Page last updated: 2024-10-16

curdlan and Arthritis, Spinal

curdlan has been researched along with Arthritis, Spinal in 6 studies

D-hexose : A hexose that has D-configuration at position 5.

Research Excerpts

ExcerptRelevanceReference
"In curdlan-treated SKG mice, arthritis, enthesitis, and ileitis were IL-23 dependent."3.80Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice. ( Baillet, AC; Benham, H; Brown, MA; Hasnain, SZ; Kikly, K; McGuckin, MA; Rehaume, LM; Ruutu, M; Strutton, G; Thomas, GP; Thomas, R; Tseng, HW; Velasco, J; Wang, R, 2014)
"After systemic injection of curdlan, SKG mice developed enthesitis, wrist, ankle, and sacroiliac joint arthritis, dactylitis, plantar fasciitis, vertebral inflammation, ileitis resembling Crohn's disease, and unilateral uveitis."3.78β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice. ( Alexander, K; Benham, H; Brown, MA; Davies, J; Degli-Esposti, MA; Kikly, K; McGuckin, MA; Pettit, AR; Rehaume, L; Ruutu, M; Steck, R; Strutton, G; Thomas, G; Thomas, R; Tran, A; Velasco, J; Wilson, RJ; Zinkernagel, MS, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Min, HK2
Choi, J1
Lee, SY2
Lee, AR1
Min, BM1
Cho, ML2
Park, SH2
Swann, JW1
Koneva, LA1
Regan-Komito, D1
Sansom, SN1
Powrie, F1
Griseri, T1
Rehaume, LM2
Matigian, N1
Mehdi, AM1
Lachner, N1
Bowerman, KL1
Daly, J1
Lê Cao, KA1
Hugenholtz, P1
Thomas, R3
Benham, H2
Hasnain, SZ1
Velasco, J2
Baillet, AC1
Ruutu, M2
Kikly, K2
Wang, R1
Tseng, HW1
Thomas, GP1
Brown, MA2
Strutton, G2
McGuckin, MA2
Kim, JK1
Kim, EK1
Lee, SH1
Lee, J1
Kwok, SK1
Thomas, G1
Steck, R1
Degli-Esposti, MA1
Zinkernagel, MS1
Alexander, K1
Tran, A1
Rehaume, L1
Wilson, RJ1
Davies, J1
Pettit, AR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Terbinafine Treatment of Axial Spondyloarthropathy[NCT05119712]Early Phase 10 participants (Actual)Interventional2021-03-09Withdrawn (stopped due to Study stopped due to poor recruitment.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for curdlan and Arthritis, Spinal

ArticleYear
Vitronectin-derived bioactive peptide prevents spondyloarthritis by modulating Th17/Treg imbalance in mice with curdlan-induced spondyloarthritis.
    PloS one, 2022, Volume: 17, Issue:1

    Topics: Animals; beta-Glucans; Celecoxib; Cytokines; Disease Models, Animal; Disease Progression; Female; Ge

2022
IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors.
    The Journal of experimental medicine, 2020, 09-07, Volume: 217, Issue:9

    Topics: Anemia; Animals; Annexin A5; beta-Glucans; Bone Marrow; Cell Differentiation; Chronic Disease; Eryth

2020
IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota.
    Annals of the rheumatic diseases, 2019, Volume: 78, Issue:4

    Topics: Animals; Bacteria; beta-Glucans; Dysbiosis; Feces; Female; Gastrointestinal Microbiome; Homeostasis;

2019
Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:7

    Topics: Animals; Antibodies; beta-Glucans; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Ile

2014
Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis.
    Journal of translational medicine, 2016, 06-27, Volume: 14, Issue:1

    Topics: Alanine; Animals; Arthritis, Experimental; beta-Glucans; Cytokines; Inflammation; Inflammation Media

2016
β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:7

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Autoim

2012