cuprizone has been researched along with Astrocytosis in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.38) | 18.2507 |
| 2000's | 13 (30.95) | 29.6817 |
| 2010's | 23 (54.76) | 24.3611 |
| 2020's | 5 (11.90) | 2.80 |
| Authors | Studies |
|---|---|
| Anyaegbu, C; Bartlett, CA; Fitzgerald, M; Hellewell, SC; Lins, B; McGonigle, T; Papini, M; Toomey, LM; Warnock, A; Wright, AJ | 1 |
| Bakhtiari, N; Hojati, V; Honarvar, F; Javan, M; Zare, L | 1 |
| Damania, A; Kim, J; Lukomska, A; Rheaume, BA; Sajid, MS; Trakhtenberg, EF; Xing, J | 1 |
| Baumann, L; Beecken, M; Greiner, T; Heinig, L; Joost, S; Kipp, M; Manzhula, K; Schauerte, S; Vankriekelsvenne, E | 1 |
| Almuslehi, MSM; Coorssen, JR; Gyengesi, E; Mahns, DA; Myers, SJ; Sen, MK; Shortland, PJ | 1 |
| Behrangi, N; Brendel, M; Jiangshan, Z; Kaye, J; Kipp, M; Nedelcu, J; Reinbach, C; Riedler, P; Rominger, A; Schmitz, C | 1 |
| Abe, Y; Murakami, M; Nagahama, M; Niikura, T | 1 |
| Bielawski, J; Kim, S; Kong, Y; Li, J; Yang, H; Zhou, B | 1 |
| Budde, T; Cerina, M; Daldrup, T; Fernandez-Orth, J; Göbel, K; Gudi, V; Herrmann, AM; Lesting, J; Meuth, P; Meuth, SG; Narayanan, V; Pape, HC; Schiffler, P; Seidenbecher, T; Skripuletz, T; Stangel, M; Wiendl, H | 1 |
| Fang, Z; Huang, Q; Kong, J; Xu, H; Yang, L; Zhang, J | 1 |
| Aksnes, L; Bø, L; Myhr, KM; Nystad, AE; Torkildsen, O; Wergeland, S | 1 |
| Beyer, C; Clarner, T; Janssen, K; Kipp, M; Rickert, M | 1 |
| Berneman, Z; Daans, J; Guglielmetti, C; Hens, N; Kara, F; Orije, J; Ponsaerts, P; Praet, J; Santermans, E; Van der Linden, A; Verhoye, M | 1 |
| Azimzadeh, M; Beyer, C; Clarner, T; Golestani, A; Kashani, IR; Omidi, N; Pasbakhsh, P; Zendedel, A | 1 |
| Bai, CB; Benson, E; Dutta, R; Edberg, D; Kidd, G; Macklin, WB; Medicetty, S; Roholt, A; Sun, S; Trapp, B | 1 |
| Ács, P; Bölcskei, K; Kemény, Á; Komoly, S; Pintér, E; Pohóczky, K; Sághy, É; Sándor, Z; Sétáló, G; Sipos, É; Szőke, É | 1 |
| Doi, T; Hamanoue, M; Hayakawa, K; Imamura, O; Morioka, K; Nagao, M; Ogata, T; Okazaki, R; Sawada, Y; Takishima, K; Tanaka, S | 1 |
| Gingele, S; Gudi, V; Skripuletz, T; Stangel, M; Tejedor, LS; Wostradowski, T | 1 |
| Binder, DK; Hasselmann, JPC; Khalaj, AJ; Lapato, AS; Szu, JI; Tiwari-Woodruff, SK | 1 |
| Baumgartner, W; Beyer, C; Braun, A; Clarner, T; Hieble, A; Johann, S; Kipp, M; Norkute, A | 1 |
| Gudi, V; Hildebrandt, H; Koutsoudaki, PN; Moharregh-Khiabani, D; Skripuletz, T; Stangel, M; Trebst, C | 1 |
| Baumgartner, W; Beyer, C; Clarner, T; Dang, J; Groebe, A; Kipp, M | 1 |
| Millet, V; Moiola, CP; Pasquini, JM; Pasquini, LA; Soto, EF | 1 |
| Bussmann, JH; Gudi, V; Koutsoudaki, PN; Lindner, M; Moharregh-Khiabani, D; Pul, R; Skripuletz, T; Stangel, M | 1 |
| Gudi, V; Kotsiari, A; Koutsoudaki, PN; Moharregh-Khiabani, D; Skripuletz, T; Skuljec, J; Stangel, M; Trebst, C | 1 |
