curcumin and Celiac-Disease

Nutrition and food items may improve or worsen symptoms in Crohn's disease and ulcerative colitis. Protein malnutrition and vitamin and mineral deficiencies are common, particularly deficiency of iron and vitamin D. Dietary fibres and omega-3 fatty acids are safe, but no evidence supports their use as treatment. The use of probiotics is not encouraged in patients with Crohn's disease, but it may maintain remission in ulcerative colitis. Curcumin, chamomile, and other herbal extracts are promising in the treatment of mild ulcerative colitis, but validation of products and monitoring of side effects are insufficient.

Topics: Celiac Disease; Chamomile; Curcuma; Diet; Dietary Fiber; Dietary Supplements; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Humans; Inflammatory Bowel Diseases; Lactose Intolerance; Micronutrients; Nutritional Status; Vitamin D

Wheat is a major diet from many years; apart from its nutritious value, the wheat protein gliadin is responsible for many inflammatory diseases like celiac disease (CD), and non-celiac gluten sensitivity (NCGS). In this study, the gliadin-induced inflammation and associated cellular damage along with the protective role of curcumin was evaluated using human intestinal cell lines (HCT-116 and HT-29) as a model. Cells were cultured and exposed to 160 μg/ml of gliadin, 100 μM H

Topics: Anti-Inflammatory Agents; Celiac Disease; Curcumin; Cytokines; Enteritis; Gliadin; HCT116 Cells; HT29 Cells; Humans; Inflammation Mediators; Integrin alpha Chains; Integrin beta Chains; Intestinal Mucosa; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Oxidative Stress; Signal Transduction; Wheat Hypersensitivity