cudraxanthone-l has been researched along with Atherosclerosis* in 1 studies
1 other study(ies) available for cudraxanthone-l and Atherosclerosis
| Article | Year |
|---|---|
Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata.
The catecholic xanthones and flavonoids 1-13 were isolated from the root bark of Cudrania tricuspidata. Compounds 1 and 3-8 exhibited significant antioxidant activity against low-density lipoprotein (LDL) oxidation in the thiobarbituric acid-reactive substance (TBARS) assay. Among them, prenylated flavonoids 10-12 showed an inhibitory effect on the NO production and iNOS expression in RAW264.7 cells. Also, compounds 1, 2, 5, 7, 9, and 11 preferentially inhibited hACAT-2 than hACAT-1, whereas compounds 3, 4, 6, and 8 showed a similar specificity against hACAT-1 and -2. However, flavonoids 10, 12, and 13 dominantly inhibited hACAT-2, not hACAT-1. Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Catechols; Cell Line; Flavonoids; Humans; Mice; Moraceae; Xanthones | 2006 |