cuprizone has been researched along with Innate Inflammatory Response in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (8.33) | 29.6817 |
| 2010's | 20 (41.67) | 24.3611 |
| 2020's | 24 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anyaegbu, C; Bartlett, CA; Fitzgerald, M; Hellewell, SC; Lins, B; McGonigle, T; Papini, M; Toomey, LM; Warnock, A; Wright, AJ | 1 |
| Khalili, M; Kiasalari, Z; Pourmohammadi, S; Roghani, M | 1 |
| Almolda, B; Castellano, B; Enrich-Bengoa, J; González, B; Manich, G; Perálvarez-Marín, A; Sanchez-Molina, P; Saura, J; Solà, C; Valente, T | 1 |
| Crocker, SJ; Hardy, CC; Ramasamy, R; Smith, PP | 1 |
| Bakhtiari, N; Hojati, V; Honarvar, F; Javan, M; Zare, L | 1 |
| Ibrahim Fouad, G | 1 |
| ELBini, I; Neili, NE | 1 |
| A Abd-Elmawla, M; A Ahmed, K; Abdelmonem, M; Gad, ES; Ghaiad, HR | 1 |
| Kim, KW; Ljunggren-Rose, Å; Matta, P; Sriram, S; Toki, S | 1 |
| Al-Sharabi, N; Bø, L; Costea, DE; Fromreide, S; Kråkenes, T; Kvistad, CE; Mohamed-Ahmed, S; Mustafa, K; Wergeland, S | 1 |
| Beyer, C; Clarner, T; Fragoulis, A; Nellessen, A; Nyamoya, S; Slowik, A; Wruck, C; Zendedel, A | 1 |
| Bao, XQ; Liu, H; Zhang, D; Zhang, Z; Zhao, Z | 1 |
| Cheli, VT; Paez, PM; Santiago González, DA; Wan, R; Zamora, NN | 1 |
| Abdel-Maged, AE; Awad, AS; Azab, SS; Gad, AM; Mohamed, EA; Rashed, LA | 1 |
| Calzado, MA; Feliú, A; García-Martin, A; Garrido-Rodríguez, M; Guaza, C; Mestre, L; Muñoz, E; Navarrete, C | 1 |
| Branton, WG; Doan, MAL; Fernandes, JP; Major, EO; Monaco, MC; Power, C; Saito, LB; Schmitt, LM; Smith, MJ; Wuest, F; Wuest, M | 1 |
| Amor, S; Greiner, T; Joost, S; Kipp, M; Rohr, SO; Schmitz, C; Valk, PV | 1 |
| Abouhamzeh, B; Fattahi, N; Khalilian, B; Madadi, S | 1 |
| Abdoulkader, N; Aigrot, MS; Baron-Van Evercooren, A; Branzoli, F; Genovese, G; Langui, D; Lehericy, S; Ligneul, C; Millecamps, A; Palombo, M; Petiet, A; Santin, MD; Stankoff, B; Valette, J | 1 |
| Baumlin, N; Farine, H; Marrie, J; Martinic, MM; Mentzel, U; Pouzol, L; Sassi, A; Tunis, M; Vezzali, E | 1 |
| Chan, JR; Chen, Y; Kunjamma, RB; Popko, B; Weiner, M | 1 |
| Elmieh, A; Sajedi, D; Shabani, R | 1 |
| Brousse, B; Cayre, M; Daian, F; Durbec, P; Magalon, K; Mercier, O | 1 |
| Bassani, C; Bedogni, F; Colombo, E; Comi, G; Di Dario, M; Dina, G; Farina, C; Fermo, I; Fredrickx, E; Martinelli, V; Newcombe, J; Quattrini, A; Taveggia, C; Triolo, D | 1 |