| Brinkmann, BG; Brück, W; Glaser, R; Guedes, RC; Jürgens, T; Klinker, F; Liebetanz, D; Merkler, D; Paulus, W; Sereda, MW; Stadelmann-Nessler, C | 1 |
| Baumgartner, W; Beyer, C; Clarner, T; Dang, J; Gingele, S; Kipp, M; Pott, F | 1 |
| Bartucci, S; Franco, P; Gallo, V; Pasquini, J; Silvestroff, L; Soto, E | 1 |
| Catania, A; Cicirata, F; Cicirata, V; La Delia, F; Parenti, R; Tress, O; Willecke, K; Zappalà, A | 1 |
| Boretius, S; Brück, W; Dallenga, T; Escher, A; Frahm, J; Nessler, S; Stadelmann, C; Tammer, R; Wrzos, C | 1 |
| Li, J; Steelman, AJ; Thompson, JP | 1 |
| Amor, S; Berger, K; Beyer, C; Clarner, T; Denecke, B; Diederichs, F; Gan, L; Kipp, M; van der Valk, P | 1 |
| Bø, L; Myhr, KM; Mørk, SJ; Torkildsen, Ø; Wergeland, S | 1 |
| Armstrong, RC; Hibbits, N; Le, TQ; Yoshino, J | 1 |
| Bauer, K; Baumgärtner, W; Berger, K; Gudi, V; Hackstette, D; Kipp, M; Pul, R; Skripuletz, T; Stangel, M; Voss, E | 1 |
| Bacia, A; Soliven, B; Wollmann, R | 1 |
| Arnett, HA; Plant, SR; Ting, JP | 1 |
| Barnum, SR; Briggs, DT; Ingersoll, SA; Martin, BK; Martin, CB | 1 |
| Baumgärtner, W; Heine, S; Lienenklaus, S; Lindner, M; Stangel, M; Trebst, C; Weiss, S | 1 |
| Binder, MD; Butzkueven, H; Carmeliet, P; Cate, HS; Cipriani, T; Gresle, MM; Jokubaitis, VG; Kemper, D; Kilpatrick, TJ; Prieto, AL | 1 |
| Cammer, W; Zhang, H | 1 |
| D'Ercole, AJ; Gao, X; Gillig, TA; Matsushima, GK; Popko, B; Ye, P | 1 |
42 other study(ies) available for cuprizone and Astrocytosis
| Article | Year |
|---|---|
Cuprizone feed formulation influences the extent of demyelinating disease pathology.
Topics: Animal Feed; Animals; Astrocytes; Body Weight; Chelating Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; DNA Damage; Gliosis; Inflammation; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Oligodendroglia; Reproducibility of Results | 2021 |
Ursolic Acid Enhances Myelin Repair in Adult Mice Brains and Stimulates Exhausted Oligodendrocyte Progenitors to Remyelinate.
Topics: Animals; Anti-Inflammatory Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Inflammation; Interleukin-10; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendrocyte Precursor Cells; Oligodendroglia; Tumor Necrosis Factor-alpha; Ursolic Acid | 2022 |
Post-injury born oligodendrocytes incorporate into the glial scar and contribute to the inhibition of axon regeneration.
Topics: Axons; Cuprizone; Demyelinating Diseases; Gliosis; Humans; Nerve Regeneration; Oligodendroglia; Retinal Ganglion Cells | 2023 |
The Cuprizone Mouse Model: A Comparative Study of Cuprizone Formulations from Different Manufacturers.
Topics: Animals; Body Weight; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice; Mice, Inbred C57BL; Myelin Sheath | 2023 |
Suppression of the Peripheral Immune System Limits the Central Immune Response Following Cuprizone-Feeding: Relevance to Modelling Multiple Sclerosis.
