: 291, Issue:4

    Topics: Anemia, Sickle Cell; Cyanates; Humans

1974
13C magnetic resonance studies of hemoglobin carbamylation.
    Physiological chemistry and physics, 1974, Volume: 6, Issue:1

    Topics: Adult; Amino Acid Sequence; Anemia, Sickle Cell; Binding Sites; Carbon Isotopes; Carbon Monoxide; Carboxyhemoglobin; Cyanates; Evaluation Studies as Topic; Fourier Analysis; Hemoglobins; Heparin; Humans; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methods; Protein Binding; Protein Conformation; Valine

1974
Sodium cyanate induced polyneuropathy in patients with sickle-cell disease.
    Annals of internal medicine, 1974, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Biopsy; Body Weight; Child; Cyanates; Electromyography; Erythrocytes; Female; Humans; Middle Aged; Nerve Fibers, Myelinated; Neural Conduction; Neuritis; Polyneuropathies; Reflex; Sural Nerve; Thermosensing; Touch

1974
Studies on the mechanism of cyanate inhibition of reticulocyte protein synthesis.
    British journal of haematology, 1974, Volume: 27, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Blood Proteins; Carbon Radioisotopes; Centrifugation, Density Gradient; Cyanates; Glutathione; Humans; In Vitro Techniques; Leucine; Polyribosomes; Pronase; Rabbits; Reticulocytes; Ribosomes

1974
Letter: Dietary nitriloside and sickle cell anemia in Africa.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:8

    Topics: Adult; Africa; Anemia, Sickle Cell; Child; Child, Preschool; Cyanates; Diet; Edible Grain; Glycosides; Heterozygote; Homozygote; Humans; Infant; Jamaica; Manihot; Nitriles; Thiocyanates

1974
Letter: Sickle cell anemia and dietary precursors of cyanate.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Africa; Anemia, Sickle Cell; Black People; Child; Child, Preschool; Cyanates; Diet; Electrophoresis; Ethnicity; Hemoglobins; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Manihot; Thiocyanates; United States

1974
Carbamyl phosphate mediated inhibition of the sickling of erythrocytes in vitro.
    Biochemical and biophysical research communications, 1971, Sep-17, Volume: 44, Issue:6

    Topics: Aerobiosis; Anaerobiosis; Anemia, Sickle Cell; Carbamates; Cyanates; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Microscopy, Phase-Contrast; Oxygen; Phosphoric Acids; Potassium

1971
Sickling, urea and cyanate.
    The New England journal of medicine, 1972, Feb-17, Volume: 286, Issue:7

    Topics: Adult; Anemia, Sickle Cell; Blood Urea Nitrogen; Child; Child, Preschool; Cyanates; Humans; Urea

1972
The effects of cyanate in vitro on red blood cell metabolism and function in sickle cell anemia.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:3

    Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Carbon Dioxide; Carbon Isotopes; Cyanates; Erythrocytes; Glycerophosphates; Glycolysis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine; Osmotic Fragility; Oxygen; Phosphates; Potassium; Pyruvates; Time Factors

1972
Relationship between the oxygen affinity and in vitro sickling propensity of carbamylated sickle erythrocytes.
    Biochemical and biophysical research communications, 1972, Feb-16, Volume: 46, Issue:3

    Topics: Anemia, Sickle Cell; Carbamates; Carbon Isotopes; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Humans; In Vitro Techniques; Oxygen; Partial Pressure; Solubility

1972
The effect of carbamylation of Hb-S on the sickling process.
    Clinical science, 1972, Volume: 42, Issue:4

    Topics: Anemia, Sickle Cell; Cyanates; Hemoglobins, Abnormal; Humans; In Vitro Techniques; Oxygen

1972
Red cell survival of cyanate reacted sickle cells.
    Clinical science, 1972, Volume: 42, Issue:4

    Topics: Anemia, Sickle Cell; Blood Viscosity; Chromium Isotopes; Cyanates; Erythrocyte Aging; Erythrocytes, Abnormal; Hemoglobins; Humans; Oxygen

