curcumin has been researched along with Leukemia--Myelomonocytic--Acute* in 1 studies
1 other study(ies) available for curcumin and Leukemia--Myelomonocytic--Acute
Article | Year |
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[Effect of curcumin on the proliferation of murine CFU-GM and WEHI-3B cells].
To evaluate the effect of curcumin on the proliferation of hematopoietic progenitor cells or leukemic stem cells.. Mouse bone marrow cells (colony forming unit-granulocyte and macrophage, CFU-GM) and WEHI-3B cells were observed using the colony assays.. The curcumin significantly inhibited the proliferation of both CFU-GM and WEHI-3B cells in a dose-dependent manner ranging from 10(-8) to 10(-4) mol.L-1; their IC50S were 1.036 x 10(-5) mol.L-1 and 1.220 x 10(-6) mol.L-1 of curcumin respectively.. The proliferation of murine CFU-GM and WEHI-3B cells can be suppressed by curcumin. The inhibitory effect of curcumin on the proliferation of WEHI-3B cells is stronger than that of CFU-GM. Topics: Animals; Antineoplastic Agents; Cell Division; Cells, Cultured; Curcumin; DNA; Hematopoietic Stem Cells; Leukemia, Myelomonocytic, Acute; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured | 2000 |