Topics: Adaptive Immunity; Animals; Brain; Computational Biology; Cuprizone; Cytokines; Demyelinating Diseases; Disease Models, Animal; Gliosis; Immune System; Male; Mice; Mice, Inbred C57BL; Microglia; Mitochondria; Multiple Sclerosis; Oligodendroglia | 2019 |
Laquinimod ameliorates secondary brain inflammation.
Topics: Animals; Brain; Cuprizone; Disease Models, Animal; Encephalitis; Female; Gliosis; Mice, Inbred C57BL; Multiple Sclerosis; Quinolones | 2020 |
Humanin affects object recognition and gliosis in short-term cuprizone-treated mice.
Topics: Animals; Brain; Cuprizone; Demyelinating Diseases; Gliosis; Intracellular Signaling Peptides and Proteins; Male; Maze Learning; Memory, Short-Term; Mice; Microglia; Recognition, Psychology | 2017 |
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Topics: Animals; Apoptosis; Brain; Chimera; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Fingolimod Hydrochloride; Gene Expression; Gliosis; Indans; Inflammation; Male; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Neuroprotective Agents; Oxadiazoles; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors; White Matter | 2018 |
Impairment of frequency-specific responses associated with altered electrical activity patterns in auditory thalamus following focal and general demyelination.
Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Cortex; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Female; Functional Laterality; Geniculate Bodies; Gliosis; Gray Matter; Lysophosphatidylcholines; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Myelin Proteolipid Protein; Neurons; Psychoacoustics; Thalamus | 2018 |
Adenosine Promotes the Recovery of Mice from the Cuprizone-Induced Behavioral and Morphological Changes while Effecting on Microglia and Inflammatory Cytokines in the Brain.
Topics: Adenosine; Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Chelating Agents; Cuprizone; Cytokines; Demyelinating Diseases; Dose-Response Relationship, Drug; Gliosis; Hippocampus; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Oligodendroglia; Psychomotor Performance; Schizophrenia | 2018 |
Effect of high-dose 1.25 dihydroxyvitamin D3 on remyelination in the cuprizone model.
Topics: Animals; Brain; Calcitriol; Cuprizone; Demyelinating Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Female; Gliosis; Mice; Mice, Inbred C57BL; Myelin Proteins; Myelin Sheath; Nogo Proteins; T-Lymphocytes | 2014 |
Absence of CCL2 and CCL3 Ameliorates Central Nervous System Grey Matter But Not White Matter Demyelination in the Presence of an Intact Blood-Brain Barrier.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain; Cells, Cultured; Chemokine CCL2; Chemokine CCL3; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Female; Gliosis; Gray Matter; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Viscera; White Matter | 2016 |
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra.
Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Cuprizone; Demyelinating Diseases; Dipeptides; Disease Models, Animal; Female; Gliosis; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Neuroimaging; Oligodendroglia; Phosphocreatine; Proton Magnetic Resonance Spectroscopy | 2015 |
Regulatory effect of triiodothyronine on brain myelination and astrogliosis after cuprizone-induced demyelination in mice.
Topics: Animals; Brain; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice, Inbred C57BL; Myelin Proteins; Myelin Sheath; Oligodendroglia; Triiodothyronine | 2016 |
A mouse model for testing remyelinating therapies.
Topics: Animals; Axons; Brain; Calcium-Binding Proteins; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Immunosuppressive Agents; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Monoamine Oxidase Inhibitors; Myelin Proteolipid Protein; Regeneration; Sirolimus; Time Factors; Triiodothyronine; White Matter | 2016 |
TRPA1 deficiency is protective in cuprizone-induced demyelination-A new target against oligodendrocyte apoptosis.
Topics: Adenomatous Polyposis Coli; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Body Weight; Brain; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Fibroblast Growth Factor 2; Gene Expression Regulation; Gliosis; Mice; Mice, Knockout; Monoamine Oxidase Inhibitors; Myelin Basic Protein; Nerve Tissue Proteins; Oligodendroglia; Signal Transduction; TRPA1 Cation Channel | 2016 |
The crucial role of Erk2 in demyelinating inflammation in the central nervous system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cuprizone; Cytokines; Demyelinating Autoimmune Diseases, CNS; Disease Models, Animal; Embryo, Mammalian; Enzyme Activation; Female; Gene Expression Regulation; Gliosis; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Monoamine Oxidase Inhibitors; Motor Disorders; Myelin Basic Protein; Nestin; Neuroglia; Neurons; Rats; Rats, Wistar | 2016 |
The Effect of Stereotactic Injections on Demyelination and Remyelination: a Study in the Cuprizone Model.