| Brickey, WJ; David, CN; Freeman, L; Guo, H; Jha, S; Ting, JP | 1 |
| Bando, Y; Nomura, T; Tanaka, T; Yoshida, S; You, H | 1 |
| Bielawski, J; Kim, S; Kong, Y; Li, J; Yang, H; Zhou, B | 1 |
| Caprariello, AV; Dunn, JF; Hoghooghi, V; Koebel, A; Kotra, LP; Morgan, ML; Ousman, SS; Plemel, JR; Rogers, JA; Stys, PK; Tsutsui, S; Wee Yong, V | 1 |
| Azizi, M; Borhani-Haghighi, M; Kashani, IR; Madadi, S; Nekoonam, S; Noorzehi, G; Pasbakhsh, P; Tahmasebi, F | 1 |
| Cao, L; Ma, CG; Miao, Q; Song, LJ; Sui, RX; Wang, J; Wang, Q; Xiao, BG; Xiao, W; Yu, JW | 1 |
| Gu, Y; Huang, J; Huang, R; Jin, M; Li, Q; Wan, B; Xu, X; Zhang, Y | 1 |
| Bartenstein, P; Beyer, C; Brendel, M; Daerr, M; Deussing, M; Focke, C; Hoornaert, C; Kipp, M; Nack, A; Nedelcu, J; Nyamoya, S; Ponsaerts, P; Rominger, A; Schmitz, C | 1 |
| Araújo, SM; da Cruz-Höfling, MA; Luna, RL; Nunes, AK; Peixoto, CA; Raposo, C | 1 |
| Harding, HP; Huang, G; Jamison, S; Li, J; Lin, W; Lin, Y; Ron, D | 1 |
| Bénardais, K; Gai, L; Gudi, V; Neßler, J; Prajeeth, CK; Singh, V; Skripuletz, T; Stangel, M | 1 |
| El-Sawalhi, MM; Ghaiad, HR; Nooh, MM; Shaheen, AA | 1 |
| Becker, B; Beyer, C; Clarner, T; Hochstrasser, T; Kipp, M; Scheld, M; Wagenknecht, N | 1 |
| Al-Dalahmah, O; Davies, J; Hillis, JM; Mundim, MV; Szele, FG | 1 |
| Beyer, C; Clarner, T; Hochstrasser, T; Höflich, KM; Kipp, M; Nyamoya, S; Schmitz, C | 1 |
| Abdollahi, M; Golab, F; Mehdizadeh, M; Mostafaie, A; Ravan, H; Sanadgol, N; Sharifzadeh, M | 1 |
| Biancotti, JC; de Vellis, J; Kumar, S | 1 |
| Chew, LJ; Schmitz, T | 1 |
| Ballantyne, P; Bandin, DL; Berghofer, P; Fordham, S; Gregoire, MC; Katsifis, A; Mattner, F; Pham, T; Quinlivan, M; Staykova, M; Willenborg, DO | 1 |
| Boretius, S; Brück, W; Dallenga, T; Escher, A; Frahm, J; Nessler, S; Stadelmann, C; Tammer, R; Wrzos, C | 1 |
| Cross, AH; Haldar, JP; Klein, RS; Song, SK; Sun, P; Trinkaus, K; Tu, TW; Wang, Q; Wang, Y; Xie, M; Yeh, FC | 1 |
| Boretius, S; Ehrenreich, H; Frahm, J; Ghezzi, P; Hagemeyer, N; Ott, C; Simons, M; Sperling, S; Von Streitberg, A; Welpinghus, H | 1 |
| Arnett, HA; Matsushima, GK; Suzuki, K; Ting, JP; Wang, Y | 1 |
| Arnett, HA; Hellendall, RP; Laubach, VE; Matsushima, GK; Sherman, P; Suzuki, K; Ting, JP | 1 |
1 review(s) available for cuprizone and Innate Inflammatory Response
| Article | Year |
|---|---|
Cytokines and myelination in the central nervous system.