1972
Effects of urea and cyanate on sickling in vitro.
    The New England journal of medicine, 1972, Jul-13, Volume: 287, Issue:2

    Topics: Anemia, Sickle Cell; Blood Urea Nitrogen; Blood Viscosity; Carbon Monoxide; Cyanates; Erythrocytes; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Oxygen; Potassium; Sodium; Urea

1972
Some comparative aspects of carbamylation of human blood and of hemoglobin with cyanate and carbamyl phosphate.
    European journal of biochemistry, 1972, Volume: 27, Issue:1

    Topics: Anemia, Sickle Cell; Azides; Carbamates; Carbon Isotopes; Cell Membrane; Cyanates; Erythrocytes; Hemoglobins; Hemoglobins, Abnormal; Histones; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Magnesium

1972
Urea, urease, cyanate, and the sickling of hemoglobin S.
    Clinical chemistry, 1972, Volume: 18, Issue:9

    Topics: Anaerobiosis; Anemia, Sickle Cell; Cyanates; Erythrocytes, Abnormal; Hemoglobins, Abnormal; Humans; Nitrogen; Urea; Urease

1972
Sickle cell disease.
    Blood, 1972, Volume: 39, Issue:3

    Topics: Anemia, Sickle Cell; Carbamates; Cyanates; Epidemiologic Methods; Erythrocytes; Hemoglobins, Abnormal; Humans; Injections, Intravenous; Premarital Examinations; United States; Urea

1972
Reticulocyte survival in sickle cell anemia: effect of cyanate.
    Blood, 1972, Volume: 40, Issue:5

    Topics: Anemia, Sickle Cell; Carbon Isotopes; Cell Survival; Cellulose; Chromatography; Chromium Isotopes; Cyanates; Erythrocytes; Hemoglobins; Humans; Leucine; Reticulocytes; Tritium

1972
Chemical and biological aspects of the inhibition of red blood cell sickling by cyanate.
    Advances in experimental medicine and biology, 1972, Volume: 28

    Topics: Anemia, Sickle Cell; Carbamates; Cyanates; Erythrocytes, Abnormal; Hemoglobins, Abnormal; Humans; Oxygen; Phosphates; Urea

1972
Oxygen affinity independent action of cyanate and 2,3 DPG on sickling.
    Advances in experimental medicine and biology, 1972, Volume: 28

    Topics: Anemia, Sickle Cell; Cyanates; Erythrocytes; Glycerophosphates; Humans; Inosine; Oxygen; Phosphates; Pyruvates

1972
Urea therapy in sickle-cell anemia.
    The New England journal of medicine, 1971, Oct-28, Volume: 285, Issue:18

    Topics: Anemia, Sickle Cell; Cyanates; Heme; Hemolysis; Humans; Pain; Urea

1971
Cyanate and sickling.
    The New England journal of medicine, 1971, 11-11, Volume: 285, Issue:20

    Topics: Anemia, Sickle Cell; Cyanates; Hemoglobins, Abnormal; Humans; Oxygen

1971
Increased survival of sickle-cell erythrocytes after treatment in vitro with sodium cyanate.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:11

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Chromium Isotopes; Cyanates; Erythrocytes; Erythrocytes, Abnormal; Female; Half-Life; Hemoglobins; Humans; In Vitro Techniques; Male; Time Factors; Valine

1971
Potassium cyanate as an inhibitor of the sickling of erythrocytes in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:6

    Topics: Anemia, Sickle Cell; Autoradiography; Carbamates; Carbon Isotopes; Cyanates; Erythrocytes; Erythrocytes, Abnormal; Hemoglobins; Humans; In Vitro Techniques; Microscopy, Interference; Oxygen Consumption; Potassium; Urea

1971
Urea, cyanate and sickling.
    The New England journal of medicine, 1971, 09-16, Volume: 285, Issue:12

    Topics: Anemia, Sickle Cell; Cyanates; Hemoglobins, Abnormal; Humans; Urea

1971