Topics: Animals; Blood-Brain Barrier; Cerebral Cortex; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Gray Matter; Injections, Intraventricular; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Myelin Sheath; Stereotaxic Techniques | 2017 |
Chronic demyelination-induced seizures.
Topics: Animals; Aquaporin 4; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Electroencephalography; Gliosis; Hippocampus; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Multiple Sclerosis; Neurons; Seizures | 2017 |
Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus.
Topics: Aging; Animals; Astrocytes; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Hippocampus; Immunohistochemistry; Indoles; Male; Mice; Mice, Inbred C57BL; Microglia; Microscopy, Electron; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Demyelination of the hippocampus is prominent in the cuprizone model.
Topics: Animals; Astrocytes; Biomarkers; Chelating Agents; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Fibers, Myelinated; Nerve Tissue Proteins; Neurotoxins; Wallerian Degeneration | 2009 |
Cuprizone treatment induces distinct demyelination, astrocytosis, and microglia cell invasion or proliferation in the mouse cerebellum.
Topics: Animals; Cell Proliferation; Cerebellum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Monoamine Oxidase Inhibitors; Myelin Proteolipid Protein; RNA, Messenger; Time Factors | 2009 |
Partial inhibition of proteasome activity enhances remyelination after cuprizone-induced demyelination.
Topics: Acetylcysteine; Animals; Corpus Callosum; Cuprizone; Cysteine Proteinase Inhibitors; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Regeneration; Neurotoxins; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Treatment Outcome | 2009 |
Cerebellar cortical demyelination in the murine cuprizone model.
Topics: Animals; Astrocytes; Cerebellar Cortex; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice; Mice, Inbred C57BL; Microglia; Myelin Sheath; Nerve Fibers, Myelinated; Oligodendroglia; Time Factors | 2010 |
Regional differences between grey and white matter in cuprizone induced demyelination.
Topics: Animals; Astrocytes; Brain; Cerebral Cortex; Chelating Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Disease Progression; Gliosis; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Nerve Fibers, Myelinated; Nerve Regeneration; Neurotoxins; Oligodendroglia; Stem Cells; Time Factors | 2009 |
Propagation of spreading depression inversely correlates with cortical myelin content.
Topics: Animals; Astrocytes; Cerebral Cortex; Cortical Spreading Depression; Cuprizone; Demyelinating Diseases; Electroencephalography; Encephalomyelitis, Autoimmune, Experimental; Female; Functional Laterality; Glial Fibrillary Acidic Protein; Gliosis; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Neuregulin-1; Rats; Rats, Inbred Lew | 2009 |
Cuprizone effect on myelination, astrogliosis and microglia attraction in the mouse basal ganglia.
Topics: Age Factors; Analysis of Variance; Animals; Basal Ganglia; Cell Count; Cell Proliferation; Cuprizone; Demyelinating Diseases; Female; Gliosis; Immunohistochemistry; Male; Mice; Microglia; Myelin Proteins; Myelin Sheath; Nerve Fibers, Myelinated; Oligodendroglia; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Cuprizone-induced demyelination in CNP::GFP transgenic mice.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Astrocytes; Brain; Cell Count; Cell Proliferation; Cuprizone; Demyelinating Diseases; Glial Fibrillary Acidic Protein; Gliosis; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Myelin Basic Protein; Neurons; Oligodendroglia; Promoter Regions, Genetic | 2010 |
Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Animals, Newborn; Brain; Connexins; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Developmental; Gliosis; HeLa Cells; Humans; Immunoprecipitation; Mice; Mice, Inbred C57BL; Myelin Basic Protein; Myelin Sheath; Neuronal Plasticity; Oligodendroglia; Transfection | 2010 |
Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI.