Topics: Alzheimer Disease; Animals; Brain; Brain Ischemia; Central Nervous System; Cuprizone; Cytokines; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Humans; Hyperoxia; Infant, Newborn; Inflammation; Multiple Sclerosis; Myelin Sheath; Schizophrenia; Signal Transduction | 2008 |
1 trial(s) available for cuprizone and Innate Inflammatory Response
| Article | Year |
|---|---|
The neuroprotective potential of mesenchymal stem cells from bone marrow and human exfoliated deciduous teeth in a murine model of demyelination.
Topics: Animals; Bone Marrow; Corpus Callosum; Cuprizone; Disease Models, Animal; Female; Humans; Inflammation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Neuroprotection; Oligodendroglia; Tooth, Deciduous | 2023 |
46 other study(ies) available for cuprizone and Innate Inflammatory Response
| Article | Year |
|---|---|
Cuprizone feed formulation influences the extent of demyelinating disease pathology.
Topics: Animal Feed; Animals; Astrocytes; Body Weight; Chelating Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; DNA Damage; Gliosis; Inflammation; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Oligodendroglia; Reproducibility of Results | 2021 |
Paeonol Ameliorates Cuprizone-Induced Hippocampal Demyelination and Cognitive Deficits through Inhibition of Oxidative and Inflammatory Events.
Topics: Acetophenones; Animals; Cognition; Cuprizone; Disease Models, Animal; Hippocampus; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Oxidative Stress | 2022 |
TRPV2: A Key Player in Myelination Disorders of the Central Nervous System.
Topics: Animals; Calcium Channels; Central Nervous System; Cuprizone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Inflammation; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendroglia; Remyelination; TRPV Cation Channels | 2022 |
Cuprizone-mediated demyelination reversibly degrades voiding behavior in mice while sparing brainstem reflex.
Topics: Animals; Brain Stem; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Humans; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Quality of Life; Reflex; Urination | 2022 |
Ursolic Acid Enhances Myelin Repair in Adult Mice Brains and Stimulates Exhausted Oligodendrocyte Progenitors to Remyelinate.
Topics: Animals; Anti-Inflammatory Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Inflammation; Interleukin-10; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendrocyte Precursor Cells; Oligodendroglia; Tumor Necrosis Factor-alpha; Ursolic Acid | 2022 |
Sulforaphane, an Nrf-2 Agonist, Modulates Oxidative Stress and Inflammation in a Rat Model of Cuprizone-Induced Cardiotoxicity and Hepatotoxicity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Catalase; Chemical and Drug Induced Liver Injury; Cuprizone; Inflammation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar | 2023 |
Potassium channels at the crossroads of neuroinflammation and myelination in experimental models of multiple sclerosis.
Topics: 4-Aminopyridine; Animals; Cuprizone; Inflammation; Mice; Models, Theoretical; Multiple Sclerosis; Neuroinflammatory Diseases; Potassium Channels | 2023 |
Modulating miR-146a Expression by Hydrogen Sulfide Ameliorates Motor Dysfunction and Axonal Demyelination in Cuprizone-Induced Multiple Sclerosis.
Topics: Animals; Cuprizone; Hydrogen Sulfide; Inflammation; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Multiple Sclerosis; NF-kappa B | 2023 |
Inhibition of SUMOylation promotes remyelination and reduces IL-17 mediated autoimmune inflammation: Novel approach toward treatment of inflammatory CNS demyelinating disease.
Topics: Animals; Cell Differentiation; Central Nervous System Diseases; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Humans; Inflammation; Interleukin-17; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendroglia; Remyelination; Sumoylation; Transcription Factors | 2023 |
Nrf2 deficiency increases oligodendrocyte loss, demyelination, neuroinflammation and axonal damage in an MS animal model.
Topics: Animals; Axons; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Inflammation; Mice; Mice, Knockout; Multiple Sclerosis; NF-E2-Related Factor 2; Oligodendroglia; Oxidative Stress | 2020 |
Phloroglucinol derivative compound 21 attenuates cuprizone-induced multiple sclerosis mice through promoting remyelination and inhibiting neuroinflammation.
