Page last updated: 2024-10-16

curdlan and Ileitis

curdlan has been researched along with Ileitis in 3 studies

D-hexose : A hexose that has D-configuration at position 5.

Ileitis: Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.

Research Excerpts

ExcerptRelevanceReference
"In curdlan-treated SKG mice, arthritis, enthesitis, and ileitis were IL-23 dependent."3.80Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice. ( Baillet, AC; Benham, H; Brown, MA; Hasnain, SZ; Kikly, K; McGuckin, MA; Rehaume, LM; Ruutu, M; Strutton, G; Thomas, GP; Thomas, R; Tseng, HW; Velasco, J; Wang, R, 2014)
"After systemic injection of curdlan, SKG mice developed enthesitis, wrist, ankle, and sacroiliac joint arthritis, dactylitis, plantar fasciitis, vertebral inflammation, ileitis resembling Crohn's disease, and unilateral uveitis."3.78β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. ( Alexander, K; Benham, H; Brown, MA; Davies, J; Degli-Esposti, MA; Kikly, K; McGuckin, MA; Pettit, AR; Rehaume, L; Ruutu, M; Steck, R; Strutton, G; Thomas, G; Thomas, R; Tran, A; Velasco, J; Wilson, RJ; Zinkernagel, MS, 2012)
"Stat-3p inhibition is a promising treatment for both inflammation and new bone formation in AS."1.62STAT3 phosphorylation inhibition for treating inflammation and new bone formation in ankylosing spondylitis. ( Choi, SH; Choi, YD; Jin, SH; Jo, S; Kim, J; Kim, JY; Kim, MJ; Kim, TH; Kim, TJ; Lee, YJ; Park, PR; Park, YS; Shim, SC; Song, HC; Won, EJ, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jo, S1
Won, EJ1
Kim, MJ1
Lee, YJ1
Jin, SH1
Park, PR1
Song, HC1
Kim, J1
Choi, YD1
Kim, JY1
Shim, SC1
Choi, SH1
Park, YS1
Kim, TH1
Kim, TJ1
Benham, H2
Rehaume, LM1
Hasnain, SZ1
Velasco, J2
Baillet, AC1
Ruutu, M2
Kikly, K2
Wang, R1
Tseng, HW1
Thomas, GP1
Brown, MA2
Strutton, G2
McGuckin, MA2
Thomas, R2
Thomas, G1
Steck, R1
Degli-Esposti, MA1
Zinkernagel, MS1
Alexander, K1
Tran, A1
Rehaume, L1
Wilson, RJ1
Davies, J1
Pettit, AR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Terbinafine Treatment of Axial Spondyloarthropathy[NCT05119712]Early Phase 10 participants (Actual)Interventional2021-03-09Withdrawn (stopped due to Study stopped due to poor recruitment.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for curdlan and Ileitis

ArticleYear
STAT3 phosphorylation inhibition for treating inflammation and new bone formation in ankylosing spondylitis.
    Rheumatology (Oxford, England), 2021, 08-02, Volume: 60, Issue:8

    Topics: Adult; Animals; beta-Glucans; Cell Differentiation; Disease Models, Animal; Female; Humans; Ileitis;

2021
Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:7

    Topics: Animals; Antibodies; beta-Glucans; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Ile

2014
β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:7

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Autoim

2012