Topics: Animals; Axons; Blood-Brain Barrier; Brain; Cuprizone; Demyelinating Diseases; Diffusion Tensor Imaging; Discriminant Analysis; Encephalomyelitis, Autoimmune, Experimental; Female; Gliosis; Image Processing, Computer-Assisted; Inflammation; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Multiple Sclerosis; Pertussis Toxin | 2012 |
Demyelination and remyelination in anatomically distinct regions of the corpus callosum following cuprizone intoxication.
Topics: Animals; Axons; Brain; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Inbred C57BL; Microglia; Myelin Sheath; Nerve Tissue Proteins; Oligodendroglia; Weight Loss | 2012 |
Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Animals; Calcium-Binding Proteins; Chelating Agents; Corpus Callosum; Cuprizone; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Female; Gliosis; Histocompatibility Antigens Class II; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Middle Aged; Multiple Sclerosis; Myelin Proteolipid Protein; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Tissue Proteins; RNA, Messenger | 2012 |
The cuprizone model: regional heterogeneity of pathology.
Topics: Animals; Cerebral Cortex; Complement System Proteins; Corpus Callosum; Cuprizone; Demyelinating Diseases; Female; Gliosis; Hypoxia-Inducible Factor 1, alpha Subunit; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Microglia; Mitochondria; Multiple Sclerosis; Myelin Sheath; Oligodendroglia | 2012 |
Astrogliosis during acute and chronic cuprizone demyelination and implications for remyelination.
Topics: Animals; Cell Proliferation; Chondroitin Sulfate Proteoglycans; Cicatrix; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Myelin Basic Protein; Statistics as Topic; Time Factors | 2012 |
Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination.
Topics: Animals; Astrocytes; Axons; Brain; Corpus Callosum; Cuprizone; Demyelinating Diseases; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Transgenic; Microglia; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Regeneration; Nerve Tissue Proteins | 2013 |
K+ channel blockade impairs remyelination in the cuprizone model.
Topics: 4-Aminopyridine; Animals; Astrocytes; Chelating Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Myelin Basic Protein; Myelin Sheath; Nerve Regeneration; Neuroglia; Oligodendroglia; Potassium Channel Blockers; Potassium Channels; Stem Cells | 2004 |
Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination.
Topics: Animals; Astrocytes; Cell Count; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Encephalitis; Gliosis; Glutathione S-Transferase pi; Glutathione Transferase; Inflammation Mediators; Isoenzymes; Lymphotoxin-alpha; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Regeneration; Oligodendroglia; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Astrocyte-specific expression of a soluble form of the murine complement control protein Crry confers demyelination protection in the cuprizone model.
Topics: Animals; Apoptosis; Astrocytes; Brain; Chelating Agents; Complement System Proteins; Corpus Callosum; Cuprizone; Cytoprotection; Demyelinating Autoimmune Diseases, CNS; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Regeneration; Oligodendroglia; Receptors, Complement; Receptors, Complement 3b; Time Factors | 2007 |
Lack of interferon-beta leads to accelerated remyelination in a toxic model of central nervous system demyelination.
Topics: Animals; Astrocytes; Axons; Chelating Agents; Cuprizone; Disease Models, Animal; Gliosis; Interferon-beta; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Microscopy, Electron, Transmission; Multiple Sclerosis; Myelin Sheath; Recovery of Function | 2007 |
Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.
Topics: Animals; Axl Receptor Tyrosine Kinase; c-Mer Tyrosine Kinase; Cell Death; Cell Survival; Cells, Cultured; Chelating Agents; Coculture Techniques; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Fibers, Myelinated; Neurotoxins; Oligodendroglia; Oncogene Proteins; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases | 2008 |
Atypical localization of the oligodendrocytic isoform (PI) of glutathione-S-transferase in astrocytes during cuprizone intoxication.
Topics: Animals; Astrocytes; Brain; Carbonic Anhydrases; Cuprizone; Female; Glial Fibrillary Acidic Protein; Gliosis; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Male; Mice; Neuronal Plasticity; Oligodendroglia; Pregnancy | 1993 |
Interferon-gamma protects against cuprizone-induced demyelination.
Topics: Animals; Astrocytes; Chelating Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gene Expression; Gliosis; Insulin-Like Growth Factor I; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Myelin Proteins | 2000 |