Topics: Animals; Astrocytes; Brain; Cuprizone; Cytokines; Disease Models, Animal; Drug Discovery; Inflammation; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Myelin Basic Protein; Oligodendroglia; Phloroglucinol; Remyelination; Treatment Outcome | 2020 |
Deletion of Voltage-Gated Calcium Channels in Astrocytes during Demyelination Reduces Brain Inflammation and Promotes Myelin Regeneration in Mice.
Topics: Animals; Astrocytes; Brain; Calcium Channel Blockers; Calcium Channels; Cuprizone; Demyelinating Diseases; Female; Inflammation; Male; Mice; Mice, Knockout; Myelin Sheath; Nimodipine; Remyelination | 2020 |
Repurposing of Secukinumab as Neuroprotective in Cuprizone-Induced Multiple Sclerosis Experimental Model via Inhibition of Oxidative, Inflammatory, and Neurodegenerative Signaling.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Cuprizone; Demyelinating Diseases; Inflammation; Male; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Sheath; Neurodegenerative Diseases; Neuroprotective Agents; Oligodendroglia; Oxidative Stress; Remyelination | 2020 |
Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis.
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoids; Chelating Agents; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Remyelination; Spinal Cord | 2020 |
Intranasal anti-caspase-1 therapy preserves myelin and glucose metabolism in a model of progressive multiple sclerosis.
Topics: Animals; Caspase 1; Cuprizone; Disease Models, Animal; Fluorodeoxyglucose F18; Glucose; Humans; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis, Chronic Progressive; Myelin Sheath | 2021 |
Aquaporin-4 Expression during Toxic and Autoimmune Demyelination.
Topics: Animals; Aquaporin 4; Autoimmune Diseases; Brain; Brain Injuries; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Mice; Multiple Sclerosis; Myelin Sheath; Neuromyelitis Optica | 2020 |
Coenzyme Q10 enhances remyelination and regulate inflammation effects of cuprizone in corpus callosum of chronic model of multiple sclerosis.
Topics: Animals; Behavior, Animal; Biomarkers; Chronic Disease; Corpus Callosum; Cuprizone; Cytokines; Demyelinating Diseases; Disease Models, Animal; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Sheath; Oxidative Stress; Remyelination; Ubiquinone | 2021 |
Inflammation-driven glial alterations in the cuprizone mouse model probed with diffusion-weighted magnetic resonance spectroscopy at 11.7 T.
Topics: Animals; Brain; Choline; Cuprizone; Diffusion Magnetic Resonance Imaging; Female; Immunohistochemistry; Inflammation; Inositol; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Neuroglia | 2021 |
ACT-1004-1239, a first-in-class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases.
Topics: Animals; Cell Differentiation; Cuprizone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunomodulation; Inflammation; Male; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Sheath; Myelin-Oligodendrocyte Glycoprotein; Oligodendroglia; Receptors, CXCR; Stem Cells | 2021 |
Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment.
Topics: Animals; Axons; Central Nervous System; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation; Interferon-gamma; Male; Mice; Oligodendroglia; Remyelination | 2021 |
Changes in leptin, serotonin, and cortisol after eight weeks of aerobic exercise with probiotic intake in a cuprizone-induced demyelination mouse model of multiple sclerosis.
Topics: Animals; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Female; Hydrocortisone; Inflammation; Leptin; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Physical Conditioning, Animal; Probiotics; Serotonin | 2021 |
Endogenous neural stem cells modulate microglia and protect against demyelination.
Topics: Animals; Cell Differentiation; Corpus Callosum; Cuprizone; Demyelinating Diseases; Inflammation; Lateral Ventricles; Ligands; Mice, Transgenic; Microglia; Neural Stem Cells; Neuroprotection; Receptors, Cell Surface | 2021 |
Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes.
Topics: Animals; Astrocytes; Biological Transport; Chronic Disease; Cicatrix; Copper; Cuprizone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Inflammation; Ligands; Membrane Transport Proteins; Mice, Knockout; Multiple Sclerosis; Myelin Sheath; Nerve Growth Factors; Receptor, trkB; Up-Regulation; White Matter | 2021 |
NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes.
Topics: Animals; Apoptosis Regulatory Proteins; Astrocytes; Calcium-Binding Proteins; Cuprizone; Disease Models, Animal; Inflammasomes; Inflammation; Lysophosphatidylcholines; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; NLR Family, Pyrin Domain-Containing 3 Protein | 2017 |
Yokukansan Reduces Cuprizone-Induced Demyelination in the Corpus Callosum Through Anti-inflammatory Effects on Microglia.
Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Corpus Callosum; Cuprizone; Cytokines; Demyelinating Diseases; Disease Models, Animal; Drugs, Chinese Herbal; Female; Inflammation; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Oligodendroglia | 2017 |
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Topics: Animals; Apoptosis; Brain; Chimera; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Fingolimod Hydrochloride; Gene Expression; Gliosis; Indans; Inflammation; Male; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Neuroprotective Agents; Oxadiazoles; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors; White Matter | 2018 |
Biochemically altered myelin triggers autoimmune demyelination.
Topics: Animals; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Encephalitis; Hashimoto Disease; Humans; Hydrolases; Inflammation; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Multiple Sclerosis; Myelin Sheath | 2018 |
Microglia polarization by methylprednizolone acetate accelerates cuprizone induced demyelination.
Topics: Animals; Chemokine CXCL10; Cuprizone; Demyelinating Diseases; Inflammation; Methylprednisolone; Mice; Microglia; Multiple Sclerosis | 2018 |
Protective and therapeutic role of Bilobalide in cuprizone-induced demyelination.
Topics: Animals; Autoantibodies; Behavior, Animal; Corpus Callosum; Cuprizone; Cyclopentanes; Cytokines; Demyelinating Diseases; Disease Models, Animal; Furans; Ginkgolides; Humans; Immunity, Humoral; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Oligodendroglia | 2019 |
Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation.
Topics: Animals; Cell Differentiation; Central Nervous System; Cuprizone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gallic Acid; Humans; Inflammation; Jumonji Domain-Containing Histone Demethylases; Mice; Microglia; Multiple Sclerosis; Myelin Sheath; Neurogenesis; Oligodendroglia; Remyelination | 2019 |
Expression of Translocator Protein and [18F]-GE180 Ligand Uptake in Multiple Sclerosis Animal Models.
Topics: Animals; Astrocytes; Axons; Biomarkers; Carbazoles; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation; Ligands; Mice, Inbred C57BL; Mitochondria; Monocytes; Multiple Sclerosis; Neuroglia; Receptors, GABA; RNA, Messenger | 2019 |
Sildenafil (Viagra) protective effects on neuroinflammation: the role of iNOS/NO system in an inflammatory demyelination model.
Topics: Animals; Cuprizone; Cyclic GMP; Demyelinating Diseases; Glutathione S-Transferase pi; Inflammation; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Myelin Sheath; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones | 2013 |
PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases.
Topics: Animals; Axons; Cell Death; Cell Survival; Cuprizone; Cytoprotection; Demyelinating Diseases; eIF-2 Kinase; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Inflammation; Interferon-gamma; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendroglia; Signal Transduction; Tacrolimus; Tremor | 2014 |
Long-term impact of neonatal inflammation on demyelination and remyelination in the central nervous system.
Topics: Animals; Animals, Newborn; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Female; Inflammation; Lipopolysaccharides; Male; Mice, Inbred C57BL; Microglia; Myelin Sheath; Oligodendroglia; Pregnancy; Random Allocation; RNA, Messenger | 2014 |
Resveratrol Promotes Remyelination in Cuprizone Model of Multiple Sclerosis: Biochemical and Histological Study.
Topics: Animals; Biomarkers; Brain; Cuprizone; Disease Models, Animal; Inflammation; Male; Mice, Inbred C57BL; Mitochondria; Motor Activity; Multiple Sclerosis; Myelin Sheath; Oxidative Stress; Remyelination; Resveratrol; Stilbenes | 2017 |
Thalamus Degeneration and Inflammation in Two Distinct Multiple Sclerosis Animal Models.
Topics: Animals; Cuprizone; Encephalomyelitis, Autoimmune, Experimental; Inflammation; Mice; Mice, Inbred C57BL; Spinal Cord; Thalamus | 2016 |
Cuprizone demyelination induces a unique inflammatory response in the subventricular zone.
Topics: Animals; Animals, Newborn; Calcium-Binding Proteins; Cell Proliferation; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Female; Galectin 3; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Inflammation; Lateral Ventricles; Male; Mice; Mice, Transgenic; Microfilament Proteins; Monoamine Oxidase Inhibitors; Olfactory Bulb; Oligodendroglia | 2016 |
Acute axonal damage in three different murine models of multiple sclerosis: A comparative approach.
Topics: Amyloid beta-Protein Precursor; Animals; Axons; Brain; Corpus Callosum; Cuprizone; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Microglia; Models, Animal; Multiple Sclerosis; Myelin Sheath; Nerve Degeneration; Spinal Cord | 2016 |
Ellagic acid ameliorates cuprizone-induced acute CNS inflammation via restriction of microgliosis and down-regulation of CCL2 and CCL3 pro-inflammatory chemokines.
Topics: Animals; Calcium-Binding Proteins; Caspase 3; Central Nervous System Diseases; Chemokine CCL2; Chemokine CCL3; Corpus Callosum; Cuprizone; Down-Regulation; Ellagic Acid; Enzyme-Linked Immunosorbent Assay; Inflammation; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Microscopy, Fluorescence; Real-Time Polymerase Chain Reaction | 2016 |
Activation of inflammatory response by a combination of growth factors in cuprizone-induced demyelinated brain leads to myelin repair.
Topics: Animals; Base Sequence; Brain Diseases; Cuprizone; Cytokines; Demyelinating Diseases; DNA Primers; Female; Growth Substances; Immunohistochemistry; Inflammation; Inflammation Mediators; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microscopy, Electron; Myelin Sheath; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Evaluation of [¹²³I]-CLINDE as a potent SPECT radiotracer to assess the degree of astroglia activation in cuprizone-induced neuroinflammation.
Topics: Animals; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Corpus Callosum; Cuprizone; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Microglia; Radioactive Tracers; Receptors, GABA; Tomography, Emission-Computed, Single-Photon; Up-Regulation | 2011 |
Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI.
Topics: Animals; Axons; Blood-Brain Barrier; Brain; Cuprizone; Demyelinating Diseases; Diffusion Tensor Imaging; Discriminant Analysis; Encephalomyelitis, Autoimmune, Experimental; Female; Gliosis; Image Processing, Computer-Assisted; Inflammation; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Multiple Sclerosis; Pertussis Toxin | 2012 |
Quantification of increased cellularity during inflammatory demyelination.
Topics: Animals; Corpus Callosum; Cuprizone; Demyelinating Diseases; Diffusion Tensor Imaging; Inflammation; Magnetic Resonance Imaging; Male; Mice; Myelin Sheath; Nerve Fibers, Myelinated; Trigeminal Nerve | 2011 |
Erythropoietin attenuates neurological and histological consequences of toxic demyelination in mice.
Topics: Amyloid beta-Protein Precursor; Animals; Axons; Cerebral Ventricles; Corpus Callosum; Cuprizone; Demyelinating Diseases; Erythropoietin; Inflammation; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Postural Balance; Psychomotor Performance | 2012 |
Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration.
Topics: Animals; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Oligodendroglia; Oligonucleotide Array Sequence Analysis; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
The protective role of nitric oxide in a neurotoxicant-induced demyelinating model.
Topics: Animals; Apoptosis; Cell Movement; Corpus Callosum; Cuprizone; Demyelinating Diseases; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Microscopy, Fluorescence; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodendroglia; Tyrosine | 2002 |